Abstract：
:Guinea-pig mitogenic factor(s) were found capable of stimulating both normal T and B cells. Preliminary physicochemical characterization could not dissociate the mitogenic factors for respective cell populations. Furthermore, both immune T and B cells could produce mitogenic factors upon stimulation with antigen in contrast to some other lymphokines which are known to be produced only by immune T cells. While T-cell-derived mitogenic factor was active on both allogenic T and B cells, it was only mitogenic to syngeneic B cells and not to syngeneic T cells. B-cell-derived factor, on the other hand, could stimulate both T and B cells either of syngeneic or allogeneic origin.
journal_name
Immunologyjournal_title
Immunologyauthors
Bergenstock RW,Cohen S,Yoshida Tsubject
Has Abstractpub_date
1981-02-01 00:00:00pages
321-7issue
2eissn
0019-2805issn
1365-2567journal_volume
42pub_type
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