Preventive effect of Abelmoschus manihot (L.) Medik. on bone loss in the ovariectomised rats.

Abstract:

:Because the biggest culprit in pathogenesis of osteoporosis is oestrogen deficiency, hormone replacement therapy remained the mainstay for prevention. However most of postmenopausal women are more inclined to use natural alternative. We thus investigated the ability of Abelmoschus manihot, a herbal medicine to prevent bone loss in ovariectomised rats. Female Wistar rats were sham operated (SH: 8) or ovariectomised (OVX: 24). On day 0, OVX rats were randomly assigned to groups as follows: eight received 10% Abelmoschus manihot leaves in their diet, eight were given 15% Abelmoschus manihot leaves and eight were untreated (OVX). Compounds were mixed with a soy protein-free diet and given orally for 3 months. At necropsy, bone mineral density (BMD) in the femur and in its metaphyseal zone was lower in OVX than SH (p<0.05). This osteopenia was prevented by consumption of the highest dose of Abelmoschus manihot leaves. Bone mineral content (BMC) in the total femur and its metaphyseal and diaphyseal subregions was improved, as well (p<0.05). This could be explained by a trend towards decreased bone resorption. The lowest dose did not elicit any significant effect. In conclusion, Abelmoschus manihot consumption, at the dose of 15% in the diet, provided bone-sparing effects by improving both BMD and BMC.

journal_name

J Ethnopharmacol

authors

Puel C,Mathey J,Kati-Coulibaly S,Davicco MJ,Lebecque P,Chanteranne B,Horcajada MN,Coxam V

doi

10.1016/j.jep.2005.01.047

keywords:

subject

Has Abstract

pub_date

2005-05-13 00:00:00

pages

55-60

issue

1

eissn

0378-8741

issn

1872-7573

pii

S0378-8741(05)00124-8

journal_volume

99

pub_type

杂志文章
  • Hepatoprotective potential of Aloe barbadensis Mill. against carbon tetrachloride induced hepatotoxicity.

    abstract::Aloe barbadensis Mill. Syn. Aloe vera Tourn. ex Linn.(Liliaceae) has been used in variety of diseases in traditional Indian system of medicine in India and its use for hepatic ailments is also documented. In the present study an attempt has been made to validate its hepatoprotective activity. The shade dried aerial pa...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.01.008

    authors: Chandan BK,Saxena AK,Shukla S,Sharma N,Gupta DK,Suri KA,Suri J,Bhadauria M,Singh B

    更新日期:2007-05-22 00:00:00

  • [Ethnobotany of Euphorbiaceae of West Africa].

    abstract::The following ethnobotanical study is a compilation of medicinal Euphorbiaceae in West Africa (Senegal, Gambia, Guinea Bissau, Guinea, Sierra Leone, Liberia, Ivory Coast, Mali, Bourkina Faso, Ghana, Togo, Bénin, Niger, Nigeria), and includes 81 species distributed in 37 genera. It includes a reminder of the genera's p...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(86)90064-4

    authors: Stäuble N

    更新日期:1986-04-01 00:00:00

  • Antimicrobial activity of the methanolic extract, fractions and four flavonoids from the twigs of Dorstenia angusticornis Engl. (Moraceae).

    abstract::The methanolic extract (DAT), fractions (FRS) and four flavonoids, namely Gancaonin Q (1), Stipulin (2), Angusticornin B (3) and Bartericin A (4), isolated from the twigs of Dorstenia angusticornis (Moraceae), were tested for their in vitro antimicrobial activity. A total of 22 microbial cultures belonging to three Ca...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.03.008

    authors: Kuete V,Simo IK,Ngameni B,Bigoga JD,Watchueng J,Kapguep RN,Etoa FX,Tchaleu BN,Beng VP

    更新日期:2007-06-13 00:00:00

  • Inhibitory activity of Jatropha multifida latex on classical complement pathway activity in human serum mediated by a calcium-binding proanthocyanidin.

    abstract::This study isolates and characterizes the anti-complement constituent(s) present in the latex of Jatropha multifida, in an attempt to explain the traditional application of the latex in the treatment of infected wounds. Guided by the inhibition of classical pathway (CP) complement activity in human serum, a polymer wa...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(89)90080-9

    authors: Kosasi S,Hart LA,van Dijk H,Labadie RP

    更新日期:1989-11-01 00:00:00

  • Effect of some Indian herbs on macrophage functions in ochratoxin A treated mice.

    abstract::The effect of Indian herbs namely, Asparagus racemosus, Tinospora cordifolia, Withania somnifera and Picrorhiza kurrooa on the functions of macrophages obtained from mice treated with the carcinogen ochratoxin A (OTA) was investigated. The chemotactic activity of murine macrophages was significantly decreased by 17 we...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(97)00072-x

    authors: Dhuley JN

    更新日期:1997-09-01 00:00:00

  • Cytotoxicity and modes of action of five Cameroonian medicinal plants against multi-factorial drug resistance of tumor cells.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Beilschmiedia acuta Kosterm, Clausena anisata (Willd) Hook, Fagara tessmannii Engl., Newbouldia laevis Seem., and Polyscias fulva (Hiern) Harms. are medicinal plants used in Cameroonian traditional medicine in the treatment of various types of cancers. The present study aims at investigat...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2014.02.025

    authors: Kuete V,Tankeo SB,Saeed ME,Wiench B,Tane P,Efferth T

    更新日期:2014-04-11 00:00:00

  • Effects of dichloromethane and butanol fractions of Gochnatia polymorpha floccosa in maternal reproductive outcome, embryo-fetal development and DNA integrity in mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Gochnatia polymorpha ssp. floccosa (Asteraceae) also known as ''Cambará'' is used as medicinal plant in Brazil to treat infections and inflammation. Previous studies showed that its ethanolic extract could be bioprospecting of a new anti-inflammatory phytotherapy for use during pregnancy....

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.02.042

    authors: Pessatto LR,Auharek SA,Gonçalves CA,de David N,Monreal AC,Kassuya CA,Antoniolli-Silva AC,Stefanello MÉ,Oliveira RJ

    更新日期:2017-03-22 00:00:00

  • A RNA-seq approach for exploring the protective effect of ginkgolide B on glutamate-induced astrocytes injury.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:There is substantial experimental evidence to support the view that Ginkgo biloba L. (Ginkgoaceae), a traditional Chinese medicine known to treating stroke, has a protective effect on the central nervous system and significantly improves the cognitive dysfunction caused by disease, includ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2021.113807

    authors: Wang J,Zhuang L,Ding Y,Wang Z,Xiao W,Zhu J

    更新日期:2021-01-12 00:00:00

  • Evaluation of spasmolytic activity of clausmarin-A. a novel coumarin from Clausena pentaphylla (Roxb.) DC.

    abstract::Crude ethanolic (50%) extracts of five species of Clausena exhibited varying degrees of spasmolytic activity on the isolated guinea-pig ileum preparation. The aerial parts of Clausena pentaphylla had maximum activity. Its active principle clausmarin-A, a novel coumarin terpenoid, was evaluated in detail for spasmolyti...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(82)90001-0

    authors: Patnaik GK,Dhawan BN

    更新日期:1982-09-01 00:00:00

  • Chemical composition and antifungal activity of essential oils of seven Moroccan Labiatae against Botrytis cinerea Pers: Fr.

    abstract::Essential oils of seven Moroccan Labiatae were chemically analysed by GC-MS and evaluated for their in vitro antifungal activity against Botrytis cinerea. Among them, Origanum compactum and Thymus glandulosus greatly inhibited the growth of the mycelium. The inhibition of Botrytis cinerea was 100% for both oils at 100...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(03)00275-7

    authors: Bouchra C,Achouri M,Idrissi Hassani LM,Hmamouchi M

    更新日期:2003-11-01 00:00:00

  • Pharmacological evaluation of Alstonia scholaris: anti-tussive, anti-asthmatic and expectorant activities.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Alstonia scholaris (Apocynaceae) was documented as an effective herb for the treatment of chronic respiratory diseases in "dai" ethnopharmacy historically, and its leaf crude extract, used for releasing tracheitis and cold symptom, was approved to be a commercial formulation by State Food...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2010.03.029

    authors: Shang JH,Cai XH,Zhao YL,Feng T,Luo XD

    更新日期:2010-06-16 00:00:00

  • Rosmarinus officinalis L. hydroalcoholic extract, similar to fluoxetine, reverses depressive-like behavior without altering learning deficit in olfactory bulbectomized mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Rosemary, Rosmarinus officinalis L., has several therapeutic applications in folk medicine for the treatment of a wide range of diseases, including depression. AIM OF THE STUDY:To evaluate the ability of Rosmarinus officinalis hydroalcoholic extract (ROHE), as compared to the positive cont...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.06.017

    authors: Machado DG,Cunha MP,Neis VB,Balen GO,Colla AR,Grando J,Brocardo PS,Bettio LE,Dalmarco JB,Rial D,Prediger RD,Pizzolatti MG,Rodrigues AL

    更新日期:2012-08-30 00:00:00

  • Immunomodulatory functions of extracts from the Chinese medicinal fungus Cordyceps cicadae.

    abstract::The effects of Cordyceps cicadae extracted fractions on human mononuclear cells (HMNC) proliferation were determined by tritiated thymidine uptake. The results indicated that aqueous methanol (50%) extracts of C. cicadae ascocarps portion (CC-1-2) enhanced HMNC proliferation activated with phytohemagglutinin (PHA) wit...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(02)00212-x

    authors: Weng SC,Chou CJ,Lin LC,Tsai WJ,Kuo YC

    更新日期:2002-11-01 00:00:00

  • Alibertia edulis (L.C. Rich.) A.C. Rich - A potent diuretic arising from Brazilian indigenous species.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Although Alibertia edulis (L.C. Rich.) A.C. Rich decoction is used in Brazilian folk medicine due to its possible antihypertensive effect, this species has never been critically investigated as a hypotensive drug. So, the aim of this study was to evaluate the possible hypotensive and anti...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2016.12.024

    authors: de Santana Aquino DF,Signor Tirloni CA,Tolouei Menegati SE,Lima Cardoso CA,Heredia Vieira SC,Carmo Vieira MD,Simonet AM,Macías FA,Gasparotto A Junior

    更新日期:2017-01-20 00:00:00

  • Synergistic interaction between the Ligusticum chuanxiong constituent butylidenephthalide and the nitric oxide donor sodium nitroprusside in relaxing rat isolated aorta.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ligusticum chuanxiong Hort. (Umbelliferae), a traditional Chinese medicinal herb, is often prescribed together with nitric oxide donors for treating coronary heart diseases such as angina in China; however, studies concerning their pharmacological interaction are scarce. AIM OF THE STUDY...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2009.01.002

    authors: Chan SS,Jones RL,Lin G

    更新日期:2009-03-18 00:00:00

  • From ethnobotanical uses of Strychnos henningsii to antiinflammatories, analgesics and antispasmodics.

    abstract::Strychnos henningsii Gilg is used in African traditional medicine for the treatment of various ailments, including rheumatism, gastrointestinal complaints and snake bites. Different preliminary pharmacological experiments are described. The results show that some of the reported folk medicinal applications of S. henni...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/0378-8741(91)90045-f

    authors: Tits M,Damas J,Quetin-Leclercq J,Angenot L

    更新日期:1991-09-01 00:00:00

  • An ethnobotanical study of plants used to treat liver diseases in the Maritime region of Togo.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:In Togo, many persons still rely on plants for healing, however very little is known about the medicinal practices of the indigenous people. The present study aimed to document the medicinal plant utilization for the management of liver diseases in the Maritime region of the country. MET...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.12.051

    authors: Kpodar MS,Karou SD,Katawa G,Anani K,Gbekley HE,Adjrah Y,Tchacondo T,Batawila K,Simpore J

    更新日期:2016-04-02 00:00:00

  • Drug-likeness prediction of chemical constituents isolated from Chinese materia medica Ciwujia.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Ciwujia (CWJ), one of the most commonly used Chinese materia medicas (CMMs), is derived from the roots, rhizomes, and stems of Acanthopanax senticosus harms (AS). CWJ has been used for the treatment of various central nervous system (CNS) and peripheral system diseases. Drug-likeness pred...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.01.002

    authors: Zhang SN,Li XZ,Yang XY

    更新日期:2017-02-23 00:00:00

  • Improvement in mitochondrial function underlies the effects of ANNAO tablets on attenuating cerebral ischemia-reperfusion injuries.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:ANNAO tablets derive from Chinese classical prescriptions of Angong Niuhuang Pills with modified compositions, which have been singly or combined used for stoke associated neurological disorders. However the underlying mechanism is not yet well-defined, the present study investigated its ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.112212

    authors: Zhang Y,Cao M,Wu Y,Wang J,Zheng J,Liu N,Yang N,Liu Y

    更新日期:2020-01-10 00:00:00

  • Panax quinquefolium saponins inhibited immune maturation of human monocyte-derived dendritic cells via blocking nuclear factor-κB pathway.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Panax quinquefolium saponins (PQS), a water-soluble antioxidant extracted from a natural herb, radix panacis quinquefolii (American Ginseng), has yielded encouraging results in the treatment of atherosclerotic diseases. However, the underlying mechanisms remain unclear. Here, we tested th...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.03.029

    authors: Liu H,Shi D,Wang W,Zhang C,Fu M,Ge J

    更新日期:2012-06-14 00:00:00

  • Efficacy of inhaled Lavandula angustifolia Mill. Essential oil on sleep quality, quality of life and metabolic control in patients with diabetes mellitus type II and insomnia.

    abstract:ETHNOPHARMACOLOGIC RELEVANCE:Lavandula angustifolia Mill (lavender) odor was traditionally used as sleep enhancer. Previous studies have shown interaction between insomnia, quality of life and control of diabetes mellitus (DM). Insomnia is suggested to increase the risk of depression and decrease the quality of life in...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2020.112560

    authors: Nasiri Lari Z,Hajimonfarednejad M,Riasatian M,Abolhassanzadeh Z,Iraji A,Vojoud M,Heydari M,Shams M

    更新日期:2020-04-06 00:00:00

  • Essential oil from Fructus Alpinia zerumbet (fruit of Alpinia zerumbet (Pers.) Burtt.et Smith) protected against aortic endothelial cell injury and inflammation in vitro and in vivo.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Fructus Alpinia zerumbet (FAZ), a dry and ripe fruit of Alpinia zerumbet (Pers.) Burtt. et Smith, is widely used as a spice to treat cardiovascular diseases in clinic as a miao folk medicine in Guizhou Province of China. Essential oil extracted from FAZ (EOFAZ) is the key bioactive ingred...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2019.03.011

    authors: Ji YP,Shi TY,Zhang YY,Lin D,Linghu KG,Xu YN,Tao L,Lu Q,Shen XC

    更新日期:2019-06-12 00:00:00

  • Effect of an aqueous extract of Cucurbita ficifolia Bouché on the glutathione redox cycle in mice with STZ-induced diabetes.

    abstract:ETHNOPHARMACOLOGICAL IMPORTANCE:Cucurbita ficifolia is used in Mexican traditional medicine as an anti-diabetic and anti-inflammatory agent and its actions can be mediated by antioxidant mechanisms. Disturbance in the homeostasis of glutathione has been implicated in the etiology and progression of diabetes mellitus an...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2012.08.036

    authors: Díaz-Flores M,Angeles-Mejia S,Baiza-Gutman LA,Medina-Navarro R,Hernández-Saavedra D,Ortega-Camarillo C,Roman-Ramos R,Cruz M,Alarcon-Aguilar FJ

    更新日期:2012-10-31 00:00:00

  • Knowledge on plants used traditionally in the treatment of tuberculosis in Uganda.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Tuberculosis (TB) is one of the leading causes of morbidity and mortality globally. The disease is especially important because of increasing drug resistant strains and co infection with human immune virus (HIV) and acquired immune disease syndrome (AIDS). Because of this there is need to...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2013.12.020

    authors: Bunalema L,Obakiro S,Tabuti JR,Waako P

    更新日期:2014-02-03 00:00:00

  • Possible mechanisms of action of Caesalpinia pyramidalis against ethanol-induced gastric damage.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Caesalpinia pyramidalis Tul. (Fabaceae), known as "catingueira", is an endemic tree of the Northeast region of Brazil. This plant, mainly inner bark and flowers, has been used in traditional medicine to treat gastritis, heartburn, indigestion, stomachache, dysenteries, and diarrheas. MAT...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2015.03.054

    authors: Diniz PB,Ribeiro AR,Estevam CS,Bani CC,Thomazzi SM

    更新日期:2015-06-20 00:00:00

  • Various uses of the castor oil plant (Ricinus communis L.). A review.

    abstract::The ancient and modern medicinal uses of the castor bean plant, Ricinus communis L. (Euphorbiaceae), in about fifty countries worldwide, has been surveyed. The different medicinal uses are grouped separately in relation to their pharmacological action, whether real or presumed, within the various medical specialties. ...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/0378-8741(82)90038-1

    authors: Scarpa A,Guerci A

    更新日期:1982-03-01 00:00:00

  • Guarana (Paullinia cupana): toxic behavioral effects in laboratory animals and antioxidants activity in vitro.

    abstract::The effects on toxic and behavioral levels of guarana (Paullinia cupana) were assessed in rats and mice subsequent to acute and chronic administrations and were compared to those produced by Ginseng (Panax ginseng). Experimental parameters included tests for antioxidant capacity in vitro and measured in vivo, toxicolo...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/s0378-8741(97)00141-4

    authors: Mattei R,Dias RF,Espínola EB,Carlini EA,Barros SB

    更新日期:1998-03-01 00:00:00

  • Evaluation of Senegalese plants used in malaria treatment: focus on Chrozophora senegalensis.

    abstract::An ethnobotanical study was conducted in the Dakar area of Senegal to investigate the species used in the treatment of malaria. Seven plants are principally used: Cissampelos mucronata, Maytenus senegalensis, Terminalia macroptera, Bidens engleri, Ceratotheca sesamoides, Chrozophora senegalensis and Mitracarpus scaber...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2007.10.033

    authors: Benoit-Vical F,Soh PN,Saléry M,Harguem L,Poupat C,Nongonierma R

    更新日期:2008-02-28 00:00:00

  • Xuefu Zhuyu decoction ameliorates obesity, hepatic steatosis, neuroinflammation, amyloid deposition and cognition impairment in metabolically stressed APPswe/PS1dE9 mice.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:Metabolic syndrome and vascular dysfunction was suggested to be the risk factors for Alzheimer's disease (AD). Xuefu Zhuyu decoction (XZD) is a traditional Chinese medicine used to treat metabolic syndrome and cardiac-cerebral vascular disease. The effects of XZD on ameliorating metabolic...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章

    doi:10.1016/j.jep.2017.07.036

    authors: Yeh CW,Liu HK,Lin LC,Liou KT,Huang YC,Lin CH,Tzeng TT,Shie FS,Tsay HJ,Shiao YJ

    更新日期:2017-09-14 00:00:00

  • Phytochemical constituents, distributions and traditional usages of Arnebia euchroma: a review.

    abstract:ETHNOPHARMACOLOGICAL RELEVANCE:The present study has indicated phytochemical composition, distribution and ethno-medicinal uses of Arnebia euchroma (Royle) I.M. Johnst, which is commonly known as "Ratanjot" in the Indian subcontinent. It has widely been used in the traditional systems of the Unani, Ayurvedic and Chines...

    journal_title:Journal of ethnopharmacology

    pub_type: 杂志文章,评审

    doi:10.1016/j.jep.2021.113896

    authors: Kumar A,Shashni S,Kumar P,Pant D,Singh A,Verma RK

    更新日期:2021-01-29 00:00:00