Abstract:
:An intracellular beta-hemolysin capable of lysing human, sheep and cow erythrocytes but not cells from some other animals was isolated from the cell walls of the three developmental cell-forms of Nocardia asteroides and characterised. The spherical cell-forms contained the highest amounts of the hemolysin (100 h.u./mg protein) and the least LD50 for mice suggesting that this may be the cell-form most pathogenic to susceptible animals. The hemolysin has the properties of a protein, was pH stable and sensitive to both catabolite repression and temperature. The activity of the hemolysin was enhanced by Ca++ and Na+ ions. The hemolysin was immunogenic in rabbits.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Emeruwa ACdoi
10.1007/BF00436319subject
Has Abstractpub_date
1986-07-01 00:00:00pages
29-35issue
1eissn
0301-486Xissn
1573-0832journal_volume
95pub_type
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