Acute cytomegalovirus infection in a child with Ménétrier's disease.

abstract：:A variety of noninvasive molecular approaches to colorectal cancer screening are emerging with potential to improve screening effectiveness and user-friendliness. These approaches are based on the sensitive assay of molecular markers in stool, blood, and urine samples. New methods, especially next generation stool-bas...

journal_title：Gastroenterology

authors： Ahlquist DA

更新日期：2010-06-01 00:00:00

abstract：:A new experimental model, the isolated perfused antrectomized pig stomach with intact vagal innervation, was shown to produce pepsinogen and gastric acid upon electrical stimulation of the vagus nerves and by intravascular administration of carbachol (from a basal value of 111 +/- 24 units of pepsin per minute and 0.0...

journal_title：Gastroenterology

authors： Skak-Nielsen T,Holst JJ,Nielsen OV

更新日期：1988-11-01 00:00:00

abstract：BACKGROUND:Increased intestinal macromolecular permeability could allow absorption of substances from the bowel into the systemic circulation and contribute to multiple organ system failure. METHODS:Mild, intermediate, and severe grades of pancreatitis were induced in rats using intravenous caerulein and intraductal g...

journal_title：Gastroenterology

authors： Ryan CM,Schmidt J,Lewandrowski K,Compton CC,Rattner DW,Warshaw AL,Tompkins RG

更新日期：1993-03-01 00:00:00

abstract：:The incidence of celiac disease is increasing, partly because of improved recognition of, and testing for, the disease. The rise in incidence is also due to a real increase of this immune-based disorder, independent of disease detection. The reasons for this true rise in recent decades are unknown but may be related t...

journal_title：Gastroenterology

authors： Lebwohl B,Rubio-Tapia A

更新日期：2021-01-01 00:00:00

abstract：BACKGROUND & AIMS:Prostaglandin-endoperoxide synthase (Ptgs)2 is an enzyme involved in prostaglandin production during the response to mucosal damage. Its expression is regulated, in part, by messenger RNA (mRNA)-binding proteins that control the stability of Ptgs2 mRNA. We used a precise system of colonic injury and r...

journal_title：Gastroenterology

authors： Manieri NA,Drylewicz MR,Miyoshi H,Stappenbeck TS

更新日期：2012-07-01 00:00:00

abstract：:A rapid immunohistochemical method using 5'-bromo-2'-deoxyuridine (BrdU), a thymidine analog, for labeling proliferating epithelial cells was modified and tested for accuracy against standard tritiated thymidine autoradiography (3H-TdR) in rat esophagus, stomach, duodenum, and colon. Either BrdU or 3H-thymidine or bot...

journal_title：Gastroenterology

authors： Lacy ER,Kuwayama H,Cowart KS,King JS,Deutz AH,Sistrunk S

更新日期：1991-01-01 00:00:00

abstract：BACKGROUND & AIMS:Most patients with esophageal adenocarcinoma (EAC) present with de novo tumors. Although this could be due to inadequate screening strategies, the precise reason for this observation is not clear. We compared survival of patients with prevalent EAC with and without synchronous Barrett esophagus (BE) w...

journal_title：Gastroenterology

authors： Sawas T,Killcoyne S,Iyer PG,Wang KK,Smyrk TC,Kisiel JB,Qin Y,Ahlquist DA,Rustgi AK,Costa RJ,Gerstung M,Fitzgerald RC,Katzka DA,OCCAMS Consortium.

更新日期：2018-12-01 00:00:00

abstract：:Gallbladder stasis has been implicated in gallstone formation. Gallbladder filling and emptying were quantitated by computer-assisted cholescintigraphy in 41 normal subjects versus 26 patients with gallstones. Gallbladder contraction was induced by low-dose (1.2 U/kg . h) cholecystokinin infusion. Gallstone patients e...

journal_title：Gastroenterology

authors： Pomeranz IS,Shaffer EA

更新日期：1985-03-01 00:00:00

abstract：BACKGROUND & AIMS:Hereditary hemochromatosis is a common disorder of iron homeostasis characterized by increased dietary iron absorption and progressive iron accumulation, mainly in the liver. Most patients are homozygous for the C282Y mutation in the HFE gene. However, not all individuals carrying the hemochromatosis-...

journal_title：Gastroenterology

authors： Bensaid M,Fruchon S,Mazères C,Bahram S,Roth MP,Coppin H

更新日期：2004-05-01 00:00:00

abstract：BACKGROUND & AIMS:Hepatopulmonary syndrome (HPS) affects 10%-30% of patients with cirrhosis and portal hypertension and significantly increases mortality. Studies in experimental models indicate that pulmonary angiogenesis contributes to the development of HPS, but pathogenesis in humans is poorly understood. We invest...

journal_title：Gastroenterology

authors： Roberts KE,Kawut SM,Krowka MJ,Brown RS Jr,Trotter JF,Shah V,Peter I,Tighiouart H,Mitra N,Handorf E,Knowles JA,Zacks S,Fallon MB,Pulmonary Vascular Complications of Liver Disease Study Group.

更新日期：2010-07-01 00:00:00

abstract：BACKGROUND & AIMS:A previous 4-week trial of telbivudine in patients with chronic hepatitis B indicated marked antiviral effects with good tolerability, leading to the present 1-year phase 2b trial. METHODS:This randomized, double-blind, multicenter trial evaluated the efficacy and safety of telbivudine 400 or 600 mg/...

journal_title：Gastroenterology

authors： Lai CL,Leung N,Teo EK,Tong M,Wong F,Hann HW,Han S,Poynard T,Myers M,Chao G,Lloyd D,Brown NA,Telbivudine Phase II Investigator Group.

更新日期：2005-08-01 00:00:00

abstract：BACKGROUND & AIMS:Few data are available on the potential role of T lymphocytes in experimental acute pancreatitis. The aim of this study was to characterize their role in the inflammatory cascade of acute pancreatitis. METHODS:To type this issue, acute pancreatitis was induced by repeated injections of cerulein in nu...

journal_title：Gastroenterology

authors： Demols A,Le Moine O,Desalle F,Quertinmont E,Van Laethem JL,Devière J

更新日期：2000-03-01 00:00:00

abstract：BACKGROUND & AIMS:Abdominal bloating is a frequent complaint in irritable bowel syndrome (IBS), but its underlying mechanism remains uncertain. Our aim was to determine whether the abdominal wall, specifically its adaptation to intra-abdominal volumes, plays a role. METHODS:In 12 patients complaining of abdominal bloa...

journal_title：Gastroenterology

authors： Tremolaterra F,Villoria A,Azpiroz F,Serra J,Aguadé S,Malagelada JR

更新日期：2006-04-01 00:00:00

abstract：:Circulating precursors of mucosal immunoglobulin A plasma cells and T-cell immunoblasts migrate selectively into mucosal sites from the blood, but the mechanisms controlling this selective trafficking have not been determined. One possibility is that the site-specific extravasation of circulating effector cell populat...

journal_title：Gastroenterology

authors： Schmitz M,Nunez D,Butcher EC

更新日期：1988-03-01 00:00:00

abstract：:Ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, is more hydrophilic and less hepatotoxic than chenodeoxycholic acid. Because "lagodeoxycholic acid," the 12 beta-hydroxy epimer of deoxycholic acid, is also more hydrophilic than deoxycholic acid, it was hypothesized that it should also be less ...

journal_title：Gastroenterology

authors： Schmassmann A,Angellotti MA,Clerici C,Hofmann AF,Ton-Nu HT,Schteingart CD,Marcus SN,Hagey LR,Rossi SS,Aigner A

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND & AIMS:Toll-like receptors (TLRs) represent a class of transmembrane pattern recognition receptors essential for microbial recognition and control of innate immune responses. Commensal bacteria play an important role in maintaining tolerance and active stability of the intestinal epithelial barrier by suppre...

journal_title：Gastroenterology

authors： Cario E,Gerken G,Podolsky DK

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND/AIMS:Liver fat-storing cells (FSCs) actively proliferate and secrete extracellular matrix during liver injury. Platelet-derived growth factor (PDGF) is a potent mitogen for cultured FSCs. In the present study, we investigated the regulation of PDGF gene expression and production in cultured human liver FSCs....

journal_title：Gastroenterology

authors： Marra F,Choudhury GG,Pinzani M,Abboud HE

更新日期：1994-10-01 00:00:00

abstract：:Exogenous administration of substances extracted from rodent salivary glands may increase the resistance of gastric mucosal barrier to the disruptive actions of ulcerogenic agents and/or reduce acid secretory output. In the present study the influence of desalivation in the rat on acid secretory function and mucosal i...

journal_title：Gastroenterology

authors： Skinner KA,Tepperman BL

更新日期：1981-08-01 00:00:00

abstract：BACKGROUND & AIMS:Alcoholic patients with and without chronic liver disease have a high incidence of infection with hepatitis C virus (HCV). Long-term ethanol consumption in mice has been associated with a strikingly reduced CD8(+) cytotoxic T-lymphocyte (CTL) response to HCV nonstructural proteins following DNA-based ...

journal_title：Gastroenterology

authors： Aloman C,Gehring S,Wintermeyer P,Kuzushita N,Wands JR

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND & AIMS:In the absence of pathognomonic markers for Crohn's disease (CD) and ulcerative colitis (UC), the diagnosis of inflammatory bowel disease depends on a compendium of clinical, radiographic, endoscopic, and histologic criteria that bears imperfect specificity to the individual disorders. In 10% of cases...

journal_title：Gastroenterology

authors： Joossens S,Reinisch W,Vermeire S,Sendid B,Poulain D,Peeters M,Geboes K,Bossuyt X,Vandewalle P,Oberhuber G,Vogelsang H,Rutgeerts P,Colombel JF

更新日期：2002-05-01 00:00:00

abstract：BACKGROUND/AIMS:Ursodeoxycholic acid (UDCA) and colchicine have beneficial effects in primary biliary cirrhosis (PBC). The efficacy of colchicine and UDCA in PBC was compared in a 2-year placebo-controlled study (n = 90). METHODS:Clinical events, laboratory test results, and liver histology were recorded at the beginn...

journal_title：Gastroenterology

authors： Vuoristo M,Färkkilä M,Karvonen AL,Leino R,Lehtola J,Mäkinen J,Mattila J,Friman C,Seppälä K,Tuominen J

更新日期：1995-05-01 00:00:00

abstract：:The case of a 21-yr-old man, who died in cachexia after 2 yr of intermittent abdominal pain, bouts of diarrhea, and anorexia, is reported. Laboratory tests performed shortly before death disclosed signs of malabsorption. Radiologic examination of the gastrointestinal tract showed a coarse mucosal relief in the upper j...

journal_title：Gastroenterology

authors： Jacobs E,Ardichvili D,Perissino A,Gottignies P,Hanssens JF

更新日期：1979-10-01 00:00:00

abstract：:A recent study reports that patients with previous acute pancreatitis commonly have an abnormal clearance of serum triglycerides after an oral fat load. This observation supports the hypothesis that patients with previous acute pancreatitis and normal fasting serum triglyceride levels may have a preexistent abnormalit...

journal_title：Gastroenterology

authors： Rollán A,Guzmán S,Pimentel F,Nervi F

更新日期：1990-06-01 00:00:00

abstract：:Uptake of inorganic sulfate into brush-border membrane vesicles isolated by a calcium precipitation method from rat small intestine was investigated using a rapid filtration technique and 35Sulfur acid as tracer. Sulfate uptake by membrane vesicles was osmotically sensitive, suggesting transport into an intravesicular...

journal_title：Gastroenterology

authors： Lücke H,Stange G,Murer H

更新日期：1981-01-01 00:00:00

abstract：BACKGROUND & AIMS:Biliary atresia (BA) is a rare disease in infants, with unknown mechanisms of pathogenesis. It is characterized by hepatobiliary inflammatory, progressive destruction of the biliary system leading to liver fibrosis, and deterioration of liver function. Interleukin (IL) 17A promotes inflammatory and au...

journal_title：Gastroenterology

authors： Klemann C,Schröder A,Dreier A,Möhn N,Dippel S,Winterberg T,Wilde A,Yu Y,Thorenz A,Gueler F,Jörns A,Tolosa E,Leonhardt J,Haas JD,Prinz I,Vieten G,Petersen C,Kuebler JF

更新日期：2016-01-01 00:00:00

abstract：BACKGROUND & AIMS:Studies on the early steps in the life cycle of hepatitis B virus have been hampered by the lack of readily available target cells. In this study, we mapped a defined virus attachment site to primary hepatocytes that is essential for infection. METHODS:We used purified virus particles from human carr...

journal_title：Gastroenterology

authors： Glebe D,Urban S,Knoop EV,Cag N,Krass P,Grün S,Bulavaite A,Sasnauskas K,Gerlich WH

更新日期：2005-07-01 00:00:00

abstract：:A 61-yr-old woman was found to have multicentric hepatocellular carcinoma associated with clinical hyperthyroidism. Marked elevations in serum thyroid-stimulating hormone, T4, T3, and free T4 were documented. These values increased with tumor progression. It is postulated that this patient's hepatoma produced a substa...

journal_title：Gastroenterology

authors： Helzberg JH,McPhee MS,Zarling EJ,Lukert BP

更新日期：1985-01-01 00:00:00

abstract：BACKGROUND & AIMS:New serologic markers of inflammatory bowel disease may be useful for differentiating between Crohn's disease and ulcerative colitis and for disease stratification. We profiled sugar-binding antibodies to identify novel antiglycan antibodies that may be associated with inflammatory bowel disease. MET...

journal_title：Gastroenterology

authors： Dotan I,Fishman S,Dgani Y,Schwartz M,Karban A,Lerner A,Weishauss O,Spector L,Shtevi A,Altstock RT,Dotan N,Halpern Z

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND/AIMS:Despite putative roles of calcium in biliary physiology and gallstone formation, quantitative aspects of calcium binding to bile salt (BS) monomers, simple micelles, mixed micelles, and vesicles, which constitute the lipid aggregates in bile, remain unexplored. METHODS:Calcium activity was measured usi...

journal_title：Gastroenterology

authors： Donovan JM,Leonard MR,Batta AK,Carey MC

更新日期：1994-09-01 00:00:00

abstract：BACKGROUND & AIMS:Mutational inactivation of adenomatous polyposis coli (APC) is an early event in colorectal cancer (CRC) progression that affects the stability and increases the activity of β-catenin, a mediator of Wnt signaling. Progression of CRC also involves inactivation of signaling via transforming growth facto...

journal_title：Gastroenterology

authors： Freeman TJ,Smith JJ,Chen X,Washington MK,Roland JT,Means AL,Eschrich SA,Yeatman TJ,Deane NG,Beauchamp RD

更新日期：2012-03-01 00:00:00