Clinical experience of zinc supplementation during intravenous nutrition in Crohn's disease: value of serum and urine zinc measurements.

abstract：BACKGROUND AND AIMS:A low dietary folate intake can cause genomic DNA hypomethylation and may increase the risk of colorectal neoplasia. The hypothesis that folic acid supplementation increases DNA methylation in leucocytes and colorectal mucosa was tested in 31 patients with histologically confirmed colorectal adenoma...

journal_title：Gut

authors： Pufulete M,Al-Ghnaniem R,Khushal A,Appleby P,Harris N,Gout S,Emery PW,Sanders TA

更新日期：2005-05-01 00:00:00

abstract：:Seventy six patients with dysphagia caused by malignant tumours of the oesophagus or gastric cardia have been treated using the Neodymium Yttrium Aluminium Garnet (NdYag) laser. The laser was set to deliver 80-100 watts of power for 0.5-1 second pulses. To obtain improvement, patients on average needed four treatment ...

journal_title：Gut

authors： Krasner N,Barr H,Skidmore C,Morris AI

更新日期：1987-07-01 00:00:00

abstract：OBJECTIVE:To develop gene expression profiles that characterise KRAS-, BRAF- or PIK3CA-activated- tumours, and to explore whether these profiles might be helpful in predicting the response to the epidermal growth factor receptor (EGFR) pathway inhibitors better than mutation status alone. DESIGN:Fresh frozen tumour sa...

journal_title：Gut

authors： Tian S,Simon I,Moreno V,Roepman P,Tabernero J,Snel M,van't Veer L,Salazar R,Bernards R,Capella G

更新日期：2013-04-01 00:00:00

abstract：BACKGROUND:Caroli's disease is a rare congenital disorder characterised by cystic dilatation of the intrahepatic bile ducts and an increased risk of cholangiocellular carcinoma. The cause is unknown, but occasional familial clustering suggests that some cases are inherited, in particular when occurring in association w...

journal_title：Gut

authors： Parada LA,Hallén M,Hägerstrand I,Tranberg KG,Johansson B

更新日期：1999-11-01 00:00:00

abstract：:THE SMOOTH MUSCLE SPHINCTERIC ACTIVITY OF THE ANUS IN CATS IS BASED ON TWO DISTINCT MECHANISMS: a typical anal component, characterized by anal slow pressure waves not related to spike potentials in the internal anal sphincter, and an intestinal-like pressure component related to spiking activity in the internal sphin...

journal_title：Gut

authors： Kerremans R,Penninckx F

更新日期：1970-08-01 00:00:00

abstract：BACKGROUND:Previous experimental studies have suggested many possible anti-cancer mechanisms for green tea, but epidemiological evidence for the effect of green tea consumption on gastric cancer risk is conflicting. OBJECTIVE:To examine the association between green tea consumption and gastric cancer. METHODS:We anal...

journal_title：Gut

authors： Inoue M,Sasazuki S,Wakai K,Suzuki T,Matsuo K,Shimazu T,Tsuji I,Tanaka K,Mizoue T,Nagata C,Tamakoshi A,Sawada N,Tsugane S,Research Group for the Development and Evaluation of Cancer Prevention Strategies in Japan.

更新日期：2009-10-01 00:00:00

abstract：:Colorectal cancer is the fourth commonest form of cancer in men with 678 000 estimated new cases per year worldwide, representing 8.9% of all new cancers. The disease is most frequent in Occidental countries and particularly so in North America, Australia, New Zealand, and parts of Europe. Prospects for colorectal can...

journal_title：Gut

authors： Langman M,Boyle P

更新日期：1998-10-01 00:00:00

abstract：BACKGROUND:Bovine immunoglobulin concentrate (BIC)-Clostridium difficile is prepared from the colostrum of cows immunised against C difficile toxins and contains high concentrations of neutralising IgG antitoxin. AIMS:To determine the proportion of BIC-C difficile which survives passage through the human stomach and s...

journal_title：Gut

authors： Warny M,Fatimi A,Bostwick EF,Laine DC,Lebel F,LaMont JT,Pothoulakis C,Kelly CP

更新日期：1999-02-01 00:00:00

abstract：:To test whether there is a difference in the expression of interleukin 8 (IL8) between Crohn's disease and ulcerative colitis and to determine the main site of its synthesis this study analysed IL8 in mucosal biopsy specimens of patients with Crohn's disease and ulcerative colitis by enzyme linked immunosorbent assay ...

journal_title：Gut

authors： Daig R,Andus T,Aschenbrenner E,Falk W,Schölmerich J,Gross V

更新日期：1996-02-01 00:00:00

abstract：:We report two patients with periampullary cysts associated with recurrent attacks of acute pancreatitis. In both patients the diagnosis was made preoperatively by upper gastrointestinal endoscopy and ERCP, which was also useful in determining the relationship of the cysts to the biliary and pancreatic ductal systems. ...

journal_title：Gut

authors： Kalvaria I,Bornman PC,Girdwood AH,Marks IN

更新日期：1987-03-01 00:00:00

abstract：:In a prospective survey positive antimitochondrial antibodies have been detected in 69/4200 (1.64%) of all sera submitted to a routine immunology laboratory. Of the 69, only nine patients had uniquivocal primary biliary cirrhosis, six others had chronic active hepatitis, 10 had abnormal liver function tests without ev...

journal_title：Gut

authors： Triger DR,Charlton CA,Ward AM

更新日期：1982-10-01 00:00:00

abstract：:The thoracic duct was cannulated in six patients who were actively bleeding from varices and had not responded to conservative treatment but draining lymph from the thoracic duct did not control bleeding in five patients. There was no drop in intrasplenic pulp pressure following this procedure when recorded in three o...

journal_title：Gut

authors： Datta DV,Singh SA,Patra BS,Saini VK,Chhuttani PN

更新日期：1971-01-01 00:00:00

abstract：:The enteric nervous system of several species, including the mouse, rat, guinea pig and humans, contains cannabinoid CB1 receptors that depress gastrointestinal motility, mainly by inhibiting ongoing contractile transmitter release. Signs of this depressant effect are, in the whole organism, delayed gastric emptying a...

journal_title：Gut

authors： Pertwee RG

更新日期：2001-06-01 00:00:00

abstract：:A technique for obtaining needle aspiration cytology specimens from upper gastrointestinal lesions at endoscopy is described. The validity of the technique was initially confirmed by applying it to resected gastric carcinomas. Thirty seven endoscopically visualised lesions were then sampled by forceps biopsy, brush an...

journal_title：Gut

authors： Ingoldby CJ,Mason MK,Hall RI

更新日期：1987-09-01 00:00:00

abstract：BACKGROUND:Recent profile studies of microRNA (miRNA) expression have documented a deregulation of miRNA (miR-124) in hepatocellular carcinoma (HCC). OBJECTIVE:To determine the status of miR-124 expression and its underlying mechanisms in the pathogenesis of HCC. METHODS:The expression levels of miR-124 were first ex...

journal_title：Gut

authors： Zheng F,Liao YJ,Cai MY,Liu YH,Liu TH,Chen SP,Bian XW,Guan XY,Lin MC,Zeng YX,Kung HF,Xie D

更新日期：2012-02-01 00:00:00

abstract：OBJECTIVES:Despite being proposed 4 years ago, there has been no independent validation study of the Rome IV criteria for IBS. We assessed their performance for the diagnosis of IBS in secondary care and compared them with the previous iteration, the Rome III criteria. DESIGN:We collected complete symptom data from co...

journal_title：Gut

authors： Black CJ,Craig O,Gracie DJ,Ford AC

更新日期：2020-09-24 00:00:00

abstract：:Visceral hypersensitivity has been recognised as a characteristic of patients with irritable bowel syndrome (IBS). It may be involved in the pathogenesis of abdominal pain/discomfort, and seems to result from the sensitisation of nerve afferent pathways originating from the gastrointestinal tract. From a clinical poin...

journal_title：Gut

authors： Delvaux M

更新日期：2002-07-01 00:00:00

abstract：BACKGROUND AND AIM:Hepatic stellate cells (HSCs) are key participants in liver fibrosis development. 1,25(OH)(2)D(3), the active form of vitamin D, has antiproliferative properties and antifibrotic potential, as well as a role in extracellular matrix and matrix metalloproteinase (MMP) regulation in renal and lung fibro...

journal_title：Gut

authors： Abramovitch S,Dahan-Bachar L,Sharvit E,Weisman Y,Ben Tov A,Brazowski E,Reif S

更新日期：2011-12-01 00:00:00

abstract：OBJECTIVE:The risk of GI bleeding (GIB) in aspirin users after Helicobacter pylori (HP) eradication remains poorly defined. We characterised the incidences and temporal trends of hospitalisations for all GIB in aspirin users after HP eradication therapy. DESIGN:Based on a territory-wide health database, we identified ...

journal_title：Gut

authors： Guo CG,Cheung KS,Zhang F,Chan EW,Chen L,Wong IC,Leung WK

更新日期：2020-03-01 00:00:00

abstract：:The role of the proximal and distal stomach in the emptying of solids and liquids from the stomach remains unclear. We have used a dual isotope technique to quantify proximal and distal stomach emptying of a solid (100 g of 99mTc labelled liver/ground beef) liquid (either 200 ml of normal saline (eight subjects) or 25...

journal_title：Gut

authors： Collins PJ,Houghton LA,Read NW,Horowitz M,Chatterton BE,Heddle R,Dent J

更新日期：1991-06-01 00:00:00

abstract：BACKGROUND:Melanoma inhibitory activity 2 (MIA2) is a novel gene of the MIA gene family. The selective expression of MIA2 in hepatocytes is controlled by hepatocyte nuclear factor (HNF) 1 binding sites in the MIA2 promotor. In contrast, in most hepatocellular carcinomas (HCC) MIA2 expression is down-regulated or lost. ...

journal_title：Gut

authors： Hellerbrand C,Amann T,Schlegel J,Wild P,Bataille F,Spruss T,Hartmann A,Bosserhoff AK

更新日期：2008-02-01 00:00:00

abstract：:Removal of the right lobe of the liver which was occupied largely by metastases, together with resection of ileal primary tumours, brought about complete remission of symptoms and signs in a 43-year-old man with a six-year history of the carcinoid syndrome. Investigations should be orientated toward surgery. When prac...

journal_title：Gut

authors： Zeegen R,Rothwell-Jackson R,Sandler M

更新日期：1969-08-01 00:00:00

abstract：:The effect of sulphasalazine and olsalazine on jejunal and ileal water and electrolyte absorption was investigated in normal subjects by a steady state intestinal perfusion of a physiological glucose bicarbonate electrolyte solution in the absence and presence of increasing concentrations of each drug. (Olsalazine 0.2...

journal_title：Gut

authors： Raimundo AH,Patil DH,Frost PG,Silk DB

更新日期：1991-03-01 00:00:00

abstract：:A series of experiments has been performed in healthy male volunteers to investigate the disposition of orally administered disodium azodisalicylate, a potentially useful drug for the treatment of ulcerative colitis. The drug was given by mouth in doses of up to 2 g a day for six weeks and there were no adverse effect...

journal_title：Gut

authors： Willoughby CP,Aronson JK,Agback H,Bodin NO,Truelove SC

更新日期：1982-12-01 00:00:00

abstract：BACKGROUND AND AIMS:CD8 T cells are central to the control of hepatitis C virus (HCV) although the key features of a successful CD8 T cell response remain to be defined. In a cohort of Irish women infected by a single source, a strong association between viral clearance and the human lecucocyte (HLA)-A*03 allele has be...

journal_title：Gut

authors： Fitzmaurice K,Petrovic D,Ramamurthy N,Simmons R,Merani S,Gaudieri S,Sims S,Dempsey E,Freitas E,Lea S,McKiernan S,Norris S,Long A,Kelleher D,Klenerman P

更新日期：2011-11-01 00:00:00

abstract：:This experimental study was undertaken to follow the influence of phenobarbital on bile chemistry and gallstone formation. Phenobarbital (400 mg/kg/day) was administered to golden hamsters receiving a diet known to induce cholesterol gallstones. After a 28-day period none of the control animals had gallstones whereas ...

journal_title：Gut

authors： Lagarriga J,Bouchier IA

更新日期：1973-12-01 00:00:00

abstract：:Epithelial cells shed from the intestinal villus in starved rats were trapped in mucus which the goblet cells were stimulated to secrete; the number of trapped cells per villus was counted in whole mounts of fixed Feulgen-stained specimens from three sites in the small intestine. Increase in the interval between stimu...

journal_title：Gut

authors： Clarke RM

更新日期：1970-12-01 00:00:00

abstract：UNLABELLED:Data on the natural history of elderly-onset inflammatory bowel disease (IBD) are scarce. METHODS:In a French population-based cohort we identified 841 IBD patients >60 years of age at diagnosis from 1988 to 2006, including 367 Crohn's disease (CD) and 472 ulcerative colitis (UC). RESULTS:Median age at dia...

journal_title：Gut

authors： Charpentier C,Salleron J,Savoye G,Fumery M,Merle V,Laberenne JE,Vasseur F,Dupas JL,Cortot A,Dauchet L,Peyrin-Biroulet L,Lerebours E,Colombel JF,Gower-Rousseau C

更新日期：2014-03-01 00:00:00

abstract：:Although changes in T lymphocyte subset distribution in the peripheral blood of patients infected with human immunodeficiency virus (HIV) are well defined it is not known whether these changes reflect changes in lymphoid compartments clearly involved in HIV related disease like the intestinal mucosa. This study analys...

journal_title：Gut

authors： Schneider T,Jahn HU,Schmidt W,Riecken EO,Zeitz M,Ullrich R

更新日期：1995-10-01 00:00:00

abstract：:Possible mechanisms by which liver antigen presenting cells (APC) may facilitate tolerance induction are discussed. Tolerance may be facilitated by a distinctive combination of factors, linked to the unique anatomical and microenvironmental features of the liver. ...

journal_title：Gut

authors： Lau AH,de Creus A,Lu L,Thomson AW

更新日期：2003-08-01 00:00:00