Abstract:
:The prostate is the seat of three major causes of morbidity: benign prostatic hyperplasia, prostate cancer and prostatitis, three conditions in which inflammation has been implicated. A state of inflammation of the prostate gland, originally incited by an infection, an autoimmune response, a neurogenic stimulus or another trigger may have consequences on prostate functionality. In fact, male fertility depends intrinsically on the content of prostatic fluid factors secreted by the prostatic epithelium. Taking into account that the prostate gland is the major male accessory gland that exerts essential functions for male fertility, a state of local inflammation can alter male fertility by either directly impairing sperm quality or, indirectly, by causing prostate dysfunction. In the present review, we summarise the current knowledge regarding prostatitis due to well-known infections such as Escherichia coli, Chlamydia trachomatis and other commonly identified microorganisms focusing on inflammatory markers detected during these infections and seminal quality and male fertility alterations reported. We also focused on type III prostatitis or chronic nonbacterial prostatitis/chronic pelvic pain syndrome, of unknown aetiology, in which inflammation of an autoimmune origin, neurogenic stimuli or another trigger have been proposed and fertility alterations reported.
journal_name
Andrologiajournal_title
Andrologiaauthors
Motrich RD,Salazar FC,Breser ML,Mackern-Oberti JP,Godoy GJ,Olivera C,Paira DA,Rivero VEdoi
10.1111/and.13093subject
Has Abstractpub_date
2018-12-01 00:00:00pages
e13093issue
11eissn
0303-4569issn
1439-0272journal_volume
50pub_type
杂志文章,评审相关文献
ANDROLOGIA文献大全abstract::There are no efficient and noninvasive clinical tests to distinguish between obstructive azoospermia (OA) and non-obstructive azoospermia (NOA). Epididymal protease inhibitor (Eppin) protein is secreted specifically by testes and epididymides in male reproductive system. It does not exist in seminal plasma of patients...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2011.01085.x
更新日期:2011-10-01 00:00:00
abstract::Sildenafil citrate is a selective phosphodiesterase 5 (PDE-5) inhibitor and partial phosphodiesterase 6 inhibitor prescribed for erectile dysfunction. Post-marketing case reports of nonarteritic anterior ischaemic optic neuropathy (NAION) over the past few years suggest a potential link with PDE-5 inhibitors. We repor...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2009.00933.x
更新日期:2009-10-01 00:00:00
abstract::Adult male bonnet monkeys maintained under regulated light: dark conditions exhibit a nycthemeral surge of testosterone. The present study attempts to determine the effect of administration of drugs that modulate prolactin levels like ergobromocriptine (EBC) and chlorpromazine (CPZ) on testosterone production. The inj...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1990.tb01975.x
更新日期:1990-05-01 00:00:00
abstract::Our aim was to establish the Estonian version of the National Institutes of Health chronic prostatitis symptom index (NIH-CPSI), and to examine its validity and applicability in chronic prostatitis patients as well as in community-based study. The questionnaire was tested in 54 category III prostatitis patients. In ad...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2006.00723.x
更新日期:2006-06-01 00:00:00
abstract::Fenitrothion (FNT) is a widely used organophosphorus pesticide in agriculture. Quercetin (QR), a plant-derived flavonoid, has a free radical scavenging property. This study investigated the protective effect of QR on FNT-induced testicular toxicity in rats. Twenty-four male rats were divided into four groups. Group I ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12467
更新日期:2016-06-01 00:00:00
abstract::Liquid nitrogen preservation in remote farms is a limitation. The goal of this study was to determine optimum temperature above freezing point for bovine spermatozoa preservation using bovine serum albumin (BSA) as a supplementation. Pooled semen sample from three ejaculates was subjected to various BSA concentration ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2011.01203.x
更新日期:2012-05-01 00:00:00
abstract::The aim of this study was to investigate the predictive value of the parameters that might have an effect on the success of microscopic testicular sperm extraction (micro-TESE) in infertile patients with nonobstructive azoospermia (NOA). Between 2003 and 2014, 860 patients with NOA were retrospectively analysed. The e...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13441
更新日期:2019-12-01 00:00:00
abstract::The objective of this study was to investigate the effect of ultra-rapid freezing (direct immersion in liquid nitrogen) on human spermatozoa in cryogenic vials (≥0.5 ml) at different concentrations of sucrose. After swim-up, the sperm suspensions (N = 58) were diluted with sperm preparation medium and divided into six...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12131
更新日期:2014-08-01 00:00:00
abstract::Incidents of male infertility are mushrooming worldwide. Oxidative stress plays a prime role for its onset. Considering this background, the study was designed to focus the direct role of lycopene on cyproterone acetate (CPA) induced testicular hypofunction in rat. Four groups have been considered including the vehicl...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13494
更新日期:2020-04-01 00:00:00
abstract::The lipid composition of the sperm membrane has been shown to exert a significant effect upon the functional quality of spermatozoa. We have studied fatty acid composition of the phospholipids in spermatozoa in asthenozoospermic and normozoospermic men and determined the ratio of polyunsaturated fatty acids (PUFAs) to...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2006.00735.x
更新日期:2006-10-01 00:00:00
abstract::We evaluated the reproductive potential of frozen/thawed testicular spermatozoa of azoospermic men with left varicocele. The role of testicular tissue telomerase assay (TTA) in the prediction of the presence of testicular spermatozoa pre- and post-varicocelectomy was investigated, as well. Therapeutic testicular biops...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2004.00615.x
更新日期:2004-06-01 00:00:00
abstract::Twisting of the spermatic cord is considered a popular problem in the urological field, which may lead to testicular necrosis and male infertility. Sitagliptin, a glucose-lowering agent, proved to have a vindicatory function in myocardial and renal ischaemia/reperfusion (I/R), but its role in testicular I/R has not ye...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13472
更新日期:2020-03-01 00:00:00
abstract::Testicular torsion/detorsion induces oxidative/nitrosative stress, inflammation and apoptosis of testicular tissues. Baicalin exerts antioxidant and anti-inflammatory properties. This study investigated the possible protective effect of baicalin against testicular torsion-detorsion injury in rats. Surgical testicular ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12580
更新日期:2017-02-01 00:00:00
abstract::Infertility affects up to 15% of reproductive-aged couples worldwide, with male factor being detected in 40%-50% of the cases. Proper sperm production is associated with the establishment of appropriate epigenetic marks in developing germ cells. Several studies have demonstrated the association between abnormal sperma...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12766
更新日期:2017-12-01 00:00:00
abstract::This trial aimed to assess the efficacy of on-demand oral dapoxetine versus topical lidocaine treatments for lifelong PE. Cases with lifelong PE were randomised to start treatment by oral dapoxetine 60 mg or topical lidocaine 10% spray. The intravaginal ejaculatory latency time (ILET), validated Arabic Index for PE (A...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13558
更新日期:2020-06-01 00:00:00
abstract::The aim of the study was to examine possible impacts of paroxetine and agomelatine on the levels of some components that constitute the seminal vesicle fluid. As a second purpose, it was also aimed to examine how possible negative effects induced by paroxetine on seminal vesicle fluid components were affected by kissp...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13538
更新日期:2020-05-01 00:00:00
abstract::We fractionated the whole human seminal plasma on DEAE Sephadex A-50 ion exchange columns. Complete separation was achieved in seven peaks using different salt concentrations in phosphate buffer pH 6. The seminal plasma proteins were separated by sodium dodecyl-sulphate polyacrylamide gel electrophoresis. Human semina...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1992.tb02616.x
更新日期:1992-03-01 00:00:00
abstract::Recent studies have revealed a high prevalence of leukocytospermia (> 1 x 10(6) white blood cells ml-1 semen) in male infertility patients in the USA and certain European countries, and have implicated white blood cells as a cause of infertility. Since leukocytospermia may often be attributed to male genital-tract inf...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1994.tb00783.x
更新日期:1994-05-01 00:00:00
abstract::Varicocele is one of causes of the declined sperm quality and low sperm production, which can lead to infertility in males. There are several experimental and epidemiological findings which support the idea that inflammatory mechanisms play an essential role in varicocele pathogenesis. Besides, in this pathological st...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12685
更新日期:2017-08-01 00:00:00
abstract::Little is known about the biological and clinical significance of bilaterally enlarged testes (bilateral megalotestes or macroorchidism). We have investigated clinical, endocrine and spermatological characteristics of 135 andrological patients with a testicular volume of more than 25 ml bilaterally. 135 patients with ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1995.tb01094.x
更新日期:1995-07-01 00:00:00
abstract::The aim of this study was to evaluate the production of artefacts during preparation and observation of human sperm for ultrastructural morphology and analyse the possible reasons of causing these artefacts. Under the scanning electron microscopy, damaged sperm heads (crack or/and rupture), necks (head-neck or head-mi...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13043
更新日期:2018-09-01 00:00:00
abstract::Erectile dysfunction could be an early sign of endothelial dysfunction and, therefore, of cardiovascular disease, with which it shares many risk factors. Among reversible risk factors, physical inactivity is one of the most important. Regular physical exercise has been shown to improve erectile function through differ...
journal_title:Andrologia
pub_type: 杂志文章,评审
doi:10.1111/and.13264
更新日期:2019-06-01 00:00:00
abstract::Iatrogenic obstruction of the vas deferens within the inguinal canal can be managed by direct on-site vasovasostomy. However, in cases with large defect of the vas, the anastomosis may be under tension. Dissecting through the site of a previous hernia repair is tedious, and may lead to recurrence of the hernia. The pr...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.2004.00624.x
更新日期:2004-10-01 00:00:00
abstract::The scope of this study was to evaluate the accuracy, precision and specificity of the sperm concentration measurements by the Strömberg-Mika Cell Motion Analyser (SM-CMA). Our data show that the instrument generally underscores the sperm concentration and therefore the uncorrected measurements must be corrected by th...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1995.tb02096.x
更新日期:1995-01-01 00:00:00
abstract::The aim of the study was to investigate whether or not the effect of icariin on erectile function of SHR is associated with inhibition of eNOS uncoupling. Ten 12-week-old male WKY rats and 10 age-matched male SHR were evenly randomised into SHR control group, SHR+ icariin treatment group, WKY control group and WKY+ ic...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.13084
更新日期:2018-11-01 00:00:00
abstract::To explore the aetiology of obstructive azoospermia (OA) in Chinese infertility patients, 133 OA patients was included in this study diagnosed and evaluated by one major specialist trained urological infertility. We retrospected the medical records to collect relative information. All of the patients had been underwen...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12509
更新日期:2016-09-01 00:00:00
abstract::In 3 mature bulls 2 injections (i.m.) of 150 mg 2-Br-alpha-ergocryptine (CB-154, Sandoz) within 48 hrs. decreased the plasma prolactin concentrations significantly for about 14 days (first experiment). In a second experiment, where treatment was repeated after 2 weeks, the period of maximal prolaction deficiency could...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1979.tb02149.x
更新日期:1979-01-01 00:00:00
abstract::An estrogen binding protein has been demonstrated in the cytosol of the epididymis and caudal lobe of prostate of immature rhesus monkey. Scatchard plot analyses were linear, suggesting a single class of high affinity binding sites for the synthetic estrogen, R-2858 (Moxestrol) with a Kd of 5.88 X 10(-10) mol/l and a ...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/j.1439-0272.1985.tb01016.x
更新日期:1985-07-01 00:00:00
abstract::The influence of the Wenchuan earthquake on semen quality of adult male survivors is unclear. We investigated the semen quality included 673 male survivors from the worse-affected counties in the earthquake between Aug 2008 and July 2013. Semen parameters including pH, volume, concentration, motility and morphology we...
journal_title:Andrologia
pub_type: 杂志文章
doi:10.1111/and.12573
更新日期:2016-12-01 00:00:00
abstract::Although testosterone replacement therapy can restore serum testosterone concentrations to normal level in late-onset hypogonadism patients, whether it can improve patients' quality of life remains uncertain. Therefore, we perform a meta-analysis of randomized controlled trials on this issue. Five randomized controlle...
journal_title:Andrologia
pub_type: 杂志文章,meta分析
doi:10.1111/and.12630
更新日期:2017-05-01 00:00:00