Implications of prostate inflammation on male fertility.


:The prostate is the seat of three major causes of morbidity: benign prostatic hyperplasia, prostate cancer and prostatitis, three conditions in which inflammation has been implicated. A state of inflammation of the prostate gland, originally incited by an infection, an autoimmune response, a neurogenic stimulus or another trigger may have consequences on prostate functionality. In fact, male fertility depends intrinsically on the content of prostatic fluid factors secreted by the prostatic epithelium. Taking into account that the prostate gland is the major male accessory gland that exerts essential functions for male fertility, a state of local inflammation can alter male fertility by either directly impairing sperm quality or, indirectly, by causing prostate dysfunction. In the present review, we summarise the current knowledge regarding prostatitis due to well-known infections such as Escherichia coli, Chlamydia trachomatis and other commonly identified microorganisms focusing on inflammatory markers detected during these infections and seminal quality and male fertility alterations reported. We also focused on type III prostatitis or chronic nonbacterial prostatitis/chronic pelvic pain syndrome, of unknown aetiology, in which inflammation of an autoimmune origin, neurogenic stimuli or another trigger have been proposed and fertility alterations reported.






Motrich RD,Salazar FC,Breser ML,Mackern-Oberti JP,Godoy GJ,Olivera C,Paira DA,Rivero VE




Has Abstract


2018-12-01 00:00:00












  • The medical treatment of male infertility.

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    pub_type: 杂志文章


    authors: Ibrahim A,Hayat ZG

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    pub_type: 杂志文章,评审


    authors: Duca Y,Calogero AE,Cannarella R,Giacone F,Mongioi LM,Condorelli RA,La Vignera S

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    pub_type: 杂志文章


    authors: Timur H,Kokanali MK,Inal HA,Tuzluoglu D,Yilmaz N

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  • CAG Repeats in the androgen receptor gene is associated with oligozoospermia and teratozoospermia in infertile men in Jordan.

    abstract::CAG trinucleotide repeats are coded for the polyglutamine tract in the N-terminal of the androgen receptor (AR) gene which varies in normal individuals from 6 to 36 residues. In this study, we inspected the impact of the CAG repeats on the spermatogenic defects by measuring the size of AR-CAG repeats length in a cohor...


    pub_type: 杂志文章


    authors: Al Zoubi MS,Bataineh H,Rashed M,Al-Trad B,Aljabali AAA,Al-Zoubi RM,Al Hamad M,Issam AbuAlArjah M,Batiha O,Al-Batayneh KM

    更新日期:2020-10-01 00:00:00

  • The antiapoptotic and antioxidant effects of eugenol against cisplatin-induced testicular damage in the experimental model.

    abstract::Testicular dysfunction or damage is among the critical side effects of chemotherapeutic drugs like cisplatin. This study was mapped out to assess the possible therapeutic effect of eugenol on cisplatin-induced testicular damage. In this experimental study, a single dose of cisplatin (15 mg/kg) was given intraperitonea...


    pub_type: 杂志文章


    authors: Ekinci Akdemir FN,Yildirim S,Kandemir FM,Aksu EH,Guler MC,Kiziltunc Ozmen H,Kucukler S,Eser G

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  • The evaluation of free-L-carnitine, zinc and fructose in the seminal plasma of patients with varicocele and normozoospermia.

    abstract::The function of the epididymis and of the sex accessory glands have been investigated in a selected group of varicocele patients with normal sperm count. In the seminal plasma of these patients free-L-carnitine, fructose and zinc levels were determined as functional markers respectively of epididymis, seminal vesicles...


    pub_type: 杂志文章


    authors: Andó S,Carpino A,Buffone M,Maggiolini M,Sisci D

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    pub_type: 杂志文章


    authors: Kamal N,Agarwal AK,Jehan Q,Setty BS

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    pub_type: 杂志文章


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    pub_type: 杂志文章


    authors: Mangat HK

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    pub_type: 杂志文章


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    authors: Michelmann HW,Töpfer-Petersen E,Schwartz P,Gratz G,Magerkurth C

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    pub_type: 杂志文章


    authors: Sigg C,Hedinger C

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    pub_type: 杂志文章


    authors: Tripathy A,Ara F,Ghosh P,Ghosh D

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    pub_type: 杂志文章


    authors: Sanyal S,Patra PB,Nag S,Biswas NM

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    pub_type: 杂志文章


    authors: Gat Y,Gornish M,Chakraborty J,Perlow A,Levinger U,Pasqualotto F

    更新日期:2010-12-01 00:00:00

  • S100A7 is present in human sperm and a homologous pig sperm protein interacts with sperm-binding glycoprotein (SBG).

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    pub_type: 杂志文章


    authors: Teijeiro JM,Marini PE

    更新日期:2012-05-01 00:00:00

  • The treatment of male subfertility with kallikrein.

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    pub_type: 临床试验,杂志文章


    authors: Izzo PL,Canale D,Bianchi B,Meschini P,Esposito G,Menchini Fabris GF,Fasani R,Ohnmeiss H

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    pub_type: 杂志文章


    authors: Abou-Haila A,Fain-Maurel MA

    更新日期:1986-11-01 00:00:00

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    pub_type: 杂志文章


    authors: Gonzalez Buitrago JM,Garcia Diez LC

    更新日期:1982-01-01 00:00:00

  • Genetic analysis of HOXA11 gene in Chinese patients with cryptorchidism.

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    pub_type: 杂志文章


    authors: Lu P,Wang Y,Wang F,Huang J,Zeng Y,He D,Huang H,Cheng Z

    更新日期:2018-02-01 00:00:00