Microcinematographic analysis of the motility of human spermatozoa incubated with caffeine.

Abstract:

:The effects of incubation with caffeine at final concentration of 0.5 and 5.0 mM for 30 min at ambient temperature were examined in three normal semen samples and three from asthenozoospermic men. A 50 frames/s microcinematographic analysis of the sperm motility was performed and two characteristic parameters of the trajectories, the progression velocity (Vp) and the amplitude of lateral head displacement (Ah), were measured. At the lower concentration (0.5 mM) no significant effects on the overall mean values (i.e. for all spermatozoa analyzed over the 6 samples) of Vp Ah were found. However, at 5.0 mM a significant reduction in the overall mean Vp was noted. The individual responses were variable between the 6 samples, but only in two of the asthenozoospermic samples and one normal ejaculate were the slow-swimming (less than 20 micrometer/s) spermatozoa accelerated by caffeine treatment. In other samples a reduction in the velocity of faster-swimming spermatozoa was observed. It would seem preferable to reserve caffeine treatment only for severe cases of asthenozoospermia where the distribution of sperm velocities of skewed towards low values.

journal_name

Andrologia

journal_title

Andrologia

authors

Serres C,Feneux D,David G

doi

10.1111/j.1439-0272.1982.tb02295.x

subject

Has Abstract

pub_date

1982-09-01 00:00:00

pages

454-60

issue

5

eissn

0303-4569

issn

1439-0272

journal_volume

14

pub_type

杂志文章
  • Treatment of male infertility with human gonadotrophins: selection of cases, management and results.

    abstract::To obtain optimal results with gonadotrophic therapy (HMG/hCG) in infertile males, strict selection of patients is of paramount importance. The use of algorithmic schemes permits the exclusion of patients with primary testicular failure, genetic and non-endocrine causes of infertility. This paper describes a retrospec...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1979.tb02216.x

    authors: Lunenfeld B,Olchovsky D,Tadir Y,Glezerman M

    更新日期:1979-09-01 00:00:00

  • Implications of prostate inflammation on male fertility.

    abstract::The prostate is the seat of three major causes of morbidity: benign prostatic hyperplasia, prostate cancer and prostatitis, three conditions in which inflammation has been implicated. A state of inflammation of the prostate gland, originally incited by an infection, an autoimmune response, a neurogenic stimulus or ano...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13093

    authors: Motrich RD,Salazar FC,Breser ML,Mackern-Oberti JP,Godoy GJ,Olivera C,Paira DA,Rivero VE

    更新日期:2018-12-01 00:00:00

  • The Estonian version of the National Institutes of Health chronic prostatitis symptom index.

    abstract::Our aim was to establish the Estonian version of the National Institutes of Health chronic prostatitis symptom index (NIH-CPSI), and to examine its validity and applicability in chronic prostatitis patients as well as in community-based study. The questionnaire was tested in 54 category III prostatitis patients. In ad...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2006.00723.x

    authors: Korrovits P,Punab M,Mehik A,Mändar R

    更新日期:2006-06-01 00:00:00

  • [Motivation and compliance of andrology patents].

    abstract::150 randomized patients from the andrology department of the University Hospital for Gynecology and Obstetrics, Graz, Austria have been evaluated concerning their motivation, cooperation and compliance. To gain basic data from andrology patients and to analyze consequences after the first clinical examination was one ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Pusch HH

    更新日期:1985-03-01 00:00:00

  • Genetic analysis of the human Insulin-like 3 gene: absence of mutations in a Greek paediatric cohort with testicular maldescent.

    abstract::This study investigated the hypothesis that genetic alterations of the human insulin-like 3 (INSL3) gene are associated with testicular maldescent (TMD). Genomic DNA was extracted and amplified from peripheral blood samples of 170 unrelated children with all possible phenotypical expressions of TMD and 50 volunteers w...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.12184

    authors: Mamoulakis C,Georgiou I,Dimitriadis F,Tsounapi P,Giannakis I,Chatzikyriakidou A,Antypas S,Sofras F,Takenaka A,Sofikitis N

    更新日期:2014-01-01 00:00:00

  • Assessment of preclinical effect of (+)-catechin hydrate on sexual function: An in silico and in vivo study.

    abstract::Considering dopamine-enhancing effect of (+)-catechin, the present study was designed to evaluate dopamine-2 (D2) receptor agonistic and phosphodiesterase-5 (PDE5) enzyme inhibitory effects in in silico and effect on male sexual function of Sprague Dawley rats in vivo. (+)-Catechin and standard (sildenafil and bromocr...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13737

    authors: Rai A,Gill M,Kinra M,Dsouza LA,Sumalatha S,Raj S,Shetty R,Nandakumar K,Chamallamudi MR,Kumar N

    更新日期:2020-07-02 00:00:00

  • Estramustine binding protein in human benign prostatic hypertrophy.

    abstract::Using a highly sensitive radioimmunoassay (RIA) of estramustine binding protein (EMBP) with the antibody raised against rat-EMBP, the concentration of EMBP in human benign prostatic hypertrophy (BPH) tissue was evaluated. Using mechanical separation procedure, EMBP was found significantly higher in the epithelium (10....

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1990.tb01990.x

    authors: Shiina H,Mizutani M,Ishibe T

    更新日期:1990-07-01 00:00:00

  • Mobility shift assay of calcium-binding proteins of mouse epididymal spermatozoa.

    abstract::The calcium-binding proteins (CBPs) of mouse epididymal spermatozoa were analysed by mobility changes in the presence of added Ca2+ in two-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The expression patterns of relatively high molecular weight CBPs (Mr > 20 kDa) were different bet...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1046/j.1439-0272.2001.00419.x

    authors: Gye MC,Park S,Kim YS,Ahn HS

    更新日期:2001-07-01 00:00:00

  • Pentoxifylline increases sperm penetration into zona-free hamster oocytes without increasing the acrosome reaction.

    abstract::Several drugs have been used to stimulate human sperm motility, including 3-deoxy-adenosine, caffeine, and pentoxifylline. Pentoxifylline is an inhibitor of the phosphodiesterase and may stimulate sperm motility by increasing the intracellular levels of cAMP. In this study we have evaluated the effect of pentoxifyllin...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1993.tb02743.x

    authors: Morales P,Llanos M,Yovich JL,Cummins JM,Vigil P

    更新日期:1993-11-01 00:00:00

  • Reproductive immunology: 4. The effect of seminal plasma from immunologic infertile men on in vitro lymphocyte cultures.

    abstract::The seminal plasma of 31 patients were examined for the presence of sperm antibodies and for inhibitory properties on the transformation rates of donor lymphocytes cultured in vitro. Twenty five (80%) of the men revealed apart from fertile semen, no sperm antibody activities while six (20%) patients showed high sperma...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1982.tb03105.x

    authors: Franken DR,Slabber CF

    更新日期:1982-03-01 00:00:00

  • Toxic environmental chemicals in human semen: analytical method and case studies.

    abstract::In 1982, 89 men from all over the FRG participated in an investigation of sperm density and the presence of selected persistent environmental chemicals in their semen. Semen concentrations for the following chemicals were measured: lead, cadmium, hexachlorobenzene (HCBC), a-hexachlorocyclohexane (a-BHC), DDT and metab...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Stachel B,Dougherty RC,Lahl U,Schlösser M,Zeschmar B

    更新日期:1989-05-01 00:00:00

  • Leptin exists in tubuli seminiferi and in seminal plasma.

    abstract::Leptin is a 167-amino acid protein that stimulates gonadotrophin-releasing hormone secretion and exerts indirect effects on the gonads via neuropeptide Y, NPY. Recent research has suggested that leptin may also have an effect on testosterone secretion. To investigate the role of leptin in reproduction, leptin in testi...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1046/j.1439-0272.2002.00501.x

    authors: Glander HJ,Lammert A,Paasch U,Glasow A,Kratzsch J

    更新日期:2002-09-01 00:00:00

  • Outcome of microsurgical testicular sperm extraction in familial idiopathic nonobstructive azoospermia.

    abstract::The aim of the study was to evaluate the sperm retrieval rate by microsurgical testicular sperm extraction (TESE) in familial idiopathic nonobstructive azoospermia (NOA). One hundred and nineteen patients with idiopathic NOA who underwent microsurgical TESE over the past 5 years were included. Patients were then divid...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12378

    authors: Arafa MM,ElBardisi HT,AlSaid SS,Majzoub A,AlMalki AH,ElRobi I,AlAnsari AA

    更新日期:2015-11-01 00:00:00

  • Comparison of different mathematical models to assess seasonal variations in the longevity of DNA integrity of cooled-stored stallion sperm.

    abstract::Dynamic assessment of sperm DNA fragmentation (SDF) has shown to give fuller understanding of stallion semen quality; however, there have been limited attempts to use this parameter to investigate seasonal changes in productive functions. The aims of this study were to: (a) establish a reliable mathematical model to d...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13545

    authors: Ortiz I,Quiñones-Pérez C,Hidalgo M,Consuegra C,Diaz-Jimenez M,Dorado J,Vega-Pla JL,Crespo F

    更新日期:2020-05-01 00:00:00

  • Therapeutic options in male genital tract inflammation.

    abstract::Chronic inflammatory conditions of the genital tract are still unsatisfactorily recognised in the workup of male infertility due to inappropriate definitions and inconsistent diagnostic criteria. The most popular term used for description of both, infections and inflammation in the genital tract is MAGI (male accessor...

    journal_title:Andrologia

    pub_type: 杂志文章,评审

    doi:10.1111/and.13207

    authors: Haidl G,Haidl F,Allam JP,Schuppe HC

    更新日期:2019-04-01 00:00:00

  • Ethanol-extracted Cameroonian propolis: Antiproliferative effects and potential mechanism of action in prostate cancer.

    abstract::The present study was conducted to evaluate in vitro and in vivo antiproliferative potential of the Cameroonian propolis and to elucidate its underlying mechanism. In vitro, ethanol-extracted propolis (EEP) was tested on cell growth, cell proliferation, cell cycle, cell death mechanism and cell migration. The cell cyc...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.13698

    authors: Zingue S,Maxeiner S,Rutz J,Ndinteh DT,Chun FK,Fohouo FT,Njamen D,Blaheta RA

    更新日期:2020-10-01 00:00:00

  • Protective effects of Eugenia jambolana extract versus N-acetyl cysteine against cisplatin-induced damage in rat testis.

    abstract::To assess the protective effects of Eugenia jambolana extract (EJE) or N-acetyl cysteine (NAC) on testis, cisplatin (CIS, 5 mg kg(-1) bw, single dose) was administered either alone or along with EJE (25 mg kg(-1) bw, alternate day) or NAC (150 mg kg(-1) bw, Day 1 and 4) for 7 days. Significant alterations in serum LH,...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12247

    authors: Anand H,Misro MM,Sharma SB,Prakash S

    更新日期:2015-03-01 00:00:00

  • Isolation method of Leydig cells from mature male Djungarian hamsters (Phodopus sungorus) and their steroidogenic activity in vitro.

    abstract::For studies addressing the functions of Leydig cells, isolated cells are often better suited than intact animals. Here, the isolation procedure of Leydig cells from adult male Djungarian hamsters (Phodopus sungorus) is described. Cells were isolated using a procedure involving enzymatic dissociation and Percoll-gradie...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Niedziela M,Lerchl A

    更新日期:1999-05-01 00:00:00

  • Berberine inhibits experimental varicocele-induced cell cycle arrest via regulating cyclin D1, cdk4 and p21 proteins expression in rat testicles.

    abstract::The aim of this study was to uncover the protective effect of berberine (BBR), an antioxidant chemical, on experimental varicocele (VCL)-induced adverse effects on cell cycle machinery during early germ cells mitosis. To follow-up this study, 30 mature male Wistar rats were divided into control-sham, nontreated VCL, 5...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12984

    authors: Amin M,Razi M,Sarrafzadeh-Rezaei F,Shalizar Jalali A,Najafi G

    更新日期:2018-02-14 00:00:00

  • [Sperm centrifugation in azoospermia?].

    abstract::In cases of azoospermia especially after vasectomy the investigation of the seminal sediment investigation is necessary. Exclusive on this way it is possible to find some side dispersed spermatozoa. The described case deals with a pregnancy about 48 days following vasectomy. Postoperative the sperm sediment investigat...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:

    authors: Schirren C

    更新日期:1984-07-01 00:00:00

  • Leukocytospermia in male infertility patients in China.

    abstract::Recent studies have revealed a high prevalence of leukocytospermia (> 1 x 10(6) white blood cells ml-1 semen) in male infertility patients in the USA and certain European countries, and have implicated white blood cells as a cause of infertility. Since leukocytospermia may often be attributed to male genital-tract inf...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1994.tb00783.x

    authors: Wang AW,Politch J,Anderson D

    更新日期:1994-05-01 00:00:00

  • Functional characterisation of a natural androgen receptor missense mutation (N771H) causing human androgen insensitivity syndrome.

    abstract::Androgen insensitivity syndrome (AIS) is an X-linked disorder due to mutations of androgen receptor (AR) gene. Various AR mutations have been identified, and the characterisation of these mutations greatly facilitates our understanding of AR structure-function. In this study, we have analysed an AR missense mutation (...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2011.01219.x

    authors: Cai J,Cai LQ,Hong Y,Zhu YS

    更新日期:2012-05-01 00:00:00

  • Acid-extracted glycoproteins in human seminal coagulum.

    abstract::Protein in intact coagulum of fresh human ejaculate was extracted by 0.25 N HCl, the condition used for extraction of sperm basic proteins. About 75% of the total coagulum protein was found to be acid-extractable and therefore so-called coagulum basic proteins (CBP). The CBP were glycosylated and entirely distinguisha...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1983.tb00158.x

    authors: Kusamran T,Surakarnkul R

    更新日期:1983-07-01 00:00:00

  • Clinical and cytogenomic studies in a case of infertility associated with a nonmosaic dicentric Y chromosome.

    abstract::In this study, a short stature male with infertility is reported. Semen analysis and serum concentrations of FSH, LH, T and PRL were estimated. Chromosome analysis was performed on lymphocytes obtained from both the male and his parents. Cytogenomic studies were performed by fluorescent in situ hybridisation and the C...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12278

    authors: Cui YX,Wang WP,Li TF,Li WW,Wu QY,Li N,Zhang C,Yao Q,Hu YA,Xia XY

    更新日期:2015-05-01 00:00:00

  • Assessment of seminal mast cells in infertile men with varicocele after surgical repair.

    abstract::This study aimed to assess seminal mast cells in infertile men associated with varicocele (Vx) pre- and post-surgical repair. Forty-five infertile men associated with Vx were subjected to history taking and clinical examination. In addition, semen parameters and seminal mast cells stained with 1% toluidine blue were e...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/and.12625

    authors: Mostafa RM,Abol-Magd R,Younis SE,Dessouki OF,Azab M,Mostafa T

    更新日期:2017-04-01 00:00:00

  • Ameliorative effects of curcumin against acute cadmium toxicity on male reproductive system in rats.

    abstract::The aim of the present study was to investigate the ameliorative effect of curcumin (CMN) against acute cadmium chloride (CdCl(2)) toxicity on male reproductive system in rats. CdCl(2) is known to be a heavy metal and potential environmental pollutant. For this purpose, 28 rats were equally divided into four groups; t...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.2012.01273.x

    authors: Oguzturk H,Ciftci O,Aydin M,Timurkaan N,Beytur A,Yilmaz F

    更新日期:2012-08-01 00:00:00

  • Spermagglutinating antibodies: a comparison of three different techniques.

    abstract::In 136 patients tests were performed to demonstrate circulating spermagglutinating antibodies. In patients with "unexplained" infertility (15 cases) antibodies were demonstrated in six (40%) whereas in patients where another cause for infertility was present (101 cases) additional positive spermagglutinating antibodie...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1980.tb00570.x

    authors: Franken DR,Slabber CF

    更新日期:1980-01-01 00:00:00

  • Effect of hypothyroidism on the testes in mature rats and treatment with levothyroxine and zinc.

    abstract::This study was performed to investigate the effect of propylthiouracil (PTU) on rat testis, and to compare the results of the different treatment regimens of levothyroxine and zinc. Twenty sexually mature Wistar albino rats were subjected to PTU for 14 days intraperitoneally to make them hypothyroidic. The effect of P...

    journal_title:Andrologia

    pub_type: 杂志文章,收录出版

    doi:10.1046/j.1439-0272.2000.00324.x

    authors: Tahmaz L,Gökalp A,Kibar Y,Koçak I,Yalçin O,Ozercan Y

    更新日期:2000-03-01 00:00:00

  • Investigations on the influence of prolactin suppression on reproductive function in bulls.

    abstract::In 3 mature bulls 2 injections (i.m.) of 150 mg 2-Br-alpha-ergocryptine (CB-154, Sandoz) within 48 hrs. decreased the plasma prolactin concentrations significantly for about 14 days (first experiment). In a second experiment, where treatment was repeated after 2 weeks, the period of maximal prolaction deficiency could...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1979.tb02149.x

    authors: Stolla R,Schams D,Gimenez T,Leidl W

    更新日期:1979-01-01 00:00:00

  • Purification and characterization of angiotensin converting enzyme-II from bovine seminal plasma.

    abstract::Angiotensin converting enzyme (EC 3.4.15.1) from bovine seminal plasma was shown to exist in two distinct forms. A lower molecular weight form of the enzyme having higher activity was purified to homogeneity. Final recovery of the enzyme was 18.37%. The apparent molecular weight of the enzyme was estimated to be 1.99 ...

    journal_title:Andrologia

    pub_type: 杂志文章

    doi:10.1111/j.1439-0272.1991.tb02569.x

    authors: Sharma M,Singh US

    更新日期:1991-07-01 00:00:00