Disordered APC/C-mediated cell cycle progression and IGF1/PI3K/AKT signalling are the potential basis of Sertoli cell-only syndrome.

abstract：:The role of N-methyl-D-aspartate (NMDA) and non-NMDA receptors in the control of FSH and LH secretion was analysed in prepubertal male rats. In the first experiment 4, 8, 12, 16, 20 and 30-day-old males were decapitated 15 min after vehicle, NMDA or kainic acid (KA) administration. In the second experiment, 23-day-old...

journal_title：Andrologia

authors： Aguilar E,Tena-Sempere M,Gonzalez D,Pinilla L

更新日期：1996-05-01 00:00:00

abstract：:Sirolimus is used as a powerful immunosuppressant drug in patients after organ transplantation. It was shown to block spermatogenesis by interrupting the stem cell factor/c-kit system. Oligozoospermia was shown in single patients. In addition, a decrease of testosterone and an increase of gonadotropin levels were obse...

journal_title：Andrologia

authors： Skrzypek J,Krause W

更新日期：2007-10-01 00:00:00

abstract：:The sperm motile efficiency (SME) of fresh spermatozoa in a hypotonic medium was investigated concerning the prediction of post thaw motility and the differentiation between fertile men and infertility patients. A total of 95 semen samples were collected for this study. Twenty of these samples were obtained from semen...

journal_title：Andrologia

authors： Glander HJ,Bock H,Winiecki P

更新日期：1989-07-01 00:00:00

abstract：:For studies addressing the functions of Leydig cells, isolated cells are often better suited than intact animals. Here, the isolation procedure of Leydig cells from adult male Djungarian hamsters (Phodopus sungorus) is described. Cells were isolated using a procedure involving enzymatic dissociation and Percoll-gradie...

journal_title：Andrologia

authors： Niedziela M,Lerchl A

更新日期：1999-05-01 00:00:00

abstract：:The scope of this study was to evaluate the accuracy, precision and specificity of the sperm concentration measurements by the Strömberg-Mika Cell Motion Analyser (SM-CMA). Our data show that the instrument generally underscores the sperm concentration and therefore the uncorrected measurements must be corrected by th...

journal_title：Andrologia

authors： Togni G,Gallicciotti G,Coccia P,Piffaretti-Yanez A,Stamm J,Balerna M

更新日期：1995-01-01 00:00:00

abstract：:The reference values of human semen, published in the WHO's latest edition in 2010, were lower than those previously reported. The objective of this study was to evaluate reference values of standard semen parameters in fertile Egyptian men. This cross-sectional study included 240 fertile men. Men were considered fert...

journal_title：Andrologia

authors： Zedan H,Ismail S,Gomaa A,Saleh R,Henkel R,Agarwal A

更新日期：2018-01-15 00:00:00

abstract：:Statins are lipid-lowering medications widely used to reduce the risk of cardiovascular diseases. Biochemically, they act by decreasing synthesis of cholesterol via inhibiting 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase. Since 1992, various research studies have investigated the effect of statins on semen quality...

journal_title：Andrologia

authors： Banihani SA

更新日期：2020-07-01 00:00:00

abstract：:Male infertility is a major health problem worldwide. We investigated a possible association between leptin, obesity, hormonal interplay and male infertility. This cross-sectional study of 313 males (178 infertile and 135 fertile) was carried out in 2017. The subjects were categorised by body mass index (BMI) and body...

journal_title：Andrologia

authors： Amjad S,Baig M,Zahid N,Tariq S,Rehman R

更新日期：2019-02-01 00:00:00

abstract：:Alkaline (ALP) and acid (ACP) phosphomonoesterases present in the cell-free extracts of the Triton x-100 treated freshly ejaculated chicken spermatozoa were studied of some of their physico-chemical properties. Alkaline phosphomonoesterase was found to have the optimal specific activity at pH 7.6 in 100 mM Tris-HCl bu...

journal_title：Andrologia

authors： Mohan J,Panda JN,Singh US

更新日期：1989-01-01 00:00:00

abstract：:The routine spermiogram parameters of 3432 patients born between 1952 and 1971 in the region of Leipzig were determined between January 1975 and March 2000. The patient group aged 24-35 years was characterized by low mobility and relocation living in the main centre of chemical industry with enormous environmental pol...

journal_title：Andrologia

authors： Paasch U,Thieme C,Glander HJ

更新日期：2003-12-01 00:00:00

abstract：:This study was set to determine if there is a correlation between the general toxic effect and the gonadotoxic effect of DBCP on male rats. Groups of male rats were injected with a single dose of DBCP (50 mg kg-1) dissolved in dimethylsulfoxide (DMSO). Twenty four hours, one and four weeks post injection animals were ...

journal_title：Andrologia

authors： Kaplanski J,Shemi D,Waksman J,Potashnik G,Sod-Moriah UA

更新日期：1991-09-01 00:00:00

abstract：:Our previous study found that Chinese chive could significantly (p < 0.01) raise testosterone and nitric oxide (NO) levels in mice serum. However, the specific functional components of this traditional remedy are still unknown. In order to isolate and identify the active constituents from Chinese chive for enhancing t...

journal_title：Andrologia

authors： Gu S,Wang X,Zhou R,Huang J

更新日期：2019-03-01 00:00:00

abstract：:Open and double-blind therapeutic studies were carried out on the effects of tamoxifen in oligozoospermia. The examinations involved 74 patients. The first group (n = 20) received tamoxifen 20 mg/day; the second group (n = 54) got tamoxifen or placebo for 3 months. In the open study, tamoxifen treatment led to signifi...

journal_title：Andrologia

authors： Török L

更新日期：1985-09-01 00:00:00

abstract：:This short review summarizes some recent findings on arylhydrocarbon (dioxin) receptor expression during early pregnancy in mammals. The arylhydrocarbon receptor is a ligand-activated transcription factor and was originally described as a mediator of the toxic effects of dioxins and other chlorinated hydrocarbons such...

journal_title：Andrologia

authors： Fischer B

更新日期：2000-09-01 00:00:00

abstract：:To further investigate the effectiveness of pentoxifylline (trental) treatment in male infertility, we studied 22 young men (mean age 28.4 years) with "idiopathic" oligo-asthenozoospermia treated for 6 months with the drug (1200 mg daily orally). Sperm concentration and sperm motility were determined before therapy, a...

journal_title：Andrologia

authors： Marrama P,Baraghini GF,Carani C,Celani MF,Giovenco P,Grandi F,Montanini V

更新日期：1985-11-01 00:00:00

abstract：:Human chorionic Gonadotropin (HCG) therapy has been used beneficially in men with subfertility especially after varicocele surgery. Very few side effects have been observed in male patients. Herein, we report a case of pulmonary embolism in a male patient following the use of HCG. The patient was subsequently found to...

journal_title：Andrologia

authors： Dhabuwala CB,Kumar A,Pierce JM

更新日期：1987-01-01 00:00:00

abstract：:Some cases of testicular trauma cause infertility especially when the injured testes are not removed. However, only a few long-term follow-up studies investigating endocrinological and semen parameters in patients who had testicular trauma have been conducted. Herein, we report an interesting case of a patient who spo...

journal_title：Andrologia

authors： Hagiuda J,Ishikawa H,Hanawa Y,Marumo K

更新日期：2014-05-01 00:00:00

abstract：:Nerve growth factor (NGF), which is required for the survival and differentiation of the nervous system, has been proved to play important roles in male reproductive physiology. Several studies have focused on the roles of NGF in the testes. However, no study has reported on the mechanism of paracrine and autocrine ac...

journal_title：Andrologia

authors： Jiang YW,Zhao Y,Chen SX,Chen L,Li CJ,Zhou X

更新日期：2018-02-01 00:00:00

abstract：:Penile amputation is an uncommon condition for which immediate surgical replantation is warranted. This work aimed to represent intervention and management for an amputated penis by replantation and reconstruction. A 23-year-old man presented with traumatic penile amputation for 2 h where the penile proximal part was ...

journal_title：Andrologia

authors： Salem HK,Mostafa T

更新日期：2009-08-01 00:00:00

abstract：:Testicular tissue and sex hormones are sensitive to the anabolic steroids (oxymetholone/OM) due to increased free radical damage and hormonal changes. The Nasturtium officinale L. have various antioxidant compounds. The aim of the present study was to investigate N. officinale effect on OM-induced oxidative injury in ...

journal_title：Andrologia

authors： Akbari Bazm M,Khazaei M,Khazaei F,Naseri L

更新日期：2019-08-01 00:00:00

abstract：:Azoospermia factor (AZF) genes on the long arm of the human Y chromosome are involved in spermatogenesis, and microdeletions in the AZF region have been recognised to be the second major genetic cause of spermatogenetic failure resulting in male infertility. While screening for these microdeletions can avoid unnecessa...

journal_title：Andrologia

authors： Zhu XB,Gong YH,He J,Guo AL,Zhi EL,Yao JE,Zhu BS,Zhang AJ,Li Z

更新日期：2017-06-01 00:00:00

abstract：:Little is known about the biological and clinical significance of bilaterally enlarged testes (bilateral megalotestes or macroorchidism). We have investigated clinical, endocrine and spermatological characteristics of 135 andrological patients with a testicular volume of more than 25 ml bilaterally. 135 patients with ...

journal_title：Andrologia

authors： Meschede D,Behre HM,Nieschlag E

更新日期：1995-07-01 00:00:00

abstract：:The calcium-binding proteins (CBPs) of mouse epididymal spermatozoa were analysed by mobility changes in the presence of added Ca2+ in two-dimensional sodium dodecyl sulphate-polyacrylamide gel electrophoresis (SDS-PAGE). The expression patterns of relatively high molecular weight CBPs (Mr > 20 kDa) were different bet...

journal_title：Andrologia

authors： Gye MC,Park S,Kim YS,Ahn HS

更新日期：2001-07-01 00:00:00

abstract：:Recent studies have revealed a high prevalence of leukocytospermia (> 1 x 10(6) white blood cells ml-1 semen) in male infertility patients in the USA and certain European countries, and have implicated white blood cells as a cause of infertility. Since leukocytospermia may often be attributed to male genital-tract inf...

journal_title：Andrologia

authors： Wang AW,Politch J,Anderson D

更新日期：1994-05-01 00:00:00

abstract：:Gynaecomastia, the enlargement of the male breast, is considered as an andrological disease. To date, a review on male breast cancer (MBC) has not been published in an andrological journal. The papers underlying this review were published from authors of different institutions: Clinical Genetics, Dermatology, Gynaecol...

journal_title：Andrologia

authors： Krause W

更新日期：2004-12-01 00:00:00

abstract：:The aim of the study was to characterise the alterations in expression of some apoptosis regulators in unilaterally and bilaterally heat-treated mouse testes at different time intervals to 42 days after surgery. Cryptorchidism was induced in immature mice by returning the testis to the abdominal cavity via a surgical ...

journal_title：Andrologia

authors： Absalan F,Movahedin M,Mowla SJ

更新日期：2010-02-01 00:00:00

abstract：:Efficacy and safety of testosterone gel 2% (TG) were evaluated in two phase 3, open-labelled, single-arm, multicentre studies (000023 and extension study 000077). Hypogonadal men having serum testosterone levels <300 ng/dl at two consecutive measurements were included. Study duration was 9 months (000023: 3 months; 00...

journal_title：Andrologia

authors： Belkoff L,Brock G,Carrara D,Neijber A,Ando M,Mitchel J

更新日期：2018-02-01 00:00:00

abstract：:Sperm investigations of 35 epileptics being treated with hydantoin for a period of more than three years have shown that by a large dispersion of evaluations only 52% of the sperm cells were intact (teratozoospermia; compared with a normal limit of 60% p = 5%, of 70% p = 1%). The mobility of the sperm cells was 49% (a...

journal_title：Andrologia

authors： Schramm P,Seyfeddinipur N

更新日期：1980-01-01 00:00:00

abstract：:Parameters were obtained from the reproductive organs of ethanol-fed, gossypol-treated Sprague Dawley rats. The experimental animals were fed either on a normal (15.17%) or low protein (8.00%) diet. Measurements included reproductive organ weights, seminal characteristics, serum concentration of testosterone and histo...

journal_title：Andrologia

authors： Akingbemi BT,Rao PV,Aire TA

更新日期：1997-07-01 00:00:00

abstract：:The reduction of sperm motility and subsequently reduced ability to undergo capacitation and acrosome reaction are considered as common causes of male infertility. The β-defensin family is a group of well-known secretory proteins with antimicrobial activity that contribute to the process of "sperm maturation" during t...

journal_title：Andrologia

authors： Khayamabed R,Tavalaee M,Taherian SS,Nasr-Esfahani MH

更新日期：2020-02-01 00:00:00