Dexamethasone associated systemic hypertension in low birth weight babies with chronic lung disease.

Abstract:

UNLABELLED:To assess the role of dexamethasone treatment as a cause of systemic hypertension and associated complications, blood pressure was registered prospectively before, during and after a 4-week dexamethasone course in 22 neonates with chronic lung disease. In all patients systolic blood pressure rose significantly during treatment (median rise 34 mm Hg, range 4-->59 mm Hg), without complications attributable to hypertension. In all but one patient blood pressure returned to pretreatment values within 2 weeks after stopping dexamethasone treatment. CONCLUSION:Dexamethasone induced hypertension is transient, even after a 4-week course, and is not associated with hypertensive complications, so treatment is not necessary. When hypertension persists after dexamethasone withdrawal other causes should be considered.

journal_name

Eur J Pediatr

authors

Smets K,Vanhaesebrouck P

doi

10.1007/BF01957907

subject

Has Abstract

pub_date

1996-07-01 00:00:00

pages

573-5

issue

7

eissn

0340-6199

issn

1432-1076

journal_volume

155

pub_type

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