Dynamics of sperm DNA damage in fresh versus frozen-thawed and gradient processed ejaculates in human donors.

abstract：:The effect of chronic chloroquine administration on prostaglandin E1 (PGE1) and human chorionic gonadotropin (hCG) stimulation of testosterone secretion by the rat Leydig cells was studied. Adult albino (Wistar strain) rats were injected with 4 mg/kg body weight of chloroquine phosphate every other day for 30 days. At...

journal_title：Andrologia

authors： Nduka EU,Dada OA

更新日期：1987-09-01 00:00:00

abstract：:Sildenafil citrate is a selective phosphodiesterase 5 (PDE-5) inhibitor and partial phosphodiesterase 6 inhibitor prescribed for erectile dysfunction. Post-marketing case reports of nonarteritic anterior ischaemic optic neuropathy (NAION) over the past few years suggest a potential link with PDE-5 inhibitors. We repor...

journal_title：Andrologia

authors： El-Domyati MM,El-Fakahany HM,Morad KE

更新日期：2009-10-01 00:00:00

abstract：:The aim of this study was to evaluate the production of artefacts during preparation and observation of human sperm for ultrastructural morphology and analyse the possible reasons of causing these artefacts. Under the scanning electron microscopy, damaged sperm heads (crack or/and rupture), necks (head-neck or head-mi...

journal_title：Andrologia

authors： Zhu WJ

更新日期：2018-09-01 00:00:00

abstract：:Corpus cavernosum smooth muscle cells (CCSMCs) are important functional cells for penile erection. We evaluated the effect of transforming growth factor β1 (TGFβ1) and hepatocyte growth factor (HGF) on the viability and apoptosis of CCSMCs in vitro. CCSMCs from healthy male Sprague Dawley rats were randomly divided in...

journal_title：Andrologia

authors： Liu T,Peng YF,Jia C,Yang BH,Tao X,Fang X,Zhong W

更新日期：2015-11-01 00:00:00

abstract：:Leydig cell tumours (LCTs) of the testis are rare. Their origin is still unknown. This case report describes a potential relationship between LCT and prolonged exposure to Finasteride. ...

journal_title：Andrologia

authors： Berthold D,Lhermitte B,Uffer M,Doerfler A

更新日期：2012-05-01 00:00:00

abstract：:The aim of the study was to examine the effects of two-year testosterone replacement therapy on cognitive functioning, emotional state and quality of life in young and middle-aged men with hypogonadotropic hypogonadism. Nineteen males diagnosed with hypogonadotropic hypogonadism participated in the study. Cognitive fu...

journal_title：Andrologia

authors： Lašaitė L,Čeponis J,Preikša RT,Žilaitienė B

更新日期：2017-04-01 00:00:00

abstract：:For the 13 abnormalities under consideration, the mean percentages were found to be the following: irregular head (15.2), microcephalic (9.8), elongated head (5.9), coiled tail (5.8), bent tail (4.7), thin head (4.6), cytoplasmic remains (3.2), macrocephalic (1.6), short tail (1.1), no tail (0.6), duplicate tail (0.5)...

journal_title：Andrologia

authors： Schwartz D,Mayaux MJ,Guihard-Moscato ML,Spira A,Jouannet P,Czyglik F,David G

更新日期：1984-09-01 00:00:00

abstract：:A procedure was designed for purification of a human seminal plasma-specific antigen (HSP-antigen) identified by a monoclonal antibody produced in this laboratory (mAb 4E6). Pooled human seminal plasma was fractionated by consecutively applied methods: affinity chromatography on Lentil lectin sepharose, gel chromatogr...

journal_title：Andrologia

authors： Dimitrova D,Kehayov I,Kyurkchiev S

更新日期：1993-09-01 00:00:00

abstract：:The study investigated the association between lower urinary tract symptoms (LUTS) and sexual dysfunction in ageing men. It was a cross-sectional study in an unselected consecutive sample of 398 men aged >40 years attending a urology clinic. LUTS and sexual function were assessed by validated symptom scales, including...

journal_title：Andrologia

authors： Tsao CW,Cha TL,Lee SS,Tang SH,Wu ST,Tsui KH,Sun GH

更新日期：2008-12-01 00:00:00

abstract：:Pre- and postdexamethasone triiodothyronine (T3), thyroxine (T4), and TSH levels of thirteen patients with psychogenic sexual dysfunction and thirteen controls were studied. Patients showed lowered T4 levels in comparison with the control group whereas T3 and TSH levels did not differ significantly. Dexamethasone had ...

journal_title：Andrologia

authors： Noder M,Rupprecht R,Rupprecht M,Rupprecht C,Hornstein OP

更新日期：1990-01-01 00:00:00

abstract：:Docetaxel (DTX) has been used in cancer treatments for several decades, but it results in many adverse apoptotic effects through excessive production of reactive oxygen species (ROS) in some tissue including the kidney and testes. We aimed to investigate potential modulatory roles of melatonin (MEL) and selenium (Se) ...

journal_title：Andrologia

authors： Baş E,Nazıroğlu M

更新日期：2019-09-01 00:00:00

abstract：:Azoospermia factor (AZF) genes are involved in spermatogenesis. Deletions in the region of these genes have been recognised as a major genetic cause of infertility due to defects in spermatogenesis. Klinefelter syndrome (KS) is the other main cause of male infertility. This study was performed to establish a novel met...

journal_title：Andrologia

authors： Bahrami Zadegan S,Dabbagh Bagheri S,Joudaki A,Samiee Aref MH,Saeidian AH,Abiri M,Zeinali S

更新日期：2017-12-28 00:00:00

abstract：:The plasma level of testosterone, FSH and LH were determined simultaneously in spermatic and cubital veins in 12 patients with varicocele. The testosterone levels in spermatic veins were 13.4 +/- 5.3 times higher than in cubital veins. FSH and LH levels were higher in cubital than in spermatic vein. No correlation was...

journal_title：Andrologia

authors： Bablok L,Janczewski Z,Czaplicki M

更新日期：1985-07-01 00:00:00

abstract：:Primary seminal vesicle adenocarcinoma is a rare malignancy of the male genito-urinary system with only a few confirmed reported cases. Initial tissue diagnostic modality is often a core biopsy specimen. Here, we report this rare entity in a 50-year-old male, highlighting the histomorphological and immunohistochemical...

journal_title：Andrologia

authors： Bhardwaj N,Rastogi P,Attri VS,Bora GS,Gorsi U

更新日期：2020-04-01 00:00:00

abstract：:150 randomized patients from the andrology department of the University Hospital for Gynecology and Obstetrics, Graz, Austria have been evaluated concerning their motivation, cooperation and compliance. To gain basic data from andrology patients and to analyze consequences after the first clinical examination was one ...

journal_title：Andrologia

authors： Pusch HH

更新日期：1985-03-01 00:00:00

abstract：:Sex hormones have been proposed as a possible risk factor for the development and growth of meningiomas. Hormonal therapy plays a fundamental role in the treatment of male-to-female transgenders and needs to be continued after sex reassignment surgery. Usually, this treatment leads to no adverse events; however, its i...

journal_title：Andrologia

authors： Ter Wengel PV,Martin E,Gooren L,Den Heijer M,Peerdeman SM

更新日期：2016-12-01 00:00:00

abstract：:Almost all testicular germ cell tumours are proved to originate from carcinoma in situ cells. Infertility is one of the factors that increase the risk of carcinoma in situ. The reported prevalence for carcinoma in situ from different parts of the world is 0-3.7% in infertile men. This retrospective study was performed...

journal_title：Andrologia

authors： Soltanghoraee H,Pourkeramati F,Khoddami M,Amirjannati N,Akhondi MM,Soltani A

更新日期：2014-09-01 00:00:00

abstract：:There are no efficient and noninvasive clinical tests to distinguish between obstructive azoospermia (OA) and non-obstructive azoospermia (NOA). Epididymal protease inhibitor (Eppin) protein is secreted specifically by testes and epididymides in male reproductive system. It does not exist in seminal plasma of patients...

journal_title：Andrologia

authors： Liu B,Su S,Wang P,Niu X,Yang X,Zhang W,Wang Z,Wang X

更新日期：2011-10-01 00:00:00

abstract：:Chronic inflammatory conditions of the genital tract are still unsatisfactorily recognised in the workup of male infertility due to inappropriate definitions and inconsistent diagnostic criteria. The most popular term used for description of both, infections and inflammation in the genital tract is MAGI (male accessor...

journal_title：Andrologia

authors： Haidl G,Haidl F,Allam JP,Schuppe HC

更新日期：2019-04-01 00:00:00

abstract：:Methamphetamine has been reported to be an important drug in the field of reproductive toxicology. The aim of this study was to investigate the effects of methamphetamine administrations on sperm morphology, sperm concentration and apoptotic activity inside seminiferous tubule in male rats. Rats were administered a do...

journal_title：Andrologia

authors： Nudmamud-Thanoi S,Thanoi S

更新日期：2011-08-01 00:00:00

abstract：:This work aimed to assess seminal plasma reactive oxygen species (ROS)-antioxidants relationship with varicocele grade in infertile men with oligoasthenoteratozoospermia (OAT). The study included 89 infertile OAT men with varicocele divided into grade I (n = 22) and grade II (n = 43), grade III (n = 24) and compared w...

journal_title：Andrologia

authors： Mostafa T,Anis T,El Nashar A,Imam H,Osman I

更新日期：2012-02-01 00:00:00

abstract：:Sperm morphology has been consistently correlated with fertilisation success or failure. The clinical relevance of the percentage normal spermatozoa has been a widely discussed topic amongst infertility specialists and scientists. This study aimed to evaluate the role of sperm morphology as an indicator of additional ...

journal_title：Andrologia

authors： Franken DR

更新日期：2015-08-01 00:00:00

abstract：:Infertility is a major health problem which affects approximately 22% of married couples in reproductive age. Chromosomal defects are the most common genetic abnormalities in infertile men, with an incidence of cytogenetic abnormalities ranging from 2.1% to 15.5%. We describe here the clinical and cytogenetic studies ...

journal_title：Andrologia

authors： Ananthapur V,Avvari S,Veena K,Sujatha M,Jyothy A

更新日期：2014-05-01 00:00:00

abstract：:The aim of this study was to compare the effectiveness of antioxidants including cysteamine (2.5, 7.5 mm), hyaluronan (0.25, 1 mg ml(-1) ) and fetuin (5, 10 mg ml(-1) ) in the freezing of Brown Swiss bull semen. The best percentages of CASA motilities were achieved with 10 mg ml(-1) of fetuin and 2.5 mm of cysteamine....

journal_title：Andrologia

authors： Sarıözkan S,Tuncer PB,Büyükleblebici S,Bucak MN,Cantürk F,Eken A

更新日期：2015-03-01 00:00:00

abstract：:Microscopy has been used in the routine evaluation of sperm metabolism. Nevertheless, it has limited capacity to preview male fertility. As calorimetry may be used to evaluate directly the metabolic activity of a biological system, the aim of this study was to use microcalorimetry as an additive method for sperm metab...

journal_title：Andrologia

authors： Vasconcelos AB,Santana MA,Santos AM,Santoro MM,Lagares MA

更新日期：2010-04-01 00:00:00

abstract：:The effects of incubation with caffeine at final concentration of 0.5 and 5.0 mM for 30 min at ambient temperature were examined in three normal semen samples and three from asthenozoospermic men. A 50 frames/s microcinematographic analysis of the sperm motility was performed and two characteristic parameters of the t...

journal_title：Andrologia

authors： Serres C,Feneux D,David G

更新日期：1982-09-01 00:00:00

abstract：:Men with Down syndrome are considered as infertile although the causes of infertility are not known in detail yet. Although this constitutes a general rule there are three confirmed cases of parenting by fathers with Down syndrome. Many investigators have addressed the causes of infertility and their studies indicate ...

journal_title：Andrologia

authors： Stefanidis K,Belitsos P,Fotinos A,Makris N,Loutradis D,Antsaklis A

更新日期：2011-10-01 00:00:00

abstract：:Insulin-like factor 3 (INSL3) has an important role in the human reproductive system; however, its detailed function is still mysterious. We aimed to investigate the possibility of expression of RXFP2 receptor on human spermatozoa and to determine the anti-apoptotic and antioxidant mechanism derived the binding of INS...

journal_title：Andrologia

authors： Shokri S,Tavalaee M,Ebrahimi SM,Ziaeipour S,Nasr-Esfahani MH,Nejatbakhsh R

更新日期：2020-10-01 00:00:00

abstract：:Sirolimus is used as a powerful immunosuppressant drug in patients after organ transplantation. It was shown to block spermatogenesis by interrupting the stem cell factor/c-kit system. Oligozoospermia was shown in single patients. In addition, a decrease of testosterone and an increase of gonadotropin levels were obse...

journal_title：Andrologia

authors： Skrzypek J,Krause W

更新日期：2007-10-01 00:00:00

abstract：:The dicentric Y chromosome is the most common cytogenetically visible structural abnormality of Y chromosome. The sites of break and fusion of dicentric Y are variable, but break and fusion at Yq12 (proximal to the pseudoautosomal region 2/PAR 2) is very rare. Dicentric Y chromosome is unstable during cell division an...

journal_title：Andrologia

authors： Kumar P,Jain M,Kalsi AK,Halder A

更新日期：2018-03-01 00:00:00