Development toxicity of fumonisin in Syrian hamsters.

Abstract:

:The effects of fumonisin on development of Syrian hamster fetuses were studied using fumonisin B1 and B2 extracted from Fusarium moniliforme corn-culture and purified fumonisin B1. A significant increase in litters with fetal deaths occurred with the high doses of purified (18 mg FB1/kg) and culture-extracted (18 mg FB1 plus 4.5 mg FB2) fumonisin. It is concluded that prenatal exposure to fumonisin on days 8 and 9 of gestation is detrimental to fetal hamster survivability but does not induce clinical maternal intoxication at these doses. Equivalent doses of fumonisin B1, whether from culture-extract or pure solution produced similar results.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Floss JL,Casteel SW,Johnson GC,Rottinghaus GE,Krause GF

doi

10.1007/BF01104276

subject

Has Abstract

pub_date

1994-10-01 00:00:00

pages

33-8

issue

1

eissn

0301-486X

issn

1573-0832

journal_volume

128

pub_type

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