Reactivation and dissemination of blastomycosis complicating Hodgkin's disease: a case report and review of the literature.

Abstract:

:Patients presenting with Hodgkin's disease (HD) may show lung involvement characterized by contiguous spread from ipsilateral hilar lymph nodes. Lung consolidation or noncontiguous pulmonary involvement makes an alternative diagnosis more likely. This report describes a patient with HD in whom concurrent pulmonary blastomycosis was recognized only after chemotherapy had started and dissemination had occurred. Although Blastomyces dermatitidis may behave as an opportunist pathogen, there are no previous reports of blastomycosis in patients with HD. Undiagnosed active opportunistic infection at the time of diagnosis of HD may complicate staging as well as treatment. Biopsy of lung lesions with stain and culture for opportunistic pathogens should be considered in patients with newly diagnosed HD disease and atypical patterns of lung involvement.

journal_name

Am J Hematol

authors

Winquist EW,Walmsley SL,Berinstein NL

doi

10.1002/ajh.2830430211

subject

Has Abstract

pub_date

1993-06-01 00:00:00

pages

129-32

issue

2

eissn

0361-8609

issn

1096-8652

journal_volume

43

pub_type

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