Lipid peroxidation and susceptibility of low-density lipoprotein to in vitro oxidation in hyperhomocysteinaemia.

abstract：BACKGROUND:It is well known that space travel cause post-flight orthostatic hypotension and it was assumed that autonomic cardiovascular control deteriorates in space. Lower body negative pressure (LBNP) was used to assess autonomic function of the cardiovascular system. METHODS:LBNP tests were performed on six crew-m...

journal_title：European journal of clinical investigation

authors： Baisch F,Beck L,Blomqvist G,Wolfram G,Drescher J,Rome JL,Drummer C

更新日期：2000-12-01 00:00:00

abstract：:Ten men with Klinefelter's syndrome were studied to assess the effect of testosterone replacement on plasma lipids and apolipoproteins. Measurements taken before the insertion of a testosterone ester implant were compared with those obtained 1 week and 4 weeks later. Mean plasma testosterone, androstenedione, total ch...

journal_title：European journal of clinical investigation

authors： Jones DB,Higgins B,Billet JS,Price WH,Edwards CR,Beastall GH,Shepherd J,Sweeting VM,Horn DB,Wenham PR

更新日期：1989-10-01 00:00:00

abstract：:Many diseases with a major public health impact are the result of complex interactions between environmental factors and multiple genes. In the past decade, methods for genome analysis, in particular quantitative trait locus (QTL) analysis in animal models, were developed to identify and localize the genes responsible...

journal_title：European journal of clinical investigation

authors： Hillebrandt S,Matern S,Lammert F

更新日期：2003-02-01 00:00:00

abstract：:A continuous intravenous infusion of L-leucine (300 mumols min-1) was given to 12 healthy females over a 2 1/2 h period. Arterial plasma concentrations of amino acids and the keto acids of the branched-chain amino acids (BCAA) were measured. In six subjects muscle biopsies were taken before and at the end of the infus...

journal_title：European journal of clinical investigation

authors： Alvestrand A,Hagenfeldt L,Merli M,Oureshi A,Eriksson LS

更新日期：1990-06-01 00:00:00

abstract：:Microparticles are small membrane vesicles that are released from cells upon activation or during apoptosis. Cellular microparticles in body fluids constitute a heterogeneous population, differing in cellular origin, numbers, size, antigenic composition and functional properties. Microparticles support coagulation by ...

journal_title：European journal of clinical investigation

authors： Diamant M,Tushuizen ME,Sturk A,Nieuwland R

更新日期：2004-06-01 00:00:00

abstract：BACKGROUND:Bone marrow (BM) histology/immunohistochemistry, KIT D816V mutation analysis and serum tryptase measurements are mandatory tools for diagnosis of systemic mastocytosis (SM). MATERIALS AND METHODS:Within the 'German Registry of Disorders on Eosinophils and Mast Cells', we identified 65 patients with SM who h...

journal_title：European journal of clinical investigation

authors： Jawhar M,Schwaab J,Horny HP,Sotlar K,Naumann N,Fabarius A,Valent P,Cross NC,Hofmann WK,Metzgeroth G,Reiter A

更新日期：2016-05-01 00:00:00

abstract：:Exogenous intravenous infusions of control saline, somatostatin, motilin and somatostatin and motilin together were compared in normal volunteers for their effects on the rise of blood glucose following 50 g oral glucose and for their effects on gastric emptying and plasma hormone concentrations. All regulatory peptid...

journal_title：European journal of clinical investigation

authors： Long RG,Christofides ND,Fitzpatrick ML,O'Shaughnessy DJ,Bloom SR

更新日期：1982-08-01 00:00:00

abstract：:Pulmonary plasma kinetics of endogenous noradrenaline (NA) and tritium labelled L-noradrenaline (3H-NA) was studied in fifteen subjects during pulmonary arterial catheterization. Plasma NA concentration in femoral artery ranged from 0.5 to 8.2 nmol l-1, mean 2.3 nmol l-1, which was not significantly different from tha...

journal_title：European journal of clinical investigation

authors： Henriksen JH,Christensen NJ,Ring-Larsen H

更新日期：1986-10-01 00:00:00

abstract：BACKGROUND:Soluble ST2 (sST2), a member of the IL-1 receptor family, has been proposed as a novel biomarker with predictive value for heart failure and mortality in patients suffering from cardiovascular diseases. The influence of clinical characteristics on variability of sST2 levels is relatively unexplored. Here, we...

journal_title：European journal of clinical investigation

authors： Willems S,Sels JW,Flier S,Versteeg D,Buhre WF,de Kleijn DP,Hoefer IE,Pasterkamp G

更新日期：2013-02-01 00:00:00

abstract：:Efficient fragmentation is the most important prerequisite for successful treatment of gallstones by extracorporeally induced shock waves. No data are available on the amount of energy necessary for stone disintegration and on the threshold energy below which no further fragmentation occurs. We therefore performed an ...

journal_title：European journal of clinical investigation

authors： Neubrand M,Greinwald I,Lobentanzer H,Paumgartner G,Hermeking H,Sauerbruch T

更新日期：1997-03-01 00:00:00

abstract：:Portal-systemic spill-over of unconjugated ursodeoxycholic acid (UDCA) was assessed in ten healthy subjects, six patients with mild chronic liver disease and eight patients with cirrhosis. Following oral administration of UDCA (1.5 mg/kg body weight), serum concentrations of unconjugated UDCA were measured during 2 h ...

journal_title：European journal of clinical investigation

authors： Miescher G,Paumgartner G,Preisig R

更新日期：1983-12-01 00:00:00

abstract：:N-3 fatty acids were supplied to a 36-year-old female patient suffering from ulcerative colitis and severe steroid side-effects, in a sequence of parenteral and enteral administration. During a moderately active period of disease, 200 ml d-1 fish oil-derived lipid emulsion (eicosapentaenoic acid [EPA], 4.2 g; docosahe...

journal_title：European journal of clinical investigation

authors： Grimminger F,Führer D,Papavassilis C,Schlotzer E,Mayer K,Heuer KU,Kiss L,Walmrath D,Piberhofer S,Lübbecke F

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:The Treating to New Targets (TNT) study has recently provided evidence that reduction in LDL-C levels below 2·6 mmol L⁻¹ lowers the risk of cerebrovascular events by an additional 20% to 25%, thereby confirming the value of statin therapy in preventing transient ischaemic attacks and stroke. Despite the prot...

journal_title：European journal of clinical investigation

authors： van den Bogaard B,van den Born BJ,Fayyad R,Waters DD,DeMicco DA,LaRosa JC,Kastelein JJ,Holme I,Treating to New Targets investigators.

更新日期：2011-02-01 00:00:00

abstract：:Sporadic hypophosphataemic osteomalacia (adult-onset type) was demonstrated in a 40-year-old man on the basis of severe osteomalacia, hypophosphataemia, hyperphosphaturia and glycinuria. Plasma immunoreactive parathyroid hormone (iPTH) concentration was 9.3 ng prot./ml (normal range: 4-8 ng prot./ml). Plasma 25-hydrox...

journal_title：European journal of clinical investigation

authors： Ulmann A,Bouchard P,Garabédian M,Bourdeau A,Witmer-Cournot G,Lacour B,Balsan S,Funck-Brentano JL

更新日期：1980-10-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the clinical applicability of transthoracic ultrasound (TUS) in the diagnosis and follow-up of community acquired pneumonia (CAP). METHODS:We designed a pilot study in 15 patients and subsequently investigated 342 patients (206 men and 136 women) consecutively admitted ...

journal_title：European journal of clinical investigation

authors： Sperandeo M,Carnevale V,Muscarella S,Sperandeo G,Varriale A,Filabozzi P,Piattelli ML,D'Alessandro V,Copetti M,Pellegrini F,Dimitri L,Vendemiale G

更新日期：2011-01-01 00:00:00

abstract：:We present a sensitive time-resolved fluorometric immunofunctional assay (TR-FIA) for direct quantitation of functional growth hormone-binding protein (GHBP), using an immunoassay kit for growth hormone (GH-DELFIA). In addition to the immobilized GH antibody, one monoclonal antibody against GHBP was used. This anti-GH...

journal_title：European journal of clinical investigation

authors： Fisker S,Frystyk J,Skriver L,Vestbo E,Ho KK,Orskov H

更新日期：1996-09-01 00:00:00

abstract：:Tightly co-ordinated control of both insulin action and secretion is required in order to maintain glucose homeostasis. Gene knockout experiments have helped to define key signalling molecules that affect insulin action, including insulin and insulin-like growth factor-1 (IGF-1) receptors, insulin receptor substrate (...

journal_title：European journal of clinical investigation

authors： Rhodes CJ,White MF

更新日期：2002-06-01 00:00:00

abstract：:Metabolic alterations related to resting energy expenditure (REE) and fat metabolism have been noted during sepsis, and often depend on the causative agent and the stage and severity of the illness. We studied the effect of IL-1, the protein mediator of the 'acute phase' response during infection, on REE, respiratory ...

journal_title：European journal of clinical investigation

authors： Tocco-Bradley R,Georgieff M,Jones CT,Moldawer LL,Dinarello CA,Blackburn GL,Bistrian BR

更新日期：1987-12-01 00:00:00

abstract：:The retardation of gastric emptying induced by infusion of triglyceride into the small intestine is associated with suppression of antral pressure waves and stimulation of basal pyloric tone in combination with phasic pressure waves localized to the pylorus. The role of nitric oxide (NO) mechanisms in the control of p...

journal_title：European journal of clinical investigation

authors： Sun WM,Doran S,Lingenfelser T,Hebbard GS,Morley JE,Dent J,Horowitz M

更新日期：1996-08-01 00:00:00

abstract：:Washed cells, from ascitic fluid, which contained predominantly polymorphonuclear leucocytes from casein treated donor mice, induced accelerated amyloid formation in untreated syngeneic recipient animals. A similar transfer model, with lymph node cell suspension, was ineffective. Amyloidogenesis was completely blocked...

journal_title：European journal of clinical investigation

authors： Kedar I,Ravid M

更新日期：1980-02-01 00:00:00

abstract：OBJECTIVE:To investigate alterations in endothelial nitric oxide synthase and inducible nitric oxide synthase mRNA expressions and nitric oxide release in the myocardium during ischaemia/reperfusion and determine whether these changes are ischaemic and/or reperfusion dependent. MATERIALS AND METHODS:Isolated rat heart...

journal_title：European journal of clinical investigation

authors： Pevni D,Frolkis I,Shapira I,Schwartz D,Schwartz IF,Chernichovski T,Lev-Ran O,Sharony R,Uretzky G

更新日期：2005-09-01 00:00:00

abstract：BACKGROUND:CD33 (Siglec-3) is becoming increasingly important as a target of antibody-mediated therapy in acute myeloid leukaemia (AML). In normal myelopoiesis, expression of CD33 is restricted to advanced stages of differentiation, whereas primitive stem cells do not express CD33. In the present study, we asked whethe...

journal_title：European journal of clinical investigation

authors： Hauswirth AW,Florian S,Printz D,Sotlar K,Krauth MT,Fritsch G,Schernthaner GH,Wacheck V,Selzer E,Sperr WR,Valent P

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:Age is one the factors associated with poor prognosis in acute coronary syndromes (ACS) and elderly patients are a high-risk collective with few parameters for mid-term cardiovascular stratification. We aimed to assess the predictive value of ankle-brachial index (ABI) in patients (> 75 years) for 1-year mor...

journal_title：European journal of clinical investigation

authors： Cordero A,Morillas P,Bertomeu-González V,Quiles J,Soria F,Guindo J,Mazón P,Anguita M,Rodríguez-Padial L,González-Juanatey JR,Bertomeu-Martínez V,en nombre de los investigadores del estudio PAMISCA.

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Complement fragment C5a and neutrophils have been implicated in the pathogenesis of renal disease and C5a has also been shown to delay apoptosis of human neutrophils via a transcription-independent pathway. However, transcription-dependent pathways have not been well described. The present study examined whe...

journal_title：European journal of clinical investigation

authors： Perianayagam MC,Madias NE,Pereira BJ,Jaber BL

更新日期：2006-05-01 00:00:00

abstract：:In this study the muscarinic receptor antagonist atropine and the cholecystokinin (CCK)-A receptor antagonist loxiglumide were used to investigate the relative importance of cholinergic and CCK-mediated regulation of intestinal phase antro-pyloro-duodenal motility. Plasma levels of gastrointestinal hormones [pancreati...

journal_title：European journal of clinical investigation

authors： Katschinski M,Schirra J,Begliner C,Langbein S,Wank U,D'Amato M,Arnold R

更新日期：1996-07-01 00:00:00

abstract：:The most well characterized function of pulmonary surfactant is its ability to reduce surface tension at the alveolar air-liquid interface, thereby preventing lung collapse. However, several lines of evidence suggest that surfactant may also have 'non-surfactant' functions: specific components of surfactant (proteins ...

journal_title：European journal of clinical investigation

authors： Pison U,Max M,Neuendank A,Weissbach S,Pietschmann S

更新日期：1994-09-01 00:00:00

abstract：:Transfers or exchanges of cholesterol esters and triglycerides between lipoproteins are mediated by a specialized protein referred to as cholesteryl ester transfer protein (CETP), whereas those of phospholipids (PLs) are facilitated by both CETP and a specific phospholipid transfer protein (PLTP). In the present study...

journal_title：European journal of clinical investigation

authors： Elchebly M,Pulcini T,Porokhov B,Berthezene F,Ponsin G

更新日期：1996-03-01 00:00:00

abstract：:Adequate pregnancy care of women with systemic lupus erythematosus (SLE) rests on three pillars: a coordinated medical-obstetrical care, an agreed and well-defined management protocol and a good neonatal unit. Pregnancy should be planned following a preconceptional visit for counselling. Women with severe active disea...

journal_title：European journal of clinical investigation

authors： Ruiz-Irastorza G,Khamashta MA

更新日期：2011-06-01 00:00:00

abstract：:Immunoreactive parathyroid hormone (PTH) levels and nephrogenous cyclic adenosine monophosphate (cAMP) have been reported to be useful parameters in the diagnosis of hyperparathyroidism. Measurements in hyperparathyroid patients usually give values above the normal range when PTH is measured with a carboxyterminal rad...

journal_title：European journal of clinical investigation

authors： Bill G,Jacquet AF,Burckhardt P

更新日期：1984-06-01 00:00:00

abstract：:Plasma glucose concentration is the best predictor for the development of non-insulin-dependent diabetes mellitus (NIDDM). However, obesity is also a recognized risk factor for development of the disease, and is easier to track over time. Thus obesity could be of considerable clinical importance as a predictor of diab...

journal_title：European journal of clinical investigation

authors： Ferrannini E,Camastra S

更新日期：1998-09-01 00:00:00