Glutathione stimulates A549 cell proliferation in glutamine-deficient culture: the effect of glutamate supplementation.

abstract：:Mouse keratinocytes are induced to differentiate in vitro by elevating the level of extracellular calcium from 0.05 mM, where keratinocytes express a basal cell phenotype, to greater than 0.10 mM, where they express the differentiated phenotype. This process has been associated with a rapid, sustained increase in inos...

journal_title：Journal of cellular physiology

authors： Lee E,Yuspa SH

更新日期：1991-07-01 00:00:00

abstract：:Wnt5a, a member of the noncanonical Wnt proteins, is known to play important roles in the development of various organs and in postnatal cell functions. However, little is known about the effects of Wnt5a on human periodontal ligament (PDL) cells. In this study, we examined the localization and potential function of W...

journal_title：Journal of cellular physiology

authors： Hasegawa D,Wada N,Maeda H,Yoshida S,Mitarai H,Tomokiyo A,Monnouchi S,Hamano S,Yuda A,Akamine A

更新日期：2015-11-01 00:00:00

abstract：:The etiology of endometriosis, a gynecological disease characterized by the presence of endometrial glands and stroma outside the uterine cavity, is still unknown. Our research group has recently demonstrated the presence of ectopic endometrium in human female fetuses at different gestational ages. In this manuscript ...

journal_title：Journal of cellular physiology

authors： Signorile PG,Baldi F,Bussani R,Viceconte R,Bulzomi P,D'Armiento M,D'Avino A,Baldi A

更新日期：2012-04-01 00:00:00

abstract：:Ménière's disease (MD) is a disorder of the inner ear characterized by an insidious onset and aspecific symptoms, such as dizziness, vertigo, tinnitus, and hearing loss, that may become very debilitating. The presence of endolymphatic hydrops is a common feature in MD patients, but the pathophysiology is still largely...

journal_title：Journal of cellular physiology

authors： Chiarella G,Saccomanno M,Scumaci D,Gaspari M,Faniello MC,Quaresima B,Di Domenico M,Ricciardi C,Petrolo C,Cassandro C,Costanzo FS,Cuda G,Cassandro E

更新日期：2012-01-01 00:00:00

abstract：:Neuropathological disorders are increasingly associated with dysfunctions in neuronal membrane traffic and autophagy, with defects among members of the Rab family of small GTPases implicated. Mutations in the human Xq28 localized gene RAB39B have been associated with X-linked neurodevelopmental defects including macro...

journal_title：Journal of cellular physiology

authors： Tang BL

更新日期：2021-03-01 00:00:00

abstract：:Calreticulin is an ER calcium-storage protein, which influences gene expression and cell adhesion. In this study, we analysed the differences in adhesive properties of calreticulin under- and overexpressing fibroblasts in relation to the calmodulin- and calcium/calmodulin-dependent kinase II (CaMK II)-dependent signal...

journal_title：Journal of cellular physiology

authors： Szabo E,Papp S,Opas M

更新日期：2007-10-01 00:00:00

abstract：:Galpha(i)-coupled receptors comprise a diverse family of receptors that induce transformation by largely unknown mechanisms. We previously found that the Galpha(i)-coupled dopamine-D2short (D2S) receptor transforms Balb-D2S cells via Gαi3. To identify new Gαi effectors, a yeast two-hybrid screen was done using constit...

journal_title：Journal of cellular physiology

authors： Laliberté B,Wilson AM,Nafisi H,Mao H,Zhou YY,Daigle M,Albert PR

更新日期：2010-11-01 00:00:00

abstract：:The coupled action of the Na(+)/H(+) exchanger NHE1 and the HCO3(-)/Cl(-) exchanger AE2 constitutes the principal mechanism for acute correction of decreased cell volume in mammalian somatic cells, while, when acting separately, they regulate intracellular pH. It was previously found that AE2 becomes inactivated durin...

journal_title：Journal of cellular physiology

authors： Zhou C,Fitzharris G,Alper SL,Baltz JM

更新日期：2013-10-01 00:00:00

abstract：:Suppression of PKC activity can selectively induce apoptosis in cells expressing a constitutively activated p21Ras protein. We demonstrate that continued expression of p21Ras activity is required in PKC-mediated apoptosis because farnesyltransferase inhibitors abrogated the loss of viability in p21Ras-transformed cell...

journal_title：Journal of cellular physiology

authors： Liou JS,Chen JS,Faller DV

更新日期：2004-02-01 00:00:00

abstract：:Arsenicosis induced by chronic exposure to arsenic is recognized as one of the main damaging effects on public health. Exposure to arsenic can cause hepatic fibrosis, but the molecular mechanisms by which this occurs are complex and elusive. It is not known if miRNAs are involved in arsenic-induced liver fibrosis. We ...

journal_title：Journal of cellular physiology

authors： Xue J,Xiao T,Wei S,Sun J,Zou Z,Shi M,Sun Q,Dai X,Wu L,Li J,Xia H,Tang H,Zhang A,Liu Q

更新日期：2021-01-22 00:00:00

abstract：:Minute virus of mice (MVM), a non-defective parvovirus, has been shown to infect cultures of non-pluripotent differentiated teratocarcinoma-derived cells, but pluripotent (and "nullipotent") embryonal carcinoma cells derived from the same teratocarcinoma resist MVN infection. Somatic cell hybrids between an embryonal ...

journal_title：Journal of cellular physiology

authors： Miller RA,Ward DC,Ruddle FH

更新日期：1977-06-01 00:00:00

abstract：:Endothelial cells are known to bind to laminin, and two peptides derived from the laminin A (CTFALRGDNP) and B1 (CDPGYIGSR) chains block the capillary-like tube formation on a laminin-rich basement membrane matrix, Matrigel. In the present study, we have used various in vitro and in vivo assays to investigate the angi...

journal_title：Journal of cellular physiology

authors： Grant DS,Kinsella JL,Fridman R,Auerbach R,Piasecki BA,Yamada Y,Zain M,Kleinman HK

更新日期：1992-12-01 00:00:00

abstract：:Tenascin-C, a six-armed extracellular matrix glycoprotein, is expressed in a temporally and spatially restricted pattern during carcinogenesis and invasion or metastasis of carcinoma cells in association with stromal-epithelial interactions. The human epidermoid carcinoma-derived cell lines, A431 and HEp-2, which do n...

journal_title：Journal of cellular physiology

authors： Sakai T,Ohta M,Furukawa Y,Saga Y,Aizawa S,Kawakatsu H,Saito M

更新日期：1995-10-01 00:00:00

abstract：:Cells are quite sensitive to a change of the extracellular pH and respond to it through detection of the H+/HCO3- level in extracellular fluid. However, little is known about molecular details induced by acidosis, such as intracellular pathways and gene expression. Here we describe properties of gene expression, prote...

journal_title：Journal of cellular physiology

authors： Shimokawa N,Kumaki I,Qiu CH,Ohmiya Y,Takayama K,Koibuchi N

更新日期：2005-10-01 00:00:00

abstract：:Incubation of cultured bovine pulmonary artery endothelial cells with 200 microM of 3-isobutyl-1-methylxanthine (IBMX) for 24 hr produced a five- to tenfold increase in cellular angiotensin converting enzyme activity (ACE) above that of untreated control cells. A lesser increase was observed in medium ACE. Other methy...

journal_title：Journal of cellular physiology

authors： Dasarathy Y,Fanburg BL

更新日期：1988-10-01 00:00:00

abstract：:It is known that down-regulation of cell surface platelet-derived growth factor (PDGF) receptors accompanies transformation by SV40. In this work human embryonic lung fibroblasts were used as a model system to study the effects of SV 40 on PDGF receptor expression. It is shown that transformation by SV 40 early region...

journal_title：Journal of cellular physiology

authors： Wang JL,Nistér M,Bongcam-Rudloff E,Pontén J,Westermark B

更新日期：1996-01-01 00:00:00

abstract：:Epithelial cells are important components of the thymus microenvironment and are involved in thymocyte differentiation. The production and secretion of sulfated glycosaminoglycans by these cells grown in culture were investigated using labeling with radioactive 35S-Na2SO4 and 3H-glucosamine. The major glycosaminoglyca...

journal_title：Journal of cellular physiology

authors： Werneck CC,Oliveira-Dos-Santos AJ,Silva LC,Villa-Verde DM,Savino W,Mourão PA

更新日期：1999-01-01 00:00:00

abstract：:Regulation of lipid synthesis from acetate in human diploid fibroblast cultures has been studied at various passage levels and at different stages of cell growth. When cultures were transferred to lipid free medium, a stimulation of [14C]acetate incorporation into lipid occurred within three to six hours after removal...

journal_title：Journal of cellular physiology

authors： Howard BV,Howard WJ,Kefalides NA

更新日期：1976-10-01 00:00:00

abstract：:A rat pheochromocytoma cell line (PC12 cells) was used as a model to investigate the role of calmodulin and its multiple mRNAs in NGF-induced neuronal differentiation. The effect of NGF on the degree of differentiation was assayed using a simple differentiation scoring system. Significant increases in the differentiat...

journal_title：Journal of cellular physiology

authors： Bai G,Weiss B

更新日期：1991-12-01 00:00:00

abstract：:Apelin is an endogenous ligand of seven-transmembrane G protein-coupled receptor APJ. Apelin and APJ are distributed in various tissues, including the heart, lung, kidney, and even in tumor tissues. Studies show that apelin mRNA is highly expressed in the inner stripe of kidney outer medulla, which plays an important ...

journal_title：Journal of cellular physiology

authors： Huang Z,Wu L,Chen L

更新日期：2018-05-01 00:00:00

abstract：:In novel coronavirus disease 2019 (COVID-19), the increased frequency and overactivation of T helper (Th) 17 cells and subsequent production of large amounts of proinflammatory cytokines result in hyperinflammation and disease progression. The current study aimed to investigate the therapeutic effects of nanocurcumin ...

journal_title：Journal of cellular physiology

authors： Tahmasebi S,El-Esawi MA,Mahmoud ZH,Timoshin A,Valizadeh H,Roshangar L,Varshoch M,Vaez A,Aslani S,Navashenaq JG,Aghebati-Maleki L,Ahmadi M

更新日期：2020-12-28 00:00:00

abstract：:Incubation of isolated rat soleus and EDL muscles in the presence of 10 mM leucine resulted in a decreased proteolytic rate as measured by the release of tyrosine into the incubation medium. The effect of this branched-chain amino acid (BCAA) is associated with a decreased activity of the lysosomal proteases and a dec...

journal_title：Journal of cellular physiology

authors： Busquets S,Alvarez B,Llovera M,Agell N,López-Soriano FJ,Argilés JM

更新日期：2000-09-01 00:00:00

abstract：:Spiral artery remodeling at the maternal-fetal interface is crucial for successful pregnancy and requires the interaction between the first trimester trophoblast and the endothelial cells of the maternal vessels. However, the precise mechanism of this dialog has yet to be determined. The current study investigated whe...

journal_title：Journal of cellular physiology

authors： Beltrame JS,Scotti L,Sordelli MS,Cañumil VA,Franchi AM,Parborell F,Ribeiro ML

更新日期：2019-05-01 00:00:00

abstract：:Lipocalin-2 (LCN2) is a protein largely expressed in many tissues, associated with different biological phenomena such as cellular differentiation, inflammation and cancer acting as a survival/apoptotic signal. We found that LCN2 was expressed during osteoblast differentiation and we generated transgenic (Tg) mice ove...

journal_title：Journal of cellular physiology

authors： Costa D,Lazzarini E,Canciani B,Giuliani A,Spanò R,Marozzi K,Manescu A,Cancedda R,Tavella S

更新日期：2013-11-01 00:00:00

abstract：:Non-small-cell lung cancer (NSCLC) remains the leading cause of cancer death worldwide. As a platinum-based chemotherapeutic drug, cisplatin has been used for over 30 years in NSCLC treatment while its effects are diminished by drug resistance. Therefore, we aimed to study the potential role of UCA1 in the development...

journal_title：Journal of cellular physiology

authors： Li C,Fan K,Qu Y,Zhai W,Huang A,Sun X,Xing S

更新日期：2020-04-01 00:00:00

abstract：:Atherosclerosis is one of the leading causes of morbidity and mortality, mainly due to the immune response triggered by the recruitment of monocytes/macrophages in the artery wall. Accumulating evidence have shown that matrix stiffness and oxidized low-density lipoproteins (ox-LDL) play important roles in atherosclero...

journal_title：Journal of cellular physiology

authors： Li J,Wang S,Li Y,Zhang N,Gribskov M,Zhang X,Lin M,Shao D,Zhang C,Dai L,Qin C,Duan X,Li J,Xu F,Yang H

更新日期：2020-09-01 00:00:00

abstract：:The effect of hypoxia on 3T3-L1 cell differentiation was examined in confluent cultures incubated with differentiation medium (DM) followed by incubation in growth medium (GM). Control cultures remained in GM throughout the incubation period. Eight days after the incubation, cells were assessed either for changes in m...

journal_title：Journal of cellular physiology

authors： Sahai A,Patel MS,Zavosh AS,Tannen RL

更新日期：1994-07-01 00:00:00

abstract：:Ethanol induces neuronal cell injury and death by dysregulating several signaling events that are controlled, in part, by activation of MAPK/ERK1/2 and/or inactivation of its corresponding phosphatase, PP1. Recently, we have purified a novel protein of 38 kDa in size, p38SJ, from a callus culture of Hypericum perforat...

journal_title：Journal of cellular physiology

authors： Amini S,Merabova N,Khalili K,Darbinian N

更新日期：2009-12-01 00:00:00

abstract：:Exposure of neutrophils to a variety of agonists including soluble chemoattractant peptides and cytokines results in degranulation and activation of the oxidative burst (effector functions) that are required for bacterial killing. At present, the signaling pathways regulating these important functions are incompletely...

journal_title：Journal of cellular physiology

authors： Sue-A-Quan AK,Fialkow L,Vlahos CJ,Schelm JA,Grinstein S,Butler J,Downey GP

更新日期：1997-07-01 00:00:00

abstract：:Phospholipase A2 (PLA2) is pivotal in the rapid membrane-mediated actions of 1,25-dihydroxyvitamin D3 [1alpha,25(OH)2D3]. Microarray analysis indicated that PLA2 activating protein (PLAA) mRNA is upregulated 6-fold before rat growth plate cells exhibit 1alpha,25(OH)2D3-dependent protein kinase C (PKC) increases, sugge...

journal_title：Journal of cellular physiology

authors： Schwartz Z,Graham EJ,Wang L,Lossdörfer S,Gay I,Johnson-Pais TL,Carnes DL,Sylvia VL,Boyan BD

更新日期：2005-04-01 00:00:00