Abstract：
:The 2-deoxyglucose (2-DG) autoradiographic technique was used to map functional activity in the central auditory system of the mongolian gerbil, throughout the period of functional onset. Uptake of 2-DG during exposure to 105 dB SPL wide band noise (WBN) was compared to silence in adults and in neonates at 12, 14, 16 and 18 days after birth (DAB). At 12 DAB, WBN exposure increased 2-DG uptake relative to silence only in the ventral cochlear nucleus. At 14 DAB, 2-DG uptake increased during WBN in the entire cochlear nuclear complex, superior olivary complex, and ventral nucleus of the lateral lemniscus. These stimulus-evoked increases in 2-DG uptake were at adult levels. However, little or no stimulus-evoked increase was seen in higher auditory nuclei at 14 DAB. By 16 DAB, 2-DG uptake also increased during WBN exposure in the dorsal nucleus of the lateral lemniscus, inferior colliculus and medial geniculate nucleus. By 18 DAB, WBN exposure produced increases in 2-DG uptake of medullary and pontine auditory nuclei which exceeded those seen in adults. At higher levels of the pathway, increases were comparable to those seen in adults. WBN-induced increases in 2-DG uptake observed in the cochlear nuclear and superior olivary complexes of neonates were comparable in all regions at all ages, even at 12 DAB. However, the 2-DG uptake increases observed at 16 and 18 DAB were appreciably greater in those regions of the inferior colliculus and medial geniculate nucleus which respond to high frequencies.
journal_name
Exp Brain Resjournal_title
Experimental brain researchauthors
Ryan AF,Woolf NK,Sharp FRdoi
10.1007/BF00239360subject
Has Abstractpub_date
1982-01-01 00:00:00pages
428-36issue
3eissn
0014-4819issn
1432-1106journal_volume
47pub_type
杂志文章abstract：:We investigated the post-train effects of repetitive transcranial magnetic stimulation (rTMS) on motor evoked potential (MEP) size and cortical silent period (SP) duration. rTMS was delivered over the primary motor cortex in trains of 5, 10, 20, 40 and 60 stimuli in normal subjects at rest and in trains of 5, 10 and 2...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0638-9
更新日期：2007-02-01 00:00:00
abstract：:Chronic loss of vestibular function modifies the role of neck afferents in human perception of self-motion. We characterized this change by comparing the self-motion perception of patients with chronic vestibular loss (Ps) to that of normal subjects (Ns). Stimuli consisted of sinusoidal horizontal rotations (0.025-0.4...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00227147
更新日期：1993-01-01 00:00:00
abstract：:We previously showed that saccades tend to overshoot briefly flashed targets that were manually displaced in the dark (Ren et al. 2006). However it was not clear if the overshoot originated from a sensory error in measuring hand displacement or from a premotor error in saccade programming, because gaze and hand positi...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0981-5
更新日期：2007-09-01 00:00:00
abstract：:Lengthening and shortening contractions are the fundamental patterns of muscle activation underlying various movements. It is still unknown whether or not there is a muscle-specific difference in such a fundamental pattern of muscle activation. The purpose of this study was, therefore, to investigate whether or not th...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-006-0743-9
更新日期：2007-04-01 00:00:00
abstract：:Previous studies in our laboratory examining pointing and reach-to-grasp movements of Parkinson's disease patients (PDPs) have found that PDPs exhibit specific deficits in movement coordination and in the sensorimotor transformations required to accurately guide movements. We have identified a particular difficulty in...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-005-0080-4
更新日期：2006-01-01 00:00:00
abstract：:The tuberomammillary nucleus (TM) located in the posterior part of the hypothalamus is the main source of neuronal histamine in the central nervous system. Recent work from our laboratories has indicated an involvement of the TM region in neuronal plasticity and reinforcement processes. In the present study, we invest...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210050301
更新日期：1998-02-01 00:00:00
abstract：:Tetanus toxin (TeT) is an exotoxin and has a capacity for neuronal binding and internalization. In the present study, we compared changes in the immunoreactivities and protein levels of interleukin (IL-) 2 as a pro-inflammatory cytokine and IL-4 as an anti-inflammatory cytokine in the hippocampus proper (HP) and denta...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3257-7
更新日期：2012-11-01 00:00:00
abstract：:(1) The responses of CA1 pyramidal cells to short glutamate pulses (10-50 ms) delivered at sensitive spots in the apical dendrites have been analysed by intracellular recording. (2) The glutamate pulses elicited stable depolarizing responses in a dose- and frequency-dependent manner. (3) When a single action potential...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00228178
更新日期：1992-01-01 00:00:00
abstract：:The effects of learning on strategy selection in the context of action imitation have been investigated in two experiments conducted with healthy individuals. It was predicted that, once learnt, meaningless actions are processed by the cognitive system as meaningful and this new representational status might influence...
journal_title：Experimental brain research
pub_type： 临床试验,杂志文章
doi：10.1007/s00221-006-0395-9
更新日期：2006-08-01 00:00:00
abstract：:In a recent study (Whitwell et al. in Exp Brain Res 185:111-119, 2008), we showed that the visuomotor system is "cognitively impenetrable" to the extent that explicit predictive knowledge of the availability of visual feedback on an upcoming trial fails to optimize grasping. The results suggested that the effects of t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1737-1
更新日期：2009-04-01 00:00:00
abstract：:Quantitative analysis of dendritic orientation in rapid Golgi sections of the lateral geniculate nucleus of Old World monkeys was performed with the help of a computer-microscope and a tree-analysing program. The orientation of intermediate and terminal dendritic segments of parvocellular and magnocellular multipolar ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00236293
更新日期：1984-01-01 00:00:00
abstract：:Electrophysiological methods were employed to study the axonal properties of the neurons of anterior olfactory nucleus (AON), transition zone (TZ), and rostral prepyriform cortex (RPPC) and their projections towards the ipsilateral and contralateral olfactory bulb (IOB, COB) in the rat. Of 91 antidromically driven cel...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00237113
更新日期：1980-01-01 00:00:00
abstract：:This study was designed to determine how visual feedback mediates error corrections during reaching. We used visuomotor rotations to dissociate a cursor, representing finger position, from the actual finger location. We then extinguished cursor feedback at different distances from the start location to determine wheth...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-009-1749-x
更新日期：2009-05-01 00:00:00
abstract：:Excess thyroid hormone at an early stage of development produces marked neurochemical and morphological alterations in the rat hippocampal formation. In order to better understand the functional significance of these changes, we tested adult rats treated neonatally with triiodothyronine (T3), and their control litter ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00231740
更新日期：1991-01-01 00:00:00
abstract：:In many daily situations, balance control is associated with a cognitive activity such as reading or a simple calculation. The objective of this study was to investigate the relationship between these two specific human activities, especially the influence of visual cues and support surface stability on body sway duri...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-014-3913-1
更新日期：2014-07-01 00:00:00
abstract：:The projection from the nucleus prepositus hypoglossi (PH) to the superior colliculus (SC) has been proposed to provide a feedback control of collicular saccadic activities. The present study aimed to identify the functional properties of PH neurones projecting to the SC relative to eye movement parameters. Preposito-...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00229141
更新日期：1996-08-01 00:00:00
abstract：:The eyeblink reflex is one of the most extensively studied behaviors in mammals. The active downward force that causes lid closure is controlled by the orbicularis oculi (OO) muscle. To augment our studies on the neurophysiology and plasticity of the rat eyeblink circuit, here we present the first anatomical paper to ...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/pl00005729
更新日期：1997-08-01 00:00:00
abstract：:When dividing attention between the left and right sides of physical space, most individuals pay slightly more attention to the left side. This phenomenon, known as pseudoneglect, may also occur for the left and right sides of mental representations of stimuli. Representational pseudoneglect has been shown for the rec...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4735-0
更新日期：2016-11-01 00:00:00
abstract：:When a target moves to a new location during a rapid aiming movement, the hand follows it, even when the participant intends not to. Pisella et al. (Nat Neurosci 3:729-736, 2000) claim that the posterior parietal cortex, in the dorsal visual stream, is responsible for this 'automatic pilot'. Here we study the limits o...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-007-0935-y
更新日期：2007-08-01 00:00:00
abstract：:Unitary discharges of the lateral geniculate nucleus (LGN) were analyzed in anesthetized and paralyzed rats after inactivation of visual cortical areas (VC) by cryoblockade or by depositing a cotton wick soaked in KCl (3 M). The receptive fields were mapped prior to and following the interruption of the cortico-genicu...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00238152
更新日期：1984-01-01 00:00:00
abstract：:To understand spatiotemporally coordinated activity in neural networks and interaction between different areas or layers in brain tissue, simultaneous multisite recording is a prerequisite. For in vitro studies pursuing these goals, substrate integrated, planar microelectrode arrays (MEAs) have been developed to monit...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-001-0932-5
更新日期：2002-01-01 00:00:00
abstract：:Parkinson's disease (PD) is a multifactorial disease with a complex etiology that results from genetic risk factors, environmental exposures and most likely a combination of both. Rodent models of parkinsonism aim to reproduce key pathogenic features of the syndrome including movement disorder induced by the progressi...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s00221-006-0461-3
更新日期：2006-08-01 00:00:00
abstract：:Recent morphological observations have suggested neurotransmitter specific degeneration of amongst others, the serotonergic system in the aged rat brain. However, morphological studies can only give a static picture of the events that take place over a period of several months. In the present study we used an experime...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230689
更新日期：1989-01-01 00:00:00
abstract：:This study investigated the modulation of somatosensory evoked potentials (SEPs) during precisely controlled force generation and force relaxation in a visuomotor tracking task. Subjects were instructed to track a target line with a line that represented their own force generated by grip movement with the right hand a...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-012-3082-z
更新日期：2012-06-01 00:00:00
abstract：:We studied characteristics of digit action and their co-variation patterns across trials (prehension synergies) during static holding of an object while the external torque could change slowly and smoothly. The subjects held in the air an instrumented handle with an attachment that allowed a smooth change in the exter...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2799-4
更新日期：2011-09-01 00:00:00
abstract：:Limitations in visual working memory (VWM) have been extensively studied in psychophysical tasks, but not well understood in terms of how these memory limits translate to performance in more natural domains. For example, in reaching to grasp an object based on a spatial memory representation, overshooting the intended...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-016-4553-4
更新日期：2016-06-01 00:00:00
abstract：:Previous experiments have suggested that the analysis of visual images could be a gravity-dependent process. We investigated this hypothesis using a mental rotation paradigm with pictures of three-dimensional objects during a 26-day orbital flight aboard the Soviet MIR station. The analysis of cosmonauts' response tim...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/BF00230478
更新日期：1993-01-01 00:00:00
abstract：:A compensatory stepping response (CSR) is a common strategy to restore dynamic stability in response to a postural disturbance. Currently, few studies have investigated the CSR to laterally directed disturbances delivered to subjects during quiet standing. The purpose of this study was to characterize the CSR of young...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s00221-011-2854-1
更新日期：2011-10-01 00:00:00
abstract：:In the present article a number of comparative lesion studies in two inbred strains of mice (C57BL/6 and DBA/2) with different levels of radial maze performance are reviewed. The effects of lesions in several brain areas on maze learning were investigated, thus revealing strain differences in the neural circuitry subs...
journal_title：Experimental brain research
pub_type： 杂志文章,评审
doi：10.1007/s002210050542
更新日期：1998-11-01 00:00:00
abstract：:We investigated anatomical and physiological properties of the projection from the pretectal nuclear complex (PNC) to the ipsilateral lateral posterior-pulvinar complex in the cat. After Phaseolus vulgaris leucoagglutinin injections into the PNC, the majority (70%) of anterogradely labeled terminals was localized in t...
journal_title：Experimental brain research
pub_type： 杂志文章
doi：10.1007/s002210100738
更新日期：2001-06-01 00:00:00
