Discrete regional analysis of norepinephrine, dopamine, choline acetyltransferase and glutamic acid decarboxylase in the brain of the newborn and pubescent monkey.

abstract：:Fenfluramine, an anorexigenic drug, lowers serotonin (5-hydroxytryptamine) and 5-hydroxyindoleacetic acid levels in brain, spinal fluid, and blood, and has been used as a treatment for autism. Fenfluramine's mode of action is unknown. We present evidence from chromatography and nuclear magnetic resonance spectroscopy ...

journal_title：Brain research bulletin

authors： Root-Bernstein RS,Westall FC

更新日期：1984-01-01 00:00:00

abstract：:Some C57Bl/6 mice become obese, whereas others remain lean when raised on a high-fat diet. The mechanisms underlying this interindividual susceptibility to diet-induced obesity remain unknown. Because hypothalamus plays a major role in the regulation of body weight, this study was conducted to identify the differences...

journal_title：Brain research bulletin

authors： Xin X,Storlien LH,Huang XF

更新日期：2000-07-01 00:00:00

abstract：:Since the groundbreaking work of Ramon y Cajal, the cerebellar Purkinje cell has always represented an ideal model for studying the organization, development and function of synaptic circuits. Purkinje cells receive distinct types of glutamatergic and GABAergic synapses, each characterized by exquisite sub-cellular an...

journal_title：Brain research bulletin

authors： Sassoè-Pognetto M,Patrizi A

更新日期：2017-03-01 00:00:00

abstract：:A high correlation between alcohol use and smoking has long been suggested by epidemiological data. We examined the potential behavioral interactions between ethanol and nicotine using ethanol-induced motor incoordination as the test response in mice. Effect of pretreatment of various doses of (-)-nicotine, (-)-cotini...

journal_title：Brain research bulletin

authors： Dar MS,Li C,Bowman ER

更新日期：1993-01-01 00:00:00

abstract：:Intracerebral hemorrhage (ICH) is a common neurological disease, causing severe disability and even deaths. Stem cell transplantation has been increasingly used in stroke therapy, and neural stem cells (NSCs) are a good source for stem cell transplantation. However, the regulatory mechanism of NSCs remains unclear. In...

journal_title：Brain research bulletin

authors： Sun Z,Wu K,Gu L,Huang L,Zhuge Q,Yang S,Wang Z

更新日期：2020-11-01 00:00:00

abstract：:To investigate nitric oxide production in the brain of the EL mouse, an inbred mutant strain of the ddY mouse that is susceptible to convulsive seizures, we measured whole brain nitric oxide metabolites, and counted the number of nitric oxide-producing cells in the parietal cortex and striatum. Nitric oxide metabolite...

journal_title：Brain research bulletin

authors： Uchida M,Nagatomo I,Akasaki Y,Tominaga M,Hashiguchi W,Kuchiiwa S,Nakagawa S,Takigawa M

更新日期：1999-11-01 00:00:00

abstract：:To determine whether or not prolactin, as well as ACTH, was involved in the control of adrenal weight and steroid release, lesions in the median eminence which had previously resulted in impaired steroid release and atrophy of the adrenal were placed in animals in which the plasma prolactin was allowed to rise as a re...

journal_title：Brain research bulletin

authors： Marubayashi U,McCann SM,Antunes-Rodrigues J

更新日期：1987-11-01 00:00:00

abstract：:Data from clinical investigations and laboratory fundings have provided preliminary evidence for the effectiveness and safety of acupuncture therapy in depression. However, the mechanisms underlying the antidepressant response of acupuncture are not fully elucidated. To elucidate the potential effects of acupuncture f...

journal_title：Brain research bulletin

authors： Wang Y,Jiang H,Meng H,Lu J,Li J,Zhang X,Yang X,Zhao B,Sun Y,Bao T

更新日期：2017-09-01 00:00:00

abstract：:Gamma-aminobutyric acid (GABA) is an important inhibitory neurotransmitter in the mature brain. At an early developmental period, it acts in an excitatory manner that influences many processes of proliferation, migration, and differentiation of the neurons. Previous evidence indicated that manipulation of the GABAergi...

journal_title：Brain research bulletin

authors： Naderipoor P,Amani M,Abedi A,Sakhaie N,Sadegzadeh F,Saadati H

更新日期：2021-01-10 00:00:00

abstract：:Permanent cannulae for intracerebroventricular (ICV) infusion were implanted bilaterally in cats following stereotaxic procedures. After colonic temperature was recorded for a one-hour baseline, a 300 microliter ICV infusion was given of CSF control vehicle, 1:100 dilution of W3110 E. coli endotoxin (10(8) organisms/m...

journal_title：Brain research bulletin

authors： Rezvani AH,Denbow DM,Myers RD

更新日期：1986-01-01 00:00:00

abstract：:Recent investigations of the nucleus ambiguus (NA) have attempted to identify motoneurons associated with the branchiomeric muscles of the larynx and pharynx. However, relatively little attention has been directed to the levator veli palatini muscle (LVP) which is critical in respiration, deglutition and eustachian tu...

journal_title：Brain research bulletin

authors： van Loveren H,Saunders MC,Keller JT

更新日期：1983-09-01 00:00:00

abstract：:Interferon-alpha (IFN-alpha, 2.0 x 10(4) units) was bilaterally microinjected into the medial preoptic area and anterior hypothalamus in conscious rats treated 10 min prior with an opioid receptor antagonist, naloxone (NLX, 2 mg/kg, IM) or a prostaglandin synthetase inhibitor, acetaminophen (ACAP, 25 mg/kg, IM). The I...

journal_title：Brain research bulletin

authors： Nakashima T,Murakami T,Murai Y,Hori T,Miyata S,Kiyohara T

更新日期：1995-01-01 00:00:00

abstract：BACKGROUND:Traditional Medicine Practices (TMP) which are premised on indigenous knowledge and experiences within a local context of the culture and environment, are common place in low income countries. In Africa and in Uganda specifically, nearly 80% of the Ugandan population relies on TMP for the care of their menta...

journal_title：Brain research bulletin

authors： Abbo C,Odokonyero R,Ovuga E

更新日期：2019-02-01 00:00:00

abstract：:Long chain fatty acids (FA) and 2-monoacylglycerols (MG) are produced by lipoprotein lipase (LPL) from plasma triacylglycerols (TG) in capillaries of adipose tissue and transported to adipocytes for TG synthesis. It is widely proposed FA may be transported in cells by FA-binding protein. Mode of transport of MG has re...

journal_title：Brain research bulletin

authors： Scow RO,Blanchette-Mackie EJ

更新日期：1991-09-01 00:00:00

abstract：:The aim of this study was to investigate whether the histamine H1-receptor blocker, chlorpheniramine (CPA), has a reinforcing effect in goldfish. We used a place-preference procedure in an aquarium with two chambers colored black and white. On day 1, the animals were placed in the test chamber for 10 min for habituati...

journal_title：Brain research bulletin

authors： Mattioli R,Nelson CA,Huston JP,Spieler RE

更新日期：1998-01-01 00:00:00

abstract：:Simple tandem repeats represent more than 1% of the human genome: occasionally they exhibit intergenerational expansibility and are associated with neuromuscular diseases. In transgenic mice the same sequences elicit similar symptoms, but do not expand. We have searched for di-, tri-, and tetra-repeats in the publishe...

journal_title：Brain research bulletin

authors： Astolfi P,Bellizzi D,Losso MA,Sgaramella V

更新日期：2001-10-01 00:00:00

abstract：:The objective of this study was to determine the organization of coactivation in the arm and shoulder muscles. Normal human subjects made alternate movements of a joint in the horizontal plane, either adduction-abduction of the second finger and shoulder, ulnar-radial deviation of the wrist, or extension-flexion of th...

journal_title：Brain research bulletin

authors： Yamazaki Y,Suzuki M,Ohkuwa T,Itoh H

更新日期：2003-02-15 00:00:00

abstract：:A cDNA for Drosophila choline acetyltransferase (ChAT) was expressed in E. coli and the recombinant enzyme partially purified. Kinetic analysis yielded the following constants for the recombinant enzyme; KmAcCoA = 29 microM, KmCoA = 25 microM, Kmcholine = 330 microM, and Kmacetylcholine = 2 mM. The recombinant Drosoph...

journal_title：Brain research bulletin

authors： Carbini L,Rodriguez G,Hersh LB

更新日期：1990-01-01 00:00:00

abstract：:Prenatal exposure of mice to heroin (SC injection of 10mg/kg to the dams on gestational days 9-18) resulted at adulthood in behavioral deficits related to septohippocampal cholinergic innervation accompanied with both presynaptic and postsynaptic cholinergic hyperactivity; including an increase membrane PKC activity, ...

journal_title：Brain research bulletin

authors： Yaniv SP,Naor Z,Yanai J

更新日期：2004-05-30 00:00:00

abstract：:The effects of intrathecally (i.t.) administered naloxone or glibenclamide, a blocker of adenosine triphosphate-sensitive potassium (KATP) channels, on the antinociception produced by i.t. apomorphine were observed by an integrated electromyogram measurement of hindlimb flexor reflex in lightly pentobarbital-anestheti...

journal_title：Brain research bulletin

authors： Hu WM,Kang YM,Qiao JT

更新日期：1999-02-01 00:00:00

abstract：:The acute effects of 2-deoxy-D-glucose (2-DG)-induced glucoprivic feeding on the anorectic drug recognition site and Na+K(+)-ATPase in the brain were examined in adult rats and in lean and genetically obese mice. The marked hyperglycemia and the induction of feeding caused by the administration of 2-DG to satiated rat...

journal_title：Brain research bulletin

authors： Angel I,Hauger RL,Giblin BA,Paul SM

更新日期：1992-02-01 00:00:00

abstract：:Previously, we have showed that the cholecystokinin (CCK)-A receptor expression in hypothalamus is closely related with the responsiveness of electroacupuncture (EA)-mediated analgesic effects in rats. In order to confirm this observation more directly in vivo, the EA-mediated analgesic effects are compared between Ot...

journal_title：Brain research bulletin

authors： Lee GS,Han JB,Shin MK,Hong MC,Kim SW,Min BI,Bae H

更新日期：2003-12-15 00:00:00

abstract：:Rats were tested in the elevated plus-maze test of anxiety after a probe injection of chlordiazepoxide (CDP 5 mg/kg) following short-term (5 days) or long-term (20 days) pretreatment with 5 or 20 mg/kg/day. After short-term pretreatment with either dose, the probe dose had anxiolytic effects (it increased the % number...

journal_title：Brain research bulletin

authors： File SE,Baldwin HA,Aranko K

更新日期：1987-11-01 00:00:00

abstract：:Although originally developed as a research tool for studying glial-glial and glial-axonal interactions, the technique of transplanting glial cell into the central nervous system has more recently been employed as a potential means for repairing persistent demyelination in clinical disease. It has now been clearly est...

journal_title：Brain research bulletin

authors： Franklin RJ

更新日期：2002-04-01 00:00:00

abstract：:Electrophysiologic response characteristics of mouse sciatic nerve and spinal cord were investigated following CNS infection with the temperature-sensitive (ts) vesicular stomatitis virus (VSV) mutant G31 KS5. Measurements were obtained before clinical symptoms of the virus-induced CNS disease appeared. Sciatic nerve ...

journal_title：Brain research bulletin

authors： Gerren RA,Johnson TC

更新日期：1994-01-01 00:00:00

abstract：:Fibroblast growth factor 9 (FGF9) is a member of the fibroblast growth factor family and is widely expressed in the central nervous system (CNS). However, it is not clear how the working mechanism of FGF9 is involved in cerebellar development. To address this question, we deleted the Fgf9 gene specifically in GABAergi...

journal_title：Brain research bulletin

authors： Guo M,Chen H,Duan W,Li Z,Li Y,Ma Y,Xu X,Yi L,Bi Y,Liu Y,Zhang J,Li C

更新日期：2020-01-01 00:00:00

abstract：:Methoxetamine (MXE) is a novel psychoactive compound (NPS) that emerged in 2010 as a substitute for the dissociative anaesthetic ketamine. MXE has a reputation of carrying a lower risk of harm than ketamine, however a number of deaths have been reported. Currently very little is known about the psychopharmacological e...

journal_title：Brain research bulletin

authors： Horsley RR,Lhotkova E,Hajkova K,Jurasek B,Kuchar M,Palenicek T

更新日期：2016-09-01 00:00:00

abstract：:A simple procedure for recording of diaphragmatic electromyographic activity in awake, freely behaving animals is described. This procedure produces highly stable recording of muscle activity for very long periods. Because of its ease of use, the procedure has become the technique of choice for acute recording in our ...

journal_title：Brain research bulletin

authors： Chang FC,Harper RM

更新日期：1989-03-01 00:00:00

abstract：:Field-evoked potentials from the main olfactory bulb in response to stimulation of the olfactory nerve and lateral olfactory tract were measured without and with conditioning stimulation of the locus coeruleus noradrenergic system. The locus coeruleus conditioning stimulus suppressed or inhibited the late components o...

journal_title：Brain research bulletin

authors： Perez H,Hernandez A,Almli CR

更新日期：1987-06-01 00:00:00

abstract：:Wnt signaling plays an important role in the adult brain function and its dysregulation has been implicated in some neurodegenerative pathways. Despite the functional role of the Wnt signaling in adult neural circuits, there is currently no evidence regarding the relationships between exogenously Wnt signaling activat...

journal_title：Brain research bulletin

authors： Ortiz-Matamoros A,Arias C

更新日期：2018-05-01 00:00:00