Isolation and some properties of beta-hemolysin produced by Nocardia asteroides.

Abstract:

:An intracellular beta-hemolysin capable of lysing human, sheep and cow erythrocytes but not cells from some other animals was isolated from the cell walls of the three developmental cell-forms of Nocardia asteroides and characterised. The spherical cell-forms contained the highest amounts of the hemolysin (100 h.u./mg protein) and the least LD50 for mice suggesting that this may be the cell-form most pathogenic to susceptible animals. The hemolysin has the properties of a protein, was pH stable and sensitive to both catabolite repression and temperature. The activity of the hemolysin was enhanced by Ca++ and Na+ ions. The hemolysin was immunogenic in rabbits.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Emeruwa AC

doi

10.1007/BF00436319

subject

Has Abstract

pub_date

1986-07-01 00:00:00

pages

29-35

issue

1

eissn

0301-486X

issn

1573-0832

journal_volume

95

pub_type

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