Abstract：
:Blastocysts hominis, a protozoon considered to be a nonpathogen intestinal commensal, is now discussed to be a cause of intestinal infection under certain circumstances, e.g., immunosuppression. There are two published cases of Blastocysts infection complicated by arthritis which was classified as "reactive" in one case, "infectious" in the other. We report a third case: A 46-year-old female patient developed a chronic diarrhea and oligoarthritis some days after returning from a trip to Senegal. Arthritis was refractory against treatment with NSAID and corticosteroids. Finally, a 3-week course of treatment with metronidazole resulted in a complete remission of arthritis, gastrointestinal symptoms, and inflammation signs (ESR, CRP). The course in our case, as well as the detection of Blastocysts hominis in synovial fluid in another case, implicate an infectious rather than a reactive etiology of arthritis.
journal_name
Z Rheumatoljournal_title
Zeitschrift fur Rheumatologieauthors
Krüger K,Kamilli I,Schattenkirchner Msubject
Has Abstractpub_date
1994-03-01 00:00:00pages
83-5issue
2eissn
0340-1855issn
1435-1250journal_volume
53pub_type
杂志文章abstract：:Self-administered patient-centered questionnaires have been shown to be practical, reliable and valid in terms of evaluating functional limitations in rheumatic diseases. In systemic sclerosis a modified version of the HAQ and condition-specific questionnaires have been used. The Health Assessment Questionnaire (HAQ) ...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-004-0674-4
更新日期：2004-12-01 00:00:00
abstract：:This article gives a comprehensive overview of diffuse interstitial lung diseases especially those associated with connective tissue diseases. Interstitial lung diseases (ILD) represent a heterogeneous group of diseases of very different and partially unknown etiologies. Therefore, an exact classification of the ILD i...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-003-0485-z
更新日期：2003-04-01 00:00:00
abstract：:Autoimmune hemolysis is a rare complication of systemic rheumatic diseases. We report on a 68-year-old female patient with established, long-standing rheumatoid arthritis, who complained of progressive weakness and worsening of her arthralgia under therapy with leflunomide. Physical and laboratory examination revealed...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-010-0607-3
更新日期：2010-08-01 00:00:00
abstract：:In recent years the great progress in knowledge on bone cell biology has allowed identification of molecular structures that can be targeted with pinpoint precision (druggable targets). Osteoclasts are regulated via the RANK-RANK-ligand (RANKL) signaling pathway and osteoblasts via the Wnt signaling pathway, both of w...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-016-0102-6
更新日期：2016-06-01 00:00:00
abstract：:Three new findings are reviewed that help to understand the mechanisms of action of anti-rheumatic gold drugs, such as disodium aurothiomalate (Na2Au(I)TM): i) We found that Na2Au(I)TM selectively inhibits T-cell receptor-mediated antigen recognition by murine CD4+ T-cell hybridomas specific for antigenic peptides con...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：
更新日期：1996-09-01 00:00:00
abstract：BACKGROUND:Sport is becoming increasingly more important in our society. Due to the changing age spectrum with a greater number of elderly and substantially more active people, an increasing number of people with underlying orthopedic diseases are becoming interested in participating in sport. MATERIAL AND METHODS:Thi...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-013-1341-4
更新日期：2014-06-01 00:00:00
abstract：:The treatment of rheumatic diseases with bioloics has significantly improved the prognosis of patients. Currently, there are 13 preparations available in Germany for the treatment of patients with inflammatory rheumatic diseases. These original preparations generally have-depending on the individual country-15 years o...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-017-0407-0
更新日期：2018-02-01 00:00:00
abstract：:In the last years some important therapies were introduced in the treatment of rheumatoid arthritis (RA), which represent a significant clinical advance. This concerns the introduction of TNF blockade with etanercept and inflixmab, the combination of DMARDs, leflunomide and the COX-2-specific inhibitors. In the year 2...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s003930170011
更新日期：2001-12-01 00:00:00
abstract：:Bone morphogenetic proteins (BMPs) belong to the transforming growth factor-beta superfamily. Their potential for organ and tissue regeneration and repair has been intensively investigated in recent years. Studies on fetal development have demonstrated the important role of these proteins for the development and diffe...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-005-0665-0
更新日期：2005-09-01 00:00:00
abstract：:The classical septic bacterial arthritis is a rare event, but can be distinguished by unequivocal signs such as fibrin exudation and neutrophilic masses (pus). For a long time we have been observing an abortive form of bacterial arthritis in biopsies which subsides spontaneously without antibiotic intervention. Only v...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-007-0251-8
更新日期：2008-02-01 00:00:00
abstract：:Rheumatoid arthritis (RA) and systemic lupus erythematosus (SLE) are associated with increased mortality, largely as a consequence of cardiovascular (CV) disease. Studies found relative risk ratios of 2 for myocardial infarction in RA and up to 7 for myocardial infarction in SLE patients.Beyond the traditional CV risk...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-009-0585-5
更新日期：2010-10-01 00:00:00
abstract：:Transmitting a substantial amount of basic knowledge in Rheumatology to all medical students is essential for the future medical care of patients with rheumatic diseases for two reasons: on the one hand, future general practitioners will need to master the patterns of rheumatic diseases to recognize them fast enough i...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-020-00933-w
更新日期：2020-12-02 00:00:00
abstract：BACKGROUND:Early detection of patients with axial spondylarthritis (axSpA) in primary care is difficult. The combination of various parameters indicative of inflammatory back pain (AWARE criteria) was found to be beneficial in an initial study. OBJECTIVE:Review of the criteria for the identification of young patients ...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-018-0550-2
更新日期：2019-08-01 00:00:00
abstract：:Recent Deutsche Gesellschaft für Rheumatologie (DGRh, German Society of Rheumatology) guidelines emphasized the significance of coordinated multidisciplinary care and rehabilitation of patients with inflammatory rheumatic diseases. Nationwide data from the German pension insurance funds showed that inpatient rehabilit...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-013-1259-x
更新日期：2014-03-01 00:00:00
abstract：:409 unselected outpatients were asked standardized expert system questions on the medical history of joint complaints. An average number of 30.4 +/- 6.6 out of 60 questions with 346 different answers were asked in a mean time of 20.1 +/- 6.6 min. This time, required for the questions to be displayed on the computer sc...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1991-07-01 00:00:00
abstract：:Interstitial nephritis is responsible for about 12 % of end-stage renal disease in Germany. It comprises an etiologically heterogenous group of inflammatory renal disorders which primarily affect the renal interstitium and tubuli. Drugs, predominantly antibiotics, nonsteroidal anti-inflammatory drugs and proton pump i...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-014-1482-0
更新日期：2015-05-01 00:00:00
abstract：INTRODUCTION:Only insufficient data are available regarding the question whether treatment with immunosuppressants or biologicals is feasible and safe in patients with a history of malignancy. METHOD:Literature search via PubMed, EULAR abstracts and ACR abstracts from 2013 to 2015. RESULTS:The Société Francaise de Rh...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00393-015-0034-6
更新日期：2016-02-01 00:00:00
abstract：:The aim of this review is to critically analyze the evidence of therapeutic ultrasound between 0.8 and 3 MHz for treating musculoskeletal diseases. Relevant randomized, controlled, clinical trials and systematic reviews published on this topic have been taken into consideration.There was evidence of effectiveness for ...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-009-0457-z
更新日期：2009-09-01 00:00:00
abstract：:A 41-year-old patient with mutilating rheumatoid arthritis and progressive systemic sclerosis, who developed a chronic myeloproliferative disorder polycythemia vera was observed. Some of the pathogenetic aspects of this case with special respect to the function abnormalities of peripheral blood polymorphonuclear cells...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1992-09-01 00:00:00
abstract：:Among the rheumatic diseases, systemic lupus erythematosus (SLE) reveals the highest frequency of central nervous symptoms. Psychiatric abnormalities are present in over 90% of the patients, if very mild cognitive impairment is included. The psychiatric syndromes listed by the American College of Rheumatologists encom...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-004-0618-z
更新日期：2004-04-01 00:00:00
abstract：:Twenty-three patients with rheumatoid arthritis and relevant anemia (hemoglobin < 11 g/dl) received recombinant erythropoietin (epo) in a therapy study; 90% were responders. A positive correlation of the total epo dose and the amelioration of parameters of red cell line and a negative correlation of the effect of epo ...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1995-01-01 00:00:00
abstract：:Fiftythree patients with progressive systemic sclerosis were studied. Four of them (3 males) had the diffuse form of the disease. The skin manifestation of this clinical picture is characterized by diffuse progression of the cutaneous sclerosis over almost the whole body surface, except for the hands where it eventual...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1976-07-01 00:00:00
abstract：:In recent years German authorities established a global budget for health care expenditures solely based on macroeconomic aspects. In the last year there have been attempts to define differentiated budgets for chronic diseases. These plans are mainly defined by quality aspects on the process level (creating networks) ...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s003930050134
更新日期：1998-12-01 00:00:00
abstract：:Personalized healthcare tries to predict the effectiveness and safety in individual therapeutic approaches by defining individual patient characteristics (biomarkers), while stratification uses diagnostic patterns for groups of patients for prediction of therapeutic response with less adverse reactions caused by the d...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-011-0886-3
更新日期：2013-02-01 00:00:00
abstract：:The knee joint is often involved in rheumatoid arthritis. Despite ever-improving medical antirheumatic therapies, surgical treatment continues to play an important role in optimal multidisciplinary care. The aim of the present work is to process current orthopedic surgical therapy procedures on the knee joint accordin...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-018-0534-2
更新日期：2018-12-01 00:00:00
abstract：:1436 young men were investigated clinically and radiologically for rheumatic sacro iliitis. In two men (1.4%) definite bilateral sacro iliitis was diagnosed. In 18 cases (12.5%) the signs were not sufficient to make a definite diagnosis. They were regarded as suspected iliitis. For comparison the cards of 6138 patient...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1977-09-01 00:00:00
abstract：:The international treat-to-target initiative including rheumatoid arthritis (RA) patients has defined remission or alternatively low disease activity as treatment goals. In Germany representatives of the medical profession, such as doctors, nurses and including the Deutsche Rheuma-Liga, are deliberating how to adapt a...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章,评审
doi：10.1007/s00393-011-0773-y
更新日期：2011-10-01 00:00:00
abstract：:The enzyme poly-(ADP-ribose) polymerase (PARP) is localized within the cell nucleus and catalyzes DNA-repair. During programmed cell death (apoptosis), PARP is enzymatically cleaved. Detection of the cleavage products is characteristic for apoptosis. In patients with systemic lupus erythematosus (SLE), the highly orde...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：10.1007/s00393-006-0045-4
更新日期：2006-10-01 00:00:00
abstract：:Peripheral blood lymphocytes of patients with rheumatoid arthritis, psoriatic arthritis and healthy controls, isolated by a ficoll density gradient, were incubated with different concentrations of histamine, cimetidine and diphenhydramine (DPH) and simultaneously stimulated with phytohemagglutinine (PHA). In compariso...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1984-07-01 00:00:00
abstract：:The diagnosis of chondrocalcinosis is based on typical radiographic findings and synoviaanalysis. We examined 10 patients with chondrocalcinosis to see whether pathognomonic findings of the disease could also be seen by ultrasound. Ultrasound and x-ray findings were compared. Calcifications of the knee menisci were se...
journal_title：Zeitschrift fur Rheumatologie
pub_type： 杂志文章
doi：
更新日期：1990-05-01 00:00:00
