Transferrin and somatomedin C receptors in the human ovarian follicles.

Abstract:

:Transferrin and somatomedin C receptors (TFr and SMCr) were studied in human ovaries by immunostaining using monoclonal antisera. The oocyte of evoluting follicles was intensely positive for both types of receptors, but this positivity decreases in large follicles. An evident positivity for both TFr and SMCr was shown in granulosa cells of evoluting follicles. However, not all of these cells were equally immunoreactive. An intense positivity was present in the developing thecal cells of early cavitary follicles as well as in thecal cells of follicles of medium and large size (greater than 6 mm) and in some cells of involuting follicles in initial atresia. These results seem to demonstrate that TFr and SMCr are present in different cellular components of the human developing and early involuting follicles.

journal_name

Fertil Steril

journal_title

Fertility and sterility

authors

Balboni GC,Vannelli GB,Barni T,Orlando C,Serio M

doi

10.1016/s0015-0282(16)59533-8

subject

Has Abstract

pub_date

1987-11-01 00:00:00

pages

796-801

issue

5

eissn

0015-0282

issn

1556-5653

pii

S0015-0282(16)59533-8

journal_volume

48

pub_type

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