Abstract：
:ALS1 and ALS3 encode cell-surface associated glycoproteins that are considered to be important for Candida albicans biofilm formation. The main goal of the present study was to monitor ALS1 and ALS3 gene expression during C. albicans biofilm formation (on silicone) under continuous flow conditions, using the Centers for Disease Control biofilm reactor (CDC reactor). For ALS1, we found few changes in gene expression until later stages of biofilm formation (72 and 96 h) when this gene appeared to be downregulated relative to the gene expression level in the start culture. We observed an induction of ALS3 gene expression in the initial stages of biofilm formation (0.5, 1, and 6 h), whereas at later stages, this gene was also downregulated relative to the gene expression level in the start culture. We also found that biofilms of an als3/als3 deletion mutant contained less filaments at several time points (1, 6, 24, and 48 h), although filamentation as such was not affected in this strain. Together, our data indicate an important role for ALS3 in the early phases of biofilm formation in the CDC reactor, probably related to adhesion of filaments, while the role of ALS1 is less clear.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Nailis H,Vandenbroucke R,Tilleman K,Deforce D,Nelis H,Coenye Tdoi
10.1007/s11046-008-9148-6subject
Has Abstractpub_date
2009-01-01 00:00:00pages
9-17issue
1eissn
0301-486Xissn
1573-0832journal_volume
167pub_type
杂志文章相关文献
MYCOPATHOLOGIA文献大全abstract：:Chromoblastomycosis (CBM) is an implantation mycosis mainly occurring in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM require long-term therapy with systemic antifungals flanked by various physical treatment regimens. As in other neglected endemic mycoses, comparative c...
journal_title：Mycopathologia
pub_type： 杂志文章,评审
doi：10.1007/s11046-013-9648-x
更新日期：2013-06-01 00:00:00
abstract：:The occurrence of microfloral components on medicated and non-medicated swine and chicken feed pellets and crumbles, produced in a Manitoba feed mill between June 1991 and October 1992, was determined. Addition of medicates to feeds generally decreased bacterial incidence and increased that of Eurotium spp. fungi. The...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00436571
更新日期：1996-01-01 00:00:00
abstract：:Fungal endophytes were isolated from Crataeva magna, a medicinal plant growing along the streams and rivers, constituting riparian vegetation in Karnataka, southern India. Fresh bark and twig pieces were used for the isolation using standard methods. Ninety-six endophytic fungal isolates were isolated from 800 bark an...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-004-5497-y
更新日期：2005-02-01 00:00:00
abstract：:It has been over a decade since Cryptococcus gattii was first recognized as the causative organism of an outbreak of cryptococcosis on Vancouver Island, British Columbia. A number of novel observations have been associated with the study of this emergent pathogen. A novel genotype of C. gattii, VGIIa was described as ...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-011-9475-x
更新日期：2012-06-01 00:00:00
abstract：:A mycotic keratitis case which was caused by Curvularia lunata var. aeria in a patient with an injury in the eye is described. The diagnosis was based on the mycologic analysis of several samples taken from the ulcer of cornea. In vitro tests of the sensitivity of the isolated species to several antifungal drugs were ...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00437007
更新日期：1986-01-01 00:00:00
abstract：:The aim of this study was to detect antibodies against Paracoccidioides brasiliensis in dogs seropositive and seronegative for leishmaniasis. Sera from 836 dogs (449 positive and 387 negative to leishmaniasis) were analysed by ELISA and the immunodiffusion test using gp43 and exoantigen, respectively. The analysis of ...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-006-0046-5
更新日期：2006-11-01 00:00:00
abstract：:This paper describes four new cases of lymphomas, two Hodgkin lymphomas and two non-Hodgkin lymphomas in patients with paracoccidioidomycosis. All had mycosis diagnosed before lymphomas with Paracoccidioides brasiliensis demonstrated in several lymph nodes, as seen in the disseminated form of the disease. When lymphom...
journal_title：Mycopathologia
pub_type： 杂志文章,评审
doi：10.1007/s11046-014-9851-4
更新日期：2015-04-01 00:00:00
abstract：:An improved DNA-mediated transformation system for nematode-trapping fungus Arthrobotrys oligospora based on hygromycin B resistance was developed. The transformation frequency varied between 34 and 175 transformants per microg linearized DNA and 93% of the transformants were stable for drug resistance when tested 100...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-005-4334-2
更新日期：2005-06-01 00:00:00
abstract：:The mycoflora of nine varieties of grain sorghum was determined by plating serial dilutions of ground samples on rose bengal-streptomycin agar. Seventeen species of fungi representing 10 genera were identified. Curvularia, Penicillium, Mucor, and Aspergillus were dominant genera. Extracts of P. herquei were highly tox...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00439062
更新日期：1981-07-10 00:00:00
abstract：:Paracoccidioidomycosis ceti is a cutaneous disease of cetaceans caused by uncultivated Paracoccidioides brasiliensis or Paracoccidioides spp. Serological cross-reactions between paracoccidioidomycosis ceti and paracoccidioidomycosis, paracoccidioidomycosis and histoplasmosis, and paracoccidioidomycosis and coccidioido...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-018-0295-0
更新日期：2018-10-01 00:00:00
abstract：:Histoplasmosis is an important systemic mycotic infection with a wide geographic distribution. Its occurrence has been mostly studied in the US (6) and in Central America (6), but very little is known about its distribution in Africa, where a specific variant exists. Skin test surveys in the Democratic Republic of Som...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00437292
更新日期：1987-05-01 00:00:00
abstract：:Essential oils extracted from Citrus reticulata and Cymbopogon citratus were tested in vitro against the toxigenic strain of Aspergillus flavus, isolated from the tuberous roots of Asparagus racemosus, used in preparation of herbal drugs. The essential oils completely inhibited the growth of A. flavus at 750 ppm and a...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-010-9311-8
更新日期：2010-09-01 00:00:00
abstract：:Four cases of Tinea Nigra by Exophiala werneckii, observed in Porto Alegre, RS, during the period 1981-1992 were related. A boy presented bilateral palmar lesions, one girl had plantar lesions and the remaining two girls had lesions on the palms. Three cases were autochthonous and the remaining patient was infected du...
journal_title：Mycopathologia
pub_type： 杂志文章,评审
doi：10.1007/BF01103769
更新日期：1994-06-01 00:00:00
abstract：:Mucormycosis is usually an invasive mycotic disease caused by fungi in the class mucormycetes. Here we report a case of cutaneous mucormycosis due to Lichtheimia ramosa in a 20-year-old female patient with burn injuries. She was admitted to the hospital with accidental flame burns covering 60 % total burn surface area...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-014-9805-x
更新日期：2014-10-01 00:00:00
abstract：:Recently, Trichosporon taxonomy has been reevaluated and new genera of the Trichosporonaceae family have been described. Here, 26 clinical isolates were submitted for identification via sequencing of the intergenic space 1 (IGS1) region, genotyping, and investigation of virulence factors. Antifungal susceptibility was...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-019-00407-x
更新日期：2020-04-01 00:00:00
abstract：:A case is presented in which yeastlike cells resembling the yeast phase of Paracoccidioides brasiliensis were observed by microscopic examination of a urine sample. A mold identified as Mucor circinelloides was isolated from the specimen. It was converted to the yeast form by cultivation on Sabouraud agar incubated in...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00437243
更新日期：1987-03-01 00:00:00
abstract：:A case of bursitis due to Prototheca wickerhamii is briefly reported. In histological sections the organism stained well with fungal stains, grey with silver methanamine and red with periodic acid Schiff reagent. This unicellular achlorophyllous alga was studied on common laboratory media. The characterization of the ...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00443013
更新日期：1981-01-30 00:00:00
abstract：:Malbranchea gypsea IMI 338,168 isolated from the soils of Keoladeo National Park, Bharatpur was studied for its ability to produce exocellular proteases on glucose-gelatin medium at pH 7; 28 degrees C. The fungus was observed to be a potent producer of such enzymes. Protease production was optimal at 15 days of incuba...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1023/a:1006968600404
更新日期：1998-01-01 00:00:00
abstract：:The effects of a modified natural porcine surfactant (Curosurf) on phagocytosis and killing of Cryptococcus neoformans by alveolar macrophages and on the production of superoxide anions were investigated in vitro. Attachment and ingestion were evaluated separately by a fluorescent quenching technique. The nitroblue te...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1023/a:1006948825384
更新日期：1998-01-01 00:00:00
abstract：:Clearance of cryptococcal polysaccharide (CP) from tissues and body fluids of nonimmune mice was studied. Mice were injected intravenously only with one mg of purified CP, and serum, urine and tissues were obtained from each animal at various intervals for a period of 84 days. Tissue extracts, serum and urine were tes...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00436580
更新日期：1982-04-23 00:00:00
abstract：:We report a familial infection caused by Microsporum canis. The first two patients were a 30-year-old female and her son, a 5-year-old boy, who came in contact with a pet dog at a farm house. The boy then suffered from hair loss for 3 months. There were circular and patchy alopecia with diffuse scaling on his scalp. M...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-013-9685-5
更新日期：2013-10-01 00:00:00
abstract：:Six water-soluble nystatin-polyvilnylpyrrolidone complexes with respective MW of 10 kDa (NC1), 25 kDa (NC2), 30 kDa (NC3), 40 kda (NC4), 90 kDa (NC5), 360 kDa (NC6) were synthesized. The activity of the complexes was compared with that of nystatin against growth and spore germination of Fusarium oxysporum f.sp. radici...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1023/a:1015252121285
更新日期：2002-01-01 00:00:00
abstract：:Rhodotorula species are increasingly being identified as a cause of fungal infection in the central nervous system, especially in patients with compromised immunity. The diagnosis could easily be missed due to low index of suspicion, as cryptococcus meningitis and cerebral toxoplasmosis are more common amongst immunoc...
journal_title：Mycopathologia
pub_type： 杂志文章,评审
doi：10.1007/s11046-015-9879-0
更新日期：2015-08-01 00:00:00
abstract：:A case of mycetoma caused by the black fungus Madurella grisea in northern Brazil is reported. The lesion was located on the patient's right foot without bone involvement. Clinical samples were collected by opening the fistules with a scalp and the grains removed for microbiological and histopathological analyses. Alt...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-004-2844-y
更新日期：2004-11-01 00:00:00
abstract：:Trichophyton benhamiae is a zoophilic dermatophyte mainly transmitted to humans from guinea pigs. This zoophilic species can also cause dermatophytosis as reported by human contact with other animals, such as rabbit, cat, and fox. Here, we report the tinea faciei and tinea corporis cases: a 12-year-old girl and her 53...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-020-00513-1
更新日期：2021-01-04 00:00:00
abstract：:The microorganisms capable of producing opportunist infections include the yeast-like organisms of the genus Candida, and the unicellular algae of the genus Prototheca, which share common features and can, therefore, lead to confusion. Their colonies are almost identical and they grow in the same culture media used ro...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1023/a:1006818606851
更新日期：1997-01-01 00:00:00
abstract：:Until the present decade, no studies had been conducted in Puerto Rico on the saprophytic distribution and variety of Cryptococcus neoformans. Samples (522) of pigeon droppings from 14 western towns were tested for the presence of C. neoformans. The yeast was recovered from 24.7% (129 isolates) of the samples, represe...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00443058
更新日期：1989-06-01 00:00:00
abstract：:Prototheca wickerhamii was isolated from the stool of a two month-old infant with diarrhea resistant to treatment. This is the first description from Spain of algae of the genus Prototheca isolated from human clinical specimens. The possible pathogenicity of the Prototheca in this case is discussed. ...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/BF00437407
更新日期：1983-01-01 00:00:00
abstract：:Outbreak of exogenous Fusarium endophthalmitis after cataract surgery was evaluated. Twenty patients developed postoperative endophthalmitis. In 19 eyes, pars plana vitrectomy (PPV) was performed, in 14 cases (74 %) with primary intraocular lens explantation. In one case, the PPV was not performed because of poor gene...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-013-9721-5
更新日期：2014-02-01 00:00:00
abstract：:Species of Aspergillus section Flavi were isolated and identified in maize samples collected from a wide geographical region in northeastern China. Aspergillus flavus was identified to be the primary species in the population (99%) becoming a potential source of aflatoxin contamination in the region. Isolated A. flavu...
journal_title：Mycopathologia
pub_type： 杂志文章
doi：10.1007/s11046-007-9029-4
更新日期：2007-08-01 00:00:00
