Abstract:
:Clearance of cryptococcal polysaccharide (CP) from tissues and body fluids of nonimmune mice was studied. Mice were injected intravenously only with one mg of purified CP, and serum, urine and tissues were obtained from each animal at various intervals for a period of 84 days. Tissue extracts, serum and urine were tested for CP content by enzyme-linked immunosorbent assay (ELISA) and latex agglutination. High concentrations of CP were detected by both assays one-half hour after injection in blood (serum), liver, spleen, kidney and lung (extracts). The duration of ELISA detectable CP was longest (70 days) in liver and spleen and shortest (14 days) in lung extract. By 14 days after injection, concentration of CP in the blood fell below that found in the liver and spleen. CP remained detectable (titers 32-64) after all other extracts became negative. These results indicate that CP is stored in tissues (binding mechanism and site unknown), and that the liver and spleen possess greater storage capacity than other tissues. Antibody (IgM) to CP appeared in low titer on the 14th day and thereafter.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Muchmore HG,Scott EN,Felton FG,Fromtling RAdoi
10.1007/BF00436580subject
Has Abstractpub_date
1982-04-23 00:00:00pages
41-5issue
1eissn
0301-486Xissn
1573-0832journal_volume
78pub_type
杂志文章相关文献
MYCOPATHOLOGIA文献大全abstract::Sesame seeds (Sesamum indicum L) from four different geographic locations in Sierra Leone were sampled for their mycoflora. Three toxigenic Aspergillus species: A. flavus Link ex Fries, A. ochraceus Wilhelm, and A. tamarii Kita were common to all samples. Penicillium citrinum Thom and two Fusarium sp. were found in sa...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436937
更新日期:1988-11-01 00:00:00
abstract::Dermatophytes are highly specialized pathogenic fungi that exclusively infect the stratum corneum, nails or hair, and it is evident that secreted proteolytic activity is important for their virulence. Endo- and exoproteases-secreted by dermatophytes are similar to those of species of the genus Aspergillus. However, in...
journal_title:Mycopathologia
pub_type: 杂志文章,评审
doi:10.1007/s11046-008-9105-4
更新日期:2008-11-01 00:00:00
abstract::The cellular immune response of 8 patients from the Brazilian Amazon region with chromoblastomycosis was analyzed. Primary immunological responses of patients were tested by contact sensitization to 2,4-dinitro-chlorobenzene (DNCB), or rejection of first set skin allografts. 2 of 8 patients were reactive to DNCB after...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00443936
更新日期:1992-08-01 00:00:00
abstract::Cutaneous lesions which can lead to false positive results have been observed in several rabbits used for the determination of the cutaneous irritation capacity of a product (ITA, PII). The responsible agent was Microsporum canis. A preventive treatment by an antifungal agent did not modify toxicological experimental ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436546
更新日期:1985-08-01 00:00:00
abstract::This is a comparative study to isolate the dermatophytes of tinea capitis using the cytobrush and comparing it versus the standard method. A prospective, observational, comparative trial of 178 probable cases of tinea capitis was conducted in two dermatological centers. Each patient underwent mycological tests that in...
journal_title:Mycopathologia
pub_type: 临床试验,杂志文章
doi:10.1007/s11046-007-9019-6
更新日期:2007-06-01 00:00:00
abstract::Owing to a lack of appropriate diagnostic and therapeutic approaches for mycotic keratitis, approximately one million cases of preventable corneal blindness are reported each year. The number of keratitis cases due to infection with Fusarium is increasing significantly worldwide, many of which are not treated adequate...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-018-0280-7
更新日期:2018-10-01 00:00:00
abstract::Four Norway rats (Rattus norvegicus) and one opossum (Didelphis virginiana) were surveyed for the presence of fungi. Eighteen different fungi were isolated from rat samples and six from the opossum, including Trichophyton mentagrophytes. Hair and skin scrapings from laboratory raised Norway rats, bedding and air from ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00625312
更新日期:1980-05-01 00:00:00
abstract::Chronic exposure to moniliformin results in the development of myocardial hypertrophy and degeneration. The cause of this hypertrophy is unknown. However, moniliformin-induced hypoxia or altered function of cardiac pyruvate dehydrogenase, rather than direct cardiostimulation have been proposed as potential mechanisms....
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00439122
更新日期:1996-01-01 00:00:00
abstract::We previously described an in vitro assay showing that neutrophils (PMNs) from patients with paracoccidioidomycosis (PARA) have a specific digestive deficiency against suspensions of live Paracoccidioides brasiliensis. We now report that this defect is equally detectable against autoclaved, but not Amphotericin B-kill...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436927
更新日期:1989-04-01 00:00:00
abstract::The influx of inflammatory cells towards the peritoneal cavity in rats inoculated intraperitoneally with subcellular preparations of the fungus Paracoccidioides brasiliensis was studied. In addition to the dead fungus, also fractions F1 of the cell wall, which mainly consisted of polysaccharides and the lipid extract,...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00437324
更新日期:1987-01-01 00:00:00
abstract::The systematic human hair degradation by Trichophyton terrestre was examined by electron and light microscopy. The cuticular and hair shaft regions were readily decomposed by the wild type or parent strain selected for phenotype studies after exposure to spaceflight parameters. ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00491505
更新日期:1975-06-14 00:00:00
abstract::Recently, Trichosporon taxonomy has been reevaluated and new genera of the Trichosporonaceae family have been described. Here, 26 clinical isolates were submitted for identification via sequencing of the intergenic space 1 (IGS1) region, genotyping, and investigation of virulence factors. Antifungal susceptibility was...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-019-00407-x
更新日期:2020-04-01 00:00:00
abstract::Two distinct patterns of immune recovery inflammatory syndrome (IRIS) are recognized, paradoxical and unmasking IRIS. Here we raise some concerns regarding the first case of neuroPCM-IRIS published to date, as recently proposed by Almeida and Roza (Mycopathologia 177:137-141, 2017) for a patient originally described b...
journal_title:Mycopathologia
pub_type: 评论,杂志文章
doi:10.1007/s11046-017-0230-9
更新日期:2018-06-01 00:00:00
abstract::Talaromyces marneffei, previously known as Penicillium marneffei, is the most important pathogenic thermally dimorphic fungus causing systemic mycosis in Southeast Asia. Traditionally, T. marneffei infection in human was mainly associated with acquired immunodeficiency syndrome caused by HIV infection. In recent years...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-017-0239-0
更新日期:2018-06-01 00:00:00
abstract::Six water-soluble nystatin-polyvilnylpyrrolidone complexes with respective MW of 10 kDa (NC1), 25 kDa (NC2), 30 kDa (NC3), 40 kda (NC4), 90 kDa (NC5), 360 kDa (NC6) were synthesized. The activity of the complexes was compared with that of nystatin against growth and spore germination of Fusarium oxysporum f.sp. radici...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/a:1015252121285
更新日期:2002-01-01 00:00:00
abstract::The natural reservoir of Histoplasma capsulatum var. duboisii, the etiological agent of histoplasmosis duboisii (African histoplasmosis) is not yet known. We report the isolation of H. capsulatum var. duboisii from soil admixed with bat guano and from the intestinal contents of a bat in a sandstone cave in a rural are...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF01102915
更新日期:1994-09-01 00:00:00
abstract::A simple technique of epicutaneous inoculation of guinea-pigs making use of a polyethylene chamber stuck to the animal's skin with the Duracryl resin is described. In this way, inoculation with a defined number of fungal elements is made possible. ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00627875
更新日期:1976-10-22 00:00:00
abstract::Denture stomatitis is a common inflammatory disorder of the palatal mucosa amongst denture wearers. The pathological changes are induced by Candida albicans biofilm on the fitting surface of the upper denture, and different individuals experience different levels of disease. C. albicans is known to produce secreted as...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-012-9522-2
更新日期:2012-07-01 00:00:00
abstract::Infections by Cunninghamella bertholletiae have been on the increase in recent years. However, little is known about this fungus and its infection. To clarify the pathogenicity of C. bertholletiae, we made a murine model, and to our knowledge, the first infectious model of this fungus. ICR mice pretreated with cortiso...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/a:1007095831301
更新日期:1998-01-01 00:00:00
abstract:BACKGROUND:Cryptococcal meningitis is one of the most important opportunistic infection and a major contributor to early mortality. In sub-Saharan Africa, particularly in Senegal, prevalence of cryptococcal meningitis remains high. This study aimed to describe the epidemiology, laboratory profile, therapeutic and outco...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-013-9710-8
更新日期:2013-12-01 00:00:00
abstract::Melanin is a complex polymer which is secreted outside or constitutes the structure of fungal cell wall. It is considered as an important virulence factor in opportunistic pathogenic fungi. In this study, one albino mutant (CBS 125149) was generated from a parent meristematic mutant (CBS 122845) of Fonsecaea monophora...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-012-9588-x
更新日期:2013-06-01 00:00:00
abstract::The strain ZK7 of Pochonia chlamydosporia var. chlamydosporia and IPC of Paecilomyces lilacinus are highly effective in the biological control against root-knot nematodes infecting tobacco. When applied, they require a specific monitoring method to evaluate the colonization and dispersal in soil. In this work, the ran...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-006-0013-1
更新日期:2006-05-01 00:00:00
abstract::Lipase (Glycerol ester hydrolase E.G. 3.1.1.3) from a Brazilian strain of Penicillium citrinum free of the mycotoxin citrinin has been investigated. Citrinin production was inhibited by using culture medium containing olive oil, soybean oil and corn oil as carbon sources. Potassium concentration and pH play an importa...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00439123
更新日期:1996-02-01 00:00:00
abstract::Malbranchea gypsea IMI 338,168 isolated from the soils of Keoladeo National Park, Bharatpur was studied for its ability to produce exocellular proteases on glucose-gelatin medium at pH 7; 28 degrees C. The fungus was observed to be a potent producer of such enzymes. Protease production was optimal at 15 days of incuba...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1023/a:1006968600404
更新日期:1998-01-01 00:00:00
abstract::A case of mycetoma caused by the black fungus Madurella grisea in northern Brazil is reported. The lesion was located on the patient's right foot without bone involvement. Clinical samples were collected by opening the fistules with a scalp and the grains removed for microbiological and histopathological analyses. Alt...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-004-2844-y
更新日期:2004-11-01 00:00:00
abstract::Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was dia...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-019-00335-w
更新日期:2019-06-01 00:00:00
abstract::Cutaneous aspergillosis is a common systemic mycosis affecting immunosuppressed patients. Here, we describe a novel morphological type of cutaneous aspergillosis in a young immunocompetent woman who presented with a chronic history of multiple nodules and discharging sinuses over left side of the face, mimicking cervi...
journal_title:Mycopathologia
pub_type: 杂志文章,评审
doi:10.1007/s11046-014-9732-x
更新日期:2014-04-01 00:00:00
abstract:BACKGROUND:Chronic rhinosinusitis (CRS) with eosinophilic mucin is considered rare in Korea. The object of this study was to categorize CRS patients with eosinophilic mucin into several groups and compared the groups based on their clinicopathological and radiological features. METHODS:In total, 105 CRS patients with ...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-019-00340-z
更新日期:2019-06-01 00:00:00
abstract::Two cases of sporothricosis originating from the same geographical area (Province of Barcelona) are described, including the circumstances of infection and the isolation of a wild strain of Sporothrix schenckii at the same locality. This finding could classify this particular area as a zone of interest in the epidemio...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/BF00436679
更新日期:1987-07-01 00:00:00
abstract::The taxonomic position of the causal agent of fruit rot of olives was determined from fresh collections of the fungus from central Greece. In culture it formed two types of conidia, namely fusiform, hyaline, aseptate conidia typical of the genus Fusicoccum, and dark-walled, ovoid, ellipsoid or fusiform, 1-2 septate co...
journal_title:Mycopathologia
pub_type: 杂志文章
doi:10.1007/s11046-005-0256-2
更新日期:2005-04-01 00:00:00