Abstract:
:Chromoblastomycosis (CBM) is an implantation mycosis mainly occurring in tropical and subtropical zones worldwide. If not diagnosed at early stages, patients with CBM require long-term therapy with systemic antifungals flanked by various physical treatment regimens. As in other neglected endemic mycoses, comparative clinical trials have not been performed for this disease; nowadays, therapy is mainly based on a few open trials and on expert opinions. Itraconazole, either as monotherapy or associated with other drugs, or with physical methods, is widely used. Recently, photodynamic therapy has been employed successfully in combination with antifungals in patients presenting with CBM. In the present paper, the most used therapeutic options against CBM are reviewed as well as the several factors that may have impact on the patient's outcome.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Queiroz-Telles F,Santos DWdoi
10.1007/s11046-013-9648-xsubject
Has Abstractpub_date
2013-06-01 00:00:00pages
477-88issue
5-6eissn
0301-486Xissn
1573-0832journal_volume
175pub_type
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