Functional characterisation of a natural androgen receptor missense mutation (N771H) causing human androgen insensitivity syndrome.

abstract：:The techniques of SDS-polyacrylamide slab gel electrophoresis and a sensitive fluorescamine-based method were used to study autoproteolysis of human seminal coagulum at various pH. The major protein bands of 72 and 55 Kd were optimally degraded at pH 7.5. Degradation at pH 3.5 was preceded by a lag period of 30 min. W...

journal_title：Andrologia

authors： Boonsaeng V

更新日期：1986-05-01 00:00:00

abstract：:We examined whether men with anabolic-steroid-induced hypogonadism (ASIH) seeking testosterone supplementation therapy (TST) regretted their decision to use anabolic-androgenic steroids (AAS) and what their reasons were for this regret. An anonymous, prospective survey was distributed to 382 men seeking follow-up trea...

journal_title：Andrologia

authors： Kovac JR,Scovell J,Ramasamy R,Rajanahally S,Coward RM,Smith RP,Lipshultz LI

更新日期：2015-10-01 00:00:00

abstract：:Testicular dysfunction or damage is among the critical side effects of chemotherapeutic drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of eugenol on cisplatin-induced testicular damage. In this experimental study, a single dose of cisplatin (15 mg/kg) was given intraperitonea...

journal_title：Andrologia

authors： Ekinci Akdemir FN,Yildirim S,Kandemir FM,Aksu EH,Guler MC,Kiziltunc Ozmen H,Kucukler S,Eser G

更新日期：2019-10-01 00:00:00

abstract：:Sperm DNA integrity is important for normal functions such as fertilization, implantation, pregnancy and fetal development. Sperm DNA fragmentation (SDF) is more common in infertile men and may be responsible for poor reproductive function. Although there are a number of tests available to measure SDF, the terminal de...

journal_title：Andrologia

authors： Sharma R,Iovine C,Agarwal A,Henkel R

更新日期：2020-07-24 00:00:00

abstract：:In order to investigate whether a hypothalamic disorder cause hypogonadism in male prolactinomas, LH pulsatile secretion was studied in 13 male patients. Serum PRL levels ranged from 186 to 45,000 ng ml-1 before treatment, and all the tumors were macroadenomas. Reduced LH secretion was revealed in 5 of 13 patients, an...

journal_title：Andrologia

authors： Saitoh Y,Arita N,Hayakawa T,Onishi T,Koga M,Mori S,Mogami H

更新日期：1990-11-01 00:00:00

abstract：:Two esterases previously identified in seminal plasma, on the basis of their electrophoretic mobility, immunogenicity and sensitivity to organophosphorus esters were detected in various human external secretions and leucocyte extracts. alpha-Esterase was found to be abundant in urine and milk whereas this enzyme occur...

journal_title：Andrologia

authors： Roberts TK,Masson PL,Lauwerys R,Heremans JF

更新日期：1976-01-01 00:00:00

abstract：:In the present study, our experience in the collection of semen from adult bonnet monkeys and some of the characteristics of semen are reported. Semen samples were collected by penile stimulation every 15 days over a period of 3 years. The penile method of ejaculation was more consistent with an increased volume of se...

journal_title：Andrologia

authors： Ramesh V,Ramachandra SG,Krishnamurthy HN,Rao AJ

更新日期：1998-03-01 00:00:00

abstract：:The manual of the World Health Organization defines leucocytospermia as the presence of >1 x 10(6) white blood cells per ml semen. Most authors consider leucocytospermia to be a consequence of inflammation due to bacterial infection. However, the efficacy of antibiotic therapy was not unequivocally demonstrated until ...

journal_title：Andrologia

authors： Krisp A,Hörster S,Skrzypek J,Krause W

更新日期：2003-08-01 00:00:00

abstract：:The total amount of humoral sperm antibody protein is determined following its isolation by affinity-chromatography on spermatozoa. Serum proteins are eluted by Sorensen phosphate buffer. Antibodies attached to spermatozoa suspended in Sephadex G 75 columns resist elution by Sorensen buffer. They can be quantitatively...

journal_title：Andrologia

authors： Gradl T,Mettler L,Schirren C

更新日期：1975-01-01 00:00:00

abstract：:By means of a recently developed apparatus ("Separon") motile spermatozoa were concentrated in a small volume of culture medium (0,3 ml). Sperm concentration, progressive motility and mean velocity of 60 ejaculates were determined by a computerized videomicrography system. After "Separon" sperm concentration was reduc...

journal_title：Andrologia

authors： Wölbling RH,Pemper B,Möslein S,Milbradt R,Taubert HD

更新日期：1988-01-01 00:00:00

abstract：:The effects of vasectomy on seminal viscosity, volume and pH have been investigated in freshly emitted semen of 21 healthy men before operation and three months later. Viscosity and the pH range were decreased significantly, but the decrease of the seminal volume was not significant. Reasons of changes have been discu...

journal_title：Andrologia

authors： Nikkanen V

更新日期：1979-03-01 00:00:00

abstract：:Conventional sperm freezing methods perform best when freezing sperm samples containing at least hundreds of spermatozoa. In this severe male factor infertility case series, we examined the reproductive outcomes in 12 intracytoplasmic sperm injection cases where spermatozoa used were frozen in Cell Sleepers. Cell Slee...

journal_title：Andrologia

authors： Coetzee K,Ozgur K,Berkkanoglu M,Bulut H,Isikli A

更新日期：2016-03-01 00:00:00

abstract：:The aim of this study was to analyse the impact of assistance on the comprehensibility and reliability of the Turkish version of International Index of Erectile Function (IIEF). In this study, 458 patients were asked to complete the IIEF questionnaire by themselves during their first visit and then once again during t...

journal_title：Andrologia

authors： Bayraktar Z,Atun I

更新日期：2013-04-01 00:00:00

abstract：:Methylenetetrahydrofolate reductase (MTHFR), the key enzyme of the folate metabolic pathway, has been reported to be five times more active in the testicles compared to other organs in adult mice. The aim of this study was to investigate the relationship between MTHFR c.677C>T and c.1298A>C polymorphisms and infertili...

journal_title：Andrologia

authors： Gurkan H,Tozkır H,Göncü E,Ulusal S,Yazar M

更新日期：2015-11-01 00:00:00

abstract：:Altered protamine 1 (PRM1)/ protamine 2 (PRM2) mRNA ratio in testicular biopsy samples correlates with sperm quality and its fertilising ability. This study is planned to assess PRM1/ PRM2 mRNA ratio in subgroups of azoospermia to suggest a more reliable and accurate marker for assessing sperm quality in nonobstructiv...

journal_title：Andrologia

authors： Amjad S,Mushtaq S,Rehman R,Munir A,Zahid N,Siddique PQR

更新日期：2021-01-11 00:00:00

abstract：:The ZP3 protein is a zona pellucida glycoprotein which plays a major role in sperm binding and induction of the acrosome reaction. ZP3 proteins occur in various mammalian zonae pellucidae; their primary structures are highly conserved as revealed by cDNA cloning. We generated antisera against synthetic peptides that a...

journal_title：Andrologia

authors： Hinsch E,Hinsch KD

更新日期：1996-01-01 00:00:00

abstract：:Gamma-glutamyl transpeptidase was purified to apparent homogeneity from human testis by DEAE cellulose, acetone, precipitation, fractionation by ammonium sulphate, Sephacryl S-200 chromatography, Q-Sepharose chromatography and S-Sepharose chromatography following solubilization of the enzyme by Triton X-100. The purif...

journal_title：Andrologia

authors： Yoshida K,Arai K,Kobayashi N,Saitoh H

更新日期：1990-05-01 00:00:00

abstract：:Men with Down syndrome are considered as infertile although the causes of infertility are not known in detail yet. Although this constitutes a general rule there are three confirmed cases of parenting by fathers with Down syndrome. Many investigators have addressed the causes of infertility and their studies indicate ...

journal_title：Andrologia

authors： Stefanidis K,Belitsos P,Fotinos A,Makris N,Loutradis D,Antsaklis A

更新日期：2011-10-01 00:00:00

abstract：:The authors present the histological features of the testes in 1,609 cases of male sterility. In 485 cases (30.1%), histological changes were found, which did not warrant treatment. The histologic pattern of the testes was normal in only 39% of the cases of azoospermia; and only these patients were qualified for surge...

journal_title：Andrologia

authors： Janczewski Z,Bablok L

更新日期：1978-09-01 00:00:00

abstract：:The role of opioidergic system in controlling gonadotropin secretion in elderly men still remains uncertain. In the present study, we attempted to examine the opioidergic inhibitory tone imposed on GnRH release mechanism in elderly men by monitoring the plasma gonadotropin response to the opiate receptor antagonist na...

journal_title：Andrologia

authors： Mikuma N,Kumamoto Y,Maruta H,Nitta T

更新日期：1994-01-01 00:00:00

abstract：:Testicular torsion/detorsion induces oxidative/nitrosative stress, inflammation and apoptosis of testicular tissues. Baicalin exerts antioxidant and anti-inflammatory properties. This study investigated the possible protective effect of baicalin against testicular torsion-detorsion injury in rats. Surgical testicular ...

journal_title：Andrologia

authors： Fouad AA,Qutub HO,Jresat I

更新日期：2017-02-01 00:00:00

abstract：:Previous studies have confirmed that spermatogenesis in homozygous Immp2l mutant male mice was normal at the age of 6 months, but was significantly abnormal at the age of 13 months. Meanwhile, oxidative stress is reported to be involved in spermatogenic impairment in old mutant mice. However, it is unclear whether ant...

journal_title：Andrologia

authors： Jiang Y,Liu C,Lei B,Xu X,Lu B

更新日期：2018-03-01 00:00:00

abstract：:Twisting of the spermatic cord is considered a popular problem in the urological field, which may lead to testicular necrosis and male infertility. Sitagliptin, a glucose-lowering agent, proved to have a vindicatory function in myocardial and renal ischaemia/reperfusion (I/R), but its role in testicular I/R has not ye...

journal_title：Andrologia

authors： Abdel-Aziz AM,Naguib Abdel Hafez SM

更新日期：2020-03-01 00:00:00

abstract：:The events occurring at the maternal-foetal interface define a successful pregnancy but the current paradigm has shifted towards assessing the contribution of spermatozoa for embryogenesis. Spermatozoa with defective DNA integrity may fertilise the oocyte but affect subsequent embryonic development. The present case-c...

journal_title：Andrologia

authors： Dhawan V,Kumar M,Deka D,Malhotra N,Singh N,Dadhwal V,Dada R

更新日期：2019-02-01 00:00:00

abstract：:Air pollution constitutes the largest cause of environmental risks today. At present, no scientific publication linking environmental black soot and derangement in the hypothalamus and testis of rats exists. This study investigated the effect of black soot exposure on hypothalamic and testicular functions of male rats...

journal_title：Andrologia

authors： Onyeso G,Bohr EL,Nkpaa KW,Amadi PN,Ugwu AC

更新日期：2020-12-01 00:00:00

abstract：:Incidents of male infertility are mushrooming worldwide. Oxidative stress plays a prime role for its onset. Considering this background, the study was designed to focus the direct role of lycopene on cyproterone acetate (CPA) induced testicular hypofunction in rat. Four groups have been considered including the vehicl...

journal_title：Andrologia

authors： Tripathy A,Ara F,Ghosh P,Ghosh D

更新日期：2020-04-01 00:00:00

abstract：:During early development of the human testis the male germ cell first appears as primordial germ cell or gonocyte and enters the prospermatogonial stage after the twelfth week of gestation. Prospermatogonia lack glycogen particles and are connected by intercellular bridges. During the same period in the ovary the fema...

journal_title：Andrologia

authors： Wartenberg H

更新日期：1976-01-01 00:00:00

abstract：:Primary seminal vesicle adenocarcinoma is a rare malignancy of the male genito-urinary system with only a few confirmed reported cases. Initial tissue diagnostic modality is often a core biopsy specimen. Here, we report this rare entity in a 50-year-old male, highlighting the histomorphological and immunohistochemical...

journal_title：Andrologia

authors： Bhardwaj N,Rastogi P,Attri VS,Bora GS,Gorsi U

更新日期：2020-04-01 00:00:00

abstract：:One prerequisite for fertilization is the specific binding of spermatozoa to the zona pellucida. However, the factors and mechanisms involved in this gamete contact are not well understood. Gamete recognition and binding are species-specific and are controlled by oligosaccharides of the zona and their corresponding ca...

journal_title：Andrologia

authors： Michelmann HW,Töpfer-Petersen E,Schwartz P,Gratz G,Magerkurth C

更新日期：2001-09-01 00:00:00

abstract：:Autophagy is a pro-survival mechanism involving lysosomal degradation of damaged cellular components following multiple forms of cellular stress. There is currently a lack of literature on the mechanism, and specifically on mitophagy (selective autophagy of damaged pro-apoptotic mitochondria) in Sertoli cells (SCs). A...

journal_title：Andrologia

authors： Eid N,Kondo Y

更新日期：2018-02-01 00:00:00