Human thymus antigen: characterization and its expression on human leukemias.

abstract：:Sitosterolemia (phytosterolemia) is a rare inherited sterol storage disorder, characterized by significantly elevated plasma levels of plant sterols. The clinical features of sitosterolemia are xanthomas, premature atherosclerosis, arthritis, and, occasionally, liver function impair and hematologic abnormalities. This...

journal_title：American journal of hematology

authors： Wang Z,Cao L,Su Y,Wang G,Wang R,Yu Z,Bai X,Ruan C

更新日期：2014-03-01 00:00:00

abstract：DISEASE OVERVIEW:Waldenström macroglobulinemia (WM) is a lymphoplasmacytic lymphoma with immunoglobulin M (IgM) monoclonal protein. Clinical features include anemia, thrombocytopenia, hepatosplenomegaly, and lymphadenopathy. DIAGNOSIS:Presence of IgM monoclonal protein associated with 10% clonal lymphoplasmacytic cell...

journal_title：American journal of hematology

authors： Gertz MA

更新日期：2011-05-01 00:00:00

abstract：:Hemophagocytic syndrome (HPS) is an unusual acute syndrome presenting with fever, hepatosplenomegaly, and cytopenias. The hallmark of HPS is the accumulation of activated macrophages that engulf hematopoietic cells in the reticuloendothelial system. Most cases of HPS in adults are secondary to infection or malignancy,...

journal_title：American journal of hematology

authors： Goldschmidt N,Gural A,Kornberg A,Spectre G,Shopen A,Paltiel O

更新日期：2004-08-01 00:00:00

abstract：:The effect of the synthetic vasopressin derivative 1-desamino-8D-arginine vasopressin (DDAVP = desmopressin) on bleeding time was studied in three patients with Hermansky Pudlak syndrome. A good response was observed in this type of storage pool disease. DDAVP might be useful in managing the bleeding disorder found in...

journal_title：American journal of hematology

authors： Wijermans PW,van Dorp DB

更新日期：1989-03-01 00:00:00

abstract：:Cerebrospinal fluid beta-2-microglobulin (CSF-beta 2m) was measured longitudinally in 48 patients affected by acute lymphoblastic leukemia (ALL). Thirteen developed a central nervous system (CNS) involvement during the course of the disease; although moderately higher mean CSF-beta 2m levels were found in these subjec...

journal_title：American journal of hematology

authors： Musto P,Tomasi P,Cascavilla N,Ladogana S,La Sala A,Melillo L,Nobile M,Castoldi G,Carotenuto M

更新日期：1988-08-01 00:00:00

abstract：:Granulocyte-macrophage colony-stimulating factor (GM-CSF) (250 microg/m2) was administered subcutaneously to 7 normal volunteers for up to 14 days to study its effects on neutrophil kinetics and function. With treatment, blood neutrophil counts rose gradually to peak at 3 1/2 times baseline by day 14. At day 5 marrow ...

journal_title：American journal of hematology

authors： Dale DC,Liles WC,Llewellyn C,Price TH

更新日期：1998-01-01 00:00:00

abstract：:Iron studies were compared in 434 patients from 80 hemochromatosis families classified as putative homozygotes, heterozygotes, and normal by HLA typing. There were 28 of 255 (11%) heterozygotes with an elevated serum ferritin and 22 of 255 (8.6%) with an elevated transferrin saturation. Serum ferritin (140 +/- 10.2 mi...

journal_title：American journal of hematology

authors： Adams PC

更新日期：1994-02-01 00:00:00

abstract：:Autologous 51Cr-platelet kinetic studies were performed in splenectomized mongrel dogs. Mean survival time of PRP-platelets was 5.4 +/- 1.5 (SD) days (n = 6). The curves, though slightly curvilinear, showed mostly a linear type of decay, denoting that platelet removal from the circulation is mainly determined by aging...

journal_title：American journal of hematology

authors： Mezzano D,Aranda E,Foradori A,Rodríguez S,Lira P

更新日期：1984-01-01 00:00:00

abstract：:A 69-year-old man with immunoblastic lymphadenopathy and autoimmune hemolytic anemia who had no previous exposure to blood products developed a severe febrile nonhemolytic transfusion reaction following the initial infusion of packed red blood cells. The reaction recurred with transfusion of packed red blood cells, bu...

journal_title：American journal of hematology

authors： Barnes HM,Poon MC,Huang ST,Conrad ME,Lin J,McGowan EI

更新日期：1983-02-01 00:00:00

abstract：:Autoimmune hemolytic anemia (AIHA) associated with giant cell hepatitis (GCH) is a rare disorder in infants. AIHA usually precedes the development of liver disease by months to years. Early recognition of the disease and prompt institution of immunosuppressive therapy results in clinical remission and prevents liver d...

journal_title：American journal of hematology

authors： Kashyap R,Sarangi JN,Choudhry VP

更新日期：2006-03-01 00:00:00

abstract：:Thrombotic thrombocytopenic purpura (TTP) is a microangiopathy syndrome caused by a congenital or acquired deficiency of ADAMTS13, a plasma metalloprotease that cleaves von Willebrand factor (VWF) and thus prevents the formation of platelet-rich thrombi in the microcirculation. TTP can be fatal if not appropriately an...

journal_title：American journal of hematology

authors： Peyvandi F,Mannucci PM,Valsecchi C,Pontiggia S,Farina C,Retzios AD

更新日期：2013-10-01 00:00:00

abstract：:The acquired JAK2 V617F mutation is common in patients with myeloproliferative neoplasms. We previously showed that JAK2 V617F is also found in coronary patients, most of them affected by coronary atherosclerosis. Peripheral arterial disease (PAD) is another important manifestation of atherosclerosis. However, prevale...

journal_title：American journal of hematology

authors： Muendlein A,Kinz E,Gasser K,Leiherer A,Rein P,Saely CH,Grallert H,Peters A,Fraunberger P,Drexel H,Lang AH

更新日期：2015-01-01 00:00:00

abstract：:Autologous stem cell transplantation (ASCT) is feasible and effective in selected older patients with Multiple Myeloma, but specific criteria for evaluating ASCT eligibility in elderly patients are lacking. We evaluated 131 patients aged 65-75 considered for ASCT at our center: The Charlson Comorbidity Index (CCI), He...

journal_title：American journal of hematology

authors： Belotti A,Ribolla R,Cancelli V,Crippa C,Bianchetti N,Ferrari S,Bottelli C,Cattaneo C,Tucci A,De La Fuente Barrigon C,Rossi G

更新日期：2020-07-01 00:00:00

abstract：:The expression of a human erythroid cell surface antigen recognized by monoclonal antibody (mAB) HAE9 has been studied on peripheral blood reticulocytes by one- and two-color flow cytometry. Total reticulocyte count was determined using Thiazole Orange (TO) and flow cytometry. In normal individuals, 4.56% of reticuloc...

journal_title：American journal of hematology

authors： Mechetner EB,Sedmak DD,Barth RF

更新日期：1991-09-01 00:00:00

abstract：:The clinical features of patients with splenic marginal zone cell lymphoma (SMZCL) have rarely been reported. In the present study, immunological abnormalities, particularly hematological abnormalities, observed in SMZCL were described. Autoimmune hemolytic anemia, immune thrombocytopenia, and appearance of lupus anti...

journal_title：American journal of hematology

authors： Murakami H,Irisawa H,Saitoh T,Matsushima T,Tamura J,Sawamura M,Karasawa M,Hosomura Y,Kojima M

更新日期：1997-11-01 00:00:00

abstract：:An 18-year-old girl with a preoperative platelet count of 216,000/cmm received 3 units of stored plasma at the time of surgery. Within 6 hours her platelet count had fallen to 5,000/mm3 and hemorrhagic manifestations appeared. One of the plasma donors was found to be P1A1 negative with an anti P1A1 antibody. The recip...

journal_title：American journal of hematology

authors： Nijjar TS,Bonacosa IA,Israels LG

更新日期：1987-06-01 00:00:00

abstract：DISEASE OVERVIEW:Ring sideroblasts (RS) are erythroid precursors with abnormal perinuclear mitochondrial iron accumulation. Two myeloid neoplasms defined by the presence of RS, include refractory anemia with ring sideroblasts (RARS), now classified under myelodysplastic syndromes with RS (MDS-RS) and RARS with thromboc...

journal_title：American journal of hematology

authors： Patnaik MM,Tefferi A

更新日期：2017-03-01 00:00:00

abstract：:Cephalosporins are commonly used drugs that interact with red blood cell membranes. They frequently cause a positive direct antiglobulin test but rarely cause hemolysis. A case of cefotetan-induced hemolytic anemia is described in which two types of antibodies were detected. One reacted with red blood cells by a hapte...

journal_title：American journal of hematology

authors： Ehmann WC

更新日期：1992-06-01 00:00:00

abstract：:Fetal calf serum (FCS) is used as a component of the media for cells grown in culture. However, the high cost of FCS has stimulated a search for a possible alternative. Approximately 10% of human platelet concentrates prepared for clinical transfusions are outdated. Sera prepared from platelet concentrates were compar...

journal_title：American journal of hematology

authors： Schwartz KA,Lu G,Trosko JE,Chang CC

更新日期：1984-07-01 00:00:00

abstract：:Ten previously untreated elderly patients with hypocellular acute leukemia received a low dose of cytosine arabinoside (Ara-C), 10 mg/m2 injected subcutaneously every 12 hours for 14-28 days. Six patients achieved a complete remission (CR) for periods ranging for 6-23 months (median 8.5 months) and the others had a pa...

journal_title：American journal of hematology

authors： Kanamori H,Maruta A,Miyashita H,Harano H,Fukawa H,Matsuzaki M,Motomura S,Mohri H,Kodama F,Okubo T

更新日期：1992-01-01 00:00:00

abstract：:The relationship between thrombocytopenia and the level of anticardiolipin antibodies (aCL) and/or the existence of lupus anticoagulant (LA) ware studied in 146 patients with systemic lupus erythematosus (SLE). These patients were divided into six groups: A, those LA positive with a high level of aCL (>10 U/ml) (10 ca...

journal_title：American journal of hematology

authors： Nojima J,Suehisa E,Kuratsune H,Machii T,Toku M,Tada H,Yamaguti K,Koike T,Kanakura Y,Kitani T,Amino N

更新日期：1998-05-01 00:00:00

abstract：:A 50-year-old woman with muscular fatigue and monoclonal gammopathy of unknown significance was shown to have high levels of antibodies against the acetylcholine receptor of the skeletal muscle endplate. The specific antibody activity was exclusively associated with the monoclonal component. There were no objective si...

journal_title：American journal of hematology

authors： Ahlberg RE,Lefvert AK

更新日期：1988-09-01 00:00:00

abstract：:Secondary acute myeloid leukemia (sAML) traditionally has inferior outcomes compared to de novo AML. Allogeneic hematopoietic cell transplantation (HCT) is the sole potentially curative therapy. This study analyzes the outcomes for unmanipulated haploidentical HCT (haploHCT) for sAML using the Acute Leukemia Working P...

journal_title：American journal of hematology

authors： Li Z,Labopin M,Ciceri F,Blaise D,Tischer J,Ehninger G,Van Lint MT,Koc Y,Santarone S,Forcade E,Castagna L,Polge E,Mailhol A,Ruggeri A,Mohty M,Savani BN,Nagler A

更新日期：2018-06-01 00:00:00

abstract：:Hypereosinophilic syndrome (HES) is a rare disorder that can manifest in various organ systems. We report the case of a 54-year-old woman with a remote history of seizure disorder who presented with early signs of right-sided heart failure. Laboratory studies showed significant eosinophilia (8 x 10(9) l(-1)). Computed...

journal_title：American journal of hematology

authors： Chao BH,Cline-Parhamovich K,Grizzard JD,Smith TJ

更新日期：2007-10-01 00:00:00

abstract：:Extensive extralymphatic Hodgkin disease developed in a young man with common variable immunodeficiency manifested by hypogammaglobulinemia, recurrent sinopulmonary infections, and multiple autoimmune phenomena. Both humoral and cell-mediated immune dysfunction were present prior to treatment. After two cycles of chem...

journal_title：American journal of hematology

authors： Fesus SM,Hagemeister FB,Manning J

更新日期：1989-10-01 00:00:00

abstract：:Intensive induction chemotherapy using anthracycline and cytarabine backbone is considered the most effective upfront therapy in physically fit older patients with acute myeloid leukemia (AML). However, outcomes of the standard induction in elderly AML are inferior to those observed in younger patients, and they are s...

journal_title：American journal of hematology

authors： Pluta A,Robak T,Wrzesien-Kus A,Katarzyna Budziszewska B,Sulek K,Wawrzyniak E,Czemerska M,Zwolinska M,Golos A,Holowiecka-Goral A,Kyrcz-Krzemien S,Piszcz J,Kloczko J,Mordak-Domagala M,Lange A,Razny M,Madry K,Wiktor-Jedrze

更新日期：2017-04-01 00:00:00

abstract：:Epstein-Barr virus (EBV) occasionally infects T and NK cells and causes EBV-infected T/NK-cell lymphoproliferative disease (LPD), which comprises chronic active EBV infection, EBV-associated hemophagocytic syndrome, mosquito allergy, hydroa vacciniforme, aggressive NK-cell leukemia, and NK/T-cell lymphoma. The diagnos...

journal_title：American journal of hematology

authors： Sawada A,Sato E,Koyama M,Higuchi B,Kusuki S,Kim JY,Takeshita Y,Sakata A,Sakata N,Okamura T,Yasui M,Inoue M,Kawa K

更新日期：2006-08-01 00:00:00

abstract：:Serologic diagnosis for Epstein-Barr virus (EBV) infection is problematic when patients receive exogenous immunoglobulin. We recently diagnosed primary EBV infection by detecting EBV-determined nuclear antigen (EBNA) and EBV-DNA in peripheral blood mononuclear cells (PBMC) using immunofluorescence, in situ hybridizati...

journal_title：American journal of hematology

authors： Okano M,Bashir RM,Davis JR,Purtilo DT

更新日期：1991-04-01 00:00:00

abstract：:Some evidence has shown that platelet crossmatching is useful in multitransfused patients with hypoplastic bone marrows who are refractory to platelet therapy through alloimmunization. Several immunoglobulin binding assays other than enzyme-linked immunospecific assay (ELISA) have been studied previously. We performed...

journal_title：American journal of hematology

authors： Brubaker DB,Duke JC,Romine M

更新日期：1987-04-01 00:00:00

abstract：:Intravenous morphine is the treatment of choice for severe pain during vaso- occlusive crisis in sickle cell disease (SCD). However, side effects of morphine may hamper effective treatment, and high plasma levels of morphine are associated with severe complications such as acute chest syndrome. Furthermore, adequate d...

journal_title：American journal of hematology

authors： van Beers EJ,van Tuijn CF,Nieuwkerk PT,Friederich PW,Vranken JH,Biemond BJ

更新日期：2007-11-01 00:00:00