Abstract：
PURPOSE:The aim of this study was to investigate the clinical applicability of transthoracic ultrasound (TUS) in the diagnosis and follow-up of community acquired pneumonia (CAP). METHODS:We designed a pilot study in 15 patients and subsequently investigated 342 patients (206 men and 136 women) consecutively admitted to our Department from September 2005 to November 2009 because of radiographically diagnosed CAP. All patients underwent standard chest radiography, and consequently TUS. Follow-up TUS were performed at 4th and 8-10th day, in most patients. RESULTS:Concerning the reproducibility of TUS method, no reader's bias was present (P=0·18), overall variability and between-subject variability (inter-reader agreement) did not show any difference between readers (P = 0·62 and P = 0·32 respectively), and estimated within-subject variabilities (intra-reader agreement) suggested a very high repeatability of the method (P ∼ 1). Of 342 patients with Rx diagnosis of CAP, in 314 patients (92% of cases) a pulmonary consolidation was also detected using TUS, whose ultrasonographic patterns were studied. Pleural effusion was detected in 120/342 (35%) patients using ultrasound and in 111/342 (32%) patients using chest radiography. Overall dimensional changes of the lung consolidated areas assessed with TUS method showed highly significant results. (1st day mean ± SD: 66·34 ± 19·25; 4th day: 39·92 ± 14·61; 8-10th day: 7·41 ± 1·50; P < 0·0001). CONCLUSIONS:TUS is easily reproducible and we proved it to be a useful complementary diagnostic tool for the diagnosis and the follow-up of CAP.
journal_name
Eur J Clin Investjournal_title
European journal of clinical investigationauthors
Sperandeo M,Carnevale V,Muscarella S,Sperandeo G,Varriale A,Filabozzi P,Piattelli ML,D'Alessandro V,Copetti M,Pellegrini F,Dimitri L,Vendemiale Gdoi
10.1111/j.1365-2362.2010.02367.xsubject
Has Abstractpub_date
2011-01-01 00:00:00pages
1-7issue
1eissn
0014-2972issn
1365-2362pii
ECI2367journal_volume
41pub_type
杂志文章abstract：:We measured the renal haemodynamic and proteinuric response to a meat meal (MM) in ten persistently proteinuric insulin-dependent diabetic patients in a randomized cross-over study of 3 weeks on low protein diet (LPD) or normal protein intake (NPD). On LPD, protein intake (0.64 +/- 0.05 vs 1.15 +/- 0.09 g kg-1 body we...
journal_title：European journal of clinical investigation
pub_type： 临床试验,杂志文章,随机对照试验
doi：10.1111/j.1365-2362.1991.tb01807.x
更新日期：1991-04-01 00:00:00
abstract：BACKGROUND:Predictors of gingival enlargement in patients treated with anti-epileptics have not been previously assessed. This study was conducted to determine, with the aid of two indices that score vertical and horizontal overgrowth, the prevalence and risk factors for gingival enlargement in patients treated with ph...
journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1046/j.1365-2362.2001.00869.x
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abstract：:Investigations have been carried out to explain the heterogeneity of response to catecholamines of human fat cells from various deposits. Adipocytes from two subcutaneous sites (abdominal and femoral) were studied concomitantly in women while omental fat cells were taken from another group of patients undergoing abdom...
journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1111/j.1365-2362.1987.tb02395.x
更新日期：1987-04-01 00:00:00
abstract：BACKGROUND:The role of the pattern, quantity and site of insulin secretion in the tolerance to a glucose challenge is not fully evaluated in humans because it is difficult to obtain appropriate clinical models. DESIGN:To address this issue, we studied subjects with reduced pancreatic mass (hemipancreatectomized, HEMI)...
journal_title：European journal of clinical investigation
pub_type： 临床试验,杂志文章
doi：10.1046/j.1365-2362.2000.00648.x
更新日期：2000-05-01 00:00:00
abstract：:The effects of dazoxiben on finger-blood flow in response to cold challenge were studied in normal subjects and patients with Raynaud's phenomenon. In normal subjects concentrations of TXB2 and 6-oxo-PGF1 alpha were measured in blood taken from dorsal hand veins following cold challenge. In a parallel multicentre stud...
journal_title：European journal of clinical investigation
pub_type： 临床试验,杂志文章,随机对照试验
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更新日期：1985-02-01 00:00:00
abstract：BACKGROUND:Low blood levels of antioxidants are associated with an increased risk of developing coronary artery disease. Lipophilic antioxidants are transported in lipoproteins, and hypolipidaemic therapy may therefore alter their blood concentrations. METHODS:The present randomized, placebo-controlled cross-over stud...
journal_title：European journal of clinical investigation
pub_type： 临床试验,杂志文章,随机对照试验
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1111/j.1365-2362.1988.tb02404.x
更新日期：1988-04-01 00:00:00
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1111/j.1365-2362.1995.tb01983.x
更新日期：1995-09-01 00:00:00
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journal_title：European journal of clinical investigation
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journal_title：European journal of clinical investigation
pub_type： 杂志文章,评审
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更新日期：2017-06-01 00:00:00
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1046/j.1365-2362.1997.1690724.x
更新日期：1997-08-01 00:00:00
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1111/j.1365-2362.1977.tb01587.x
更新日期：1977-04-01 00:00:00
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1046/j.1365-2362.1998.00332.x
更新日期：1998-09-01 00:00:00
abstract：BACKGROUND:The intestinal handling of dextran, an alpha-1,6-linked glucose polymer, is poor compared with starch, and some ingested dextran might therefore reach the lower small intestine. As luminal sugar up-regulates SGLT1 (sodium-dependent glucose transporter) locally, we report the effects of a dextran-enriched die...
journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1046/j.1365-2362.1998.00352.x
更新日期：1998-08-01 00:00:00
abstract：BACKGROUND:Inflammation and immune activation appear to be important in the pathogenesis of coronary heart disease (CHD). Cytokine interferon-gamma, which is released during cell-mediated immune responses, induces indoleamine (2,3)-dioxygenase (IDO), an enzyme degrading tryptophan to kynurenine. Therefore, immune stimu...
journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1046/j.1365-2362.2003.01186.x
更新日期：2003-07-01 00:00:00
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journal_title：European journal of clinical investigation
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journal_title：European journal of clinical investigation
pub_type： 杂志文章
doi：10.1111/j.1365-2362.1989.tb00206.x
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journal_title：European journal of clinical investigation
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journal_title：European journal of clinical investigation
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doi：10.1046/j.1365-2362.2001.00770.x
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journal_title：European journal of clinical investigation
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doi：10.1111/j.1365-2362.1986.tb02169.x
更新日期：1986-12-01 00:00:00
abstract：INTRODUCTION:Diabetes mellitus is a progressive disease with cardiovascular complications. This study evaluated the effects of liraglutide, a glucagon-like peptide-1 analogue and the dipeptidyl peptidase 4 inhibitors sitagliptin and linagliptin on cardiac function in type 2 diabetes patients with renal impairment. MAT...
journal_title：European journal of clinical investigation
pub_type： 杂志文章,随机对照试验
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更新日期：2018-10-01 00:00:00
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journal_title：European journal of clinical investigation
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journal_title：European journal of clinical investigation
pub_type： 杂志文章,评审
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journal_title：European journal of clinical investigation
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doi：10.1111/j.1365-2362.1988.tb02416.x
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abstract：:The esterolytic activity of mixed and parotid saliva in cystic fibrosis (CF) patients and normal subjects was determined using BAEE (alpha-Benzoyl-1-arginine-ethylester) as the substrate. Using soybean-trypsin-inhibitor the trypsin-like activity (TLA) was measured and plotted as a function of parotid flow rate. In add...
journal_title：European journal of clinical investigation
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doi：10.1111/j.1365-2362.1975.tb00441.x
更新日期：1975-04-01 00:00:00
abstract：BACKGROUND:The tetrapeptide acetyl-Ser-Asp-Lys-Pro (AcSDKP), a physiological inhibitor of the proliferation of haematopoietic stem cells, is degraded by the angiotensin-I-converting enzyme (ACE). Whereas synthetic AcSDKP (Goralatide) protects normal mice from the haematological toxicity of chemotherapy, it has a lower ...
journal_title：European journal of clinical investigation
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doi：10.1046/j.1365-2362.1998.00356.x
更新日期：1998-10-01 00:00:00
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journal_title：European journal of clinical investigation
pub_type： 杂志文章,评审
doi：10.1111/j.1365-2362.2004.01355.x
更新日期：2004-06-01 00:00:00
abstract：BACKGROUND:To reveal detailed histopathological changes, virus distributions, immunologic properties and multi-omic features caused by SARS-CoV-2 in the explanted lungs from the world's first successful lung transplantation of a COVID-19 patient. MATERIALS AND METHODS:A total of 36 samples were collected from the lung...
journal_title：European journal of clinical investigation
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
