Arterial effects of palmitic, linoleic and acetoacetic acid.

abstract：BACKGROUND AND AIMS:The impact of treatment strategies on outcomes in patients with stable coronary artery disease (CAD) and type 2 diabetes mellitus (T2DM) according to presenting angina has not been rigorously assessed. METHODS:We performed a patient-level pooled-analysis (n = 5027) of patients with stable CAD and T...

journal_title：Atherosclerosis

authors： Mancini GBJ,Boden WE,Brooks MM,Vlachos H,Chaitman BR,Frye R,Bittner V,Hartigan PM,Dagenais GR

更新日期：2018-10-01 00:00:00

abstract：:To test if the prevalence of genetic risk factors for coronary heart disease (CHD) is low in individuals who have reached an extremely old age, the allele frequencies of apolipoprotein E (apo E) and B (apo B) polymorphisms and plasma lipoprotein(a) levels were investigated in nonagenarians and in younger control group...

journal_title：Atherosclerosis

authors： Kervinen K,Savolainen MJ,Salokannel J,Hynninen A,Heikkinen J,Ehnholm C,Koistinen MJ,Kesäniemi YA

更新日期：1994-01-01 00:00:00

abstract：:The relationships between plasma lecithin:cholesterol acyltransferase (LCAT) mass concentrations and lipids, apolipoprotein, and lipoprotein subfraction concentrations were studied in men assigned at random to a one-year exercise program (n = 48) and to a sedentary control condition (n = 31). Exercise training did not...

journal_title：Atherosclerosis

authors： Williams PT,Albers JJ,Krauss RM,Wood PD

更新日期：1990-05-01 00:00:00

abstract：:The objective of this study was to examine frequency of familial defective apo-B-100 (FDB, R3500Q mutation) in probands with the phenotype of familial hypercholesterolemia (FH) and in the general population of 40-year-old subjects in Slovakia and to characterize their lipid and clinical criteria and to compare the fre...

journal_title：Atherosclerosis

authors： Gasparovic J,Basistová Z,Fábryová L,Wsólová L,Vohnout B,Raslová K,Slovak MED PED FH group.

更新日期：2007-10-01 00:00:00

abstract：:Individuals who are physically fit or engage in regular physical activity have a lower incidence of cardiovascular disease and risk of mortality. We conducted a large-scale controlled trial of interventions to decrease cardiovascular risk factors, during which we assessed the effect of a workplace-based intervention p...

journal_title：Atherosclerosis

authors： Naito M,Nakayama T,Okamura T,Miura K,Yanagita M,Fujieda Y,Kinoshita F,Naito Y,Nakagawa H,Tanaka T,Ueshima H,HIPOP-OHP Research Group.

更新日期：2008-04-01 00:00:00

abstract：:Inflammatory response genes may influence life span or quality at advanced ages. Using data from the population-based cardiovascular health study (CHS) cohort, we examined the associations between promoter polymorphisms of several inflammation and thrombosis genes with longevity. We ascertained genotypes for interleuk...

journal_title：Atherosclerosis

authors： Reiner AP,Diehr P,Browner WS,Humphries SE,Jenny NS,Cushman M,Tracy RP,Walston J,Lumley T,Newman AB,Kuller LH,Psaty BM

更新日期：2005-07-01 00:00:00

abstract：:Adhesion molecules and cytokines are involved in the pathogenesis of intimal injury in atherosclerosis but their relationship with endothelial function remains unclear. The objectives of this study were to examine the effects of atorvastatin on soluble adhesion molecules, interleukin-6 (IL-6) and brachial artery endot...

journal_title：Atherosclerosis

authors： Nawawi H,Osman NS,Annuar R,Khalid BA,Yusoff K

更新日期：2003-08-01 00:00:00

abstract：:DNA probes for all eight of the major apolipoprotein genes are now available. The chromosomal location, the basic structure and in many cases the nucleotide sequences of the normal genes are known. Common DNA polymorphisms of all of the genes have been detected. These have been been used in a number of ways to investi...

journal_title：Atherosclerosis

authors： Humphries SE

更新日期：1988-08-01 00:00:00

abstract：OBJECTIVE:Olive oil protects against cardiovascular disease but the underlying mechanism is still unclear. We speculated that olive oil could inhibit oxidative stress, which is believed to be implicated in the atherosclerotic process. METHODS AND RESULTS:Post-prandial oxidative stress and endothelial dysfunction were ...

journal_title：Atherosclerosis

authors： Carnevale R,Pignatelli P,Nocella C,Loffredo L,Pastori D,Vicario T,Petruccioli A,Bartimoccia S,Violi F

更新日期：2014-08-01 00:00:00

abstract：:An inverse relationship between moderate alcohol consumption and coronary artery disease (CAD) has been observed in several epidemiologic studies. Whether improvement of endothelial function is involved in this beneficial effect is unknown. We investigated endothelial function of the brachial artery in 108 men with CA...

journal_title：Atherosclerosis

authors： Teragawa H,Fukuda Y,Matsuda K,Higashi Y,Yamagata T,Matsuura H,Chayama K

更新日期：2002-11-01 00:00:00

abstract：BACKGROUND AND OBJECTIVE:Serum γ-glutamyl transferase (GGT) levels are known to be positively associated with obesity. We aimed at verifying an association between baseline GGT levels and the development of obesity in Korean men. PATIENTS AND METHODS:This prospective cohort study was performed on 18,510 initially non-...

journal_title：Atherosclerosis

authors： Suh YJ,Park SK,Choi JM,Ryoo JH

更新日期：2013-04-01 00:00:00

abstract：:Human serum paraoxonase (PON1) is an HDL-associated enzyme involved in the protection of lipoproteins from oxidation. A polymorphism at position 192 (Gln/Arg) influences its activity in a substrate-dependent manner. The aim of the present study was to evaluate, in vivo, the contribution of the PON1-192 polymorphism to...

journal_title：Atherosclerosis

authors： Gnasso A,Motti C,Irace C,Di Gennaro I,Pujia A,Leto E,Ciamei M,Crivaro A,Bernardini S,Federici G,Cortese C

更新日期：2002-10-01 00:00:00

abstract：BACKGROUND:Mutations in the LDL receptor gene are the major cause of familial hypercholesterolaemia (FH) but it has been previously shown that the simple finding of a variation in the coding sequence of the LDLR does not confirm that it is the actual cause of FH. The pathogenicity of five missense alterations in the LD...

journal_title：Atherosclerosis

authors： Silva S,Alves AC,Patel D,Malhó R,Soutar AK,Bourbon M

更新日期：2012-11-01 00:00:00

abstract：:Incorporation of 125I-labeled cholesterol ester rich lipoproteins from cholesterol fed rabbits into normal rabbit aorta in vitro was inhibited by heparin, lecithin, and collagenase and by succinylation of the lipoprotein. Aortic uptake of lipoprotein was increased by neuraminidase, proteases, lipase, and beta-glucuron...

journal_title：Atherosclerosis

authors： Day CE

更新日期：1976-11-01 00:00:00

abstract：BACKGROUND AND AIMS:High concentrations of low density lipoprotein (LDL) triglycerides have been associated with prevalent angiographic coronary artery disease. The present analysis was designed to investigate the association of LDL triglycerides with cardiovascular mortality and to explore possible mechanisms that may...

journal_title：Atherosclerosis

authors： Silbernagel G,Scharnagl H,Kleber ME,Delgado G,Stojakovic T,Laaksonen R,Erdmann J,Rankinen T,Bouchard C,Landmesser U,Schunkert H,März W,Grammer TB

更新日期：2019-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH) was rarely diagnosed in Latvia before 2015, when the Latvian Registry of FH (LRFH) was established. Here, we report the first experience of the LRFH over three years (2015-2017). METHODS:The LRFH is an ongoing nationwide, dynamic, long-term prospective cohort. The...

journal_title：Atherosclerosis

authors： Latkovskis G,Saripo V,Gilis D,Nesterovics G,Upena-Roze A,Erglis A

更新日期：2018-10-01 00:00:00

abstract：:Several reports have shown that lipoprotein(a) is associated with ischemic diseases. Two characteristics might explain this association. Firstly, Lp(a) is an LDL-like lipoprotein which may be implicated in the atherosclerotic process and secondly, Lp(a) possesses an additional apolipoprotein(a) whose structure is clos...

journal_title：Atherosclerosis

authors： Delplanque B,Beaumont V,Lemort N,Beaumont JL

更新日期：1993-05-01 00:00:00

abstract：:We investigated the effects of estrogen and simvastatin, administered both alone and in combination, on the plasma lipid levels and lipoprotein-related enzymes in 45 postmenopausal women with type IIa hypercholesterolemia. They received 0.625 mg conjugated equine estrogen (n=15), 5 mg simvastatin (n=15), or the combin...

journal_title：Atherosclerosis

authors： Wakatsuki A,Okatani Y,Ikenoue N

更新日期：2000-05-01 00:00:00

abstract：OBJECTIVE:The goal of the study was to examine possible sex-related differences in the clinical characteristics and risk factors in Japanese patients with peripheral arterial disease (PAD). METHODS:Sex-related differences in clinical profiles, risk factors and treatments were examined in 730 consecutive patients with ...

journal_title：Atherosclerosis

authors： Kumakura H,Kanai H,Araki Y,Kasama S,Sumino H,Ito T,Iwasaki T,Takayama Y,Ichikawa S,Fujita K,Nakashima K,Minami K

更新日期：2011-12-01 00:00:00

abstract：BACKGROUND:Lipoprotein distribution of non-cholesterol sterols was studied to evaluate in which lipoproteins they are carried in type 2 diabetes with body weight ranging from normal to overweight. METHODS:Serum and lipoprotein squalene and non-cholesterol sterols were quantitated with gas-liquid chromatography in 33 d...

journal_title：Atherosclerosis

authors： Simonen PP,Gylling H,Miettinen TA

更新日期：2007-09-01 00:00:00

abstract：:We describe the cardiovascular state of a 60-year-old homozygous patient with familial HDL deficiency (Tangier disease). The patient was examined by coronary angiography and intravascular ultrasound because of chest pain at rest and on exertion. We found a normal left ventricular function, moderately diffuse coronary ...

journal_title：Atherosclerosis

authors： Walter M,Kerber S,Fechtrup C,Seedorf U,Breithardt G,Assmann G

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND AND AIMS:Cardiovascular disease (CVD) and cancer are the two leading causes of death in smokers. Lung cancer screening is recommended in a large proportion of smokers. We examined the implication of coronary artery calcium (CAC) score (quantitative and qualitative) for cardiovascular disease (CVD), coronary ...

journal_title：Atherosclerosis

authors： Mirbolouk M,Kianoush S,Dardari Z,Miedema MD,Shaw LJ,Rumberger JA,Berman DS,Budoff MJ,Rozanski A,Al-Mallah MH,McEvoy JW,Nasir K,Blaha MJ

更新日期：2020-02-01 00:00:00

abstract：:Studies were performed to determine if serum bilirubin, when combined with various lipid and lipoprotein risk factors, enhances our ability to predict coronary artery disease (CAD). This hypothesis was tested in a retrospective study of 644 middle-aged males who had undergone coronary angiography. The traditional risk...

journal_title：Atherosclerosis

authors： Schwertner HA,Fischer JR Jr

更新日期：2000-06-01 00:00:00

abstract：:Abundant data is present to implicate oxidatively modified low-density lipoprotein (oxLDL) in enhanced atherogenesis. Among the factors involved in LDL oxidation, an important role has been attributed to human 15-lipoxygenase (LO) and its murine analog 12-LO. The expression of these peroxidizing enzymes is under the c...

journal_title：Atherosclerosis

authors： George J,Mulkins M,Shaish A,Casey S,Schatzman R,Sigal E,Harats D

更新日期：2000-12-01 00:00:00

abstract：BACKGROUND:In acute myocardial infarction (AMI) treated conservatively or with thrombolysis, marked increases of C-reactive protein (CRP) and fibrinogen have been observed. No data are however available concerning a possible relation between CRP and fibrinogen levels on admission and markers of infarct size after obtai...

journal_title：Atherosclerosis

authors： De Sutter J,De Buyzere M,Gheeraert P,Van de Wiele C,Voet J,De Pauw M,Dierckx R,De Backer G,Taeymans Y

更新日期：2001-07-01 00:00:00

abstract：OBJECTIVE:Atherosclerosis is the main underlying cause of the majority of cardiovascular events. Although cardiovascular diseases (CVD) are a major challenge in both males and females, gender specific differences in the prevalence of CVD have been observed. This may indicate that there are differences in the developmen...

journal_title：Atherosclerosis

authors： van den Oord SCH,van der Burg J,Akkus Z,Bosch JG,van Domburg RT,Sijbrands EJG,van der Steen AFW,Schinkel AFL

更新日期：2014-04-01 00:00:00

abstract：BACKGROUND AND AIMS:Chronic intermittent hypoxia (CIH) exposure causes atherosclerosis, although the underlying mechanisms are poorly understood. This study defines the role of endothelial intrinsic NF-κB signaling in the atherogenic response to CIH. METHODS:We created ApoE-ECI-κBmt mice that are deficient in the apol...

journal_title：Atherosclerosis

authors： Song D,Fang G,Mao SZ,Ye X,Liu G,Miller EJ,Greenberg H,Liu SF

更新日期：2018-03-01 00:00:00

abstract：:A combined gross and histologic study carried out on 270 selected male subjects with the common type of distribution of the coronary arteries revealed a natural resistance to intimal thickening and plaque development exhibited by the left main coronary artery and by the first centimeter of the right coronary artery. T...

journal_title：Atherosclerosis

authors： Velican C,Velican D

更新日期：1984-02-01 00:00:00

abstract：:Coating a silica surface with the isolated lipoprotein receptor proteoheparan sulfate (HS-PG) from arterial endothelium and vascular matrices and adding both the atherogenic VLDL/IDL/LDL lipid fraction in its native composition and Ca(2+) ions, we could observe in vitro the earliest stages of atherosclerotic plaque de...

journal_title：Atherosclerosis

authors： Rodríguez M,Ringstad L,Schäfer P,Just S,Hofer HW,Malmsten M,Siegel G

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVE:Matrix metalloproteinases (MMPs) are implicated in the pathogenesis of atherosclerosis. However, the relationship between blood levels of MMPs and the extent of carotid atherosclerosis remains uncertain. We assessed blood levels of active MMPs in relation to the extent of carotid plaque formation and intima-m...

journal_title：Atherosclerosis

authors： Lien LM,Hsieh YC,Bai CH,Chen WH,Chiu HC,Hsieh FI,Shyu KG,Chiou HY,Hsu CY

更新日期：2010-10-01 00:00:00