Adverse effects of leptin on histone-to-protamine transition during spermatogenesis are prevented by melatonin in Sprague-Dawley rats.

abstract：:Sildenafil citrate is a selective phosphodiesterase 5 (PDE-5) inhibitor and partial phosphodiesterase 6 inhibitor prescribed for erectile dysfunction. Post-marketing case reports of nonarteritic anterior ischaemic optic neuropathy (NAION) over the past few years suggest a potential link with PDE-5 inhibitors. We repor...

journal_title：Andrologia

authors： El-Domyati MM,El-Fakahany HM,Morad KE

更新日期：2009-10-01 00:00:00

abstract：:Progressive Motility Sustaining Factor (PMSF) was isolated from human epididymides. PMSF could significantly improve progressive motility of oligozoospermic as well as asthenozoospermic semen. PMSF was found to increase cyclic AMP accumulation by the human spermatozoa indicating its possible mode of action. ...

journal_title：Andrologia

authors： Sheth AR,Gunjikar AN,Shah GV

更新日期：1981-03-01 00:00:00

abstract：:This prospective-cohort study aimed at investigating the influence of paternal lifestyle factors on semen parameters and intracytoplasmic sperm injection (ICSI) outcomes. The influence of paternal lifestyle factors on seminal quality and ICSI outcomes was investigated in male patients undergoing conventional semen ana...

journal_title：Andrologia

authors： Borges E Jr,Braga DPAF,Provenza RR,Figueira RCS,Iaconelli A Jr,Setti AS

更新日期：2018-11-01 00:00:00

abstract：:Several substances can interfere with microtubular function eg. colchicine. Melatonin, a hormone secreted by the pineal gland has similar effects as colchicine on microtubules. In this study melatonin levels were determined in both plasma and seminal plasma of patients with good or impaired motility and forward progre...

journal_title：Andrologia

authors： Bornman MS,Oosthuizen JM,Barnard HC,Schulenburg GW,Boomker D,Reif S

更新日期：1989-09-01 00:00:00

abstract：:The aim of this study was to evaluate the effect of Lepidium meyenii (maca) in chemically and physically subfertile mice. After 35 days, the following groups of mice were evaluated: control, sham, chemical subfertility, chemical subfertility-maca-supplemented, physical subfertility, physical subfertility-maca-suppleme...

journal_title：Andrologia

authors： Valdivia Cuya M,Yarasca De La Vega K,Lévano Sánchez G,Vásquez Cavero J,Temoche García H,Torres Torres L,Cruz Ornetta V

更新日期：2016-10-01 00:00:00

abstract：:Epidermal growth factor concentrations and amounts per ejaculate were determined in 162 infertile men and in a control group of 50 pregnancy-proven fertile men. No differences were found between those groups. The group of infertile patients was divided into sub-groups according to their sperm density. EGF values in th...

journal_title：Andrologia

authors： Delgado SR,Ramirez K,Mallea E

更新日期：1991-05-01 00:00:00

abstract：:Pfaffia glomerata (Spreng.) Pedersen, popularly known as "Brazilian ginseng," is used as medicinal plant in Brazil to treat inflammatory diseases in general. Previous studies showed that its extract increases the nitric oxide (NO) levels. Knowing that NO downregulates steroidogenesis and that alterations in the action...

journal_title：Andrologia

authors： Auharek SA,Carollo CA,Oliveira RJ,Cunha-Laura AL,Monreal ACD,Siqueira JM,Costa DS,de Paiva Condé TR,Wollf DIL,Aloysio Amaral E

更新日期：2019-09-01 00:00:00

abstract：:Varicocele is one of causes of the declined sperm quality and low sperm production, which can lead to infertility in males. There are several experimental and epidemiological findings which support the idea that inflammatory mechanisms play an essential role in varicocele pathogenesis. Besides, in this pathological st...

journal_title：Andrologia

authors： Zeinali M,Hadian Amree A,Khorramdelazad H,Karami H,Abedinzadeh M

更新日期：2017-08-01 00:00:00

abstract：:The role of opioidergic system in controlling gonadotropin secretion in elderly men still remains uncertain. In the present study, we attempted to examine the opioidergic inhibitory tone imposed on GnRH release mechanism in elderly men by monitoring the plasma gonadotropin response to the opiate receptor antagonist na...

journal_title：Andrologia

authors： Mikuma N,Kumamoto Y,Maruta H,Nitta T

更新日期：1994-01-01 00:00:00

abstract：:A 45-year-old male with azoospermia was presented to us with primary infertility. We found that he had been taking testosterone due to erectile dysfunction. Upon its discontinuation, the normozoospermia was restored. This led to a pregnancy. In men aged 40-50, the diagnostic work up of testosterone deficiency should b...

journal_title：Andrologia

authors： Jan Z,Pfeifer M,Zorn B

更新日期：2012-05-01 00:00:00

abstract：:Subnormal levels of testosterone are associated with significant negative health consequences, with higher risks of all-cause and cardiovascular mortality. The numbers of studies reporting on the benefits of normalisation of testosterone is increasing but longer-term data on (elderly) men receiving testosterone treatm...

journal_title：Andrologia

authors： Yassin AA,Nettleship J,Almehmadi Y,Salman M,Saad F

更新日期：2016-09-01 00:00:00

abstract：:Idiopathic oligoathenoteratozoospermia (iOAT) is a common finding in the evaluation of male infertility. Oxidative stress (OS) may underlie its pathology. Tamoxifen and l-carnitine are used to treat idiopathic male infertility. The aim of this work was to detect the efficacy of tamoxifen and l-carnitine on sperm param...

journal_title：Andrologia

authors： Nada EA,El Taieb MA,Ibrahim HM,Al Saied AE

更新日期：2015-09-01 00:00:00

abstract：:The aim of this study was to investigate the predictive value of the parameters that might have an effect on the success of microscopic testicular sperm extraction (micro-TESE) in infertile patients with nonobstructive azoospermia (NOA). Between 2003 and 2014, 860 patients with NOA were retrospectively analysed. The e...

journal_title：Andrologia

authors： Kizilkan Y,Toksoz S,Turunc T,Ozkardes H

更新日期：2019-12-01 00:00:00

abstract：:Little is known about the biological and clinical significance of bilaterally enlarged testes (bilateral megalotestes or macroorchidism). We have investigated clinical, endocrine and spermatological characteristics of 135 andrological patients with a testicular volume of more than 25 ml bilaterally. 135 patients with ...

journal_title：Andrologia

authors： Meschede D,Behre HM,Nieschlag E

更新日期：1995-07-01 00:00:00

abstract：:Exposure of intact rats to increasing doses of oestradiol-17 beta in the presence of a constant amount of exogenous androgen caused a dose-related increase in the concentration of zinc in the lateral lobes and a decrease in the levels of ventral lobe prolactin binding. These changes occurred concomitantly with a dose-...

journal_title：Andrologia

authors： Oldereid NB,Thomassen Y,Rui H,Gordeladze JO,Haug E,Purvis K

更新日期：1986-09-01 00:00:00

abstract：:Sirolimus is used as a powerful immunosuppressant drug in patients after organ transplantation. It was shown to block spermatogenesis by interrupting the stem cell factor/c-kit system. Oligozoospermia was shown in single patients. In addition, a decrease of testosterone and an increase of gonadotropin levels were obse...

journal_title：Andrologia

authors： Skrzypek J,Krause W

更新日期：2007-10-01 00:00:00

abstract：:Mesterolone, HCG and PMS, clomiphene and various other drugs were administered to 236 subfertile patients with disturbed spermatogenesis. Most of the patients received mesterolone. The effects of the various therapeutic regimes are discussed. Improvement of the sperm count and spermatozoal motility was more frequent a...

journal_title：Andrologia

authors： Ibrahim A,Hayat ZG

更新日期：1983-01-01 00:00:00

abstract：:The incretory testicular function was tested in 21 patient with varicocele aged 19 to 39 years. In one group baseline testosterone was measured, while a second group received a single injection of 5000 IU HCG. Testosterone was studied in peripheral plasma in the spermatic vein and in testicular tissue. Baseline values...

journal_title：Andrologia

authors： Pirke KM,Vogt HJ,Sintermann R,Spyra B

更新日期：1983-11-01 00:00:00

abstract：:Cryptorchidism is the most common congenital anomaly in male children. Its aetiology remains unknown in the majority of cases. Because HOXA11 plays a vital role in regulating testicular descent, genetic variants in HOXA11 genes may contribute to the risk of cryptorchidism. In this study, mutation analysis was performe...

journal_title：Andrologia

authors： Lu P,Wang Y,Wang F,Huang J,Zeng Y,He D,Huang H,Cheng Z

更新日期：2018-02-01 00:00:00

abstract：:Gamma-glutamyl transpeptidase was purified to apparent homogeneity from human testis by DEAE cellulose, acetone, precipitation, fractionation by ammonium sulphate, Sephacryl S-200 chromatography, Q-Sepharose chromatography and S-Sepharose chromatography following solubilization of the enzyme by Triton X-100. The purif...

journal_title：Andrologia

authors： Yoshida K,Arai K,Kobayashi N,Saitoh H

更新日期：1990-05-01 00:00:00

abstract：:This investigation was carried out to study the correlation of sperm quality parameters with antioxidant and oxidant status of buffalo bull semen during various stages of cryopreservation. Semen samples were evaluated for sperm parameters (mass motility [MM], concentration [CON], progressive motility [PM], viability [...

journal_title：Andrologia

authors： Lone SA,Prasad JK,Ghosh SK,Das GK,Balamurugan B,Verma MR

更新日期：2018-02-11 00:00:00

abstract：:Spermatozoa of six men with normozoospermia, oligozoospermia and teratozoospermia were capacitated in vitro in modified Tyrode's medium und evaluated for acrosome reaction using the recently described triple-stain technique. The resulting kinetics illustrate the different capacitation behaviour and ability of spermato...

journal_title：Andrologia

authors： Töpfer-Petersen E,Heissler E,Schill WB

更新日期：1985-05-01 00:00:00

abstract：:This study aimed to examine the association of herpes zoster (HZ) with androgen deprivation therapy (ADT) use among patients with prostate cancer (PC), using a population-based data set. The study sample for this study was retrieved from the Taiwan Longitudinal Health Insurance Database 2005. We selected 877 patients ...

journal_title：Andrologia

authors： Wu FJ,Kao LT,Sheu SY,Lin HC,Chung SD

更新日期：2018-03-01 00:00:00

abstract：:Research has revealed that reactive oxygen species (ROS) negatively affect sperm function, both in vivo and in vitro. Sperm preparation techniques for assisted reproductive technologies (ART) are potential causes for additional ROS production. This study aimed to correlate the concentration of exogenous H(2)O(2) with ...

journal_title：Andrologia

authors： du Plessis SS,McAllister DA,Luu A,Savia J,Agarwal A,Lampiao F

更新日期：2010-06-01 00:00:00

abstract：:Human chorionic Gonadotropin (HCG) therapy has been used beneficially in men with subfertility especially after varicocele surgery. Very few side effects have been observed in male patients. Herein, we report a case of pulmonary embolism in a male patient following the use of HCG. The patient was subsequently found to...

journal_title：Andrologia

authors： Dhabuwala CB,Kumar A,Pierce JM

更新日期：1987-01-01 00:00:00

abstract：:This study was aimed at determining the effects of corn and wheat gluten, used as dietary protein sources, on live weight gain, sperm quality and the histology of the testes and accessory glands in male rats. For this purpose, 20-day-old 24 male Wistar albino rats were randomly assigned to three groups. Group 1 (Contr...

journal_title：Andrologia

authors： Gumus R,Uslu S,Uslu BA

更新日期：2020-07-01 00:00:00

abstract：:Elevated platelet levels have been postulated to be associated with cardiovascular diseases, conditions closely linked to erectile dysfunction (ED). The current systematic review and meta-analysis was performed to assess the platelet indices, which including platelet count (PLT), mean platelet volume (MPV) and platele...

journal_title：Andrologia

authors： Yang G,Muzepper M

更新日期：2019-06-01 00:00:00

abstract：:The aim of this study was to comprise the effect of catalase on sperm parameters and chromatin in normospermic persons. Semen samples were obtained from fertile men. A certain amount of different concentrations of catalase (0.1, 1, 10, 50, 100, 150 and 200 IU.ml) was added to each vial containing semen. Control group ...

journal_title：Andrologia

authors： Mohammadzadeh M,Ramazani V,Khalili MA,Hamishekar H,Dehghan Marvast L,Talebi AR,Zare-Zardini H,Ghasemi S

更新日期：2019-05-01 00:00:00

abstract：:Ten subfertile men affected by idiopathic oligoteratoasthenozoospermia and exhibiting normal serum hormone levels received a long-term treatment with human pure follicle-stimulating hormone (hp-FSH) (150 IU, intramuscularly, three times per week for 6 months). Semen parameters and ultrastructural features of spermatoz...

journal_title：Andrologia

authors： Arnaldi G,Balercia G,Barbatelli G,Mantero F

更新日期：2000-05-01 00:00:00

abstract：:Using a highly sensitive radioimmunoassay (RIA) of estramustine binding protein (EMBP) with the antibody raised against rat-EMBP, the concentration of EMBP in human benign prostatic hypertrophy (BPH) tissue was evaluated. Using mechanical separation procedure, EMBP was found significantly higher in the epithelium (10....

journal_title：Andrologia

authors： Shiina H,Mizutani M,Ishibe T

更新日期：1990-07-01 00:00:00