Pituitary-testicular function in acromegalic and hypophysectomized patients.

abstract：BACKGROUND:There is an ongoing debate on a potential protective role of habitual physical activity and passive heat therapy on the risk of COVID-19, a respiratory infectious disease that can manifest as severe pneumonia. To explore these putative roles, we evaluated the independent and joint associations of cardiorespi...

journal_title：European journal of clinical investigation

authors： Kunutsor SK,Laukkanen JA

更新日期：2021-01-10 00:00:00

abstract：:Sporadic hypophosphataemic osteomalacia (adult-onset type) was demonstrated in a 40-year-old man on the basis of severe osteomalacia, hypophosphataemia, hyperphosphaturia and glycinuria. Plasma immunoreactive parathyroid hormone (iPTH) concentration was 9.3 ng prot./ml (normal range: 4-8 ng prot./ml). Plasma 25-hydrox...

journal_title：European journal of clinical investigation

authors： Ulmann A,Bouchard P,Garabédian M,Bourdeau A,Witmer-Cournot G,Lacour B,Balsan S,Funck-Brentano JL

更新日期：1980-10-01 00:00:00

abstract：:Two methods of measurement of fractional calcium absorption have been compared in the same individuals. There is a significant correlation between fractional 47Ca absorption as measured with a blood counting method and with an external counting method after intravenous and oral administration of 47Ca (P less than 0.00...

journal_title：European journal of clinical investigation

authors： Juttmann JR,Ruis AM,Hagenouw-Taal JC,Lockefeer JH,Birkenhäger JC

更新日期：1978-06-01 00:00:00

abstract：:Oral lichen planus (OLP) is a common oral disorder that manifests a mucosal reaction to a variety of aetiological factors, including liver disorder. This study investigated the relationship between OLP and hepatitis C virus (HCV) infection by studying the prevalence of hepatitis B and C virus infection or liver diseas...

journal_title：European journal of clinical investigation

authors： Nagao Y,Sata M,Tanikawa K,Itoh K,Kameyama T

更新日期：1995-12-01 00:00:00

abstract：BACKGROUND:Hyperlipidemia is a common feature of the nephrotic syndrome (NS). From retrospective studies, it has been suggested that aggressive lipid-lowering with low-density lipoprotein apheresis (LDL-A) may not only improve dyslipidemia but also decrease urinary albumin excretion and increase serum levels of albumin...

journal_title：European journal of clinical investigation

authors： Stenvinkel P,Alvestrand A,Angelin B,Eriksson M

更新日期：2000-10-01 00:00:00

abstract：BACKGROUND:Parental history of type 2 diabetes (T2D) is associated with cardiometabolic risk. We aimed to investigate the associations of parental history of T2D with cardiometabolic biomarkers and to subsequently investigate to what extent these putative associations were explained by modifiable factors. MATERIALS AN...

journal_title：European journal of clinical investigation

authors： Abbasi A,Corpeleijn E,van der Schouw YT,Stolk RP,Spijkerman A,van der A DL,Navis G,Bakker SJ,Beulens JW

更新日期：2012-09-01 00:00:00

abstract：BACKGROUND:The intestinal mucosa of patients with inflammatory bowel diseases (IBD) characteristically shows a high degree of inflammation when compared to healthy subjects. This appears to be attributable to an imbalance in local reactivity of inflammatory cells. In the present study, we tested the hypothesis that imm...

journal_title：European journal of clinical investigation

authors： Kovarik JJ,Tillinger W,Hofer J,Hölzl MA,Heinzl H,Saemann MD,Zlabinger GJ

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Thiopurines (TP) are widely used in the management of inflammatory bowel diseases. Side effects and inefficacy are a major concern as they lead to withdrawal of the drug. MATERIALS AND METHODS:Tools investigating TP metabolism are useful to avoid inadequate cessation of TP therapy. RESULTS:TP metabolism is...

journal_title：European journal of clinical investigation

authors： Dewit O,Starkel P,Roblin X

更新日期：2010-11-01 00:00:00

abstract：BACKGROUND:Cold ischaemic (CI) injury is associated with reduced renal graft function and survival. However, there is little evidence on the benefits of reducing CI injury within a 24 h period in donation after cardiac death (DCD) kidney transplantation. METHODS:Porcine kidneys subjected to 10-min warm ischaemia were ...

journal_title：European journal of clinical investigation

authors： Hosgood SA,Bagul A,Nicholson ML

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND:Burnout represents a syndrome that is related to demanding job characteristics combined with the absence of resources or motivational job characteristics. The aim of this position study was to present strategies that individuals use to minimize burnout and its unfavourable effects. MATERIALS AND METHODS:The...

journal_title：European journal of clinical investigation

authors： Demerouti E

更新日期：2015-10-01 00:00:00

abstract：BACKGROUND:We recently reported high high-density lipoprotein (HDL) cholesterol as a predictor of recurrent risk in a subgroup of postinfarction patients defined by hypercholesterolemia and high C-reactive protein (CRP) levels. We investigated whether a similar high-risk subgroup might exist for incident cardiovascular...

journal_title：European journal of clinical investigation

authors： Corsetti JP,Gansevoort RT,Sparks CE,Dullaart RP

更新日期：2010-06-01 00:00:00

abstract：BACKGROUND:The acute-phase response and anaemia of chronic disease are characterized by hypoferraemia associated with an increased ferritin synthesis, which might be mediated by the activated cytokine cascade. METHODS:We examined the prolonged effects of isolated limb perfusion (ILP) with recombinant human tumour necr...

journal_title：European journal of clinical investigation

authors： Feelders RA,Vreugdenhil G,Eggermont AM,Kuiper-Kramer PA,van Eijk HG,Swaak AJ

更新日期：1998-07-01 00:00:00

abstract：BACKGROUND:In obese subjects, chronic low-grade inflammation contributes to an increased risk of metabolic abnormalities, which are reversed by weight loss. Sustained weight loss, however, is difficult to achieve and more insight into dietary approaches on anti-inflammatory responses in obese subjects is needed. In thi...

journal_title：European journal of clinical investigation

authors： Jellema A,Plat J,Mensink RP

更新日期：2004-11-01 00:00:00

abstract：BACKGROUND:Cardiac resynchronization therapy (CRT) is an established therapy for advanced congestive heart failure, improving both survival and hospitalization. The mechanism beneath these improvements still needs to be defined as about one-third of the patients do not benefit from resynchronization. Restoration of sym...

journal_title：European journal of clinical investigation

authors： Martignani C,Diemberger I,Nanni C,Biffi M,Ziacchi M,Boschi S,Corzani A,Fanti S,Sambuceti G,Boriani G

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Irisin, a novel myokine, has been shown to increase following vigorous exercise, with studies suggesting that it mediates some of the beneficial effects of exercise. Irisin might play a role in 'browning' of white adipocytes, thus increasing energy expenditure. The role of irisin in exercise and energy expen...

journal_title：European journal of clinical investigation

authors： Al-Daghri NM,Alokail MS,Rahman S,Amer OE,Al-Attas OS,Alfawaz H,Tripathi G,Sabico S,Chrousos GP,McTernan PG,Piya MK

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND:Prevalence of fatty liver (FL) and nonalcoholic fatty liver disease (NAFLD) depends mainly on obesity, diabetes and genetic factors. FL and NAFLD prevalence was evaluated in Portuguese adult population and correlated with several risk factors and related mortality data, within the same period. MATERIALS AND...

journal_title：European journal of clinical investigation

authors： Leitão J,Carvalhana S,Cochicho J,Silva AP,Velasco F,Medeiros I,Alves AC,Bourbon M,Oliveiros B,Rodrigues V,Sousa R,Sampaio F,Carvalho A,Cortez-Pinto H

更新日期：2020-06-01 00:00:00

abstract：:Triosephosphate isomerase deficiencies in erythrocytes and leucocytes were discovered in three unrelated families by a heterozygote screening of 3000 blood samples. In addition, a family found by Schroter et al. [not published] was studied. In these four families, only heterozygote carriers were found. In the family d...

journal_title：European journal of clinical investigation

authors： Eber SW,Dünnwald M,Belohradsky BH,Bidlingmaier F,Schievelbein H,Weinmann HM,Krietsch KG

更新日期：1979-06-01 00:00:00

abstract：:During chronic high-altitude (HA) exposure, basal and exercise-induced noradrenaline (NA) increases do not parallel blood pressure (BP) changes observed; unlike beta-adrenergic receptors, to our knowledge no data are available on alpha-receptors. We studied platelet alpha 2- and leucocyte beta-receptors and basal cate...

journal_title：European journal of clinical investigation

authors： Zaccaria M,Borea PA,Opocher G,Ponchia A,Varani K,Fraccarollo D,Scandellari C

更新日期：1997-04-01 00:00:00

abstract：BACKGROUND:Cardiovascular patients suffer from reduced blood flow leading to ischaemia and impaired tissue metabolism. Unfortunately, an increasing group of elderly patients cannot be treated with current revascularization methods. Thus, new treatment strategies are urgently needed. Hypoxia-inducible factors (HIFs) upr...

journal_title：European journal of clinical investigation

authors： Niemi H,Honkonen K,Korpisalo P,Huusko J,Kansanen E,Merentie M,Rissanen TT,André H,Pereira T,Poellinger L,Alitalo K,Ylä-Herttuala S

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:There is growing evidence that the predictive value of HDL cholesterol levels for cardiovascular risk stratification is limited in patients with coronary artery disease (CAD). HDL function seems to be a more sensitive surrogate of cardiovascular risk estimation than simple serum levels. Therefore, we aimed t...

journal_title：European journal of clinical investigation

authors： Distelmaier K,Wiesbauer F,Blessberger H,Oravec S,Schrutka L,Binder C,Dostal E,Schillinger M,Wojta J,Lang IM,Maurer G,Huber K,Goliasch G

更新日期：2015-07-01 00:00:00

abstract：:The saphenous vein is the most commonly used graft for revascularization procedures in patients with coronary artery disease and critical limb ischaemia. However, the patency rate of this vessel is poor, with a high proportion of patients requiring further surgery. Early graft occlusion is caused by vasoconstriction o...

journal_title：European journal of clinical investigation

authors： Dashwood MR

更新日期：2009-06-01 00:00:00

abstract：BACKGROUND:Many haemodialysis patients treated with recombinant human erythropoietin (r-HuEPO) receive intravenous iron supplementation on a regular basis. It has been shown previously that this may result in a transient "oversaturation" of transferrin. METHODS:Ten stable haemodialysis patients on r-HuEPO treatment re...

journal_title：European journal of clinical investigation

authors： Kooistra MP,Kersting S,Gosriwatana I,Lu S,Nijhoff-Schutte J,Hider RC,Marx JJ

更新日期：2002-03-01 00:00:00

abstract：:Two cases of congenital defect in iodide trapping mechanism are related. The absence of thyroid and gastric concentration of 99mTcO4 led to the diagnosis. The study of saliva and gastric:serum concentration ratios confirmed the complete defect. The kinetics of radioiodine studied by external detection showed an early ...

journal_title：European journal of clinical investigation

authors： Leger FA,Doumith R,Courpotin C,Helal OB,Davous N,Aurengo A,Savoie JC

更新日期：1987-06-01 00:00:00

abstract：BACKGROUND:Both inflammation and oxidative stress may contribute to pathogenesis of metabolic syndrome (MetS). The C242T polymorphism (rs4673) in the CYBA gene, as the main components of NAD (P) H oxidase, causes inter-individual variability in the enzyme activity. We aimed to investigate the association between this p...

journal_title：European journal of clinical investigation

authors： Pourgholi L,Pourgholi F,Ziaee S,Goodarzynejad H,Hosseindokht M,Boroumand M,Mandegary A

更新日期：2020-09-01 00:00:00

abstract：:The effects of treating the anaemia of end-stage renal failure with erythropoietin were studied in nine dialysis patients. The increase in haemoglobin concentration (by 59% from 7.0 +/- 1.2 to 11.1 +/- 1.1 g dl-1) was associated with increases in exercise duration (by 41%) and maximum oxygen consumption (by 34%). Trea...

journal_title：European journal of clinical investigation

authors： Lewis NP,Macdougall IC,Willis N,Coles GA,Williams JD,Henderson AH

更新日期：1993-07-01 00:00:00

abstract：:Duchenne muscular dystrophy (DMD) is an X-linked muscle disorder characterized by progressive, irreversible loss of cardiac and skeletal muscular function. Muscular enlargement in DMD is attributed to oedema, due to the increased cytoplasmic Na+ concentration. The aim of this review was to present the current experien...

journal_title：European journal of clinical investigation

authors： Mavrogeni S,Papavasiliou A,Giannakopoulou K,Markousis-Mavrogenis G,Pons MR,Karanasios E,Nikas I,Papadopoulos G,Kolovou G,Chrousos GP

更新日期：2017-12-01 00:00:00

abstract：:ATPase activities were determined in haemolysed and dialysed erythrocytes and in haemoglobin-free membranes of twenty patients with essential hypertension and twenty normotensive controls. Ouabain-sensitive ATPase (Na-K-ATPase) activity of haemolysate but not that of membranes was decreased in hypertensives whereas ou...

journal_title：European journal of clinical investigation

authors： Walter U,Müller S

更新日期：1985-08-01 00:00:00

abstract：BACKGROUND:Linear growth restriction is a unique feature of paediatric inflammatory bowel diseases (IBD), and reduced insulin-like growth factor (IGF-1) is a major determinant of short stature. We aimed to assess factors influencing somatic height in children suffering from IBD. MATERIALS AND METHODS:This was a retros...

journal_title：European journal of clinical investigation

authors： Chouliaras G,Mantzou A,Margoni D,Tsilifis N,Pervanidou P,Panayotou I,Kanaka-Gantenbein C,Chrousos GP,Roma-Giannikou E

更新日期：2018-08-01 00:00:00

abstract：:The impact of running and menstrual disturbances on regional and total body fat distribution and serum lipids was investigated in 205 women. Body composition was measured by dual-energy X-ray absorptiometry. The total fat mass in the elite runners was approximately half of the normally active's (7.3 [0.48] kg vs. 14.3...

journal_title：European journal of clinical investigation

authors： Hetland ML,Haarbo J,Christiansen C

更新日期：1995-08-01 00:00:00

abstract：:Microdialysis was used to selectively assess the effect of the paracrine renin-angiotensin system (RAS) on interstitial glucose and lactate concentration profiles in skeletal muscle of healthy volunteers (n = 8) during basal and insulin-stimulated conditions. Paracrine RAS was selectively inhibited by local retrodialy...

journal_title：European journal of clinical investigation

authors： Müller M,Fasching P,Schmid R,Burgdorff T,Waldhäusl W,Eichler HG

更新日期：1997-10-01 00:00:00