Herpes zoster: a comparative study of general practitioner and patient experience.

abstract：:Propranolol has recently been shown to produce some impairment of psychomotor performance in human volunteers. This beta-blocking compound, however, is lipophilic and readily penetrates the blood-brain barrier to gain access to the central nervous system. Acebutolol has a lower lipid solubility. A study was carried ou...

journal_title：Current medical research and opinion

authors： Broadhurst AD

更新日期：1980-01-01 00:00:00

abstract：OBJECTIVE:To quantify changes in clinical and cost outcomes associated with increasing levels of body mass index (BMI) in a US setting. RESEARCH METHODS AND PROCEDURES:A semi-Markov model was developed to project and compare life expectancy (LE), quality-adjusted life expectancy (QALE) and direct medical costs associa...

journal_title：Current medical research and opinion

authors： Tucker DM,Palmer AJ,Valentine WJ,Roze S,Ray JA

更新日期：2006-03-01 00:00:00

abstract：BACKGROUND:Triptans are not identical and migraine sufferers respond differently to different triptans. Few studies have evaluated the efficacy of switching triptans in migraine patients who have shown poor response to another agent. OBJECTIVE:To investigate the efficacy and tolerability of almotriptan 12.5 mg in pati...

journal_title：Current medical research and opinion

authors： Diener HC

更新日期：2005-10-01 00:00:00

abstract：OBJECTIVE:Neurosurgery often requires skull immobilization with a Mayfield clamp, which often causes brief intense nociceptive stimulation, hypertension and tachycardia. Blunting this response may help prevent increased intracranial pressure, cerebral aneurysm or vascular malformation rupture, and/or myocardial stress....

journal_title：Current medical research and opinion

authors： Berger M,Philips-Bute B,Guercio J,Hopkins TJ,James ML,Borel CO,Warner DS,McDonagh DL

更新日期：2014-02-01 00:00:00

abstract：:The therapeutic efficacy of cimetidine given as 400 mg twice daily was compared to that of cimetidine given as 1.0 g daily in 4 divided doses (200 mg 3-times daily and 400 mg at night) in two groups of 25 patients (total 50 patients) with active duodenal ulceration. After 4 weeks, healing rates of 72% and 76%, respect...

journal_title：Current medical research and opinion

authors： Papadopoulos C,Kalantzis N,Rekoumis G,Kanaghinis T

更新日期：1985-01-01 00:00:00

abstract：OBJECTIVE:To assess the effect of an individualized genomic classifier (GC) test, for predicting metastasis following radical prostatectomy (RP), on urologists' adjuvant treatment decisions when caring for high-risk patients. PATIENTS AND METHODS:Data were submitted by US board-certified urologists in community practi...

journal_title：Current medical research and opinion

authors： Michalopoulos SN,Kella N,Payne R,Yohannes P,Singh A,Hettinger C,Yousefi K,Hornberger J,PRO-ACT Study Group.

更新日期：2014-08-01 00:00:00

abstract：OBJECTIVE:Implantation of bone marrow mononuclear cells (BM-MNCs), including endothelial progenitor cells, into ischemic lower limbs has been shown to improve symptoms in patients with peripheral arterial diseases (PAD). This study investigated whether BM-MNC implantation (BMI) is also effective for the ischemic hands ...

journal_title：Current medical research and opinion

authors： Koshikawa M,Shimodaira S,Yoshioka T,Kasai H,Watanabe N,Wada Y,Seto T,Fukui D,Amano J,Ikeda U

更新日期：2006-04-01 00:00:00

abstract：BACKGROUND:Breast cancer cells can develop resistance to standard hormonal treatment and chemotherapy with the activation of the mTOR pathway; this is supported by results of preclinical and clinical studies. In clinical trials, the addition of everolimus to hormonal treatment or anti-HER2 treatment improved the outcom...

journal_title：Current medical research and opinion

authors： Sendur MA,Zengin N,Aksoy S,Altundag K

更新日期：2014-01-01 00:00:00

abstract：:Atrial fibrillation (AF) is the most common sustained cardiac arrhythmia seen in clinical practice and has attracted much attention due to its association with a substantial mortality and morbidity, particularly from stroke, thromboembolism and heart failure. This Editorial Commentary provides a brief overview of the ...

journal_title：Current medical research and opinion

authors： Khoo CW,Lip GY

更新日期：2009-05-01 00:00:00

abstract：:An open, parallel-group study was carried out to compare the efficacy and tolerance of a sustained-release capsule formulation of tiaprofenic acid at a dosage of 600 mg once daily with standard 300 mg tiaprofenic acid tablets given twice daily. Four hundred and eighty-five general practice patients with rheumatic dise...

journal_title：Current medical research and opinion

authors： Phillips G,Selfridge DI,Hayes G,Rose CM

更新日期：1987-01-01 00:00:00

abstract：BACKGROUND:Over the last two decades the development and analysis of a number of registries have enhanced the knowledge of the epidemiology, presentation, natural history, and pathophysiology of pulmonary arterial hypertension (PAH). The understanding of the effectiveness of available treatments has also been greatly i...

journal_title：Current medical research and opinion

authors： Poscia R,Ghio S,D'Alto M,Vitulo P,Mulè M,Albera C,Parisi F,Badagliacca R,Fedele F,Vizza CD

更新日期：2014-12-01 00:00:00

abstract：OBJECTIVES:To report on the results of a recent large-scale, internet-based survey of the population, prevalence and attributes of pain experience in the United Kingdom (UK), France, Spain, Germany and Italy. METHODS:The results reported here are taken from the internet-based, 2008 National Health and Wellness Survey ...

journal_title：Current medical research and opinion

authors： Langley PC

更新日期：2011-02-01 00:00:00

abstract：:In a multi-centre study, the antidepressant efficacy and incidence of on-therapy events of trazodone (100 to 400 mg daily) and mianserin (30 to 120 mg daily) was compared using a double-blind pre-determined randomized parallel group design in depressed patients unresponsive to placebo after a 7-day screening period. O...

journal_title：Current medical research and opinion

authors： Bennie EH,Khan MC,Tyrer SP,Siddiqui U,Ankier SI

更新日期：1984-01-01 00:00:00

abstract：:A double-blind trial of methocarbamol versus placebo was carried out in 59 matched pairs of patients suffering from painful muscle spasm. Methocarbamol (1500 mg. q.d.s.) was found to be effective in approximately 60% of patients compared with 30% of patients receiving placebo (p less than 0.01). Side-effects were of a...

journal_title：Current medical research and opinion

authors： Valtonen EJ

更新日期：1975-01-01 00:00:00

abstract：BACKGROUND:As of 2012, nearly 10% of Americans had diabetes mellitus. People with diabetes are at approximately double the risk of premature death compared with those in the same age groups without the condition. While the prevalence of diabetes has risen across all racial/ethnic groups over the past 30 years, rates ar...

journal_title：Current medical research and opinion

authors： Ferdinand KC,Nasser SA

更新日期：2015-05-01 00:00:00

abstract：OBJECTIVE:Statins are hypothesized to have beneficial effects in asthma management through their pleiotropic anti-inflammatory effects. Several studies have examined this relationship, but have yielded conflicting results. This study investigates the effect of statin use on asthma-related hospitalizations and/or emerge...

journal_title：Current medical research and opinion

authors： Tse SM,Charland SL,Stanek E,Herrera V,Goldfarb S,Litonjua AA,Weiss ST,Wu AC

更新日期：2014-04-01 00:00:00

abstract：:Liver transplantation is currently a standard therapy for patients with end-stage liver diseases and hepatocellular carcinoma. Given that liver transplantation has undergone a thriving development in these decades, the survival rates after liver transplantation have markedly improved as a result of the critical advanc...

journal_title：Current medical research and opinion

authors： Mu J,Chen Q,Zhu L,Wu Y,Liu S,Zhao Y,Ma T

更新日期：2019-02-01 00:00:00

abstract：OBJECTIVES:Pioglitazone hydrochloride (Actos † ) and rosiglitazone maleate (Avandia ‡ ) are members of the thiazolidinedione (TZD) class of oral anti-diabetic drugs (OADs) and are used to treat type 2 diabetes mellitus (T2DM). Greater beneficial effects on lipids have been demonstrated with pioglitazone, however. Study...

journal_title：Current medical research and opinion

authors： Tunis SL,Minshall ME,St Charles M,Pandya BJ,Baran RW

更新日期：2008-11-01 00:00:00

abstract：BACKGROUND:Small cell lung cancer (SCLC) patients, who have achieved complete or partial response after chemotherapy, should be followed with prophylactic cranial irradiation (PCI). PCI for extrapulmonary small cell carcinoma (EPSCC) is not routinely recommended. The purpose of this review is to discuss all aspects of ...

journal_title：Current medical research and opinion

authors： Yazıcı O,Ozdemir NY,Sendur MA,Aksoy S,Zengin N

更新日期：2014-07-01 00:00:00

abstract：OBJECTIVE:The primary aim of this study was to compare the effect of colesevelam HCl in combination with ezetimibe to ezetimibe monotherapy on low-density lipoprotein cholesterol (LDL-C) levels in subjects with primary hypercholesterolemia. METHODS:Subjects with primary hypercholesterolemia (N = 86) were enrolled in a...

journal_title：Current medical research and opinion

authors： Bays H,Rhyne J,Abby S,Lai YL,Jones M

更新日期：2006-11-01 00:00:00

abstract：OBJECTIVE:We evaluated the clinical efficacy of sacubitril/valsartan in a group of ambulatory patients with heart failure (HF) with reduced ejection fraction (HFrEF) referred to our HF clinic. METHODS:Patients (n = 29; 72% males; mean age 76 years) with HFrEF in New York Heart Association (NYHA) classes II-III were in...

journal_title：Current medical research and opinion

authors： Cosentino ER,Degli Esposti D,Miceli R,Bentivenga C,Landolfo M,Fg Cicero A,Berardi E,Spinardi L,Magri G,Dugato V,Borghi C

更新日期：2019-03-01 00:00:00

abstract：OBJECTIVE:Evaluation of the safety and efficacy of insulin detemir (IDet) in the observational and non-interventional PREDICTIVE study. METHODS:A total of 2923 patients with type 1 or 2 diabetes on basal-bolus regimens were followed for 6 months: Group (1) NPH + human insulin (HI) bolus switching to IDet + analogue bo...

journal_title：Current medical research and opinion

authors： Hermansen K,Dornhorst A,Sreenan S

更新日期：2009-11-01 00:00:00

abstract：:Background: In routine clinical practice, the implantation of a drug-eluting stent (DES) versus a bare metal stent (BMS) for percutaneous coronary intervention (PCI) has been guided by criteria for appropriate use. The cost-effectiveness (CE) of adopting these guidelines, however, is not clear, and was investigated fr...

journal_title：Current medical research and opinion

authors： Ariyaratne TV,Ademi Z,Ofori-Asenso R,Huq MM,Duffy SJ,Yan BP,Ajani AE,Clark DJ,Billah B,Brennan AL,New G,Andrianopoulos N,Reid CM

更新日期：2020-03-01 00:00:00

abstract：:Neuroprotective agents inhibit reactions in the brain ischaemic injury cascade which lead to neuronal death. Gamma-aminobutyric acid (GABA) is a naturally occurring inhibitory neurotransmitter that increases chloride influx into the neuron and counteracts the toxic effects of glutamate. Clomethiazole is a GABA(A) agon...

journal_title：Current medical research and opinion

authors： Vaishnav A,Lutsep HL

更新日期：2002-01-01 00:00:00

abstract：BACKGROUND:Most studies investigating the benefits of statins have focused on North American and European populations. This study focuses on evaluating the lipid-lowering effects of rosuvastatin and atorvastatin in Asian patients. OBJECTIVES:The DIrect Statin COmparison of LDL-C Values: an Evaluation of Rosuvastatin t...

journal_title：Current medical research and opinion

authors： Zhu JR,Tomlinson B,Ro YM,Sim KH,Lee YT,Sriratanasathavorn C

更新日期：2007-12-01 00:00:00

abstract：:A single-blind, between-patient comparative study was carried out in general practice to assess the effectiveness of antacid plus antispasmodic combination tablets (240 mg dried aluminium hydroxide B.P., 144 mg magnesium hydroxide B.P.C., and 5 mg dicyclomine hydrochloride B.P.) and aluminium hydroxide B.P. tablets (5...

journal_title：Current medical research and opinion

authors： Kagan G,Rose R

更新日期：1977-01-01 00:00:00

abstract：BACKGROUND:Development of a second primary malignancy (SPM) after an index esophageal cancer is fairly rare, primarily due to decreased survival in patients with esophageal cancer. However, with advances in early detection and therapy, the number of long-term survivors is increasing, as is the incidence of SPMs in this...

journal_title：Current medical research and opinion

authors： Nandy N,Dasanu CA

更新日期：2013-09-01 00:00:00

abstract：:A national survey of psychotherapeutic drug use was carried out in the U.S.A. in 1979. Data were obtained from a probability sample (n = 3161) of adults in the general population, using a clinically-oriented interview lasting an average of 90 minutes. The data provide estimates of the prevalence of using anxiolytic an...

journal_title：Current medical research and opinion

authors： Mellinger GD,Balter MB,Uhlenhuth EH

更新日期：1984-01-01 00:00:00

abstract：OBJECTIVE:The prevalence of non-steroidal anti-inflammatory drug (NSAID) and concurrent gastroprotective agent (GPA) use in the US is not known. As such, the prevalence of GPA use among arthritis patients taking NSAIDs was examined. METHODS:Men and women aged ≥ 40 with self-reported arthritis and members of a web-base...

journal_title：Current medical research and opinion

authors： Coyne KS,Margolis MK,Cappelleri JC,Hsieh R,Essex MN,Park PW,Joshi AV

更新日期：2013-05-01 00:00:00

abstract：AIM:Non-peer-reviewed manuscripts posted as preprints can be cited in peer-reviewed articles, which has both merits and demerits. International Committee of Medical Journal Editors guidelines mandate authors to declare preprints at the time of manuscript submission. We evaluated the trends in pharma-authored research p...

journal_title：Current medical research and opinion

authors： Subramanian K,Nalli A,Senthil V,Bhat A

更新日期：2020-12-09 00:00:00