Abstract:
:The aim of this study was to detect antibodies against Paracoccidioides brasiliensis in dogs seropositive and seronegative for leishmaniasis. Sera from 836 dogs (449 positive and 387 negative to leishmaniasis) were analysed by ELISA and the immunodiffusion test using gp43 and exoantigen, respectively. The analysis of the 836 serum samples by ELISA and the immunodiffusion test showed a positivity of 67.8 % and 7.3%, respectively, for P. brasiliensis infection. The dogs positive to leishmaniasis showed a higher reactivity to gp43 (79.9%) and exoantigen (12.7%) than the negative ones (54.0% and 1.0%, respectively). The higher reactivity to P. brasiliensis antigens may be due to cross-reactivity or a co-infection of dogs by Leishmania and P. brasiliensis. The lower correlation (0.187) observed between reactivity to gp43 and Leishmania antigen reinforces the latter hypothesis.
journal_name
Mycopathologiajournal_title
Mycopathologiaauthors
Silveira LH,Domingos IH,Kouchi K,Itano EN,Silva EA,Landgraf VO,Werneck SM,Camargo ZP,Ono MAdoi
10.1007/s11046-006-0046-5subject
Has Abstractpub_date
2006-11-01 00:00:00pages
325-9issue
5eissn
0301-486Xissn
1573-0832journal_volume
162pub_type
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