Abstract：
:The development of intraperitoneal paracoccidioidomycosis was studied in groups of female and male rats: a) Under normal conditions (intacts), b) After castration and c) After castration but submitted to a treatment with, respectively, testosterone and estradiol. The criterion of susceptibility to infection was based on: 1) Spontaneous mortality of the animals and 2) Number of metastatic pulmonary lesions. The results showed that: the unique deaths and the more severe pulmonary lesions were found among the intact females, representing the animals most susceptible to the infection in these experiments; the intact females showed more numerous lesions than the castrated; the intact males had less lesions than the castrated, and than those castrated which were treated with estradiol.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Kerr IB,Schaeffer GV,Miranda DSdoi
10.1007/BF00436446subject
Has Abstractpub_date
1984-12-30 00:00:00pages
149-54issue
2-3eissn
0301-486Xissn
1573-0832journal_volume
88pub_type
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