Abstract:
:One year's experience in screening for congenital hypothyroidism in Greece is reported. Thyroid stimulating hormone (TSH) determination by a radioimmunoassay on dried blood spots was selected as the screening method. During the first year of screening 75,879 newborn infants were tested from Guthrie blood spots taken on the 5th day of life. Eighteen cases of primary congenital hypothyroidism with serum TSH levels over 100 microIU/ml were detected, giving an incidence of 1: 4200. One case had already been diagnosed clinically. Replacement treatment was started between the 22nd and the 50th days of life.
journal_name
Eur J Pediatrjournal_title
European journal of pediatricsauthors
Mengreli C,Kassiou K,Tsagaraki S,Pantelakis Sdoi
10.1007/BF00441314subject
Has Abstractpub_date
1981-10-01 00:00:00pages
185-7issue
2eissn
0340-6199issn
1432-1076journal_volume
137pub_type
杂志文章abstract::Gradenigo's syndrome (GS) is a rare disease characterised by the triad otitis media, pain in the region innervated by the first and the second division of trigeminal nerve and abducens nerve palsy. Septic sinus thrombosis is one of the most frequent and relevant complication of GS; it is often due to persistent damage...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-009-1047-4
更新日期:2010-04-01 00:00:00
abstract::Two siblings became very ill after BCG inoculation in the newborn period. A generalized BCG infection was assumed from the clinical symptomatology and the histological findings. Later on the boy suffered from enteric salmonellosis and osteomyelitis caused by the same organism, and as a todler he had intestinal pseudot...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00445481
更新日期:1976-02-04 00:00:00
abstract::Indomethacin treatment for 1 week monitored by drug level determinations was evaluated in 32 preterm infants with symptomatic patent ductus arteriosus (sPDA). Inter- and intra-individual indomethacin dispositions varied considerably with the need for marked dosage adjustments to maintain the drug level within the prop...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02343219
更新日期:1987-03-01 00:00:00
abstract::In a case of hypochondrogenesis, abnormal fat deposits were found in the chondrocytes, by anatomopathological and by ultrastructural examination. In the cultured fibroblast we were unable to demonstrate abnormal lipid loading. Our case could be isolated from other types of lethal congenital chondrodysplasias--especial...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00443377
更新日期:1983-06-01 00:00:00
abstract::A girl suffering from marked muscular hypotonia, severe statomotor and mental retardation, bilateral optic atrophy with chorioretinal degeneration, convulsions and a moderate compensated metabolic acidosis is described. Screening for metabolic disorders revealed massive 3-methylglutaconic with 3-methylglutaric aciduri...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442306
更新日期:1985-03-01 00:00:00
abstract::Malignant thymoma was found in an 8-year-old Japanese boy with growth hormone (GH) deficiency who had received GH therapy for 3 years and 5 months. There may be a possible relationship between the occurrence of malignant thymoma and GH therapy. ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02073374
更新日期:1993-10-01 00:00:00
abstract::The main ethical imperative of all paediatric actions is the demand to do everything "in the best interests of children". Relevant guidelines can be derived from the UN Declaration on the Rights of Children, whereupon every child has the fundamental right to life and dignity, and is entitled to optimal medical care. P...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-005-0002-2
更新日期:2006-02-01 00:00:00
abstract:UNLABELLED:This study compared the foot morphology of Spanish schoolchildren based on their body mass index and age and analyzed whether body mass index affects the child's foot development at primary school. Cross-sectional study of 1,032 schoolchildren (497 boys and 535 girls), 6-12 years old. Height and weight were ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-013-1944-4
更新日期:2013-05-01 00:00:00
abstract::W170, i.e., the work rate at a heart frequency of 170 beats per minute, and maximal oxygen uptake were determined in one performance in 20 boys and 23 girls from 6 to 16 years of age on a bicycle ergometer. The results were related to normal values according to age and height. In different age and sex groups correlati...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00463741
更新日期:1976-06-08 00:00:00
abstract::Congenital nephrotic syndrome (CNS) is a heterogeneous group of diseases with different causes and prognoses. Two thirds of cases of NS in the first year of life are caused by mutations in four genes (NPHS1, NPHS2, WT1, and LAMB2). The mutation of WT1 gene can lead to Denys-Drash syndrome (DDS). We report on female mo...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1497-3
更新日期:2012-01-01 00:00:00
abstract::Forty newborns with severe shock and disseminated intravascular coagulation were randomized for treatment with heparin or placebo. Mortality was equal in both groups. The heparin group required significantly shorter periods of artificial ventilation. The coagulation system improved faster, and the coagulation pattern ...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章,随机对照试验
doi:10.1007/BF00444754
更新日期:1980-01-01 00:00:00
abstract::We examined the long-term outcome in 111 children who had convulsions during shigellosis and were followed for 3-18 years after the incident. No deaths or persistent motor deficits occurred as sequellae. Poor coordination of fine hand movements were noted in 3.3% of the 92 children who had no pre-existing neurological...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02106298
更新日期:1990-01-01 00:00:00
abstract:INTRODUCTION:Impaired vitamin K status in cystic fibrosis (CF) has been considered as a newly emerged pathogenetic factor for reduced bone mineral density (BMD). OBJECTIVES:Our aim was to evaluate the effectiveness of vitamin K supplementation in managing bone formation abnormalities in children and adolescents with C...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0132-1
更新日期:2006-08-01 00:00:00
abstract::The development of visual acuity and stereopsis was studied in 321 boys and 340 girls aged between 5 and 10 years. Visual acuity was assessed by the E test and a modified version of the STYCAR test, stereo acuity by the Lang-Stereo test [17]. Both vision tests showed an increase in the median visual acuity between the...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02429046
更新日期:1986-12-01 00:00:00
abstract::Perinatal transmission remains the main cause of HIV infection in the pediatric population. Treatment of HIV-infected children has become less of a problem in resource-rich countries with a remarkable decrease of perinatal infections, resulting in an effective prevention of mother-to-child transmission and antiretrovi...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/s00431-008-0914-8
更新日期:2009-04-01 00:00:00
abstract::An asthmatic child is presented who developed a cushingoid appearance with evidence of adrenal suppression and growth impairment while on low dose inhaled topical steroids. When the inhaled steroids were replaced by inhaled sodium cromoglycate his adrenal function recovered while his appearance and growth returned to ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02093730
更新日期:1991-04-01 00:00:00
abstract::Health-related quality of life (HRQOL) is an important indicator of the burden of illness in moderate-to-severe plaque psoriasis. This study evaluated self-reported generic HRQOL among pediatric patients with moderate-to-severe plaque psoriasis based on pooled baseline clinical trial data and compared them to four com...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1587-2
更新日期:2012-03-01 00:00:00
abstract::Thrombocypenic purpura was noted in a 3-year-old Japanese girl with an active varicella infection. The administration of intravenous gamma globulin (IVG) drastically improved bleeding manifestations as well as the active varicella infection. We believe that IVG should be the first choice of therapy for thrombocytopeni...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441611
更新日期:1987-09-01 00:00:00
abstract:UNLABELLED:The symptoms of urinary tract infections in infants are very non-specific and have historically included prolonged hyperbilirubinaemia. We studied the results of routine urine samples in 319 infants with prolonged jaundice. Convincing findings of UTI was not found in any of these children even if one of them...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-015-2499-3
更新日期:2015-07-01 00:00:00
abstract::Children with symptomatic hypoglycemia and asymptomatic hypoglycemia-prone children were shown to differ in the degree of ketosis after a 20 h fast. In the latter children the close negative correlation between ketone body levels and glucose levels yielded a regression line against which the former children's data cou...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442403
更新日期:1980-06-01 00:00:00
abstract::Iodine deficiency is well documented in Belgium in adults including pregnant women, adolescents, schoolchildren, and neonates, but no data are available in the age group 6 months-3 years. We investigated the status of iodine nutrition in 111 healthy subjects in this age group in an attempt to evaluate the risk of brai...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s004310000707
更新日期:2001-04-01 00:00:00
abstract:UNLABELLED:Over the last decade, substantial progress has been made in the field of pertussis research. This includes better understanding of virulence mechanisms and their influence on the pathogenicity of Bordetella pertussis, increased awareness of the broad spectrum of disease and more insight into the host's immun...
journal_title:European journal of pediatrics
pub_type: 杂志文章,评审
doi:10.1007/pl00008429
更新日期:2001-04-01 00:00:00
abstract::Acid-base disturbances have been usually evaluated with the traditional Henderson-Hasselbach method and Stewart's physiochemical approach by quantifying anions of tissue acids (TA). It is hypothesized that an increase in tissue acids during metabolic acidosis would cause a compensatory decrease in the plasma chloride ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-011-1666-4
更新日期:2012-06-01 00:00:00
abstract::In 166 full term, small-for-gestational-age (FT-SGA), 53 preterm, appropriate-for-gestational-age (PT-AGA), 27 PT-SGA and 206 FT-AGA infants a neurological examination at the age of 6 years was carried out. Data were collected on behaviour and school achievement. Major and minor neurological abnormalities were more fr...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00441967
更新日期:1988-06-01 00:00:00
abstract:UNLABELLED:The importance of ultrasonography after the first febrile urinary tract infection has been recently challenged. The aim of this study was to evaluate the role of ultrasonography in detection of significant non-reflux abnormalities in the kidneys and the urinary tract, and to determine whether these findings ...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0113-4
更新日期:2006-08-01 00:00:00
abstract::The daily excretion of C-peptide in the urine was measured in 105 healthy infants and children from birth to 14 years of age. For technical reasons no studies were performed from 1-3 years of age. The excretion of C-peptide showed a close positive correlation with age and weight. The relationship with weight was alrea...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF00442133
更新日期:1985-01-01 00:00:00
abstract::Pulmonary arterial hypertension is characterised by the presence of pulmonary hypertension (mean pulmonary artery pressure >25 mmHg at rest or >30 mmHg during exercise ) and normal pulmonary wedge pressure (<12 mmHg). Several risk factors for pulmonary arterial hypertension have been described. In the absence of any f...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-002-1012-y
更新日期:2002-10-01 00:00:00
abstract:UNLABELLED:To assess the role of dexamethasone treatment as a cause of systemic hypertension and associated complications, blood pressure was registered prospectively before, during and after a 4-week dexamethasone course in 22 neonates with chronic lung disease. In all patients systolic blood pressure rose significant...
journal_title:European journal of pediatrics
pub_type: 临床试验,杂志文章
doi:10.1007/BF01957907
更新日期:1996-07-01 00:00:00
abstract:OVERVIEW:In newborns with symptomatic congenital cytomegalovirus (CMV) infection, neuroimaging is the best available predictor of neurodevelopmental outcome. Cerebrospinal fluid (CSF) findings in congenital CMV infection have seldom been described. Neonates with central nervous system infections present high CSF Beta(2...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/s00431-006-0160-x
更新日期:2006-09-01 00:00:00
abstract:UNLABELLED:A 14-year-old boy developed acute quadriplegia, associated with sensory impairment and bowel and urinary dysfunction. MRI of the cervical cord showed diffuse increased signal intensity on T2-weighted images with gadolinium-diethylenetriamine penta-acetic acid enhancement. Based on the clinical presentation a...
journal_title:European journal of pediatrics
pub_type: 杂志文章
doi:10.1007/BF02072107
更新日期:1995-05-01 00:00:00