Abstract:
:About 1900, modern food selection and processing caused widespread epidemics of the B vitamin deficiency diseases of beriberi and pellagra which, for genetic reasons, often expressed as different diseases ranging from bowel and heart disease to dermatoses and psychoses. But the B vitamins merely help convert essential fatty acids (EFA) into the prostaglandin (PG) tissue regulators and it now turns out that, through hydrogenation, milling and selection of w3-poor southern foods, we have also been systematically depleting, by as much as 90%, a newly discovered trace Nordic EFA (w3) of special importance to primates and sole precursor of the PG3(4) series, even as a concurrent fiber deficiency increases body demand for EFA. Since substrate EFA is processed by many B vitamin catalysts, an EFA deficiency will mimic a panhypovitaminosis B, i.e., a mixture of substrate beriberi and substrate pellagra resembling vitamin beriberi and pellagra but exhibiting as even more diverse endemic disease. This would constitute a second stage of the Modern Malnutrition and explain why some workers now hold the dominant diseases of modernized societies to be new, nutritionally based, pellagraform yet lipid-related and to range, once again, from heart disease to psychosis. It is an assumption that our dominant diseases are unrelated to each other or are merely revealed by out diagnostic acumen and therapeutic success; and that hydrogenating millions of tons of food oils annually, to destroy the rancidity producing w30EFA, is safe for primates. Extensive beriberiform disease is reported here in 32 typical cases taken from medical practice which responds strikingly to linseed oil supplements (60% w3-EFA) in confirmation of identical results in Capuchins.
journal_name
Med Hypothesesjournal_title
Medical hypothesesauthors
Rudin DOdoi
10.1016/0306-9877(82)90088-3subject
Has Abstractpub_date
1982-01-01 00:00:00pages
17-47issue
1eissn
0306-9877issn
1532-2777pii
0306-9877(82)90088-3journal_volume
8pub_type
杂志文章abstract::Elevated levels of aluminium (Al), strontium (Sr), barium (Ba), iron (Fe), manganese (Mn) cations - combined with deficiencies of magnesium (Mg)/calcium (Ca) - have been observed in the foodchains that traditionally support the Chamorro populations affected by high incidence clusters of Alzheimer (AD), Parkinson-like ...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2004.04.029
更新日期:2004-01-01 00:00:00
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journal_title:Medical hypotheses
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2020-11-01 00:00:00
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journal_title:Medical hypotheses
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pub_type: 杂志文章
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pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2007.01.029
更新日期:2007-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 历史文章,杂志文章
doi:10.1016/j.mehy.2009.12.012
更新日期:2010-05-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(97)90315-7
更新日期:1997-03-01 00:00:00
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pub_type: 杂志文章,评审
doi:10.1016/j.mehy.2009.12.025
更新日期:2010-08-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2020.110073
更新日期:2020-10-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.1999.0920
更新日期:2000-04-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/s0306-9877(96)90036-5
更新日期:1996-07-01 00:00:00
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pub_type: 杂志文章
doi:10.1016/j.mehy.2014.10.013
更新日期:2014-12-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2018.08.025
更新日期:2018-11-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(90)90025-a
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journal_title:Medical hypotheses
pub_type: 杂志文章
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:1997-08-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2006-01-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2017.03.029
更新日期:2017-06-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1054/mehy.2001.1298
更新日期:2001-07-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
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更新日期:2012-05-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2012.12.041
更新日期:2013-04-01 00:00:00
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journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/j.mehy.2005.02.028
更新日期:2005-01-01 00:00:00
abstract::A comparison is made of the x-ray induced thyroid adenocarcinoma in the rat by the in-vitro, in-vivo method of Clifton et al. with previous data of Doniach on in-vivo irradiation in whole animals. The Clifton data consists of only one point at 500 rad. I have assumed that the probability of transformation per viable c...
journal_title:Medical hypotheses
pub_type: 杂志文章
doi:10.1016/0306-9877(84)90070-7
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