Abstract:
:The antimicrobial activity of amphotericin B, 5-fluorocytosine, nystatin, clotrimazole and miconazole were compared in vitro against 244 strains of yeasts that had been isolated from clinical specimens. The yeasts used in this study included 20 species of Candida, Cryptococcus, Saccharomyces Geotrichum, Rhodotorula, Torulopsis and Trichosporon. The majority of the strains (78%) had an MIC of less than or equal to 0.5 microgram/ml for amphotericin B, 81% an MIC of less than or equal to 1 microgram/ml for 5-fluorocytosine, 99% less than or equal to 8 micrograms/ml for nystatin, 91%, less than or equal to 8.0 micrograms/ml for clotrimazole and 98% had an MIC of less than or equal to 4.0 for miconazole. Of the anti-fungal agents tested, 5-fluorocytosine and nystatin were found to have the greatest antifungal activity.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Hussain Qadri SM,Flournoy DJ,Qadri SG,Ramirez EGdoi
10.1007/BF00437125subject
Has Abstractpub_date
1986-09-01 00:00:00pages
183-7issue
3eissn
0301-486Xissn
1573-0832journal_volume
95pub_type
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