Abstract:
:The aim of the study was to evaluate the sperm retrieval rate by microsurgical testicular sperm extraction (TESE) in familial idiopathic nonobstructive azoospermia (NOA). One hundred and nineteen patients with idiopathic NOA who underwent microsurgical TESE over the past 5 years were included. Patients were then divided into two groups; Group 'A' with familial idiopathic NOA (11 families with two brothers in each family, 22 patients) and Group 'B' with nonfamilial idiopathic NOA (97 patients). Clinical data as well as data of microsurgical TESE were recorded. In Group 'A', the sperm retrieval rate was 9.1% (2/22 patients) compared to 45.4% in Group 'B' (44/97 patients) (P ≤ 0.05). The two patients in Group 'A' with successful sperm retrieval belonged to one family. The histopathological diagnosis was the same in the brothers in each family. It can be concluded that the testicular sperm retrieval rate in familial idiopathic NOA is significantly lower than in nonfamilial idiopathic NOA.
journal_name
Andrologiajournal_title
Andrologiaauthors
Arafa MM,ElBardisi HT,AlSaid SS,Majzoub A,AlMalki AH,ElRobi I,AlAnsari AAdoi
10.1111/and.12378subject
Has Abstractpub_date
2015-11-01 00:00:00pages
1062-7issue
9eissn
0303-4569issn
1439-0272journal_volume
47pub_type
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