Abstract：
:Different families of functionalized polymers with potential as biomaterials, or for biomaterial modification, have been investigated. In particular, degradation studies have been performed on poly(amidoamines), a family of polymers obtained by polyaddition of amines to bisacrylamides, and endowed with heparin-complexing ability. Some new poly(amidoamines) with more resistance towards hydrolytic degradation than traditional ones have been discovered. Other ter-amino polymers deriving from the polyaddition of ter-amino functionalized bis-thiols to bis-acrylic esters, or other activated unsaturated compounds, have been studied. Their quaternarization products have been proven, in a parallel work, to act as powerful antimicrobial agents. By performing in situ the polyaddition reaction, semi-interpenetrated networks based on silicone rubber and the same polymers have been prepared. Finally, end-functionalized amphiphilic oligomers have been prepared by radical polymerization techniques, and their use for enzyme modification considered.
journal_name
Biomaterialsjournal_title
Biomaterialsauthors
Ferruti P,Ranucci E,Sartore L,Bignotti F,Marchisio MA,Bianciardi P,Veronese FMdoi
10.1016/0142-9612(94)90275-5subject
Has Abstractpub_date
1994-12-01 00:00:00pages
1235-41issue
15eissn
0142-9612issn
1878-5905pii
0142-9612(94)90275-5journal_volume
15pub_type
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