Abstract：
:To clarify the clinical significance of the status of surgical margins, especially the dissected margin in the transverse direction, a clinicopathologic study was performed on 60 patients with carcinoma of the bile duct who underwent radical resection. The patients in group A (n = 28) had no cancer invasion within 5 mm of the dissected margin in the transverse direction. They had a higher incidence of the well differentiated type of carcinoma and a lower incidence of lymph node metastasis and microscopic tumor extension than the patients in group B. Group B (n = 32) included patients with cancer involvement within 5 mm of the dissected margin in the transverse direction. Some group A patients were found to have advanced carcinoma of the lower bile duct, but they were the only ones whose lesions were at an early stage (e.g., lesion restricted to subserosal involvement or less) among those with carcinoma of the hepatic duct and the upper and middle bile ducts. Local recurrence was found to occur more frequently as the tumor approached the liver, and the incidence of local recurrence was significantly higher in patients in group B than in group A (75.0% versus 28.5%). These results indicate that patients with cancer invasion within 5 mm of the surgical margin develop early recurrence of tumor even after conventional radical resection and that further radical dissection of the hepatoduodenal ligament with hepatectomy or pancreatoduodenectomy may be required to improve survival for these cases.
journal_name
World J Surgjournal_title
World journal of surgeryauthors
Ogura Y,Takahashi K,Tabata M,Mizumoto Rdoi
10.1007/BF00298931subject
Has Abstractpub_date
1994-09-01 00:00:00pages
778-84issue
5eissn
0364-2313issn
1432-2323journal_volume
18pub_type
杂志文章abstract：BACKGROUND:Chronic anal fissure (CAF) is a linear split of the anoderm. The minimally invasive management of CAF such as botulinum toxin (BT) injection is recommended. However, the exact efficient dose of BT, number of injections per session and the injection sites are still debatable. The aim of this analysis was to a...
journal_title：World journal of surgery
pub_type： 杂志文章,meta分析,评审
doi：10.1007/s00268-016-3693-9
更新日期：2016-12-01 00:00:00
abstract：BACKGROUND:The extrahepatic surgical technique in liver resection can be divided into glissonean pedicle transection and glissonean separated transection approaches. In this study, we compared remnant liver function and liver regeneration involving the Spiegel lobe between these two approaches regarding Spiegel lobe-pr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05548-5
更新日期：2020-09-01 00:00:00
abstract：:Persistent pain after hernia repair is common, although it is usually mild. In 3% of patients it is severe, however, and has significant effects on work and social activities. The purpose of this review was to examine factors that affect pain after hernia repair. Although the type of anaesthetic used, local or general...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-005-7903-0
更新日期：2005-08-01 00:00:00
abstract：:Since the pathogenesis of endocrine ophthalmopathy is unclear, there has been little agreement on the treatment of the disease. The influence of thyroid surgery on endocrine ophthalmopathy is controversial. To evaluate the effect of thyroid surgery on the course of the disease, we developed a special ophthalmopathy in...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF01658552
更新日期：1990-05-01 00:00:00
abstract：BACKGROUND:The prognosis of advanced hepatocellular carcinoma (HCC) remains poor, particularly in patients with tumor thrombi (TT) in the major vessels. PATIENTS AND METHODS:From July 1992 to October 2004, 161 patients diagnosed as having advanced HCC with major vascular involvement were seen consecutively at our hosp...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-005-0250-3
更新日期：2006-03-01 00:00:00
abstract：BACKGROUND:The objective of the present study was to identify logistic regression models with better survival prediction than the Trauma and Injury Severity Score (TRISS) method in assessing blunt trauma (BT) victims in Japan and Thailand. An additional aim was to demonstrate the feasibility of probability of survival ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-012-1498-z
更新日期：2012-04-01 00:00:00
abstract：BACKGROUND:Intraoperative identification of the difficult-to-spot parathyroid gland is critical during surgery for thyroid and parathyroid disease. Recently, intrinsic fluorescence of the parathyroid gland was identified, and a new method was developed for intraoperative detection of the parathyroid with an original fl...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-3903-0
更新日期：2017-06-01 00:00:00
abstract：:Histologically differentiated adenocarcinoma satisfies one of the criteria for limited surgery for mucosal carcinoma of the stomach: however, the histology of the endoscopic biopsy specimen is often different from that of the resected specimen. The medical records of 1018 early gastric carcinomas were retrospectively ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900483
更新日期：1998-08-01 00:00:00
abstract：BACKGROUND:The purpose of the present study was to analyze the risk multi-factors of postoperative cardiac arrhythmia for elderly patients with esophageal or cardiac carcinoma. METHODS:A total of 756 operations for elderly patients (>65 years of age) with esophageal or cardiac carcinoma were performed in our departmen...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0222-0
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:The morbidity and mortality of anastomotic complications after esophagectomy have gradually decreased in recent years. However, swallowing difficulties and reflux continue to burden patients jeopardizing their quality of life. In the present study we performed endoscopic evaluation of the outcomes of esophag...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9664-z
更新日期：2008-09-01 00:00:00
abstract：:Thoracic and thoracoabdominal penetrating wounds are frequently encountered in urban medical centers in the United States. This study was undertaken to determine the clinical characteristics and in hospital outcome of these injuries. This was a longitudinal, nonblinded study using the established standard of care of p...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/BF03215862
更新日期：2001-09-01 00:00:00
abstract：:The major goal of wound healing biology is to determine how a wound can be induced to repair damaged tissue faster and more efficiently. Enhancement of dermal and epidermal regeneration is an extremely important goal for the treatment of many different types of wounds. Exogenous application of growth factors to the wo...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s00268-004-2062-2
更新日期：2005-01-01 00:00:00
abstract：:The lack of sufficient suitable human donor lungs for the many patients requiring pulmonary transplantation as life-saving therapy for end-stage lung diseases has generated extensive interest in cross-species lung transplantation. Ethical concerns and those of animal rights advocates have prompted studies of nonprimat...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900332
更新日期：1997-11-01 00:00:00
abstract：:The introduction of laparoscopic techniques for the management of biliary stone disease has expanded the therapeutic choices for surgeons confronted with choledocholithiasis. As new strategies emerge, the treatment of cholelithiasis and choledocholithiasis remains controversial. This paper discusses the options availa...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/s002689900531
更新日期：1998-11-01 00:00:00
abstract：BACKGROUND:Obesity and rapid weight loss after bariatric surgery are risk factors for gallstone disease. OBJECTIVES:The present study sought to evaluate the feasibility of selective concomitant cholecystectomy only in patients with symptomatic disease and study risk factors for the development of symptomatic gallstone...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-016-3639-2
更新日期：2016-12-01 00:00:00
abstract：INTRODUCTION:Response rates to systemic chemotherapy for patients who have failed irinotecan-based chemotherapy for liver-dominant metastatic colorectal cancer range between 10 and 18 % with overall survival between 7 and 9 months. The aim of this study was to assess the efficacy and safety of hepatic arterial irinotec...
journal_title：World journal of surgery
pub_type： 杂志文章,多中心研究
doi：10.1007/s00268-015-3386-9
更新日期：2016-05-01 00:00:00
abstract：BACKGROUND:The long-term course after peptic ulcer perforation is unclear, but because the ulcer population is generally older and has concomitant disease, the long-term prognosis may be expected to be poor. METHODS:In a study based on prospective data collection, all patients with peptic ulcer perforation treated at ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9370-2
更新日期：2008-03-01 00:00:00
abstract：BACKGROUND:Exact tissue identification during parathyroidectomy is essential to successfully cure hyperparathyroidism. PTH level determination from tissue aspirates has been advocated as a "biochemical frozen section" for parathyroid tissue identification. We investigated the sensitivity and specificity of this method ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0351-5
更新日期：2010-03-01 00:00:00
abstract：:Recent collective reviews have outlined when and how surgeons should treat patients with bile duct injuries after laparoscopic cholecystectomy (LC). However, little is described about other injuries combined with bile duct injuries, for example, hepatic arterial injury and secondary biliary cirrhosis. Fifteen patients...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-001-0120-6
更新日期：2001-10-01 00:00:00
abstract：BACKGROUND AND AIMS:A variety of minimally invasive techniques have been proposed to replace open surgery for the treatment of infected pancreatic necrosis (IPN). In this study, we evaluate the feasibility and safety of the stent-assisted percutaneous endoscopic necrosectomy (SAPEN) procedure. METHODS:Data were collec...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-018-04878-9
更新日期：2019-04-01 00:00:00
abstract：INTRODUCTION:Hypoxic stress is a feature of rapidly growing thyroid tumours. Cancer progression is thought to be driven by a small population of tumour cells possessing stem cell properties. Hypoxia-inducible factors (HIFs) are important mediators of hypoxia. Both HIF-1alpha and HIF-2alpha have been reported to be expr...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-017-4331-x
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Complications are important indicators of immediate postoperative outcomes. The Clavien-Dindo classification (CDC) is a widely used index for the classification of surgical complications. More recently, the comprehensive complication index (CCI) has also been introduced for classifying postoperative complica...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-020-05859-7
更新日期：2021-03-01 00:00:00
abstract：BACKGROUND:We describe a new technique of segment-based liver resection by inserting a 6 French balloon catheter into the portal vein via a branch of the superior mesenteric vein. MATERIALS AND METHODS:The catheter was guided into the relevant portal branch supplying the liver segment that contained the tumor. Injecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-007-9043-1
更新日期：2007-06-01 00:00:00
abstract：:One hundred years ago, Edoardo Bassini said: "L'ernia é una malattia meccanica." Before that, Ambroise Paré (1598) and Joseph-Pierre Desault (1798) asserted the mechanical nature of strangulation. Beside strangulation, the most serious of all complications even today, I have studied huge hernias, which are natural com...
journal_title：World journal of surgery
pub_type： 杂志文章,评审
doi：10.1007/BF01658869
更新日期：1989-09-01 00:00:00
abstract：BACKGROUND:Hepatocellular carcinoma (HCC) is the most common primary liver cancer, causing approximately 660,000 deaths worldwide annually. The preferred treatment of HCC is surgical resection or orthotopic liver transplantation (OLT) for patients meeting specific criteria. For patients outside these criteria, options ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-010-0954-x
更新日期：2011-08-01 00:00:00
abstract：:Met protein is a tyrosine kinase receptor for hepatocyte growth factor (HGF). c-Met has morphogenic, mitogenic, and motogenic properties and is overexpressed in many solid tumors. We studied c-met mRNA and protein expression in papillary thyroid carcinomas and nonneoplastic thyroid tissue. The c-met mRNA was detected ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002680020167
更新日期：2001-05-01 00:00:00
abstract：BACKGROUND:Nonoperative management (NOM) of kidney gunshot injuries as an alternative to surgical exploration is rarely reported. The aim of this study was to assess the feasibility and safety of selective NOM of such injuries. METHODS:A 4-year prospective study was conducted that included all patients admitted to a L...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-008-9888-y
更新日期：2009-03-01 00:00:00
abstract：BACKGROUND:It has been suggested that gender and age could be factors that influence the likelihood of success following antireflux surgery, and our anecdotal impression has been that the outcome following Nissen fundoplication in older women is often disappointing. If correct, characterization of the extent of any dif...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-009-0216-y
更新日期：2009-12-01 00:00:00
abstract：BACKGROUND:Single-incision laparoscopic colorectal surgery (SILS) suggests a promising alternative to conventional laparoscopic surgery. In this report we describe our initial experience with SILS for both right hemicolectomies and anterior resections. METHODS:Between June 2009 and May 2010, SILS was performed for 32 ...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s00268-011-0989-7
更新日期：2011-04-01 00:00:00
abstract：:We reviewed our experience with 34 patients with metastatic endocrine tumors (METs) who were treated by different modalities. Eight patients were treated by chemotherapy or chemoembolization because of stable disease or surgical contraindications. Seventeen patients underwent curative or cytoreductive surgical resecti...
journal_title：World journal of surgery
pub_type： 杂志文章
doi：10.1007/s002689900138
更新日期：1996-09-01 00:00:00
