Abstract：
:Colletotrichum species are known as important pathogens of plants with an impact on crop production. Some of these species are also known as a cause of rare ophthalmic infections in humans. A case of keratitis caused by Colletotrichum dematium after corneal trauma in a 56-year-old woman is presented. Infection was diagnosed based on positive microscopy and culture. The fungal isolate was identified by morphological characteristics and DNA sequencing of the ITS rDNA region, β-tubulin (tub2) and glyceraldehyde-3-phosphate dehydrogenase (gapdh) genes. The patient responded well to topical therapy with amphotericin B combined with intravenous amphotericin B but improvement was associated with the corneal collagen cross-linking. The review of the literature revealed another 13 cases of C. dematium keratitis, all but one patient having at least one keratitis risk factor in their history. Almost all patients (n = 12) were treated with topical polyene antibiotics (natamycin or amphotericin B), improvement and cure were achieved in eight of them.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Buchta V,Nekolová J,Jirásková N,Bolehovská R,Wipler J,Hubka Vdoi
10.1007/s11046-019-00335-wsubject
Has Abstractpub_date
2019-06-01 00:00:00pages
441-453issue
3eissn
0301-486Xissn
1573-0832pii
10.1007/s11046-019-00335-wjournal_volume
184pub_type
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