Abstract:
:Exposure of intact rats to increasing doses of oestradiol-17 beta in the presence of a constant amount of exogenous androgen caused a dose-related increase in the concentration of zinc in the lateral lobes and a decrease in the levels of ventral lobe prolactin binding. These changes occurred concomitantly with a dose-dependent increase in plasma prolactin levels, and could not be obtained in hypophysectomized rats given the same steroid treatment. In the intact animals a dose-dependent decrease in the responsiveness of the prostaglandin E1-dependent adenylyl cyclase in the ventral lobe was observed, an effect which has earlier been shown to be prolactin mediated. The results indicate that oestrogen has indirect effects on specific parameters of prostate function by inducing a relative hyperprolactinemia. This model may be useful in studying effects of chronically and physiologically elevated levels of endogenous prolactin on the rat prostate.
journal_name
Andrologiajournal_title
Andrologiaauthors
Oldereid NB,Thomassen Y,Rui H,Gordeladze JO,Haug E,Purvis Kdoi
10.1111/j.1439-0272.1986.tb01819.xsubject
Has Abstractpub_date
1986-09-01 00:00:00pages
516-22issue
5eissn
0303-4569issn
1439-0272journal_volume
18pub_type
杂志文章相关文献
ANDROLOGIA文献大全abstract::The techniques of SDS-polyacrylamide slab gel electrophoresis and a sensitive fluorescamine-based method were used to study autoproteolysis of human seminal coagulum at various pH. The major protein bands of 72 and 55 Kd were optimally degraded at pH 7.5. Degradation at pH 3.5 was preceded by a lag period of 30 min. W...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1986.tb01771.x
更新日期:1986-05-01 00:00:00
abstract::Flutamide is a steroid used to treat androgen-dependent disorders and as antiepileptic, but it induces a number of non-desirable side effects. This work was aimed at assaying the effect of flutamide and two novel synthetic steroids on the levels of GABA, glutamine and oxidative stress markers. Male Wistar rats (weight...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01051.x
更新日期:2011-08-01 00:00:00
abstract::The aim of this study was to uncover the protective effect of berberine (BBR), an antioxidant chemical, on experimental varicocele (VCL)-induced adverse effects on cell cycle machinery during early germ cells mitosis. To follow-up this study, 30 mature male Wistar rats were divided into control-sham, nontreated VCL, 5...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12984
更新日期:2018-02-14 00:00:00
abstract::The necessity to check up exactly the procedure in vasectomy by the so called - Hamburg Model - is demonstrated by 4 cases. Although these patients were sterilized we could prove fertility on spermiogram, and observed pregnancy in 3 cases. Consequences in matter of law for the surgeon is pointed out. ...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1981-07-01 00:00:00
abstract::Idiopathic oligoathenoteratozoospermia (iOAT) is a common finding in the evaluation of male infertility. Oxidative stress (OS) may underlie its pathology. Tamoxifen and l-carnitine are used to treat idiopathic male infertility. The aim of this work was to detect the efficacy of tamoxifen and l-carnitine on sperm param...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12333
更新日期:2015-09-01 00:00:00
abstract::The microvasculature of the human testis is closely related to the Leydig cells and the seminiferous tubules. Semi-thin sections of testicular tissue serve as a basis for the computer-aided 3-D reconstruction of the microvasculature, the seminiferous tubules and the Leydig cells. After vascular perfusion with glutaral...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1994.tb00799.x
更新日期:1994-09-01 00:00:00
abstract::Insulin-like factor 3 (INSL3) has an important role in the human reproductive system; however, its detailed function is still mysterious. We aimed to investigate the possibility of expression of RXFP2 receptor on human spermatozoa and to determine the anti-apoptotic and antioxidant mechanism derived the binding of INS...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13715
更新日期:2020-10-01 00:00:00
abstract::Monoclonal and polyclonal antibodies were used in indirect immunofluorescence microscopy to localize vimentin intermediate filaments in the rat seminiferous epithelium. During stages XII-V of the epithelial cycle, the Sertoli cells showed a reaction in the perinuclear area and vimentin-positive extensions, projecting ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1987.tb01920.x
更新日期:1987-11-01 00:00:00
abstract::In this study, the presence of Chlamydia trachomatis, Neisseria gonorrhoeae, Trichomonas vaginalis, Mycoplasma hominis, Mycoplasma genitalium, Ureaplasma urealyticum and Ureaplasma parvumDNA were investigated using real-time multiplex PCR detection kit in the urine samples of 50 patients who presented to the infertili...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13127
更新日期:2018-12-01 00:00:00
abstract::Human ejaculates collected for in vitro procedures show variably rapid increases in osmolality, depending on enzymatic degradation of compounds. Changes in osmolality can affect cell functions due to the energy consuming processes needed to control cell volume. The aim was to examine the effects of a hypotonic challen...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13859
更新日期:2020-12-01 00:00:00
abstract::The numbers of Sertoli and pre-meiotic germ cells in the developing rabbit testis were investigated as an initial step in determining the physiological meaning of the control of cell number in the testis by apoptosis. Sections were stained immunohistochemically for the detection of apoptotic cells and counterstained w...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1046/j.1439-0272.2002.00464.x
更新日期:2002-02-01 00:00:00
abstract::Our previous study found that Chinese chive could significantly (p < 0.01) raise testosterone and nitric oxide (NO) levels in mice serum. However, the specific functional components of this traditional remedy are still unknown. In order to isolate and identify the active constituents from Chinese chive for enhancing t...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13191
更新日期:2019-03-01 00:00:00
abstract::D-chloramphenicol, at concentrations of 20 and 40 micrograms/ml, inhibited over 80% of the newly synthesized mitochondrial proteins expressed by incorporation of 3H-amino acid mixture. At concentrations of 20 and 40 micrograms ml-1, D-chloramphenicol enhanced the collective motility of washed ram spermatozoa. The coll...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1994.tb00815.x
更新日期:1994-11-01 00:00:00
abstract::Iatrogenic obstruction of the vas deferens within the inguinal canal can be managed by direct on-site vasovasostomy. However, in cases with large defect of the vas, the anastomosis may be under tension. Dissecting through the site of a previous hernia repair is tedious, and may lead to recurrence of the hernia. The pr...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2004.00624.x
更新日期:2004-10-01 00:00:00
abstract::Genetic factors that could mediate the pathogenesis of male reproductive disorders are largely unclear. Polymorphisms of cytochrome P4501A1 (CYP1A1), a key enzyme in the extrahepatic metabolism of lipophilic xenobiotics, have been shown to influence susceptibility to xenobiotics. Here, CYP1A1 polymorphisms were invest...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1998.tb01387.x
更新日期:1998-05-01 00:00:00
abstract::Azoospermia factor (AZF) genes on the long arm of the human Y chromosome are involved in spermatogenesis, and microdeletions in the AZF region have been recognised to be the second major genetic cause of spermatogenetic failure resulting in male infertility. While screening for these microdeletions can avoid unnecessa...
journal_title:Andrologia
pub_type: 杂志文章,多中心研究
doi:10.1111/and.12662
更新日期:2017-06-01 00:00:00
abstract::This study aimed to examine the association of herpes zoster (HZ) with androgen deprivation therapy (ADT) use among patients with prostate cancer (PC), using a population-based data set. The study sample for this study was retrieved from the Taiwan Longitudinal Health Insurance Database 2005. We selected 877 patients ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12863
更新日期:2018-03-01 00:00:00
abstract::Maturation arrest (MA) of spermatogenesis is diagnosed on histology as interruption of spermatogenesis before the final stage without impairment of Sertoli or Leydig cells. It is considered a condition of irreversible or absolute infertility. Varicocele, which represents impairment in the testicular venous drainage sy...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01083.x
更新日期:2010-12-01 00:00:00
abstract::Mesterolone, HCG and PMS, clomiphene and various other drugs were administered to 236 subfertile patients with disturbed spermatogenesis. Most of the patients received mesterolone. The effects of the various therapeutic regimes are discussed. Improvement of the sperm count and spermatozoal motility was more frequent a...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1983.tb00205.x
更新日期:1983-01-01 00:00:00
abstract::Using a highly sensitive radioimmunoassay (RIA) of estramustine binding protein (EMBP) with the antibody raised against rat-EMBP, the concentration of EMBP in human benign prostatic hypertrophy (BPH) tissue was evaluated. Using mechanical separation procedure, EMBP was found significantly higher in the epithelium (10....
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1990.tb01990.x
更新日期:1990-07-01 00:00:00
abstract::Cell-free seminal mRNA (cfs-mRNA) exists in the human ejaculate that is proposed as a potential noninvasive procedure to prognosis pathophysiological conditions. This study applied cfs-mRNA of ESX1, ZMYND15 and its target haploid genes (TNP1 and PRM1) to identify the presence of spermatozoa in men with azoospermia. Th...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13483
更新日期:2020-03-01 00:00:00
abstract::This study was performed to investigate the effect of propylthiouracil (PTU) on rat testis, and to compare the results of the different treatment regimens of levothyroxine and zinc. Twenty sexually mature Wistar albino rats were subjected to PTU for 14 days intraperitoneally to make them hypothyroidic. The effect of P...
journal_title:Andrologia
pub_type: 杂志文章,收录出版
doi:10.1046/j.1439-0272.2000.00324.x
更新日期:2000-03-01 00:00:00
abstract::Our laboratory has previously reported significantly low levels of protamine (PRM) gene expression in infertile men. This drop was correlated with a low pregnancy rate, suggesting that PRMs may be useful as predictive factors for the outcome of testicular sperm extraction and intracytoplasmic sperm injection (TESE-ICS...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2007.00775.x
更新日期:2007-08-01 00:00:00
abstract::Multiple morphological abnormalities of the sperm flagella (MMAF) is a rare disease associated with male infertility. In our previous study, we identified a homozygous CFAP43 splice-site variant, c.3661-2delA, in a patient with MMAF. However, the mutational effect of this variant was unknown. Here, using a minigene as...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13575
更新日期:2020-07-01 00:00:00
abstract::The cooperation in cases of childlessness between andrologists and gynecologists is an essential of any treatment. In a short communication it was shown that a special investigation form can be helpful for reciprocal information. This investigation form improves the information rate form 10% to 30%. In some cases the ...
journal_title:Andrologia
pub_type: 杂志文章
doi:
更新日期:1987-11-01 00:00:00
abstract::The aim of this study was to find discriminatory parameters, based on sperm characteristics on the day of ovum pickup, that can help guide the decision to perform either intracytoplasmic sperm injection (ICSI) or in vitro fertilisation (IVF). We evaluated 112 cycles fertilised with both regular and ICSI insemination d...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2010.01107.x
更新日期:2012-04-01 00:00:00
abstract::Erectile dysfunction (ED) is usually associated with cardiovascular disease and reduced endothelial function. The aim of the present study was to examine the effect of tadalafil and statin on the endothelial function of cavernous and brachial arteries in healthy men and in patients with ED. The cases included in the s...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12153
更新日期:2014-09-01 00:00:00
abstract::To assess the protective effects of Eugenia jambolana extract (EJE) or N-acetyl cysteine (NAC) on testis, cisplatin (CIS, 5 mg kg(-1) bw, single dose) was administered either alone or along with EJE (25 mg kg(-1) bw, alternate day) or NAC (150 mg kg(-1) bw, Day 1 and 4) for 7 days. Significant alterations in serum LH,...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12247
更新日期:2015-03-01 00:00:00
abstract::The level of fructose, NEFA, triglycerides and lipase activity were determined in the semen of 17 normozoospermic, 10 oligozoospermic and 10 azoospermic men. This was done immediately and 2 hours after seminal liquefaction. The levels of fructose and NEFA were significantly decreased while triglycerides show significa...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1983.tb00372.x
更新日期:1983-05-01 00:00:00
abstract::In a controlled double blind trial the effectiveness and tolerability of Kallikrein in patients suffering from astheno-oligozoospermia was examined in comparison to placebo. 30 patients with astheno-oligozoospermia of idiopathic origin entered the study; they were subdivided into two homogeneous groups of 15 patients ...
journal_title:Andrologia
pub_type: 临床试验,杂志文章
doi:10.1111/j.1439-0272.1984.tb00256.x
更新日期:1984-03-01 00:00:00