Binding of aflatoxin B1, G1 and M to plasma albumin.

Abstract:

:The aflatoxins B1, G1 and their metabolites exist in the systemic blood as protein conjugate. This conjugation is specific to plasma albumin and proceeds enzymatically by liver and kidney cells. The aflatoxin-albumin conjugate is permanent and the conjugation is an irreversible one. This may interpret the acute liver damage of animal ingested a single dose of aflatoxin (3,4). The existence of bound aflatoxin-albumin in the systematic blood could be considered as one factor of low excretions of aflatoxins and their metabolites in urine (5,6,7).

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Nassar AY,Megalla SE,El-Fattah HM,Hafez AH,El-Deap TS

doi

10.1007/BF00636179

subject

Has Abstract

pub_date

1982-07-23 00:00:00

pages

35-8

issue

1

eissn

0301-486X

issn

1573-0832

journal_volume

79

pub_type

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