Abstract:
:In 1982, 89 men from all over the FRG participated in an investigation of sperm density and the presence of selected persistent environmental chemicals in their semen. Semen concentrations for the following chemicals were measured: lead, cadmium, hexachlorobenzene (HCBC), a-hexachlorocyclohexane (a-BHC), DDT and metabolites, dieldrin and polychlorobiphenyls (PBC). Heavy metal analyses were performed by Zeeman-AAS with direct sample measurement. A method for the quantitative determination of chlorinated hydrocarbons in semen by liquid-liquid extraction, clean-up and quantitation by gas chromatography with an electron capture detector. Recovery rates ranged from 72 to 120%. Compound identification in samples was confirmed by negative chemical ionization mass spectrometry. Heavy metals and organochlorine compounds in semen were present in the same concentration range as in blood or other biofluids. Occupational exposure as well as extraordinary environmental exposure appeared to influence semen concentrations. Students in chemistry showed elevated levels of organochlorine compounds. Men who lived in the vicinity of an atmospheric source of heavy metals showed strikingly the vicinity of an atmospheric source of heavy metals showed strikingly elevated levels of semen lead and cadmium. We were unable to find a statistically significant correlation between sperm density and any of the variables examined in this study including: orgonochlorine compounds summed or individually; lead and/or cadmium; and tobacco consumption. Significant correlations were found between the simultaneous occurrence of lead and cadmium and between the simultaneous occurrence of HCB, DDT and DDE.
journal_name
Andrologiajournal_title
Andrologiaauthors
Stachel B,Dougherty RC,Lahl U,Schlösser M,Zeschmar Bsubject
Has Abstractpub_date
1989-05-01 00:00:00pages
282-91issue
3eissn
0303-4569issn
1439-0272journal_volume
21pub_type
杂志文章相关文献
ANDROLOGIA文献大全abstract::The cause of Sertoli cell-only syndrome (SCOS), a condition in which only Sertoli cells line the seminiferous tubules in the testis, is unknown. Three microarray data sets were downloaded from public databases and were used to compare SCOS and control group. A total of 291 genes differentially expressed (Log2 |FC| ≥ 1...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13288
更新日期:2019-08-01 00:00:00
abstract::Parameters were obtained from the reproductive organs of ethanol-fed, gossypol-treated Sprague Dawley rats. The experimental animals were fed either on a normal (15.17%) or low protein (8.00%) diet. Measurements included reproductive organ weights, seminal characteristics, serum concentration of testosterone and histo...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1997.tb00317.x
更新日期:1997-07-01 00:00:00
abstract::In order to elucidate the ultrastructural characteristics of the precursor cell of Leydig cells and its subsequent differentiation, testicular biopsies from two patients with hypogonadotropic hypogonadism, obtained prior to and after treatment with HCG and HMG, were studied in comparison with those of prepubertal, pub...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1979.tb02187.x
更新日期:1979-05-01 00:00:00
abstract::Previous studies have found that the ratio of estradiol to testosterone (E2/T ratio) has a negative effect on sexual function, but the relationship between the E2/T ratio and erection of the penis is not clarified. We conducted a retrospective study of 183 patients with erectile dysfunction and 52 healthy men to inves...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13701
更新日期:2020-10-01 00:00:00
abstract::Several substances can interfere with microtubular function eg. colchicine. Melatonin, a hormone secreted by the pineal gland has similar effects as colchicine on microtubules. In this study melatonin levels were determined in both plasma and seminal plasma of patients with good or impaired motility and forward progre...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1989-09-01 00:00:00
abstract::Polyorchidism is a rare congenital anomaly. Approximately 100 cases have been published to date. We report a case of triorchidism in a 20-year-old man who presented to us with inguinal hernia. There is more than 30% incidence of histological abnormalities in polyorchid testes and 4-7% present with malignancy. The mana...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0272.2009.01026.x
更新日期:2011-04-01 00:00:00
abstract::The purpose of this prospective study was to evaluate Kruger strict morphology and conventional semen analysis in predicting cryosurvival and the progressive motility recovery rate of frozen spermatozoa. Our study included 56 semen samples with >10 million spermatozoa per ejaculate. The main outcome measures were conv...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01141.x
更新日期:2012-05-01 00:00:00
abstract::The aim of this study was to evaluate the hypothalamic-pituitary-gonadal axis functionality on a bodybuilding competitioner before, during and after the use of anabolic-androgenic steroids. A young healthy man was followed up for 4 months. The subject reported his drug administration protocol through periodic intervie...
journal_title:Andrologia
pub_type:
doi:10.1111/and.13107
更新日期:2018-11-01 00:00:00
abstract::This study examines the effect of melatonin on leptin-induced changes in transition of histone to protamine in adult rats during spermatogenesis. Twelve-week-old Sprague-Dawley rats were randomised into control, leptin-, leptin-melatonin-10-, leptin-melatonin-20- and melatonin-10-treated groups with six rats per group...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12814
更新日期:2018-02-01 00:00:00
abstract::The study was performed to measure the impact of testosterone (T) administration on circulating levels of 5alpha-dihydrotestosterone (DHT). Group 1 (32 men; mean age 61 years; mean T 6.9 +/- 1.9 nmol l(-1)) were treated for 15 months with long-acting T undecanoate. Group 2 (23 men, mean age 60 years, mean T 7.6 +/- 2....
journal_title:Andrologia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1439-0272.2008.00857.x
更新日期:2008-10-01 00:00:00
abstract::Air pollution constitutes the largest cause of environmental risks today. At present, no scientific publication linking environmental black soot and derangement in the hypothalamus and testis of rats exists. This study investigated the effect of black soot exposure on hypothalamic and testicular functions of male rats...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13866
更新日期:2020-12-01 00:00:00
abstract::The RNA has been located and proportioned by a spectrophotometric method which absorbs the ultra-violet light. The technique used allows us to execute punctual dosage into the spermatozoon's tail. Each of these punctual dosages makes us realise the RNA localisation; and the sum of these dosages makes us realise the to...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1975-01-01 00:00:00
abstract::Searching for further characteristics of sperm in the diagnosis of male infertility it was examined if ejaculates with "normo-, oligo-, astheno-, terato-" and "azoospermia" showed typical modifications in their triglyceride- and phospholipid contents. The examination was conveyed in spermatozoa and seminal plasma. In ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1984.tb00233.x
更新日期:1984-01-01 00:00:00
abstract::The aim of this study was to analyse the impact of assistance on the comprehensibility and reliability of the Turkish version of International Index of Erectile Function (IIEF). In this study, 458 patients were asked to complete the IIEF questionnaire by themselves during their first visit and then once again during t...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2012.01312.x
更新日期:2013-04-01 00:00:00
abstract::Nonsomatic factors play a significant role in erectile dysfunction. We assessed the impact on men suffering from male factor infertility by employing the validated Self-Esteem and Relationship questionnaire (SEAR) and compared the scores with controls. Men with primary infertility were asked to fill SEAR questionnaire...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13460
更新日期:2020-03-01 00:00:00
abstract::By means of specific RIA unconjugated 5 alpha-androstan-3 alpha, 17 beta-diol (3 alpha-diol) and 5 alpha-androstane-3 beta, 17 beta-diol (3 beta-diol) have been estimated for the first time in normal and pathological human seminal plasma. Testosterone, 5 alpha-dihydrotestosterone and testosterone-glucosiduronate (T, D...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1983-03-01 00:00:00
abstract::Structural heterozygosities of the karyotype have detrimental effects on the meiotic process, resulting very often in impairment of fertility in the carriers. Both male and female germ cell development are affected by chromosomal variability although spermatogenesis seems particularly prone to be affected, probably be...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1992.tb02601.x
更新日期:1992-01-01 00:00:00
abstract::Leydig cell tumours (LCTs) of the testis are rare. Their origin is still unknown. This case report describes a potential relationship between LCT and prolonged exposure to Finasteride. ...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0272.2011.01214.x
更新日期:2012-05-01 00:00:00
abstract::In fertile men, the majority of epididymal spermatozoa acquire the potential to fertilize (assessed with sperm function assays) on passage into the corpus and cauda regions of the epididymis. Although secretions of the epididymal epithelium are clearly important for sperm maturation and survival, their role in this pr...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/j.1439-0272.1998.tb01165.x
更新日期:1998-08-01 00:00:00
abstract::Retraction: 'Aetiology and clinical profile of children with 46, XY differences of sex development at an Indian referral centre' by Vasundhera Chauhan, Rima Dada, Vandana Jain The above article, published online on 8 August 2016 in Wiley Online Library (http://wileyonlinelibrary.com), has been retracted by agreement b...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12663
更新日期:2017-11-01 00:00:00
abstract::In order to investigate whether a hypothalamic disorder cause hypogonadism in male prolactinomas, LH pulsatile secretion was studied in 13 male patients. Serum PRL levels ranged from 186 to 45,000 ng ml-1 before treatment, and all the tumors were macroadenomas. Reduced LH secretion was revealed in 5 of 13 patients, an...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1990-11-01 00:00:00
abstract::Exposure of intact rats to increasing doses of oestradiol-17 beta in the presence of a constant amount of exogenous androgen caused a dose-related increase in the concentration of zinc in the lateral lobes and a decrease in the levels of ventral lobe prolactin binding. These changes occurred concomitantly with a dose-...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1986.tb01819.x
更新日期:1986-09-01 00:00:00
abstract::The rate of increase of sperm DNA fragmentation (rsDF) in fresh and frozen-thawed and processed sperm samples after a density gradient for sperm selection was analysed after 0, 0.5, 1.5, 4.5, 6, 24, 48 and 72 h of incubation at 37 °C, in five donors with proven fertility. The results showed that: (i) sperm DNA fragmen...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01022.x
更新日期:2011-12-01 00:00:00
abstract::Statins are lipid-lowering medications widely used to reduce the risk of cardiovascular diseases. Biochemically, they act by decreasing synthesis of cholesterol via inhibiting 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase. Since 1992, various research studies have investigated the effect of statins on semen quality...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13592
更新日期:2020-07-01 00:00:00
abstract::The spermatological phenomenon of increased exfoliation of immature germ cells (IGC) not commonly known until now, can be defined quantitatively as a number of above 4% IGC in relation to the sperm count. The variable aspect of premature germ cells may be confusing and their degenerative alterations complicate definit...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1987-05-01 00:00:00
abstract::Protein in intact coagulum of fresh human ejaculate was extracted by 0.25 N HCl, the condition used for extraction of sperm basic proteins. About 75% of the total coagulum protein was found to be acid-extractable and therefore so-called coagulum basic proteins (CBP). The CBP were glycosylated and entirely distinguisha...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1983.tb00158.x
更新日期:1983-07-01 00:00:00
abstract::This study scrutinised the ameliorative properties of grape seed extract (GSE) in dexamethasone (DEX)-induced testicular and thyroid dysfunction associated with oxidative stress in male albino rats. Thirty-two healthy adult male albino rats were divided into four groups of eight animals each: normal, DEX control, DEX ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13002
更新日期:2018-06-01 00:00:00
abstract::On the basis of microscopical examination and further differentiation by special stain techniques, a new classification of defects of midpieces and tails of spermatozoa will be presented: First degree disorders i.e. abnormalities of the staining behaviour and minor structural defects, second degree disorders revealing...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1987-07-01 00:00:00
abstract::This investigation was carried out to study the correlation of sperm quality parameters with antioxidant and oxidant status of buffalo bull semen during various stages of cryopreservation. Semen samples were evaluated for sperm parameters (mass motility [MM], concentration [CON], progressive motility [PM], viability [...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12970
更新日期:2018-02-11 00:00:00
abstract::We report an unusual case of recurrent, painful, unilateral gynaecomastia (GM) in an elderly male with relapsing Graves' hyperthyroidism and co-existing primary hypogonadism. This patient presented to the Breast Clinic with a 4-month history of painful, right GM. Malignancy was excluded but T3 was noted to be raised a...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2006.00681.x
更新日期:2006-02-01 00:00:00