Development of amphotericin B liposomes bearing antibody specific to Candida albicans.

Abstract:

:Liposomes expressing external antibody specific for Candida albicans and encapsulating amphotericin B were developed and characterized in this study. Antibody was first modified by the covalent attachment of palmitic acid residues. Liposomes were produced by reverse-phase evaporation and modified antibody was incorporated into these liposomes via the hydrophobic interaction between the palmitic acid and the phospholipids composing the liposomes. The liposomes were characterized as to the amount of amphotericin B by spectroscopy and for the presence of antibody by protein analysis and secondary immunolabeling by fluorescent and electron microscopic methods. Immunogold labeling showed that the antibody was being expressed externally on the liposomes in the electron microscopic studies and the specificity of these liposomes for C. albicans was observed by secondary immunofluorescence.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Hospenthal DR,Rogers AL,Mills GL

doi

10.1007/BF00455667

subject

Has Abstract

pub_date

1988-01-01 00:00:00

pages

37-45

issue

1

eissn

0301-486X

issn

1573-0832

journal_volume

101

pub_type

杂志文章
  • Prevalence of superficial mycoses in the Aosta Valley region of Italy from 1984 to 1989.

    abstract::This report represents the results of the culture tests for fungi carried out in the Aosta Valley region of Italy from 1984 to 1989. The pathological material consisted of cutaneous scales, hair and nails. It was possible to identify 91.8% of the isolates: out of these, 36.1% were dermatophytes, 21% were Aspergillus s...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00436829

    authors: Dal Tio R,Lunardi M

    更新日期:1991-12-01 00:00:00

  • High detection rates of cryptococcal antigen in pulmonary cryptococcosis by Eiken latex agglutination test with pronase pretreatment.

    abstract::Two different kits for the detection of serum cryptococcal antigen in patients with pulmonary cryptococcosis were evaluated. The Eiken test (the Eiken Co., Tokyo), which uses pronase for pretreatment of serum, was compared with the Crypto-LA test (International Biological Laboratories, Cranbury, NJ), which did not use...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF01365083

    authors: Kohno S,Yasuoka A,Koga H,Kaku M,Maesaki S,Tanaka K,Mitsutake K,Matsuda H,Hara K

    更新日期:1993-08-01 00:00:00

  • Susceptibility of clinical isolates of yeasts to anti-fungal agents.

    abstract::The antimicrobial activity of amphotericin B, 5-fluorocytosine, nystatin, clotrimazole and miconazole were compared in vitro against 244 strains of yeasts that had been isolated from clinical specimens. The yeasts used in this study included 20 species of Candida, Cryptococcus, Saccharomyces Geotrichum, Rhodotorula, T...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00437125

    authors: Hussain Qadri SM,Flournoy DJ,Qadri SG,Ramirez EG

    更新日期:1986-09-01 00:00:00

  • Mycotic keratitis caused by Curvularia lunata var. aeria.

    abstract::A mycotic keratitis case which was caused by Curvularia lunata var. aeria in a patient with an injury in the eye is described. The diagnosis was based on the mycologic analysis of several samples taken from the ulcer of cornea. In vitro tests of the sensitivity of the isolated species to several antifungal drugs were ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00437007

    authors: Luque AG,Nanni R,de Bracalenti BJ

    更新日期:1986-01-01 00:00:00

  • Entomophthora ferdinandii (Zygomycetes: Entomophthorales) causing natural infections of Musca domestica (Diptera: Muscidae) in Argentina.

    abstract::The identity and activity of an entomopathogenic fungus belonging to the Entomophthora muscae species complex and infecting Musca domestica in poultry houses from La Plata, Argentina, is reported. Entomophthora caused natural infections between September 2001 and September 2003. Primary conidia of this fungus were on ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-005-0248-2

    authors: Lastra CC,Siri A,García JJ,Eilenberg J,Humber RA

    更新日期:2006-04-01 00:00:00

  • The effects of four mycotoxins on the mitogen stimulated proliferation of bovine peripheral blood mononuclear cells in vitro.

    abstract::The effects of four mycotoxins, T-2 toxin, deoxynivalenol (DON), ochratoxin A (OTA) and fumonisin B1 (FB1) on the response of bovine peripheral blood mononuclear cells (PBM) in vitro to the mitogens concanavalin A (Con A), phytohaemagglutinin A (PHA) and pokeweed mitogen (PWM) were assayed after 4 days' incubation usi...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1006971724678

    authors: Charoenpornsook K,Fitzpatrick JL,Smith JE

    更新日期:1998-01-01 00:00:00

  • Ecophysiological factors affecting growth, sporulation and survival of the biocontrol agent Penicillium oxalicum.

    abstract::The effect of temperature, pH, water potential and sources of nitrogen and carbon on the biocontrol agent Penicillium oxalicum were studied in vitro. The fungus is xerotolerant, mesophillic and has a wide pH tolerance. The parameters evaluated (germination, germ tube length, growth rate and sporulation) showed differe...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/A:1006898724724

    authors: Pascual S,Rico JR,De Cal A,Melgarejo P

    更新日期:1997-01-01 00:00:00

  • Expression of complement receptor type 1 (CR1) on erythrocytes of paracoccidiodomycosis patients.

    abstract::Complement receptor type 1 (CR1) is a membrane glycoprotein that acts as a receptor for the C3b, iC3b and C4b fragments of complement. In primates, one function of erythrocytes is to promote safe clearance of immunocomplexes (IC) from the circulation through CR1. Theoretically, in diseases characterized by high levels...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1013123721376

    authors: Teixeira JE,Martinez R,Câmara LM,Barbosa JE

    更新日期:2001-01-01 00:00:00

  • Parengyodontium album Isolated from Cutaneous Lesions of a Pacific White-Sided Dolphin (Lagenorhynchus obliquidens) During Treatment for Paracoccidioidomycosis Ceti.

    abstract::The prominence of seafood in Japan motivates close monitoring of its seas and marine lives for potentially pathogenic fungi. During the treatments of the male Pacific white-sided dolphin (Lagenorhynchus obliquidens) for paracoccidioidomycosis ceti (PCM-C), 5 white and floccose colonies showing identical genotype and m...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-020-00484-3

    authors: Kanegae H,Tomino N,Nakamura Y,Minakawa T,Yaguchi T,Izawa T,Sano A,Itano EN,Ueda K

    更新日期:2020-12-01 00:00:00

  • Pichia anomala (Candida pelliculosa) fungemia in a patient with sickle cell disease.

    abstract::This case report discusses a patient with sickle cell disease who presented with fungemia from Pichia anomala (teleomorph: Candida pelliculosa). The organism was identified as P. anomala by MALDI-TOF VITEK mass spectrometry and VITEK 2 yeast identification card. Pichia anomala should be considered in sickle cell patie...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-013-9677-5

    authors: Chan AW,Cartwright EJ,Reddy SC,Kraft CS,Wang YF

    更新日期:2013-10-01 00:00:00

  • Antifungal activities of four fatty acids against plant pathogenic fungi.

    abstract::The effect of the fatty acids linolenic acid, linoleic acid, erucic acid and oleic acid on the growth of the plant pathogenic fungi Rhizoctonia solani, Pythium ultimum, Pyrenophora avenae and Crinipellis perniciosa were examined in in vitro studies. Linolenic and linoleic acids exhibited activity against all of the fu...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/b:myco.0000012222.68156.2c

    authors: Walters D,Raynor L,Mitchell A,Walker R,Walker K

    更新日期:2004-01-01 00:00:00

  • Meningitis Caused by Rhodotorula mucilaginosa in HIV-Infected Patient: A Case Report and Review of the Literature.

    abstract::Rhodotorula species are increasingly being identified as a cause of fungal infection in the central nervous system, especially in patients with compromised immunity. The diagnosis could easily be missed due to low index of suspicion, as cryptococcus meningitis and cerebral toxoplasmosis are more common amongst immunoc...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-015-9879-0

    authors: Mohd Nor F,Tan LH,Na SL,Ng KP

    更新日期:2015-08-01 00:00:00

  • Challenges in the therapy of chromoblastomycosis.

    abstract::Chromoblastomycosis (CBM) is an implantation mycosis mainly occurring in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM require long-term therapy with systemic antifungals flanked by various physical treatment regimens. As in other neglected endemic mycoses, comparative c...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-013-9648-x

    authors: Queiroz-Telles F,Santos DW

    更新日期:2013-06-01 00:00:00

  • In vitro susceptibility of Brazilian Pythium insidiosum isolates to essential oils of some Lamiaceae family species.

    abstract::The present study aimed to evaluate the in vitro antimicrobial action of Origanum vulgare, Origanum majorana, Mentha piperita and Rosmarinus officinalis on Pythium insidiosum oomycete zoospores. The antimicrobial activity evaluation was performed by the broth microdilution method according to CSLI M38-A2 documentation...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-014-9841-6

    authors: Fonseca AO,Pereira DI,Jacob RG,Maia Filho FS,Oliveira DH,Maroneze BP,Valente JS,Osório LG,Botton SA,Meireles MC

    更新日期:2015-04-01 00:00:00

  • Epidemiological, Clinical and Outcome Aspects of Patients with Cryptococcosis Caused by Cryptococcus gattii from a Non-endemic Area of Brazil.

    abstract::Cryptococcosis by Cryptococcus gattii occurs mainly in immunocompetent hosts, however, during the last decades, a growing number of cases in immunocompromised individuals have been noticed around the world. This report presents epidemiological, clinical and outcome aspects of patients with cryptococcosis caused by thi...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-018-0304-3

    authors: Damasceno-Escoura AH,de Souza ML,de Oliveira Nunes F,Pardi TC,Gazotto FC,Florentino DH,Mora DJ,Silva-Vergara ML

    更新日期:2019-02-01 00:00:00

  • Temporal and dose-response features in swine fed corn screenings contaminated with fumonisin mycotoxins.

    abstract::Fumonisin B1 (FB1), a mycotoxin produced by Fusarium moniliforme and F. proliferatum, induces liver damage and pulmonary edema in swine. We examined the temporal and dose-response features of FB1 toxicosis in male weanling crossbred pigs fed nutritionally balanced diets, containing corn screenings naturally contaminat...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF01371170

    authors: Motelin GK,Haschek WM,Ness DK,Hall WF,Harlin KS,Schaeffer DJ,Beasley VR

    更新日期:1994-04-01 00:00:00

  • Susceptibility of the ant-cultivated fungus Leucoagaricus gongylophorus (Agaricales: Basidiomycota) towards microfungi.

    abstract::The aim of this study was to select virulent strains of microfungi against Leucoagaricus gongylophorus, a symbiotic fungus cultivated by leaf-cutting ants. The results from in vitro assays showed that microfungal strains had a variable and significant impact on the colony development of L. gongylophorus. Specifically,...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-006-0037-6

    authors: Silva A,Rodrigues A,Bacci M Jr,Pagnocca FC,Bueno OC

    更新日期:2006-08-01 00:00:00

  • Toxigenic saprophytic fungi in marine shellfish farming areas.

    abstract::Toxigenic saprophytic fungi were isolated from samples of shellfish, sediment and seawater obtained from marine shellfish farming areas. The 456 strains identified included 12 different genera, with a clear predominance (68%) of Penicillium, Aspergillus, Trichoderma and Cladosporium. To assess the risk of poisoning du...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/a:1007259810190

    authors: Sallenave-Namont C,Pouchus YF,Robiou du Pont T,Lassus P,Verbist JF

    更新日期:2000-01-01 00:00:00

  • Four new species of penicillium isolated from the air.

    abstract::Four new species of Penicillium Link ex Fries are described and illustrated. All of them but one have been isolated from the atmosphere in Madrid. Spain. They clearly differ from all species of the genus described so far and are, therefore, described and proposed as new taxa: Penicillium aurantio-flammiferum sp. nov.,...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00443048

    authors: Ramírez C,Martinez AT,Berenguer J

    更新日期:1980-08-29 00:00:00

  • Association of anurans with pathogenic fungi.

    abstract::In a study of 450 Amazonian anurans, we isolated yeasts and yeast-like fungi from 54 animals (Bufo granulosus, B. marinus, Dendrophrynyscus sp., Hyla geographica, H. lanciformes, Ololygon rubra, Adenomera hylaedactyla, Eleutherodactylus fenestratus, Leptodactylus fuscus, L. ocellatus, L. pentadactylus). The internal o...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00442657

    authors: Mok WY,Morato de Carvalho C

    更新日期:1985-10-01 00:00:00

  • Transformation of sterigmatocystin and O-methylsterigmatocystin by aflatoxigenic and nonaflatoxigenic field isolates of the Aspergillus flavus group.

    abstract::Transformation of sterigmatocystin and O-methylsterigmatocystin (two metabolic aflatoxin precursors) to aflatoxins by aflatoxigenic and nonaflatoxigenic field isolates of Aspergillus flavus was studied. The 24 nonaflatoxigenic isolates investigated failed to transform both precursors. Among the 8 aflatoxin-producing i...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/BF00436367

    authors: Pro MJ,Moreno MA,Suárez G

    更新日期:1991-11-01 00:00:00

  • Hendersonula toruloidea infection in man. Index cases in the non-endemic North American host, and a review of the literature.

    abstract::Hendersonula toruloidea (HT) is a dematiaceous fungus that is an endemic human pathogen in tropical and subtropical countries. Infection with this fungus is often clinically indistinguishable from Trichophyton rubrum or other dermatophytoses. However, because HT will not grow on standard cycloheximide containing funga...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/BF00437252

    authors: Frankel DH,Rippon JW

    更新日期:1989-03-01 00:00:00

  • Oral Candida Mannan Concentrations Correlate with Symptoms/Signs of Ill Health and the Immune Status.

    abstract:BACKGROUND:A relationship has been proposed between increases in oral Candida concentrations and host immunity. Therefore, the present study was conducted to investigate the relationship between oral Candida mannan concentrations and symptoms/signs of ill health and the immune status and also to examine whether health/...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-020-00458-5

    authors: Hakoyama Y,Yamada SI,Nishimaki F,Hayashi K,Koizumi T,Kurita H

    更新日期:2020-08-01 00:00:00

  • Antifungal susceptibility profile of cryptic species of Aspergillus.

    abstract::The use of molecular tools has led to the description of new cryptic species among different Aspergillus species complexes. Their frequency in the clinical setting has been reported to be between 10 and 15%. The susceptibility to azoles and amphotericin B of many of these species is low, and some of them, such as Aspe...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-014-9775-z

    authors: Alastruey-Izquierdo A,Alcazar-Fuoli L,Cuenca-Estrella M

    更新日期:2014-12-01 00:00:00

  • Histopathology of canine sporotrichosis: a morphological study of 86 cases from Rio de Janeiro (2001-2007).

    abstract::The present study reports the histopathological findings of 86 skin lesions of dogs with sporotrichosis from Rio de Janeiro. Suppurative granulomatous inflammation was the predominant finding and was observed in 76 (88.37%) cases. Plasma cells surrounding the suppurative granulomas were detected in 68 (89.5%) cases an...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-009-9198-4

    authors: de Miranda LH,Quintella LP,dos Santos IB,Menezes RC,Figueiredo FB,Gremião ID,Okamoto T,de Oliveira RV,Pereira SA,Tortelly R,Schubach TM

    更新日期:2009-08-01 00:00:00

  • Lichtheimia Infection in a Lymphoma Patient: Case Report and a Brief Review of the Available Diagnostic Tools.

    abstract::We describe the case of a patient with a T-lymphoblastic lymphoma whose disseminated mucormycosis was diagnosed with delay, and we address the diagnostic and therapeutic decision-making process and review the diagnostic workup of patients with potential IFD. The diagnosis was delayed despite a suggestive radiological ...

    journal_title:Mycopathologia

    pub_type: 杂志文章,评审

    doi:10.1007/s11046-016-0010-y

    authors: Zimmerli S,Bialek R,Blau IW,Christe A,Lass-Flörl C,Presterl E

    更新日期:2016-08-01 00:00:00

  • Evaluation of the adherence of Candida species to urinary catheters.

    abstract::Catheter-associated urinary tract infections (CAUTIs) are the most common kind of nosocomial infection. Recent years have seen a significant increase in numbers of infections caused by yeasts of the genus Candida. The adherence of a microorganism to the host surface is a decisive factor in the success of colonization ...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1023/b:myco.0000003559.59676.f7

    authors: Tamura NK,Gasparetto A,Svidzinski TI

    更新日期:2003-01-01 00:00:00

  • Detection of (1, 3)-β-D-glucan in bronchoalveolar lavage and serum samples collected from immunocompromised hosts.

    abstract::The incidence of invasive fungal infections (IFI) has increased in recent years, especially among immunocompromised hosts (ICH). In 2003, the Fungitell(®) assay received FDA clearance for the presumptive diagnosis of IFI using serum and detects (1-3)-β-D-glucan, which is a major cell wall component of certain fungi (e...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-012-9579-y

    authors: Theel ES,Jespersen DJ,Iqbal S,Bestrom JE,Rollins LO,Misner LJ,Markley BJ,Mandrekar J,Baddour LM,Limper AH,Wengenack NL,Binnicker MJ

    更新日期:2013-02-01 00:00:00

  • In vitro determination of phagocytosis and intracellular killing of Aspergillus species by mononuclear phagocytes.

    abstract::We investigated phagocytosis and intracellular killing of clinical and environmental isolates of Aspergillus spp. by human monocyte-derived macrophages (MDMs). Serial pathogens such as Aspergillus fumigatus, Aspergillus flavus and Aspergillus terreus were examined with a microbiological assay. Phagocytosis for resting...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-007-9013-z

    authors: Perkhofer S,Speth C,Dierich MP,Lass-Flörl C

    更新日期:2007-06-01 00:00:00

  • Detection of satratoxin g and h in indoor air from a water-damaged building.

    abstract::The occurrence of Stachybotrys chartarum in indoor environments has been linked to adverse health effects as well as few cases of pulmonary haemorrhages in humans. Although the highly toxic secondary metabolites of this fungus, like satratoxin G and H, were frequently claimed with outbreaks of such diseases, these tox...

    journal_title:Mycopathologia

    pub_type: 杂志文章

    doi:10.1007/s11046-008-9126-z

    authors: Gottschalk C,Bauer J,Meyer K

    更新日期:2008-08-01 00:00:00