Catabolism of chylomicron remnants in patients with previous acute pancreatitis.

abstract：BACKGROUND:The contribution of the crural diaphragm to the gastroesophageal high pressure zone (HPZ) may be important in prevention of gastroesophageal reflux. The purpose of this study was to investigate the manometric characteristics of the thoracoabdominal junction in patients after surgical removal of the lower eso...

journal_title：Gastroenterology

authors： Klein WA,Parkman HP,Dempsey DT,Fisher RS

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND & AIMS:The metabolic and urease responses of Helicobacter pylori to variations in gastric acidity are unknown. The aim of this study was to determine effects of changes of environmental pH on metabolism, urease activity, and survival of H. pylori in an unbuffered environment. METHODS:Bacterial metabolism an...

journal_title：Gastroenterology

authors： Rektorschek M,Weeks D,Sachs G,Melchers K

更新日期：1998-09-01 00:00:00

abstract：:Upper gut transit and motility among 10 symptomatic and 9 asymptomatic patients with Roux gastrectomy were compared with those among 10 healthy, unoperated controls. Gastric emptying of solids and Roux limb and small intestinal transit of liquids were assessed scintigraphically. Motor patterns in the Roux limb or heal...

journal_title：Gastroenterology

authors： Miedema BW,Kelly KA,Camilleri M,Hanson RB,Zinsmeister AR,O'Connor MK,Brown ML

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND & AIMS:Although ustekinumab is an effective therapy for moderate to severe Crohn's disease (CD), its effects on the microscopic manifestations of CD are unknown. METHODS:We evaluated the effects of ustekinumab on histologic CD activity in an analysis of data from 251 participants in phase 3 induction and ma...

journal_title：Gastroenterology

authors： Li K,Friedman JR,Chan D,Pollack P,Yang F,Jacobstein D,Brodmerkel C,Gasink C,Feagan BG,Sandborn WJ,Rutgeerts P,De Hertogh G

更新日期：2019-10-01 00:00:00

abstract：:The G-cell population in the pyloric antrum and proximal duodenum was studied quantitatively by immunofluorescence in specimens from 10 gastric and 12 duodenal ulcer patients. In both groups, G-cell density was highest in the pyloric antrum and much lower in the intermediate zone and proximal duodenum, and G-cell coun...

journal_title：Gastroenterology

authors： Takahashi T,Shimazu H,Yamagishi T,Tani M

更新日期：1980-03-01 00:00:00

abstract：BACKGROUND & AIMS:Histamine-producing enterochromaffin-like (ECL) cells play an integrative role in the regulation of acid secretion. Decreased mucosal histamine concentrations and increased levels of interleukin (IL) 1 beta, IL-6, and IL-8 have been detected in the gastric mucosa inflamed with Helicobacter pylori. The...

journal_title：Gastroenterology

authors： Prinz C,Neumayer N,Mahr S,Classen M,Schepp W

更新日期：1997-02-01 00:00:00

abstract：BACKGROUND & AIMS:Nonalcoholic fatty liver disease (NAFLD) is associated with increased risk of hepatic, cardiovascular, and metabolic diseases. High-protein diets, rich in methionine and branched chain amino acids (BCAAs), apparently reduce liver fat, but can induce insulin resistance. We investigated the effects of d...

journal_title：Gastroenterology

authors： Markova M,Pivovarova O,Hornemann S,Sucher S,Frahnow T,Wegner K,Machann J,Petzke KJ,Hierholzer J,Lichtinghagen R,Herder C,Carstensen-Kirberg M,Roden M,Rudovich N,Klaus S,Thomann R,Schneeweiss R,Rohn S,Pfeiffer AF

更新日期：2017-02-01 00:00:00

abstract：:The results of this study show that lower esophageal sphincter contractions occur during phases 2 and 3 of the gastric interdigestive migratory motor complex in humans. In one series of studies, esophageal, gastric, and duodenal pressures were monitored overnight for 12 h in 7 healthy, fasting subjects. A second group...

journal_title：Gastroenterology

authors： Dent J,Dodds WJ,Sekiguchi T,Hogan WJ,Arndorfer RC

更新日期：1983-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Prolonged lamivudine therapy is associated with treatment-resistant YMDD mutant hepatitis B virus (HBV). We evaluated the efficacy and safety of adding adefovir dipivoxil to lamivudine in 135 patients with chronic hepatitis B (CHB) and YMDD mutant HBV. METHODS:Ninety-five patients with compensated ...

journal_title：Gastroenterology

authors： Perrillo R,Hann HW,Mutimer D,Willems B,Leung N,Lee WM,Moorat A,Gardner S,Woessner M,Bourne E,Brosgart CL,Schiff E

更新日期：2004-01-01 00:00:00

abstract：:We compared the inhibition of food-stimulated gastric acid secretion and changes in serum concentrations of immunoreactive gastric inhibitory polypeptide and gastrin caused by: (a) duodenal perfusion of oleic acid, and (b) intravenous infusion of pure, natural, porcine gastric inhibitory, polypeptide in dogs with gast...

journal_title：Gastroenterology

authors： Yamagishi T,Debas HT

更新日期：1980-05-01 00:00:00

abstract：BACKGROUND & AIMS:Mutations in TP53, a tumor suppressor gene, are associated with prognosis of many cancers. However, the prognostic values of TP53 mutation sites are not known for patients with hepatocellular carcinoma (HCC) because of heterogeneity in their geographic and etiologic backgrounds. METHODS:TP53 mutation...

journal_title：Gastroenterology

authors： Woo HG,Wang XW,Budhu A,Kim YH,Kwon SM,Tang ZY,Sun Z,Harris CC,Thorgeirsson SS

更新日期：2011-03-01 00:00:00

abstract：BACKGROUND & AIMS:The integrin alpha(4)beta(7) mediates homing of effector/memory lymphocytes to the intestine and the mucosa-associated lymphoid tissue. This study examined the ability of alpha(4)beta(7)(hi) CD4(+) T lymphocytes to home to the stomach and their role in immunization-mediated protection against Helicoba...

journal_title：Gastroenterology

authors： Michetti M,Kelly CP,Kraehenbuhl JP,Bouzourene H,Michetti P

更新日期：2000-07-01 00:00:00

abstract：:Ursodeoxycholic acid, the 7 beta-hydroxy epimer of chenodeoxycholic acid, is more hydrophilic and less hepatotoxic than chenodeoxycholic acid. Because "lagodeoxycholic acid," the 12 beta-hydroxy epimer of deoxycholic acid, is also more hydrophilic than deoxycholic acid, it was hypothesized that it should also be less ...

journal_title：Gastroenterology

authors： Schmassmann A,Angellotti MA,Clerici C,Hofmann AF,Ton-Nu HT,Schteingart CD,Marcus SN,Hagey LR,Rossi SS,Aigner A

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND/AIMS:The frequency of colorectal adenomas, the precursor lesions for most cases of colorectal carcinoma, has been generally measured as prevalence rates of adenomas at autopsy or colonoscopy. The aim of this study was to estimate the incidence rate of adenomas and compare it with the adenoma recurrence rate....

journal_title：Gastroenterology

authors： Neugut AI,Jacobson JS,Ahsan H,Santos J,Garbowski GC,Forde KA,Treat MR,Waye J

更新日期：1995-02-01 00:00:00

abstract：:Although long-term parenteral nutrition is lifesaving in patients with intestinal failure, it is expensive and associated with serious complications such as catheter sepsis, venous occlusions, and liver failure and severely impairs the quality of life in the short bowel patients. Therefore, treatments that increase th...

journal_title：Gastroenterology

authors： Jeppesen PB

更新日期：2006-02-01 00:00:00

abstract：:Extracellular space and blood volume were measured using 82Br dilution and 51Cr-tagged erythrocytes in 24 tumor-free patients after total gastrectomy. Eleven of the patients suffered from early dumping. Age, blood volume, and extracellular space were significantly smaller in dumpers (P less than 0.05). The dumping sco...

journal_title：Gastroenterology

authors： Miholic J,Reilmann L,Meyer HJ,Körber H,Kotzerke J,Hecker H

更新日期：1990-10-01 00:00:00

abstract：BACKGROUND & AIMS:SPD476 (LIALDA in the US; MEZAVANT in the EU; otherwise known as MMX mesalamine; Shire Pharmaceuticals Inc., Wayne, PA, under license from Giuliani SpA, Milan, Italy) is a novel, once-daily, high-strength (1.2 g/tablet) formulation of mesalamine, utilizing MMX Multi Matrix System (MMX) technology desi...

journal_title：Gastroenterology

authors： Kamm MA,Sandborn WJ,Gassull M,Schreiber S,Jackowski L,Butler T,Lyne A,Stephenson D,Palmen M,Joseph RE

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND & AIMS:Alterations of hepatic cholesterol metabolism in patients with cholesterol gallstones are still controversial. This study investigated whether hepatic cholesterol metabolism is altered in Japanese patients with cholesterol gallstones. METHODS:In this systematic study of 24 middle-aged nonobese and no...

journal_title：Gastroenterology

authors： Ito T,Kawata S,Imai Y,Kakimoto H,Trzaskos JM,Matsuzawa Y

更新日期：1996-05-01 00:00:00

abstract：:This literature review and the recommendations therein were prepared for the American Gastroenterological Association Clinical Practice and Practice Economics committee. The paper was approved by the committee on May 16, 1999, and by the AGA governing board on July 18, 1999. ...

journal_title：Gastroenterology

authors： Zuckerman GR,Prakash C,Askin MP,Lewis BS

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND & AIMS:Patients with irritable bowel syndrome with diarrhea (IBS-D) have increased mucosal serotonin (5-hydroxytryptamine [5-HT]) availability, possibly because immune activation reduces activity of the 5-HT transporter (SERT). We investigated the relationship between mucosal and platelet SERT and immune act...

journal_title：Gastroenterology

authors： Foley S,Garsed K,Singh G,Duroudier NP,Swan C,Hall IP,Zaitoun A,Bennett A,Marsden C,Holmes G,Walls A,Spiller RC

更新日期：2011-05-01 00:00:00

abstract：:Severe cholestasis associated with long-term home parenteral nutrition is rare, and no treatment is known to be effective. This study shows a case of a patient who developed jaundice while receiving long-term home parenteral nutrition. Causes of jaundice, other than the patient's parenteral feedings, were excluded. Th...

journal_title：Gastroenterology

authors： Lindor KD,Burnes J

更新日期：1991-07-01 00:00:00

abstract：BACKGROUND & AIMS:Epithelial stem cells in the stomach are responsible for constant renewal of the epithelium through generation of multiple gastric cell lineages that populate the gastric glands. However, gastric stem or progenitor cells have not been well-characterized because of the lack of specific markers that per...

journal_title：Gastroenterology

authors： Qiao XT,Ziel JW,McKimpson W,Madison BB,Todisco A,Merchant JL,Samuelson LC,Gumucio DL

更新日期：2007-12-01 00:00:00

abstract：:Interstitial pneumonitis is an uncommon complication of low-dose methotrexate therapy in patients with psoriasis but occurs in 3%-5% of patients with rheumatoid arthritis. We found a higher incidence of interstitial pneumonitis in patients with primary biliary cirrhosis (14%) and describe its clinical manifestations, ...

journal_title：Gastroenterology

authors： Sharma A,Provenzale D,McKusick A,Kaplan MM

更新日期：1994-07-01 00:00:00

abstract：:A multicenter study was conducted on 173 patients with active, endoscopically proven duodenal ulcers (158 men, 15 women). They were randomly assigned, in a double-blind manner, to two groups: those receiving placebo capsules (91 patients) and those receiving capsules containing 100 microgram of 15(R)-15-methyl prostag...

journal_title：Gastroenterology

authors： Vantrappen G,Janssens J,Popiela T,Kulig J,Tytgat GN,Huibregtse K,Lambert R,Pauchard JP,Robert A

更新日期：1982-08-01 00:00:00

abstract：BACKGROUND/AIMS:Liver fat-storing cells (FSCs) actively proliferate and secrete extracellular matrix during liver injury. Platelet-derived growth factor (PDGF) is a potent mitogen for cultured FSCs. In the present study, we investigated the regulation of PDGF gene expression and production in cultured human liver FSCs....

journal_title：Gastroenterology

authors： Marra F,Choudhury GG,Pinzani M,Abboud HE

更新日期：1994-10-01 00:00:00

abstract：:A case of spontaneous rupture of a nonparasitic liver cyst, documented by serial computed tomography scans, is reported. The patient was closely followed clinically after the rupture of the cyst and was treated conservatively, without surgical intervention. No peritonitis developed. This unusual complication of nonpar...

journal_title：Gastroenterology

authors： Akriviadis EA,Steindel H,Ralls P,Redeker AG

更新日期：1989-07-01 00:00:00

abstract：BACKGROUND & AIMS:Alcoholic patients with and without chronic liver disease have a high incidence of infection with hepatitis C virus (HCV). Long-term ethanol consumption in mice has been associated with a strikingly reduced CD8(+) cytotoxic T-lymphocyte (CTL) response to HCV nonstructural proteins following DNA-based ...

journal_title：Gastroenterology

authors： Aloman C,Gehring S,Wintermeyer P,Kuzushita N,Wands JR

更新日期：2007-02-01 00:00:00

abstract：BACKGROUND & AIMS:Helicobacter pylori is believed to predispose to gastric cancer by inducing gastric atrophy and hypochlorhydria. First-degree relatives of patients with gastric cancer have an increased risk of developing gastric cancer. The aim of this study was to determine the prevalence of atrophy and hypochlorhyd...

journal_title：Gastroenterology

authors： El-Omar EM,Oien K,Murray LS,El-Nujumi A,Wirz A,Gillen D,Williams C,Fullarton G,McColl KE

更新日期：2000-01-01 00:00:00

abstract：BACKGROUND AND AIMS:The peptidyl prolyl isomerase Pin1 frequently is overexpressed in hepatocellular carcinoma (HCC). Hepatitis B virus (HBV) is the most common etiologic agent in HCC, and its encoded X-protein (HBx) is oncogenic and possesses a serine-proline motif that may bind Pin1. The role of Pin1 in hepatocarcino...

journal_title：Gastroenterology

authors： Pang R,Lee TK,Poon RT,Fan ST,Wong KB,Kwong YL,Tse E

更新日期：2007-03-01 00:00:00

abstract：:The possibility that chronic uremia renders the gastric mucosa more susceptible to acid injury was investigated. A rat model of chronic renal failure was induced by subtotal nephrectomy. [H+] back-diffusion across the mucosa, following intragastric perfusion of 0.15N HCl or 15% ethanol in 0.15N HCl, was significantly ...

journal_title：Gastroenterology

authors： Quintero E,Kaunitz J,Nishizaki Y,De Giorgio R,Sternini C,Guth PH

更新日期：1992-12-01 00:00:00