Abstract:
OBJECTIVES:To evaluate prospectively the impact of subtle tubal disorders on GIFT pregnancy rates in women with pelvic endometriosis. DESIGN:A prospective comparison of pregnancy rates in different stages of endometriosis while controlling for the presence of tubal abnormalities. INTERVENTIONS:A total of 146 patients with endometriosis underwent 201 GIFT procedures. During laparoscopy special attention was brought to the fallopian tubes and any anatomical disorders were recorded. Tubal abnormalities included tubal sacculations, diverticulae, convolutions, phimosis, fimbrial agglutination, and peritubal adhesions. Best tube was considered in the final analysis. RESULTS:The presence of tubal abnormalities significantly lowered the pregnancy rates in all stages of endometriosis. When we controlled for age, semen characteristics, number of mature oocytes transferred, and tubal status, the extent of anatomical tubal disorders was the most important prognostic factor in determining pregnancy outcome. CONCLUSION:The extent of tubal abnormalities rather than the stage of endometriosis seems to be an important prognostic factor in determining GIFT pregnancy rates. Couples should be counseled accordingly and accurate prognostic parameters should be explained before enrollment in a GIFT program.
journal_name
Fertil Steriljournal_title
Fertility and sterilityauthors
Fakih H,Marshall Jdoi
10.1016/s0015-0282(16)57007-1subject
Has Abstractpub_date
1994-10-01 00:00:00pages
799-801issue
4eissn
0015-0282issn
1556-5653pii
S0015-0282(16)57007-1journal_volume
62pub_type
杂志文章abstract:OBJECTIVE:Immunobead testing (IBT), the current standard for antisperm antibody detection, is time consuming and somewhat subjective. To overcome these limitations and maintain accuracy, we studied an immunofluorescent assay using flow cytometry. DESIGN:A validation study comparing flow cytometry to IBT in the detecti...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1995-04-01 00:00:00
abstract:OBJECTIVE:To evaluate the phenotype, proliferative, and differentiation capacities in vitro of stromal cells derived from peritoneal, ovarian, and deeply infiltrating endometriosis. DESIGN:Experimental study using phase contrast microscopy, immunocytochemistry, and functional bioassays. SETTING:University-based labor...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.08.046
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To report an unusual case of embryo implantation and superfetation. DESIGN:Retrospective case analysis. SETTING:Oak Brook Fertility Center. PATIENT(S):A 41-year-old woman underwent two consecutive ovarian stimulation cycles interrupted by a normal menstrual period. Ovulation and implantation occurred durin...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)00244-6
更新日期:1997-09-01 00:00:00
abstract::One hundred four consecutive men who underwent a semen analysis as part of their infertility evaluation were assayed for sperm-associated immunoglobulin (Ig) and the third component of complement (C3). Sixteen (15%) of the 104 men had increased IgG, and 10 (12%) of 86 men tested had increased IgA on their sperm; howev...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1983-04-01 00:00:00
abstract::The circulating levels of leptin and neuropeptide Y, which are both involved in the control of feeding and reproduction, were measured in amenorrheic and normal cycling highly trained women athletes, and in normal cycling sedentary controls. Leptin showed similar low values in all athletes, whereas neuropeptide Y leve...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2005.08.041
更新日期:2006-03-01 00:00:00
abstract:OBJECTIVE:To extend and confirm earlier observations that serial CA-125 determinations appear to have prognostic value in some infertile women with surgically treated endometriosis using a new automated enzyme immunoassay. DESIGN:A prospective consecutive case series. SETTING:A university-based tertiary practice. PA...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:
更新日期:1995-08-01 00:00:00
abstract:OBJECTIVE:To compare the efficacy of a sequential step-up/step-down protocol with the conventional low dose step-up and the step-down regimens in patients with polycystic ovary syndrome (PCOS) undergoing IVF. DESIGN:Prospective randomized study. SETTING:Private fertility clinic. PATIENT(S):Two hundred twenty-five, 3...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2007.06.080
更新日期:2008-09-01 00:00:00
abstract:OBJECTIVE:To present two cases of ectopic twin pregnancy in a Cesarean section scar following IVF-embryo transfer. DESIGN:Case report. SETTING:Tertiary referral case center. PATIENT(S):Two women who had ectopic twin pregnancy in a Cesarean section scar, in both cases following IVF and embryo transfer. INTERVENTION(...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.11.091
更新日期:2008-11-01 00:00:00
abstract:OBJECTIVE:To study the role of a synthetic insulin-like growth factor-I receptor (IGF-IR) antagonist, picropodophyllin, for mouse preimplantation embryo development in vivo and in vitro. DESIGN:In vitro and in vivo study. SETTING:Hospital-based research unit. ANIMALS:FVB/N mice and mouse embryos. INTERVENTION(S):Th...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.12.044
更新日期:2010-05-15 00:00:00
abstract:OBJECTIVE:To measure activin A concentrations in uterine washing fluid collected from women with couple infertility undergoing intrauterine insemination (IUI). DESIGN:Retrospective case-control study. SETTING:Tertiary university center for women's care. PATIENT(S):Fifty women, of whom 25 became pregnant after up to ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.12.125
更新日期:2010-05-01 00:00:00
abstract:OBJECTIVE:To study the use of the aromatase inhibitor letrozole for treatment of ectopic pregnancy compared with methotrexate. DESIGN:Nonrandomized prospective cohort study. SETTING:University hospital. PATIENT(S):A series of 42 consecutive patients with undisturbed ectopic pregnancy. INTERVENTION(S):Counseling on ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2020.04.001
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:To develop and validate a specific simple measure of insulin sensitivity using oral glucose tolerance test (OGTT) values for lean polycystic ovary syndrome (PCOS) women. DESIGN:Retrospective study. SETTING:Gynecologic Outpatient Clinic of University Hospital, affiliated with Unit of Gynecologic Endocrinolog...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2014.04.004
更新日期:2014-07-01 00:00:00
abstract:OBJECTIVE:To determine whether high levels of interleukin (IL)-10 can attenuate the production of tumor necrosis factor (TNF)-alpha-induced proinflammatory cytokines in endometriotic stromal cells. DESIGN:Prospective study. SETTING:Department of Ob/Gyn, Tottori University, Japan. PATIENT(S):Thirty-five patients with...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.04.052
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:Potential reparation of sperm DNA fragmentation in the oocyte may disturb any relationship between DNA-damaged sperm and the implantation ability of resulting embryos. To rule out this factor, we analyzed the consequences of sperm DNA fragmentation on IVF-ET outcome in women with healthy ovarian function. DE...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/j.fertnstert.2007.02.022
更新日期:2008-01-01 00:00:00
abstract:OBJECTIVE:To compare obstetric and perinatal outcomes of singleton pregnancies resulting from embryos incubated in a time-lapse system (TLS) with those of embryos grown in standard IVF incubators (SI). DESIGN:Retrospective description of a cohort of patients who conceived during a randomized, controlled trial. SETTIN...
journal_title:Fertility and sterility
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.fertnstert.2017.06.031
更新日期:2017-09-01 00:00:00
abstract::A number of patients who have involuntary infertility show sperm antibodies in the blood serum, as detected by two quite different methods of spermagglutination. These techniques are the Kibrick method (gelatin agglutination test) and the F-D method (tube-slide agglutination test). By the former technique, the sera of...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)43158-4
更新日期:1978-03-01 00:00:00
abstract:OBJECTIVE:To study the morphological changes of apoptotic oocytes, and rates of in vitro maturation and apoptosis of human oocytes in relation to age. DESIGN:Prospective comparative study. SETTING:Reproductive medicine center. PATIENT(S):Women undergoing surgery for ovarian cysts. INTERVENTION(S):Oocytes were incub...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01597-1
更新日期:2000-12-01 00:00:00
abstract::Transferrin and somatomedin C receptors (TFr and SMCr) were studied in human ovaries by immunostaining using monoclonal antisera. The oocyte of evoluting follicles was intensely positive for both types of receptors, but this positivity decreases in large follicles. An evident positivity for both TFr and SMCr was shown...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)59533-8
更新日期:1987-11-01 00:00:00
abstract:OBJECTIVE:To determine accumulated conception and live birth rates in ovum donation. DESIGN:Retrospective study from a computer database. Pregnancies with one gestational sac observed by ultrasound have been included as conceptional cycles and pregnancies that resulted in one live child were recorded for the analysis ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(97)81372-6
更新日期:1997-04-01 00:00:00
abstract:OBJECTIVE:To determine whether the known inactivating FSH receptor gene mutations are present in Japanese women with secondary amenorrhea because of premature ovarian failure (POF) and polycystic ovary syndrome (PCOS). DESIGN:Clinical and molecular studies. SETTING:An outpatient clinic in a university hospital. PATI...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(00)01673-3
更新日期:2001-01-01 00:00:00
abstract:OBJECTIVE:To analyze sonographically the endometrium in patients undergoing controlled ovarian stimulation with menotropins in order to determine the significance of endometrial pattern and thickness on pregnancy rate. DESIGN:This is a prospective, nonrandomized study comparing pregnancy rates in patients with hyperec...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(16)58447-7
更新日期:1996-08-01 00:00:00
abstract:OBJECTIVE:To investigate the relationship between follicular blood flow and the follicular fluid vascular endothelial growth factor (VEGF) and nitric oxide (NO) concentrations and to determine which factor might be a better predictor of the outcome of IVF-ET. DESIGN:Prospective study. SETTING:Academic research labora...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2004.02.120
更新日期:2004-09-01 00:00:00
abstract::In 80 normal puerperae, serum follicle-stimulating hormone (FSH), luteinizing hormone (LH), including human chorionic gonadotropin (hCG/LH), and prolactin (PRL) levels were evaluated 6 to 29 hours after vaginal delivery. In these puerperae, PRL levels were higher and FSH levels were lower than in menstruating women; h...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/s0015-0282(16)46103-0
更新日期:1982-03-01 00:00:00
abstract:OBJECTIVE:To describe a rare case of a cervico-isthmic pregnancy with anterior placenta percreta that was treated at 34 weeks of gestation by removing the placenta and the attached uterine wall in one piece. DESIGN:Case report. SETTING:Tertiary university hospital. PATIENT(S):A 32-year-old woman was diagnosed with a...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2007.06.007
更新日期:2008-06-01 00:00:00
abstract::Because spermatocyte meiotic error results in embryonic sex chromosomal aneuploidy, it is speculated that teratospermia correlates with increased embryonic sex chromosomal abnormalities. Our findings contradict this theory, suggesting that morphology does not correlate with sex chromosomal genotype. ...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2009.07.1006
更新日期:2010-02-01 00:00:00
abstract::A randomized prospective study was performed to compare the effects of a midfundal versus a deep fundal transfer technique on subsequent intrauterine and ectopic PRs after IVF. The clinical intra-uterine PR after the deep fundal transfer was 12.4% per cycle with a 1.5% ectopic PR (which represented 12.2% of the pregna...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1993-11-01 00:00:00
abstract:OBJECTIVE:To assess the prevalence of infectious complications and the protective effect of prophylactic antibiotic treatment after diagnostic office hysteroscopy in asymptomatic, infertile patients with normal results from transvaginal sonography. DESIGN:Recording of infectious complications after routine hysteroscop...
journal_title:Fertility and sterility
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1016/j.fertnstert.2010.08.031
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:To ascertain whether obstetric, gynecologic, or congenital variables affect implantation efficiency or eventual delivery in donor oocyte recipients. DESIGN:Clinical study. SETTING:Academic tertiary care infertility clinic. PATIENT(S):A total of 370 recipients. INTERVENTION(S):Fresh ET following oocyte don...
journal_title:Fertility and sterility
pub_type: 临床试验,杂志文章
doi:10.1016/s0015-0282(98)00420-8
更新日期:1999-01-01 00:00:00
abstract:OBJECTIVE:To determine the effect of P on nitric oxide synthase (NOS) expression in human endometrial epithelial cells. DESIGN:Laboratory-based study. SETTING:University-based research institute. PATIENT(S):None. INTERVENTION(S):The effect of P on the expression of NOS protein isoforms was examined in an in vitro p...
journal_title:Fertility and sterility
pub_type: 杂志文章
doi:10.1016/j.fertnstert.2008.05.019
更新日期:2009-05-01 00:00:00
abstract:OBJECTIVE:To develop a consensus regarding the need for luteal phase support during assisted reproductive technology (ART), and to establish the optimal compound and route of administration for this purpose. DESIGN:Review of the published literature on luteal phase support. PATIENT(S):Women undergoing assisted reprod...
journal_title:Fertility and sterility
pub_type: 杂志文章,评审
doi:10.1016/s0015-0282(01)02961-2
更新日期:2002-02-01 00:00:00