Abstract:
:Chromosome aberration is one of the common causes of male infertility. Isodicentric chromosome is a chromosomal aberration in which two arms of a chromosome are identical in morphology and genetics and connected by two centromeres. We firstly reported a case of infertile male with nonmosaic 46, X, idic (Y) (qter-p11.31::p11.31-qter) but with the sex-determining region Y (SRY). The broken site is the chromosome Y (p11.31). The patients' clinical phenotype was azoospermia and short stature. Fluorescence in situ hybridisation (FISH), chromosomal microarray comparative genomic hybridisation (array CGH) and related molecular analysis were performed. Azoospermia of this case may be caused by the abnormal chromosome structure, which leads to abnormal chromosome synapsis in spermatogenesis. Loss of genes in PAR1 and gain of genes copies in azoospermia factor (AZF) region on the Y chromosome may also contribute to the pathogenesis of azoospermia.
journal_name
Andrologiajournal_title
Andrologiaauthors
Dai Y,Li H,Zhang X,Jia M,Gu Xdoi
10.1111/and.13536subject
Has Abstractpub_date
2020-05-01 00:00:00pages
e13536issue
4eissn
0303-4569issn
1439-0272journal_volume
52pub_type
相关文献
ANDROLOGIA文献大全abstract::The cooperation in cases of childlessness between andrologists and gynecologists is an essential of any treatment. In a short communication it was shown that a special investigation form can be helpful for reciprocal information. This investigation form improves the information rate form 10% to 30%. In some cases the ...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract::The aim of this study was to comprise the effect of catalase on sperm parameters and chromatin in normospermic persons. Semen samples were obtained from fertile men. A certain amount of different concentrations of catalase (0.1, 1, 10, 50, 100, 150 and 200 IU.ml) was added to each vial containing semen. Control group ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13231
更新日期:2019-05-01 00:00:00
abstract::The rate of increase of sperm DNA fragmentation (rsDF) in fresh and frozen-thawed and processed sperm samples after a density gradient for sperm selection was analysed after 0, 0.5, 1.5, 4.5, 6, 24, 48 and 72 h of incubation at 37 °C, in five donors with proven fertility. The results showed that: (i) sperm DNA fragmen...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01022.x
更新日期:2011-12-01 00:00:00
abstract::Recent studies have revealed a high prevalence of leukocytospermia (> 1 x 10(6) white blood cells ml-1 semen) in male infertility patients in the USA and certain European countries, and have implicated white blood cells as a cause of infertility. Since leukocytospermia may often be attributed to male genital-tract inf...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1994.tb00783.x
更新日期:1994-05-01 00:00:00
abstract::The acrosome reaction of human spermatozoa was induced by changes of temperature. Spermatozoa were collected from fertile donors and a patient group, and selected by the "swim-up" method. The spermatozoa were treated in two different ways: Protocol I: 24 hours at room temperature followed by additional incubation at 3...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1991.tb02537.x
更新日期:1991-05-01 00:00:00
abstract::Male infertility affects approximately 30% of infertile couples. As spermatozoa mature in the epididymal lumen, their potential for mobility increases, and their protein, lipid and small RNA (sRNA) content changes, whereas capacitation and fertilisation take place in the female reproductive tract. Both of the latter p...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13989
更新日期:2021-01-25 00:00:00
abstract::Hereditary angioedema is a rare disease, which is caused by deficiency of compleman c1 esterase inhibitor regulatory protein in the compleman system. Priapism is involuntary, painful and prolonged erection of penis more than 4 h without sexual desire. In this case report, we elucidated a patient diagnosed with heredit...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12297
更新日期:2015-06-01 00:00:00
abstract::Methamphetamine has been reported to be an important drug in the field of reproductive toxicology. The aim of this study was to investigate the effects of methamphetamine administrations on sperm morphology, sperm concentration and apoptotic activity inside seminiferous tubule in male rats. Rats were administered a do...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01071.x
更新日期:2011-08-01 00:00:00
abstract::During early development of the human testis the male germ cell first appears as primordial germ cell or gonocyte and enters the prospermatogonial stage after the twelfth week of gestation. Prospermatogonia lack glycogen particles and are connected by intercellular bridges. During the same period in the ovary the fema...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1976.tb02120.x
更新日期:1976-01-01 00:00:00
abstract::This study aimed to assess seminal mast cells in infertile men associated with varicocele (Vx) pre- and post-surgical repair. Forty-five infertile men associated with Vx were subjected to history taking and clinical examination. In addition, semen parameters and seminal mast cells stained with 1% toluidine blue were e...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12625
更新日期:2017-04-01 00:00:00
abstract::A procedure was designed for purification of a human seminal plasma-specific antigen (HSP-antigen) identified by a monoclonal antibody produced in this laboratory (mAb 4E6). Pooled human seminal plasma was fractionated by consecutively applied methods: affinity chromatography on Lentil lectin sepharose, gel chromatogr...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1993.tb02724.x
更新日期:1993-09-01 00:00:00
abstract::Chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS) is a multifactorial problem affecting men of all ages and demographics. Currently, there is a relative dearth of epidemiological information on CPPS. It is clear that patients with CPPS have a dismal quality of life and many have benefited only minimally from ...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1046/j.1439-0272.2003.00584.x
更新日期:2003-10-01 00:00:00
abstract::Sperm motility and vitality are decreased in male genital tract infection. Uropathogenic Escherichia coli (UPEC) are frequently associated with sperm parameter loss, but there are no reports to date regarding the effects of different E. coli isolates on human spermatozoa. The aim of this work was to compare the effect...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12167
更新日期:2014-10-01 00:00:00
abstract::In eutherian mammalian spermatozoa the capacitation is coupled to a specific type of metabolism, that is glycolysis or oxidative respiration. A cytochemical study was carried out on cytochrome oxidase and lactate dehydrogenase in human spermatozoa collected at different times during in vitro capacitation. Human sperma...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1987.tb02346.x
更新日期:1987-06-01 00:00:00
abstract::A partial cDNA sequence of the boar 28, 29-kDa proacrosin-binding protein was determined. The desired sequence was amplified and obtained by RT-PCR followed by nested PCR. The oligonucleotide primers for RT-PCR were designed by deduction from the internal amino acid sequence of the boar proacrosin-binding protein. An ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1046/j.1439-0272.2001.00466.x
更新日期:2001-11-01 00:00:00
abstract::Previous studies showed that exposure to stress or nicotine induced reproductive impairment in male rats. Here, we assessed the effect of an antioxidant (vitamin E) on nicotine-, stress- and nicotine + stress-induced reproductive impairment in male rats. Forty-eight male albino Wistar rats were divided into eight grou...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13050
更新日期:2018-09-01 00:00:00
abstract::DNA specific fluorochrome (Hoechst 33342 and 33258) as non-toxic stains, have been widely used to measure cell density and proliferation, detect sperm-egg fusion, and observe the development of pre-implantation embryos. It has been reported that Hoechst 33342 at a concentration of 10 micrograms ml-1 had significant in...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1992.tb02632.x
更新日期:1992-05-01 00:00:00
abstract::Methylenetetrahydrofolate reductase (MTHFR), the key enzyme of the folate metabolic pathway, has been reported to be five times more active in the testicles compared to other organs in adult mice. The aim of this study was to investigate the relationship between MTHFR c.677C>T and c.1298A>C polymorphisms and infertili...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12380
更新日期:2015-11-01 00:00:00
abstract::The authors present the histological features of the testes in 1,609 cases of male sterility. In 485 cases (30.1%), histological changes were found, which did not warrant treatment. The histologic pattern of the testes was normal in only 39% of the cases of azoospermia; and only these patients were qualified for surge...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1978.tb03057.x
更新日期:1978-09-01 00:00:00
abstract::Based on cytological criteria, three types of A-Spermatogonia may be distinguished in the germinal epithelium of normal men. Cells belonging to Type I conform to A pale spermatogonia and those classified as Type II conform to A dark-spermatogonia according to Clermont ()963). Type III-spermatogonia do not meet the cri...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1978-07-01 00:00:00
abstract::The necessity to check up exactly the procedure in vasectomy by the so called - Hamburg Model - is demonstrated by 4 cases. Although these patients were sterilized we could prove fertility on spermiogram, and observed pregnancy in 3 cases. Consequences in matter of law for the surgeon is pointed out. ...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::Infertility occurs in up to 54% of men with bilateral undescended testes. Orchiectomy is considered the best therapeutic approach, especially when cryptorchidism is diagnosed in adulthood, due to a high risk of malignancy. A 33-year-old man was referred with a clinical presentation of empty scrotum and an ultrasonogra...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12936
更新日期:2018-03-01 00:00:00
abstract::Linear mucus penetration of spermatozoa from 75 arbitrary selected men was evaluated using a non-commercial bovine cervix mucus preparation in the same way as Penetrak, but using round glass capillary tubes instead of flat plastic tubes. The mean penetration value was 28.7 +/- 7.10 mm in 90 min and the mean sperm dens...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1990-07-01 00:00:00
abstract::Next to clinical investigations, the evaluation of male fertility relies mainly on detailed sperm analyses, for example, cell counting, motility, cell morphology and vitality testing. The manual creation of a spermiogram is time- and material-consuming. Therefore, reliable high-throughput systems that may be substitut...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13149
更新日期:2019-02-01 00:00:00
abstract::The effects of incubation with caffeine at final concentration of 0.5 and 5.0 mM for 30 min at ambient temperature were examined in three normal semen samples and three from asthenozoospermic men. A 50 frames/s microcinematographic analysis of the sperm motility was performed and two characteristic parameters of the t...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1982.tb02295.x
更新日期:1982-09-01 00:00:00
abstract::The routine spermiogram parameters of 3432 patients born between 1952 and 1971 in the region of Leipzig were determined between January 1975 and March 2000. The patient group aged 24-35 years was characterized by low mobility and relocation living in the main centre of chemical industry with enormous environmental pol...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1046/j.0303-4569.2003.00590.x
更新日期:2003-12-01 00:00:00
abstract::In cases of varicocele the reverse venous blood flow can be detected by the use of the Doppler-stethoscope in a simple way. Applied to the basic examination of fertility patients this method has proved to be a valuable non-invasive screening in the evaluation of varicoceles including cases with minor clinical symptoms...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1980-09-01 00:00:00
abstract::Reproductive dysfunction is one of the most prevalent diabetes complications. Draceana arborea is known to enhance sexual function in diabetic rats, but the underlying mechanisms have not been thoroughly elucidated. This study examined the effects of D. arborea on some reproductive complications of diabetes in rats. A...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13381
更新日期:2019-11-01 00:00:00
abstract::Conventional sperm freezing methods perform best when freezing sperm samples containing at least hundreds of spermatozoa. In this severe male factor infertility case series, we examined the reproductive outcomes in 12 intracytoplasmic sperm injection cases where spermatozoa used were frozen in Cell Sleepers. Cell Slee...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12434
更新日期:2016-03-01 00:00:00
abstract::In this study, a short stature male with infertility is reported. Semen analysis and serum concentrations of FSH, LH, T and PRL were estimated. Chromosome analysis was performed on lymphocytes obtained from both the male and his parents. Cytogenomic studies were performed by fluorescent in situ hybridisation and the C...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12278
更新日期:2015-05-01 00:00:00