Outcome of microsurgical testicular sperm extraction in familial idiopathic nonobstructive azoospermia.

Abstract:

:The aim of the study was to evaluate the sperm retrieval rate by microsurgical testicular sperm extraction (TESE) in familial idiopathic nonobstructive azoospermia (NOA). One hundred and nineteen patients with idiopathic NOA who underwent microsurgical TESE over the past 5 years were included. Patients were then divided into two groups; Group 'A' with familial idiopathic NOA (11 families with two brothers in each family, 22 patients) and Group 'B' with nonfamilial idiopathic NOA (97 patients). Clinical data as well as data of microsurgical TESE were recorded. In Group 'A', the sperm retrieval rate was 9.1% (2/22 patients) compared to 45.4% in Group 'B' (44/97 patients) (P ≤ 0.05). The two patients in Group 'A' with successful sperm retrieval belonged to one family. The histopathological diagnosis was the same in the brothers in each family. It can be concluded that the testicular sperm retrieval rate in familial idiopathic NOA is significantly lower than in nonfamilial idiopathic NOA.

journal_name

Andrologia

journal_title

Andrologia

authors

Arafa MM,ElBardisi HT,AlSaid SS,Majzoub A,AlMalki AH,ElRobi I,AlAnsari AA

doi

10.1111/and.12378

subject

Has Abstract

pub_date

2015-11-01 00:00:00

pages

1062-7

issue

9

eissn

0303-4569

issn

1439-0272

journal_volume

47

pub_type

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