Prognostic Potential of the Panfungal Marker (1 → 3)-β-D-Glucan in Invasive Mycoses Patients.

Abstract:

:We analyze the prognostic potential of (1 → 3)-β-D-glucan (BG) levels in predicting clinical outcomes in patients with invasive fungal infections, on a population undergoing 253 episodes (177 with positive and 76 with negative outcome). Using linear regression analysis, we assessed the prognostic potential of kinetically evaluated BG levels and we found an overall sensitivity and specificity of 68 and 82%, respectively. Moreover, using an interpretative algorithm based on two distinct cutoff values, we were able to predict the outcome in 84% of the studied population with a diagnostic accuracy of 82%.

journal_name

Mycopathologia

journal_title

Mycopathologia

authors

Pini P,Venturelli C,Girardis M,Forghieri F,Blasi E

doi

10.1007/s11046-018-0282-5

subject

Has Abstract

pub_date

2019-02-01 00:00:00

pages

147-150

issue

1

eissn

0301-486X

issn

1573-0832

pii

10.1007/s11046-018-0282-5

journal_volume

184

pub_type

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