Abstract:
:Leydig cell function, as judged from testosterone concentrations in plasma and in testicular tissue after LH stimulation, was tested in adult rat testes 4 days after brief exposure of the scrotum to 33 degrees and 43 degrees C, respectively. There was no significant difference in basal plasma testosterone concentrations between the two groups of rats but the response to LH stimulation was significantly depressed in rats exposed to 43 decrees C. Morphological examination of the Leydig cells showed an accumulation of lipid droplets in the cytoplasm of the testes exposed to 43 degrees C, indicating a disturbed steroidogenesis. The spermatogenetic arrest seen after heat treatment of the rat testis is discussed in relation to the present finding of impaired Leydig cell function.
journal_name
Andrologiajournal_title
Andrologiaauthors
Damber JE,Bergh A,Janson POdoi
10.1111/j.1439-0272.1980.tb00568.xsubject
Has Abstractpub_date
1980-01-01 00:00:00pages
12-9issue
1eissn
0303-4569issn
1439-0272journal_volume
12pub_type
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