Associations of lecithin: cholesterol acyltransferase (LCAT) mass concentrations with exercise, weight loss, and plasma lipoprotein subfraction concentrations in men.

abstract：:The association between serum selenium concentration and a number of coronary heart disease risk factors is studied in 364 males from southern Italy participating in the Olivetti Heart Study. Selenium correlates positively and significantly with serum cholesterol (r = 0.120; P = 0.022), and this positive association p...

journal_title：Atherosclerosis

authors： Jossa F,Trevisan M,Krogh V,Farinaro E,Giumetti D,Fusco G,Galasso R,Panico S,Frascatore S,Mellone C

更新日期：1991-04-01 00:00:00

abstract：OBJECTIVE:Only a few studies have investigated the changes in carotid intima-media thickness (IMT) over time, and uncertainties remain on the underlying mechanisms linking depression and subclinical atherosclerosis. We carried out a prospective cohort study to evaluate whether depression is associated with changes in c...

journal_title：Atherosclerosis

authors： Pizzi C,Costa GM,Santarella L,Flacco ME,Capasso L,Bert F,Manzoli L

更新日期：2014-04-01 00:00:00

abstract：OBJECTIVE:The apolipoprotein E mimetic peptide Ac-hE18A-NH(2), capable of reducing plasma cholesterol and possessing anti-inflammatory properties, was compared with the well-studied anti-atherogenic apoA-I mimetic peptide 4F for reducing lesion formation in female apoE null mice with already existing lesions. METHODS ...

journal_title：Atherosclerosis

authors： Nayyar G,Garber DW,Palgunachari MN,Monroe CE,Keenum TD,Handattu SP,Mishra VK,Anantharamaiah GM

更新日期：2012-10-01 00:00:00

abstract：:Methionine is converted by the transmethylation/transsulfuration pathway to homocysteine which may exert atherogenic effects by several mechanisms, including lipid peroxidation. Therefore, the excessive dietary methionine may induce the development of atherosclerosis. To test this hypothesis, plasma and aortic thiobar...

journal_title：Atherosclerosis

authors： Toborek M,Kopieczna-Grzebieniak E,Drózdz M,Wieczorek M

更新日期：1995-06-01 00:00:00

abstract：BACKGROUND AND AIMS:Sarpogrelate, a 5-hydroxytryptamine type 2A antagonist, is a potential antiplatelet agent. We performed a randomized study to evaluate the effect of sarpogrelate on vascular health in Korean patients with diabetes. METHODS:Forty diabetic patients aged 58.6 ± 6.8 years with 10-75% coronary artery st...

journal_title：Atherosclerosis

authors： Lee DH,Chun EJ,Hur JH,Min SH,Lee JE,Oh TJ,Kim KM,Jang HC,Han SJ,Kang DK,Kim HJ,Lim S

更新日期：2017-02-01 00:00:00

abstract：OBJECTIVE:A direct correlation between blood glucose levels and the microvascular complications of diabetes is well established. However, the effects of hyperglycaemia on the vasa vasorum, a microvascular network which surrounds and supplies the walls of large arteries, is not known. The objective of this study is to i...

journal_title：Atherosclerosis

authors： Veerman KJ,Venegas-Pino DE,Shi Y,Khan MI,Gerstein HC,Werstuck GH

更新日期：2013-04-01 00:00:00

abstract：:Even when administered at a comparatively low level, dietary cholesterol produces significant changes in the properties of plasma lipoproteins in rats, particularly the d less than or equal to 1.006 g/ml fraction (VLDL). The occurrence of these changes is promoted by dietary casein. To test the hypothesis that these d...

journal_title：Atherosclerosis

authors： Eklund A,Sjöblom L,Ostlund-Lindqvist AM

更新日期：1986-11-01 00:00:00

abstract：UNLABELLED:Previous studies have suggested altered triglyceride (TG) storage in patients with abdominal obesity and blood lipid disorders. OBJECTIVE:We hypothesized that women with abdominal obesity and a dysmetabolic profile have low DGAT activity in their abdominal fat compartments. METHODS:Paired omental (OM) and ...

journal_title：Atherosclerosis

authors： Côté JA,Nadeau M,Leboeuf M,Blackburn L,Tchernof A

更新日期：2014-03-01 00:00:00

abstract：BACKGROUND AND AIMS:The European Society of Cardiology developed prediction models (SCORE) for low- and high-risk populations in the European countries. However, whether or not these models are valid in different ethnicities is unknown. We aimed to evaluate the performance of the low-risk SCORE model in the general Jap...

journal_title：Atherosclerosis

authors： Sawano M,Kohsaka S,Okamura T,Inohara T,Sugiyama D,Watanabe M,Nakamura Y,Higashiyama A,Kadota A,Okud N,Murakami Y,Ohkubo T,Fujiyoshi A,Miura K,Okayama A,Ueshima H,National Integrated Project for Prospective Observation of

更新日期：2016-09-01 00:00:00

abstract：:Non-alcoholic fatty liver disease (NAFLD) is the hepatic manifestation of the metabolic syndrome and the incidence of which is rising rapidly due to the increasing epidemic of obesity in both adults and children. The initial accumulation of fat followed by subsequent inflammation is central to the development of liver...

journal_title：Atherosclerosis

authors： Than NN,Newsome PN

更新日期：2015-03-01 00:00:00

abstract：BACKGROUND AND AIMS:Results from prospective studies evaluating the relationship between elevated lipoprotein-associated phospholipase A2 (Lp-PLA2) activity and incident peripheral arterial disease (PAD) have been mixed. We investigated whether higher Lp-PLA2 levels are associated with increased risk of incident PAD an...

journal_title：Atherosclerosis

authors： Garg PK,Norby FL,Polfus LM,Boerwinkle E,Gibbs RA,Grove ML,Folsom AR,Garimella PS,Matsushita K,Hoogeveen RC,Ballantyne CM

更新日期：2018-01-01 00:00:00

abstract：:The mechanisms of inflammation responsible for the myocardial tissue damage seen after an acute myocardial infarction (AMI) have not been clearly identified. Recent lines of evidence, demonstrating depressed sera levels of individual complement components in patients after myocardial infarction, have suggested involve...

journal_title：Atherosclerosis

authors： Langlois PF,Gawryl MS

更新日期：1988-03-01 00:00:00

abstract：:The effects of platelet factors on human umbilical venous endothelial cell DNA-synthesis at various serum concentrations were studied. While [3H]thymidine uptake of these cells was almost linearly related to the concentration of serum in the culture medium, no significant differences were found at any serum level betw...

journal_title：Atherosclerosis

authors： Thorgeirsson G,Robertson AL Jr

更新日期：1978-10-01 00:00:00

abstract：:In general, plasma concentrations of high density lipoproteins (HDL) are inversely related to the incidence of coronary artery disease. One exception to this trend is individuals with apolipoprotein A-I(Milano) (apo A-IM), a molecular variant of apo A-I, which results in very low plasma apo A-I and HDL-cholesterol lev...

journal_title：Atherosclerosis

authors： Chiesa G,Stoltzfus LJ,Michelagnoli S,Bielicki JK,Santi M,Forte TM,Sirtori CR,Franceschini G,Rubin EM

更新日期：1998-01-01 00:00:00

abstract：:Genome-wide association studies (GWASs) have identified several risk loci for coronary artery calcification. Four single-nucleotide polymorphisms (SNPs, rs1537370, rs1333049, rs2026458 and rs9349379) were associated with coronary artery calcification with P values less than 5 × 10(-8) in GWASs. It is unclear if these ...

journal_title：Atherosclerosis

authors： Zhang Y,Wang L,Zhang Z,Zhang Z,Zhou S,Cao L,Cai B,Liu K,Bai W,Xie X,Fan W,Liu X,Lu G,Xu G

更新日期：2015-08-01 00:00:00

abstract：BACKGROUND AND AIMS:Familial hypercholesterolemia (FH), which leads to premature cardiovascular events, still remains underrecognized and undertreated in most countries. Untreated FH individuals aged 20-39 years are at 100-fold higher risk of mortality from coronary heart disease compared to those of a general populati...

journal_title：Atherosclerosis

authors： Mickiewicz A,Chmara M,Futema M,Fijalkowski M,Chlebus K,Galaska R,Bandurski T,Pajkowski M,Zuk M,Wasag B,Limon J,Rynkiewicz A,Gruchala M

更新日期：2016-06-01 00:00:00

abstract：:Apolipoprotein E (apoE) exerts prominent anti-inflammatory effects and undergoes recycling by target cells. We previously reported that the peptide Ac-hE18A-NH(2), composed of the receptor binding domain (LRKLRKRLLR) of apoE covalently linked to the Class A amphipathic peptide 18A, dramatically lowers plasma cholester...

journal_title：Atherosclerosis

authors： Datta G,White CR,Dashti N,Chaddha M,Palgunachari MN,Gupta H,Handattu SP,Garber DW,Anantharamaiah GM

更新日期：2010-01-01 00:00:00

abstract：:Oxidation of low density lipoprotein (LDL) leads to more rapid uptake by arterial wall macrophages and foam cell formation. Inhibiting LDL oxidation may impede these processes and offers a new mechanism to retard atherogenesis. The 21-aminosteroids, derived from methylprednisolone, are potent inhibitors of free radica...

journal_title：Atherosclerosis

authors： Fisher M,Levine PH,Doyle EM,Arpano MM,Hoogasian JJ

更新日期：1991-10-01 00:00:00

abstract：:Prolonged exposure of rats to cigarette smoke resulted in significant alterations in the metabolism of lipids. There was a significant increase in the concentration of cholesterol, triglycerides and phospholipids in most of the tissues, particularly the heart, aorta and lungs. Cholesterol, triglycerides and phospholip...

journal_title：Atherosclerosis

authors： Latha MS,Vijayammal PL,Kurup PA

更新日期：1988-04-01 00:00:00

abstract：BACKGROUND:Persons with cerebral palsy (CP) have mobility limitations and may be at increased risk for cardiovascular disease (CVD). AIMS:To determine the feasibility of assessing novel CVD risk indicators and to identify predictors of CVD risk in a clinic-based group of adults with CP. METHODS:In an observational st...

journal_title：Atherosclerosis

authors： McPhee PG,Gorter JW,Cotie LM,Timmons BW,Bentley T,MacDonald MJ

更新日期：2015-12-01 00:00:00

abstract：BACKGROUND AND AIMS:The role of circular RNAs (circRNAs) in coronary artery disease (CAD) remains elusive. The aim of the present study was to profile circRNAs expression in CAD patients and assess diagnostics biomarkers for CAD. METHODS:The circRNA profiles of 24 CAD patients and 7 controls were assessed by microarra...

journal_title：Atherosclerosis

authors： Wang L,Shen C,Wang Y,Zou T,Zhu H,Lu X,Li L,Yang B,Chen J,Chen S,Lu X,Gu D

更新日期：2019-07-01 00:00:00

abstract：BACKGROUND AND AIMS:Oxidative modification of lipoproteins is a crucial step in atherosclerosis development. Isotopic-reinforced polyunsaturated fatty acids (D-PUFAs) are more resistant to reactive oxygen species-initiated chain reaction of lipid peroxidation than regular hydrogenated (H-)PUFAs. We aimed at investigati...

journal_title：Atherosclerosis

authors： Berbée JFP,Mol IM,Milne GL,Pollock E,Hoeke G,Lütjohann D,Monaco C,Rensen PCN,van der Ploeg LHT,Shchepinov MS

更新日期：2017-09-01 00:00:00

abstract：:The vascular endothelial cell (EC) plays an essential role in the pathogenesis of inflammation, transplant rejection and tumour metastasis. Most research on vascular ECs uses human umbilical vein endothelial cells (HUVECs). However, HUVECs are derived from immune-naive foetal tissue, and show significant functional di...

journal_title：Atherosclerosis

authors： Tan PH,Chan C,Xue SA,Dong R,Ananthesayanan B,Manunta M,Kerouedan C,Cheshire NJ,Wolfe JH,Haskard DO,Taylor KM,George AJ

更新日期：2004-04-01 00:00:00

abstract：:Mild hyperhomocysteinemia is considered an important risk factor for vascular disease. A common polymorphism (677C-->T) in the methylenetetrahydrofolate reductase (MTHFR) gene is associated with a decreased enzyme activity and consequent higher circulating levels of homocysteine. We hypothesized that the serum levels ...

journal_title：Atherosclerosis

authors： Pisciotta L,Cortese C,Gnasso A,Liberatoscioli L,Pastore A,Mannucci L,Irace C,Federici G,Bertolini S

更新日期：2005-04-01 00:00:00

abstract：AIMS:Apolipoprotein C-III (apoC-III) has been recognized as a useful marker of triglyceride-rich lipoproteins (TRLs) metabolism and proposed as an indicator of prognosis for coronary risk in healthy subjects. We studied cross-sectionally in a population having low cholesterol levels, but a high prevalence of the metabo...

journal_title：Atherosclerosis

authors： Onat A,Hergenç G,Sansoy V,Fobker M,Ceyhan K,Toprak S,Assmann G

更新日期：2003-05-01 00:00:00

abstract：:Over 200 risk factors for cardiovascular disease (CVD) have now been identified. Among these, the three most important are (1) abnormal lipids, including the fact that there are more than 15 types of cholesterol-containing lipoproteins and four different types of triglyceride-rich particles, some of which are very ath...

journal_title：Atherosclerosis

authors： Castelli WP

更新日期：1996-07-01 00:00:00

abstract：:The Del allele of the apolipoprotein B (apoB) signal peptide (SP) insertion/deletion (Ins/Del) polymorphism has been shown to be associated with elevated plasma levels of apoB, cholesterol and low density lipoprotein. It was the aim of the present study to analyse the relation of this gene variation to the risk of cor...

journal_title：Atherosclerosis

authors： Gardemann A,Ohly D,Fink M,Katz N,Tillmanns H,Hehrlein FW,Haberbosch W

更新日期：1998-11-01 00:00:00

abstract：OBJECTIVE:α-Linolenic acid (ALA), the vegetable n-3 fatty acid, appears to have antiatherosclerotic properties akin to those of marine n-3 fatty acids. A prior study in a US population with low fish intake showed an inverse association between ALA intake and carotid plaque. We examined the association between the ALA s...

journal_title：Atherosclerosis

authors： Sala-Vila A,Cofán M,Núñez I,Gilabert R,Junyent M,Ros E

更新日期：2011-01-01 00:00:00

abstract：AIMS:We have examined the cross-sectional relationship between insulin resistance, the metabolic syndrome and haemostatic and inflammatory markers. METHODS AND RESULTS:We carried out the study in 2722 non-diabetic men aged 60-79 years with no history of coronary heart disease or stroke and who were not on warfarin tre...

journal_title：Atherosclerosis

authors： Wannamethee SG,Lowe GD,Shaper AG,Rumley A,Lennon L,Whincup PH

更新日期：2005-07-01 00:00:00

abstract：BACKGROUND:Tissue proportions of long chain n-6 [especially arachidonic acid (AA)] and n-3 fatty acids [FA; eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) acids], or some ratio of these may be markers of risk for coronary heart disease (CHD). The purpose of this paper is to evaluate the published associatio...

journal_title：Atherosclerosis

authors： Harris WS,Poston WC,Haddock CK

更新日期：2007-07-01 00:00:00