Hb Saint Nazaire (beta 103[G5]Phe-->Ile): a new example of polycythemia due to a hemoglobin variant with increased oxygen affinity.

abstract：:Tissue factor pathway inhibitor (TFPI) is a Kunitz-type proteinase inhibitor that has a crucial role in haemostasis and is primarily synthesized in the vascular endothelium. We investigated plasma total TFPI, antiphospholipid antibodies, and some other coagulation and fibrinolytic system parameters in 30 patients with...

journal_title：American journal of hematology

authors： Akarsu M,Demirkan F,Ozsan GH,Onen F,Yüksel F,Ozkan S,Undar B

更新日期：2001-12-01 00:00:00

abstract：:The lupus anticoagulant may be accompanied by an acquired factor II deficiency and bleeding. We report on a patient with a lupus anticoagulant and factor II (Fll) deficiency responsive to Danazol. Acquired hypoprothrombinemia (FII) with the lupus anticoagulant (LA) may be accompanied by a hemorrhagic diathesis. A 64-y...

journal_title：American journal of hematology

authors： Williams S,Linardic C,Wilson O,Comp P,Gralnick HR

更新日期：1996-12-01 00:00:00

abstract：:A 13-year-old boy presented with progressive bilateral lower limb weakness due to exradural granulocytic sarcoma of the spine. After surgical decompression and radiotherapy, he remained in complete remission 6 years after initial diagnosis. The possible reasons for the favorable outcome of this unique case are discuss...

journal_title：American journal of hematology

authors： Chan JK,Lau WH,Saw D

更新日期：1986-08-01 00:00:00

abstract：:The relationship between thrombocytopenia and the level of anticardiolipin antibodies (aCL) and/or the existence of lupus anticoagulant (LA) ware studied in 146 patients with systemic lupus erythematosus (SLE). These patients were divided into six groups: A, those LA positive with a high level of aCL (>10 U/ml) (10 ca...

journal_title：American journal of hematology

authors： Nojima J,Suehisa E,Kuratsune H,Machii T,Toku M,Tada H,Yamaguti K,Koike T,Kanakura Y,Kitani T,Amino N

更新日期：1998-05-01 00:00:00

abstract：:Autoimmune hemolytic anemia is thought to be mediated via auto-antibodies produced by lymphoid B cells. This may be an idiopathic process or secondary to an underlying infection or lymphoproliferative disorder. Conventional treatment comprises immunosuppression with corticosteroids and, in some cases, splenectomy. A p...

journal_title：American journal of hematology

authors： Ramanathan S,Koutts J,Hertzberg MS

更新日期：2005-02-01 00:00:00

abstract：:The purpose of this study was to determine if therapeutic levels of Rituximab could be achieved in a patient with renal failure being dialyzed and if Rituximab is removed by hemodialysis. A 54-year-old man with low-grade lymphoma and renal failure on hemodialysis received 8 weekly treatments of Rituximab at 375 mg/M(2...

journal_title：American journal of hematology

authors： Jillella AP,Dainer PM,Kallab AM,Ustun C

更新日期：2002-11-01 00:00:00

abstract：:Polycythemia vera (PCV) and multiple myeloma are both clonal disorders of hematopoietic stem cells. The simultaneous occurrence of these diseases in an individual patient is rare. A case of synchronous PCV and smoldering myeloma is presented and the literature is reviewed. The issues of clinical importance in this unu...

journal_title：American journal of hematology

authors： Fink L,Bauer F,Perry JJ

更新日期：1993-11-01 00:00:00

abstract：:Venous thromboembolism (VTE) recurs frequently. Greater height is associated with increased risk of incident VTE, but it is unclear whether height is related to risk of VTE recurrence. Recurrent VTE is associated with substantial morbidity and mortality, thus identifying individuals at greatest risk of experiencing a ...

journal_title：American journal of hematology

authors： Lutsey PL,Folsom AR

更新日期：2012-07-01 00:00:00

abstract：:Cephalosporins are commonly used drugs that interact with red blood cell membranes. They frequently cause a positive direct antiglobulin test but rarely cause hemolysis. A case of cefotetan-induced hemolytic anemia is described in which two types of antibodies were detected. One reacted with red blood cells by a hapte...

journal_title：American journal of hematology

authors： Ehmann WC

更新日期：1992-06-01 00:00:00

abstract：:Various in vitro studies and clinical observations suggest that Fanconi's anemia (FA) patients are unable to detoxify adequately superoxide anions (O2-) released by activated phagocytes. Recent studies have shown that certain lymphokines such as tumor necrosis factor-alpha (TNF-alpha) and interferon-gamma (IFN-gamma) ...

journal_title：American journal of hematology

authors： Schultz JC,Shahidi NT

更新日期：1993-02-01 00:00:00

abstract：:The authors report a 10-year-old boy with hepatosplenic gammadelta T-cell lymphoma, a rare form of lymphoma that is highly aggressive, exceedingly rare in children, and primarily seen in young men. Conventional multi-agent chemotherapy appears to be inadequate for cure. This is the first report with this type of lymph...

journal_title：American journal of hematology

authors： Gassas A,Kirby M,Weitzman S,Ngan B,Abla O,Doyle JJ

更新日期：2004-02-01 00:00:00

abstract：:Arsenic trioxide (As(2)O(3)) has been found effective in the treatment in the treatment of acute promyelocytic leukemia (APML). Most studies with As(2)O(3) involve patients with APML who have relapsed following standard therapy. Between January 1998 and July 2000, 14 patients were recruited for an ongoing trial of As(...

journal_title：American journal of hematology

authors： Mathews V,Balasubramanian P,Shaji RV,George B,Chandy M,Srivastava A

更新日期：2002-08-01 00:00:00

abstract：:An adolescent male patient developed functional asplenia in the course of graft versus host disease (GVHD) after successful allogeneic bone marrow transplantation (BMT) for aplastic anemia. Coincident with the onset of the asplenia, amelioration of the ongoing GVHD was observed. Unexpectedly, after 34 months of functi...

journal_title：American journal of hematology

authors： Demetrakopoulos GE,Tsokos GC,Levine AS

更新日期：1982-02-01 00:00:00

abstract：:Several histone deacetylase inhibitors (HDACi), including vorinostat, have been approved for the therapy of cutaneous T-cell lymphoma (CTCL). Emerging data suggest that HDACi may exert immune suppressive effects which would be disadvantageous for therapy of CTCL. We describe a patient with Sezary syndrome who was moni...

journal_title：American journal of hematology

authors： Stephen S,Morrissey KA,Benoit BM,Kim EJ,Vittorio CC,Nasta SD,Showe LC,Wysocka M,Rook AH

更新日期：2012-02-01 00:00:00

abstract：:The effect of short-chain aliphatic acids on [3H]deoxythymidine incorporation into DNA was studied in human mitogen-stimulated lymphocytes. Butyric acid at 1-2 mM level was strongly inhibitory; however, its hydroxy or amino derivatives were ineffective. Valeric and propionic acids were less inhibitory. Formic, acetic,...

journal_title：American journal of hematology

authors： Stolc V

更新日期：1982-09-01 00:00:00

abstract：:The expression of CD45 RA/RO antigen was investigated in neoplasms including cases expressing CD7 antigen as the sole pan-T antigen (n = 8), T-lineage acute lymphoblastic leukemia (ALL)/lymphoblastic lymphoma (LBL) at various stages of differentiation (n = 32), peripheral stage T-lineage leukemia (n = 10) and adult T-...

journal_title：American journal of hematology

authors： Kawano S,Tatsumi E,Yoneda N,Tani A,Nakamura F

更新日期：1995-05-01 00:00:00

abstract：:A case of idiopathic myelofibrosis (IMF) presenting with hypercalcemia and hypercalcitriolemia is reported. It is proposed that ectopic production of the active vitamin D metabolite related to ongoing clonal expansion in the bone marrow accounts for the hypercalcemic state. Consistently low levels of circulating type ...

journal_title：American journal of hematology

authors： Voss A,Schmidt K,Hasselbalch H,Junker P

更新日期：1992-03-01 00:00:00

abstract：:Peripheral serotonin (5-HT) has been involved in adverse cardiac remodeling and valve fibrosis. The peripheral levels of 5-HT mainly depend on its release from activated platelets and degradation by monoamine oxidase A (MAO-A). The SERAOPI study investigated the relationship between arterial serotoninergic system, deg...

journal_title：American journal of hematology

authors： Rouzaud-Laborde C,Delmas C,Pizzinat N,Tortosa F,Garcia C,Mialet-Perez J,Payrastre B,Sié P,Spreux-Varoquaux O,Sallerin B,Carrié D,Galinier M,Parini A,Lairez O

更新日期：2015-01-01 00:00:00

abstract：:Serologic diagnosis for Epstein-Barr virus (EBV) infection is problematic when patients receive exogenous immunoglobulin. We recently diagnosed primary EBV infection by detecting EBV-determined nuclear antigen (EBNA) and EBV-DNA in peripheral blood mononuclear cells (PBMC) using immunofluorescence, in situ hybridizati...

journal_title：American journal of hematology

authors： Okano M,Bashir RM,Davis JR,Purtilo DT

更新日期：1991-04-01 00:00:00

abstract：:We recently defined event-free survival at 24 months (EFS24) as a clinically relevant outcome for patients with DLBCL. Patients who fail EFS24 have very poor overall survival, while those who achieve EFS24 have a subsequent overall survival equivalent to that of the age- and sex-matched general population. Here, we de...

journal_title：American journal of hematology

authors： Maurer MJ,Jais JP,Ghesquières H,Witzig TE,Hong F,Haioun C,Thompson CA,Thieblemont C,Micallef IN,Porrata LF,Ribrag V,Nowakowski GS,Casasnovas O,Bologna S,Morschhauser F,Morrison VA,Peterson BA,Macon WR,Copie-Bergman C

更新日期：2016-02-01 00:00:00

abstract：:Two patients underwent allogeneic hematopoietic stem cell transplantation (HSCT) for acute myeloid leukemia. Chronic graft-versus-host disease (GVHD) developed, with persistent symptomatic oral lesions. At 2 and 6 years post-HSCT, both patients developed squamous cell carcinoma (SCC) of the tongue in areas previously ...

journal_title：American journal of hematology

authors： Szeto CH,Shek TW,Lie AK,Au WY,Yuen AP,Kwong YL

更新日期：2004-10-01 00:00:00

abstract：:A common side effect of opioids is nausea and vomiting; however, the incidence in hospitalized patients receiving opioids for acute pain is unknown. We performed a retrospective study in adult patients with sickle cell disease admitted for an acute pain crisis during a six-month period to evaluate the incidence of nau...

journal_title：American journal of hematology

authors： Shord SS,Chew L,Villano J

更新日期：2008-03-01 00:00:00

abstract：:Retroviral-mediated gene transfer into hematopoietic stem cells provides the only means of stable transduction of these cells and their progeny for use with a variety of potentially therapeutic genes. Expression of the Moloney amphotropic retroviral receptor-pit-2 or GLVR-2-is critical to the recognition and entry of ...

journal_title：American journal of hematology

authors： Kaubisch A,Ward M,Schoetz S,Hesdorffer C,Bank A

更新日期：1999-08-01 00:00:00

abstract：:A modified protein-bound cobalamin absorption test was used to study dietary cobalamin absorption in healthy adults of different age groups and patients with isolated low serum concentrations of cobalamin. Dietary cobalamin absorption was significantly reduced in healthy adults aged 55-75 years compared with young adu...

journal_title：American journal of hematology

authors： Scarlett JD,Read H,O'Dea K

更新日期：1992-02-01 00:00:00

abstract：:Cutaneous lymphoma is a disease characterized with massive skin infiltration of lymphoid malignant cells. They commonly express some T-cell markers, such as CD2, CD3, CD4, and CD7, and thus termed as CTCL (cutaneous T cell lymphoma). Here, we present a case with CD56/N-CAM-positive cutaneous lymphoma, which appears ly...

journal_title：American journal of hematology

authors： Adachi M,Maeda K,Takekawa M,Hinoda Y,Imai K,Sugiyama S,Yachi A

更新日期：1994-12-01 00:00:00

abstract：:We have investigated the methods for the maintenance of a pregnancy in a patient with thrombotic thrombocytopenic purpura (TTP), said condition, since 1984, having been controlled by a plasma infusion every 3 to 4 weeks. In a preliminary trial it was confirmed that an infusion of the high molecular weight fraction (HM...

journal_title：American journal of hematology

authors： Koyama T,Suehiro A,Kakishita E,Taira S,Isojima S,Norioka M,Ito K

更新日期：1990-11-01 00:00:00

abstract：:An 18-year-old girl with a preoperative platelet count of 216,000/cmm received 3 units of stored plasma at the time of surgery. Within 6 hours her platelet count had fallen to 5,000/mm3 and hemorrhagic manifestations appeared. One of the plasma donors was found to be P1A1 negative with an anti P1A1 antibody. The recip...

journal_title：American journal of hematology

authors： Nijjar TS,Bonacosa IA,Israels LG

更新日期：1987-06-01 00:00:00

abstract：:We have developed a rapid approach to detect the two most common alpha-thalassemia-2 (alpha-thal-2) determinants by the polymerase chain reaction (PCR) technique, which takes a few hours to complete. Specific oligonucleotides selectively amplify appropriate segments of the chromosome with the deletion and the normal c...

journal_title：American journal of hematology

authors： Baysal E,Huisman TH

更新日期：1994-07-01 00:00:00

abstract：:In this study, we investigated the incidence and prognostic impact of monosomal karyotype (MK) in 405 higher-risk Myelodysplastic Syndromes (MDS) patients treated with 5-AZA. The MK was present in 66 out of 405 (16.3%) patients, most of whom had complex karyotype (CK). MK was strongly associated with CK and the cytoge...

journal_title：American journal of hematology

authors： Papageorgiou SG,Vasilatou D,Kontos CK,Kotsianidis I,Symeonidis A,Galanopoulos AG,Hatzimichael E,Megalakaki A,Poulakidas E,Diamantopoulos P,Vassilakopoulos TP,Zikos P,Papadaki H,Mparmparousi D,Bouronikou E,Panayiotidis P,V

更新日期：2018-07-01 00:00:00

abstract：:In this study, we examined differences in inpatient costs, length of stay, and in-hospital mortality between hospitalizations for patients with and without sickle cell disease (SCD) undergoing high-volume surgical procedures. We used Clinical Classification Software (CCS) codes to identify discharges in the 2002-2005 ...

journal_title：American journal of hematology

authors： Dinan MA,Chou CH,Hammill BG,Graham FL,Schulman KA,Telen MJ,Reed SD

更新日期：2009-11-01 00:00:00