Evaluation of spasmolytic activity of clausmarin-A. a novel coumarin from Clausena pentaphylla (Roxb.) DC.

Abstract:

:Crude ethanolic (50%) extracts of five species of Clausena exhibited varying degrees of spasmolytic activity on the isolated guinea-pig ileum preparation. The aerial parts of Clausena pentaphylla had maximum activity. Its active principle clausmarin-A, a novel coumarin terpenoid, was evaluated in detail for spasmolytic activity in various in vivo and in vitro test models. The activity of clausmarin A compared favourably with that of papaverine.

journal_name

J Ethnopharmacol

authors

Patnaik GK,Dhawan BN

doi

10.1016/0378-8741(82)90001-0

subject

Has Abstract

pub_date

1982-09-01 00:00:00

pages

127-37

issue

2

eissn

0378-8741

issn

1872-7573

pii

0378-8741(82)90001-0

journal_volume

6

pub_type

杂志文章
  • Preventive effect of Abelmoschus manihot (L.) Medik. on bone loss in the ovariectomised rats.

    abstract::Because the biggest culprit in pathogenesis of osteoporosis is oestrogen deficiency, hormone replacement therapy remained the mainstay for prevention. However most of postmenopausal women are more inclined to use natural alternative. We thus investigated the ability of Abelmoschus manihot, a herbal medicine to prevent...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2005.01.047

    authors: Puel C,Mathey J,Kati-Coulibaly S,Davicco MJ,Lebecque P,Chanteranne B,Horcajada MN,Coxam V

    更新日期:2005-05-13 00:00:00

  • Angiogenic efficacy of simplified 2-herb formula (NF3) in zebrafish embryos in vivo and rat aortic ring in vitro.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Diabetic foot ulceration results in high risk of lower extremity amputation, and represents a significant health care expenditure worldwide. Radix Astragali (RA) and Radix Rehmanniae (RR) are widely used Chinese medicinal herbs in treating diabetes, and have shown positive effects in enha...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.11.031

    authors: Tse HY,Hui MN,Li L,Lee SM,Leung AY,Cheng SH

    更新日期:2012-01-31 00:00:00

  • Ethnobotany and antibacterial activity of some plants used in traditional medicine of Zapotitlán de las Salinas, Puebla (México).

    abstract::The village of Zapotitlán de las Salinas is situated in the Valley of Tehuacán-Cuicatlán, Puebla, Mexico. Plant species used by the local inhabitants to treat gastrointestinal diseases were identified using ethnobotanical, ethnographic and taxonomic methods. Out of 119 interviews, 44 plant species were registered, of ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(03)00213-7

    authors: Hernández T,Canales M,Avila JG,Duran A,Caballero J,Romo de Vivar A,Lira R

    更新日期:2003-10-01 00:00:00

  • Investigation of some Hypericum species native to Southern of Brazil for antiviral activity.

    abstract::Three plant species, Hypericum connatum, Hypericum caprifoliatum, Hypericum polyanthemum (Guttiferae), growing in Southern of Brazil were chemically investigated and tested for their antiviral activity against feline immunodeficiency virus (FIV). The chemical analysis revealed the presence of polyphenolic compounds su...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(01)00314-2

    authors: Schmitt AC,Ravazzolo AP,von Poser GL

    更新日期:2001-10-01 00:00:00

  • Is there an industrial future for phytopharmaceutical drugs? An outline of UNIDO programmes in the sector.

    abstract::Although a substantial proportion of the health-care expenditure of developing countries is spent on the acquisition of drugs, this is only sufficient to serve about a quarter of their population. Therefore it is inconceivable that WHO's goal of HEALTH FOR ALL by the year 2000 could even be approached without consider...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90121-s

    authors: Wijesekera RO

    更新日期:1991-04-01 00:00:00

  • Mode of action of Buddleja cordata verbascoside against Staphylococcus aureus.

    abstract::We evaluate the mode of action of verbascoside obtained from Buddleja cordata against Staphylococcus aureus by killing kinetics and incorporation of precursors methods. Verbascoside induced lethal effect on S. aureus, by affecting protein synthesis and inhibiting leucine incorporation. ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(98)00203-7

    authors: Avila JG,de Liverant JG,Martínez A,Martínez G,Muñoz JL,Arciniegas A,Romo de Vivar A

    更新日期:1999-07-01 00:00:00

  • Linking resource supplies and price drivers: Lessons from Traditional Chinese Medicine (TCM) price volatility and change, 2002-2017.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Worldwide, one of the drivers of substitution and adulteration is the cost of the natural resources (plants, animals, fungi) that are ingredients of traditional medicines. Relatively few studies have been done that link prices of traditional medicine ingredients to what drives changes in ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2018.10.010

    authors: Cunningham AB,Long X

    更新日期:2019-01-30 00:00:00

  • Antimicrobial activities of southern Nepalese medicinal plants.

    abstract::In an ethnopharmacological screening of selected medicinal plants used in Nepal, methanol extracts from 20 plant species were assayed for activity against eleven strains of bacteria and four strains of fungi. Duplicate assays were conducted with and without exposure to ultraviolet (UV)-A radiation to test for light-ac...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(95)01335-0

    authors: Taylor RS,Edel F,Manandhar NP,Towers GH

    更新日期:1996-02-01 00:00:00

  • Antioxidant and anti-inflammatory effect of Asphodelus microcarpus methanolic extracts.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Asphodelus microcarpus is an important medicinal plant belonging to family Liliaceae. This plant is used in traditional medicine to treat abscesses by local application of the powder; the roots are used against white spots, and specifically used for ear pain. AIM OF THE STUDY:The aim of ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.111914

    authors: Mayouf N,Charef N,Saoudi S,Baghiani A,Khennouf S,Arrar L

    更新日期:2019-07-15 00:00:00

  • Enigma of drug-induced altered states of consciousness among the !Kung Bushmen of the Kalahari Desert.

    abstract::This article examines data presented in Katz' book, Boiling Energy: Community Healing among the Kalahari Kung, particularly with regard to plant drugs present in the community during the 1968 visit. The author argues that the similarity of the Bushman trance state, kia and that of drug-induced altered states of consci...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(86)90168-6

    authors: Dobkin De Rios M

    更新日期:1986-03-01 00:00:00

  • Oral hypoglycaemic, antihyperglycaemic and antidiabetic activities of Sri Lankan Broken Orange Pekoe Fannings (BOPF) grade black tea (Camellia sinensis L.) in rats.

    abstract:UNLABELLED:ETHNOPHARMCOLOGICAL RELEVANCE: Sri Lankan traditional practitioners recommend the consumption of black tea infusion (BTI) made from Camellia sinensis L. plant for regulation of glycaemia. However, they do not specify the grade of tea and their origin (i.e., agroclimatic elevation) and as such many prediabeti...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.02.035

    authors: Abeywickrama KR,Ratnasooriya WD,Amarakoon AM

    更新日期:2011-05-17 00:00:00

  • The scorpion in Spanish folk medicine: a review of traditional remedies for stings and its use as a therapeutic resource.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:While scorpionism is not a serious public health problem in Spain, traditional Spanish knowledge has retained a large number of plant-based and animal-based remedies for scorpion stings. Additionally, this arthropod plays an important role in the treatment of its own sting and has become ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2012.12.033

    authors: González JA,Vallejo JR

    更新日期:2013-03-07 00:00:00

  • Evidence of anti-inflammatory and antinociceptive activities of Plinia edulis leaf infusion.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Plinia edulis (Vell.) Sobral (Myrtaceae) is native and endemic to the Brazilian Atlantic Rainforest. Popularly known as "cambucá", it has been used in folk medicine for the treatment of stomach disorders, diabetes, bronchitis, inflammation and as tonic. Although there are numerous records...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.07.001

    authors: Azevedo LF,Silva SMD,Navarro LB,Yamaguchi LF,Nascimento CGO,Soncini R,Ishikawa T

    更新日期:2016-11-04 00:00:00

  • Utilization of the extract of Cedrus deodara (Roxb. ex D.Don) G. Don against the biofilm formation and the expression of virulence genes of cariogenic bacterium Streptococcus mutans.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Cedrus deodara (Roxb. ex D.Don) G. Don is applied as anti-inflammatory and anti-infection agents in folklore medicine. AIM OF THE STUDY:The present study aimed to assess the antimicrobial activity of Cedrus deodara (Roxb. ex D.Don) G. Don extract (CDE) against Streptococcus mutans biofil...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112856

    authors: Zhang Z,Lyu X,Xu Q,Li C,Lu M,Gong T,Tang B,Wang L,Zeng W,Li Y

    更新日期:2020-07-15 00:00:00

  • Anxiolytic effect of an extract of Salvia miltiorrhiza Bunge (Danshen) in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Salvia miltiorrhiza Bunge (Danshen), a traditional Chinese medicine, has demonstrated in modern studies for its pharmacological activities in treatments of CNS disorders like insomnia, dysphoria. However, its application on anxiolytic effect from the ethanol extract of Salvia miltiorrhiza...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.113285

    authors: Lin YS,Peng WH,Shih MF,Cherng JY

    更新日期:2021-01-10 00:00:00

  • Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Fructus Alpinia zerumbet (FAZ), a dry and ripe fruit of Alpinia zerumbet (Pers.) Burtt. et Smith, is widely used as a spice to treat cardiovascular diseases in clinic as a miao folk medicine in Guizhou Province of China. Essential oil extracted from FAZ (EOFAZ) is the key bioactive ingred...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.03.011

    authors: Ji YP,Shi TY,Zhang YY,Lin D,Linghu KG,Xu YN,Tao L,Lu Q,Shen XC

    更新日期:2019-06-12 00:00:00

  • Toxicity studies in mice of ethanol extracts of Foeniculum vulgare fruit and Ruta chalepensis aerial parts.

    abstract::Acute (24-h) and chronic (90-day) oral toxicity studies on the ethanolic extracts of Foeniculum vulgare fruit and Ruta chalepensis aerial parts were carried out in mice. Acute dosages were 0.5, 1.0 and 3 g/kg while the chronic dosage was 100 mg/kg per day of extract. All external morphological, haematological and sper...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90034-b

    authors: Shah AH,Qureshi S,Ageel AM

    更新日期:1991-09-01 00:00:00

  • Ficus spp. (fig): ethnobotany and potential as anticancer and anti-inflammatory agents.

    abstract::This review explores medieval, ancient and modern sources for ethnopharmacological uses of Ficus (fig) species, specifically for employment against malignant disease and inflammation. The close connection between inflammatory/infectious and cancerous diseases is apparent both from the medieval/ancient merging of these...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2008.06.025

    authors: Lansky EP,Paavilainen HM,Pawlus AD,Newman RA

    更新日期:2008-09-26 00:00:00

  • HPLC-based activity profiling for antiplasmodial compounds in the traditional Indonesian medicinal plant Carica papaya L.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Leaf decoctions of Carica papaya have been traditionally used in some parts of Indonesia to treat and prevent malaria. Leaf extracts and fraction have been previously shown to possess antiplasmodial activity in vitro and in vivo. MATERIALS AND METHODS:Antiplasmodial activity of extracts ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.05.050

    authors: Julianti T,De Mieri M,Zimmermann S,Ebrahimi SN,Kaiser M,Neuburger M,Raith M,Brun R,Hamburger M

    更新日期:2014-08-08 00:00:00

  • Hepatoprotective effect of Gan Kang Yuan against chronic liver injury induced by alcohol.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gan Kang Yuan (GKY) is a compound medicine formulated on the basis of traditional Chinese medicine (TCM). It was composed of Herba Cistanchis (Roucongrong), Radix Puerariae (Gegen), Radix Astragali (Huangqi), Fructus Schisandrae (Wuweizi) and Radix Glycyrrhizae (Gancao). AIM:The purpose ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.06.033

    authors: Guo Y,Zhao Q,Cao L,Zhao B

    更新日期:2017-08-17 00:00:00

  • Antinociceptive, genotoxic and histopathological study of Heliopsis longipes S.F. Blake in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:H. longipes S.F. Blake (Asteraceae) is a Mexican plant, whose roots are traditionally used as a condiment, as a mouth anesthetic, and as an antiparasitic. Affinin is the alkamide present in higher amounts in the roots of H. longipes. AIM OF THE STUDY:To date, there are no published studi...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.04.037

    authors: Cariño-Cortés R,Gayosso-De-Lucio JA,Ortiz MI,Sánchez-Gutiérrez M,García-Reyna PB,Cilia-López VG,Pérez-Hernández N,Moreno E,Ponce-Monter H

    更新日期:2010-07-20 00:00:00

  • The efficacy of Chinese herbal medicines on acute coronary syndrome with renal insufficiency after percutaneous coronary intervention.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Fufang Chuanxiong capsule consists of Angelica sinensis radix and Chuanxiong rhizome, which are used in the traditional Chinese medicine for the treatment of coronary artery disease, and Xinyue capsule is composed of panax quinquefolius saponin extracted from leaves and stems of Panax qui...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,多中心研究,随机对照试验

    doi:10.1016/j.jep.2019.112354

    authors: Zhang DW,Wang SL,Wang PL,Du JP,Gao ZY,Wang CL,Xu H,Shi DZ

    更新日期:2020-02-10 00:00:00

  • Antimicrobial activity of extracts of three major plants from the Chihuahuan desert.

    abstract::Dilution methods were employed to determine the effect of ethanolic extracts of Agave lecheguilla Torr. (Agavaceae), Baccharis glutinosa Pers. (Compositae) and Larrea tridentata (DC.) Cov. (Zygophyllaceae) on growth of yeasts, molds and bacteria. The three extracts analyzed showed good antimicrobial activity against m...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(96)84802-1

    authors: Verástegui MA,Sánchez CA,Heredia NL,García-Alvarado JS

    更新日期:1996-07-05 00:00:00

  • In vitro anti-prostate cancer and ex vivo antiangiogenic activity of Vernonia guineensis Benth. (Asteraceae) tuber extracts.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Prostate cancer is a major problem worldwide and affects most men above the age of forty-five. Vernonia guineensis Benth. (Asteraceae) root decoction is used in folk medicine in Cameroon to treat a number of ailments including prostate cancer. The aim of this study was to provide a prelim...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.03.021

    authors: Toyang NJ,Wabo HK,Ateh EN,Davis H,Tane P,Kimbu SF,Sondengam LB,Bryant J

    更新日期:2012-06-14 00:00:00

  • Maternal-fetal repercussions of Phyllanthus niruri L. treatment during rat pregnancy.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Phyllanthus niruri is a well-known plant for its therapeutic purposes to treat various diseases, being widely used by the population, mainly by women. However, there is no scientific confirmation of the effects of use during pregnancy. AIM OF THE STUDY:Evaluating the effect of Phyllanthu...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112728

    authors: Paula VG,Cruz LL,Sene LB,Gratão TB,Soares TS,Moraes-Souza RQ,Damasceno DC,Volpato GT

    更新日期:2020-05-23 00:00:00

  • On the anti-inflammatory and anti-phospholipase A(2) activity of extracts from lanostane-rich species.

    abstract::We have studied extracts from three species rich in lanostane triterpenes for their activity against different in vivo models of inflammation induced by TPA, EPP and PLA(2). The inhibitory effect against PLA(2) in vitro was also studied. When the Poria cocos extract was tested against PLA(2)-induced mouse paw edema, i...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(00)00276-2

    authors: Giner-Larza EM,Máñez S,Giner-Pons RM,Carmen Recio M,Ríos JL

    更新日期:2000-11-01 00:00:00

  • Wogonoside displays anti-inflammatory effects through modulating inflammatory mediator expression using RAW264.7 cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The root of Scutellaria baicalensis Georgi, also called Huangqin in China, is an herbal-based nutraceutical which is usually used in Chinese medicated diet (CMD). As an abundant ingredient in Huangqin, wogonoside is a flavonoid glycoside. The present work investigated the anti-inflammator...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.04.025

    authors: Yang YZ,Tang YZ,Liu YH

    更新日期:2013-06-21 00:00:00

  • Intestinal anti-inflammatory effects of fuzi-ganjiang herb pair against DSS-induced ulcerative colitis in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Fuzi and ganjiang are widely used as traditional Chinese medicines (TCM) in China, Korea, Japan, and many other southeast Asian countries for treating ulcerative colitis (UC), emesis and heart failure for more than 1800 years. However, the underlying mechanism of fuzi, ganjiang and fuzi-g...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112951

    authors: Huang C,Dong J,Jin X,Ma H,Zhang D,Wang F,Cheng L,Feng Y,Xiong X,Jiang J,Hu L,Lei M,Wu B,Zhang G

    更新日期:2020-10-28 00:00:00

  • In vitro antibacterial activities of three plants used in traditional medicine in Sierra Leone.

    abstract::The antibacterial activities of the methanol and hot and cold aqueous extracts of the leaves of Aspilia africana, Ficus exasperata and Mareya micrantha were bioassayed against three Gram-negative and three Gram-positive bacterial species: Aerobacter aerogenes, Agrobacterium tumefaciens, Bacillus subtilis, Clostridium ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(90)90083-6

    authors: Macfoy CA,Cline EI

    更新日期:1990-03-01 00:00:00

  • Toxicological evaluation of acute and sub-chronic ingestion of hydroalcoholic extract of Solanum cernuum Vell. in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Solanum cernuum Vellozo is a Brazilian shrub or small tree, restricted to Southwest states of the country. It has been widely used for the treatment of many ailments. The pharmacological activity of the extract on gastric ulcer has been the major therapeutic target proposed by the populat...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2011.09.045

    authors: Almança CC,Saldanha SV,Sousa DR,Trivilin LO,Nunes LC,Porfírio LC,Marinho BG

    更新日期:2011-11-18 00:00:00