Abstract:
:Pseudomonas aeruginosa is a ubiquitous and opportunistic bacterium that inhibits the growth of different microorganisms, including Gram-positive bacteria and fungi such as Candida spp. and Aspergillus fumigatus. In this study, we investigated the interaction between P. aeruginosa and Cryptococcus spp. We found that P. aeruginosa PA14 and, to a lesser extent, PAO1 significantly inhibited the growth of Cryptococcus spp. The inhibition of growth was observed on solid medium by the visualization of a zone of inhibition of yeast growth and in liquid culture by viable cell counting. Interestingly, such inhibition was only observed when P. aeruginosa and Cryptococcus were co-cultured. Minimal inhibition was observed when cell-cell contact was prevented using a separation membrane, suggesting that cell contact is required for inhibition. Using mutant strains of Pseudomonas quinoline signaling, we showed that P. aeruginosa inhibited the growth of Cryptococcus spp. by producing antifungal molecules pyocyanin, a redox-active phenazine, and 2-heptyl-3,4-dihydroxyquinoline (PQS), an extracellular quorum-sensing signal. Because both P. aeruginosa and Cryptococcus neoformans are commonly found in lung infections of immunocompromised patients, this study may have important implication for the interaction of these microbes in both an ecological and a clinical point of view.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Rella A,Yang MW,Gruber J,Montagna MT,Luberto C,Zhang YM,Del Poeta Mdoi
10.1007/s11046-011-9494-7subject
Has Abstractpub_date
2012-06-01 00:00:00pages
451-61issue
5-6eissn
0301-486Xissn
1573-0832journal_volume
173pub_type
杂志文章相关文献
MYCOPATHOLOGIA文献大全abstract::The isolation of a dysgonic variety of Microsporum canis from a large number of cats and kittens in a cattery is described. The normal variety of this fungus was isolated at the same time from the same animals. Dysgonic varieties are thought to be mutants of normal strains, but this isolation of both forms together su...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00578291
更新日期:1992-11-01 00:00:00
abstract::The yeast-like forms of six P. brasiliensis strains were characterized and compared using in vitro (growth curve determination) and in vivo (pathogenicity to sensitive inbred mice) criteria. Strains Pb 18 and Pb 265 which behaved similarly in vitro, showing low counts of fungi and long mean generation times, were resp...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00437630
更新日期:1985-12-01 00:00:00
abstract::The influx of inflammatory cells towards the peritoneal cavity in rats inoculated intraperitoneally with subcellular preparations of the fungus Paracoccidioides brasiliensis was studied. In addition to the dead fungus, also fractions F1 of the cell wall, which mainly consisted of polysaccharides and the lipid extract,...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00437324
更新日期:1987-01-01 00:00:00
abstract::During a period of 8 years 300 cases of dermatophytoses involving both hairy areas and the glabrous skin were found to be caused by M. canis. There was scalp involvement in 60%, including 8 infants and 27 adults; most of the adults presented Kerion-like lesions and presented various clinical aspects such as seborrhea ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00437169
更新日期:1986-08-01 00:00:00
abstract::Candida dubliniensis, yeast closely related to Candida albicans, is a new pathogen associated mainly with infections of immunocompromised hosts. In this study, we report the first isolation of three isolates of C. dubliniensis in Slovakia. The first selection of both C. albicans and C. dubliniensis from the other Cand...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-004-7399-4
更新日期:2005-04-01 00:00:00
abstract::An improved DNA-mediated transformation system for nematode-trapping fungus Arthrobotrys oligospora based on hygromycin B resistance was developed. The transformation frequency varied between 34 and 175 transformants per microg linearized DNA and 93% of the transformants were stable for drug resistance when tested 100...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-005-4334-2
更新日期:2005-06-01 00:00:00
abstract::The effects of fumonisin on development of Syrian hamster fetuses were studied using fumonisin B1 and B2 extracted from Fusarium moniliforme corn-culture and purified fumonisin B1. A significant increase in litters with fetal deaths occurred with the high doses of purified (18 mg FB1/kg) and culture-extracted (18 mg F...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF01104276
更新日期:1994-10-01 00:00:00
abstract::Availability of molecular methods, gene sequencing, and phylogenetic species recognition have led to rare fungi being recognized as opportunistic pathogens. Fungal keratitis and onychomycosis are fairly common mycoses in the tropics, especially among outdoor workers and enthusiasts. The frequently isolated etiological...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-018-0248-7
更新日期:2018-06-01 00:00:00
abstract::Onychomycosis are fungal infections affecting finger and toenails mainly caused by dermatophyte fungi and some Candida species. Low cure rates and frequent recurrence, development of a fungal resistance front to various antimicrobial agents topical and systemic, and an ineffective topical treatment make onychomycosis ...
journal_title:Mycopathologia
pub_type: 杂志文章,评审
doi:10.1007/s11046-015-9957-3
更新日期:2016-02-01 00:00:00
abstract::Most manifestations of candidiasis are associated with biofilm formation occurring on the surfaces of host tissues and medical devices. Candida albicans is the most frequently isolated causative pathogen of candidiasis, and the biofilms display significantly increased levels of resistance to the conventional antifunga...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-007-0097-2
更新日期:2007-03-01 00:00:00
abstract::Some epidemiologic, diagnostic and immunologic aspects of 93 (75 males and 18 women) cases of cryptococcosis (CRY) associated with AIDS, hospitalized in the Muñiz Hospital (MH) in Buenos Aires during 1994, were retrospectively studied. The median age (MA) of the patients under study was 28 years (17-49 y); 30 (17-49) ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/a:1006801502246
更新日期:1997-01-01 00:00:00
abstract::Cryptostegia madagascariensis is a plant native from Madagascar, belonging to the Apocynaceae that is invading the native vegetation in Northeast Brazil and threatening the unique riverine formations dominated by the carnauba palm. Individuals of C. madagascariensis cultivated in the campus of the Universidade Federal...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-008-9120-5
更新日期:2008-08-01 00:00:00
abstract::Catheter-associated urinary tract infections (CAUTIs) are the most common kind of nosocomial infection. Recent years have seen a significant increase in numbers of infections caused by yeasts of the genus Candida. The adherence of a microorganism to the host surface is a decisive factor in the success of colonization ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/b:myco.0000003559.59676.f7
更新日期:2003-01-01 00:00:00
abstract::A stainless steel paper-embedded biofilm reactor (PEBR) was developed for Candida spp. growth, permitting confluent distribution of nutrients by capillary diffusion through ordinary laboratory filter paper. Antibiogram disks were distributed along the filter paper rim, and the PEBR received 0.1 or 0.01 % crystal viole...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-015-9889-y
更新日期:2015-08-01 00:00:00
abstract::The habit of cigarette smoking is associated with higher oral candidal carriage and possible predisposition to oral candidosis. The effects of exposure to smoke on the virulence properties of oral yeasts remain obscure. Hence, we showed in vitro the effect of cigarette smoke condensate (CSC) on ten clinical isolates o...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-009-9217-5
更新日期:2009-11-01 00:00:00
abstract::Studies of Rhinosporidium seeberi have demonstrated that this organism has a complex life cycle in infected tissues. Its in vivo life cycle is initiated with the release of endospores into a host's tissues from its spherical sporangia. However, little is known about the mechanisms of sporangium formation and endospore...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/a:1007108910025
更新日期:1999-01-01 00:00:00
abstract::This case report discusses a patient with sickle cell disease who presented with fungemia from Pichia anomala (teleomorph: Candida pelliculosa). The organism was identified as P. anomala by MALDI-TOF VITEK mass spectrometry and VITEK 2 yeast identification card. Pichia anomala should be considered in sickle cell patie...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-013-9677-5
更新日期:2013-10-01 00:00:00
abstract::ALS1 and ALS3 encode cell-surface associated glycoproteins that are considered to be important for Candida albicans biofilm formation. The main goal of the present study was to monitor ALS1 and ALS3 gene expression during C. albicans biofilm formation (on silicone) under continuous flow conditions, using the Centers f...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-008-9148-6
更新日期:2009-01-01 00:00:00
abstract::The objectives of this study were to evaluate the fumonisin production by 16 F. verticillioides strains on corn cultures and the effect of quintozene and fludioxonil + metalaxyl-M fungicides on "in vitro" mycelial growth on agar. In addition, the effect of fludioxonil + metalaxyl-M on fumonisin production in defined l...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-010-9339-9
更新日期:2011-01-01 00:00:00
abstract::The mycoflora of nine varieties of grain sorghum was determined by plating serial dilutions of ground samples on rose bengal-streptomycin agar. Seventeen species of fungi representing 10 genera were identified. Curvularia, Penicillium, Mucor, and Aspergillus were dominant genera. Extracts of P. herquei were highly tox...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00439062
更新日期:1981-07-10 00:00:00
abstract::Phospholipases have only been detected in a few fungi and yeasts, in particular in Candida albicans. Secreted phospholipases are considered by some researchers to be a potential factor of virulence and pathogenicity in C. albicans. Twenty-three Cryptococcus neoformans strains were tested in order to observe phospholip...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00438916
更新日期:1996-01-01 00:00:00
abstract::We investigated phagocytosis and intracellular killing of clinical and environmental isolates of Aspergillus spp. by human monocyte-derived macrophages (MDMs). Serial pathogens such as Aspergillus fumigatus, Aspergillus flavus and Aspergillus terreus were examined with a microbiological assay. Phagocytosis for resting...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-007-9013-z
更新日期:2007-06-01 00:00:00
abstract::The pathogenicity of Trichosporon dermatis isolated from skin lesions of a patient has been examined in mice. Balb/c mice were treated with two intraperitoneal injections of 100 mg/kg cyclophosphamide on days 4 and 1 and one subcutaneous injection of 10 mg/kg dexamethasone on day 1 pre-inoculation, and then challenged...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-011-9442-6
更新日期:2011-11-01 00:00:00
abstract::A 4-year-old captive ringed seal (Pusa hispida) was treated with subcutaneous antibacterial injections for pus exuding wounds in the skin and associated blubber following a bite attack. Three months after the incident, the animal presented nystagmus and died the following day. At necropsy, there was a 25 × 18 × 25 mm ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-018-0268-3
更新日期:2018-12-01 00:00:00
abstract::Talaromyces marneffei, previously known as Penicillium marneffei, is the most important pathogenic thermally dimorphic fungus causing systemic mycosis in Southeast Asia. Traditionally, T. marneffei infection in human was mainly associated with acquired immunodeficiency syndrome caused by HIV infection. In recent years...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-017-0239-0
更新日期:2018-06-01 00:00:00
abstract::The occurrence of microfloral components on medicated and non-medicated swine and chicken feed pellets and crumbles, produced in a Manitoba feed mill between June 1991 and October 1992, was determined. Addition of medicates to feeds generally decreased bacterial incidence and increased that of Eurotium spp. fungi. The...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436571
更新日期:1996-01-01 00:00:00
abstract::Onychomycosis is a common condition that represents up to 50% of all nail problems and 30% of all cases of dermatophytoses. Trichophyton rubrum and Trichophyton interdigitale are the most common agents involved in this condition. In cases of recurrent post-treatment onychomycosis, strain fingerprinting could reveal wh...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-009-9261-1
更新日期:2010-04-01 00:00:00
abstract::Candida albicans strain B 311-10 with and without starvation was cultivated in the minimal synthetic medium of Shepherd et al., modified without biotin, amino acids, low glucose concentration and with decreasing amounts of (NH4)2SO4, to determine the optimal growth requirement for this strain. All the experiments were...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436116
更新日期:1991-03-01 00:00:00
abstract::A simple technique of epicutaneous inoculation of guinea-pigs making use of a polyethylene chamber stuck to the animal's skin with the Duracryl resin is described. In this way, inoculation with a defined number of fungal elements is made possible. ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00627875
更新日期:1976-10-22 00:00:00
abstract::Recently, we have reported serological cross-reactivity between paracoccidioidomycosis ceti and paracoccidioidomycosis, histoplasmosis, and coccidioidomycosis. However, data on the interaction of Arthrographis kalrae with the above pathogenic fungal infections are lacking. A. kalrae is a widely occurring ascomycetous ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-019-00348-5
更新日期:2019-06-01 00:00:00